Medical Specialties Commons^™

Pediatric Ppi Use And Fractures, Nathan R. Fleishman Md, Thomas M. Attard, Troy E. Richardson

Research Days

No abstract provided.

Clinical Utility Of Exon Deletion/Duplication Microarray Testing - A Children’S Mercy Kansas City Two-Year Experience, Binu Porath

Research Days

No abstract provided.

Provider Education And Rapid Antigen Detection Test Use In An Academic Pediatric Clinic, Steven Dahl

Research Days

No abstract provided.

Attitudes Of Emergency Medical Service (Ems) Providers Towards Pediatric Death And Outside-Of-Hospital Do Not Resuscitate (Dnr) Orders, Clay Yaklin

Research Days

No abstract provided.

Adhd Clinic Outcomes: Assessing Dose Response Over Time, Caroline Pittard

Research Days

No abstract provided.

Prevalence Of Sexual Minorities Among Adolescents Evaluated For Polycystic Ovary Syndrome, Cintya Schweisberger

Research Days

No abstract provided.

Changes In Pt, Aptt And Platelet Counts After Ich Resulting From Accidental Trauma, Sara Kilbride

Research Days

No abstract provided.

Racial/Ethnic Demographics Of Participants In Clinical Trials Of Biologics Used For Asthma, Susamita Kesh

Research Days

No abstract provided.

Parental Observation Of Environmental Exposures In The Home Of Children With Asthma, Hannah N. Neuhaus

Research Days

No abstract provided.

Initial Evaluation Of Adolescent Females Hospitalized With Heavy Menstrual Bleeding, Lauren Amos Md

Research Days

No abstract provided.

Guided Mentorship: Enhancing Pediatric Resident’S Skills In Cardiopulmonary Resuscitation, Alyssa Stoner

Research Days

No abstract provided.

Characterization Of Low Resource Utilization Observation Status Hospitalizations Within Children's Hospitals, David C. Synhorst

Research Days

No abstract provided.

Impact Of A Mobile Device-Based Clinical Decision Support Tool On Guideline Adherence And Mental Workload Among Trainee And Attending Physicians, Katherine M. Richardson

Presentations

This study evaluated PedsGuide, an app used to evaluate serious bacterial infections in febrile infants.

Individual Free Fatty Acids Have Unique Associations With Inflammatory Biomarkers, Insulin Resistance And Insulin Secretion In Healthy And Gestational Diabetic Pregnant Women., Xinhua Chen, T Peter Stein, Robert A Steer, Theresa O Scholl

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Objective: We investigated the relationships of maternal circulating individual free fatty acids (FFA) with insulin resistance, insulin secretion and inflammatory biomarkers during mid-pregnancy.

Research design and methods: The data were drawn from a prospective cohort of generally healthy pregnant women (n=1368, African-American 36%, Hispanic 48%, Caucasian 16%) in Camden, NJ. We quantitatively determined 11 FFAs, seven cytokine/adipokine, homeostatic model assessment of insulin resistance (HOMA-IR) and C-peptide levels from the fasting blood samples that were collected at 16 weeks of gestation. Multivariate analyses were performed along with separate analyses for each individual FFA.

Results: High HOMA-IR (p

Conclusion: Our results suggest …

Should A Fully Covered Self-Expandable Biliary Metal Stent Be Anchored With A Double-Pigtail Plastic Stent? A Retrospective Study, Saad Emhmed Ali, Wesam M. Frandah, Leon Su, Cory Fielding, Houssam Mardini

Internal Medicine

Background: The migration rate of fully covered self-expandable metal stents (FCSEMSs) has been reported to be between 14% to 37%. Anchoring of FCSEMSs using a double-pigtail plastic stent (DPS) may decrease migration. Aim: To compare stent migration rates between patients who received FCSEMS alone and those who received both an FCSEMS and anchoring DPS. Methods: We conducted a retrospective analysis of endoscopy reporting system and medical records of 1366 patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) with FCSEMS placement at the University of Kentucky health care. Between July 2015 and April 2017, 203 patients with FCSEMS insertion for the treatment …

A High-Throughput Screen Indicates Gemcitabine And Jak Inhibitors May Be Useful For Treating Pediatric Aml, Christina D. Drenberg, Anang Shelat, Jinjun Dang, Anitria Cotton, Shelley J. Orwick, Mengyu Li, Jae Yoon Jeon, Qiang Fu, Daelynn R. Buelow, Marissa Pioso, Shuiying Hu, Hiroto Inaba, Raul C. Ribeiro, Jeffrey E. Rubnitz, Tanja A. Gruber, R. Kiplin Guy, Sharyn D. Baker

Pharmaceutical Sciences Faculty Publications

Improvement in survival has been achieved for children and adolescents with AML but is largely attributed to enhanced supportive care as opposed to the development of better treatment regimens. High risk subtypes continue to have poor outcomes with event free survival rates < 40% despite the use of high intensity chemotherapy in combination with hematopoietic stem cell transplant. Here we combine high-throughput screening, intracellular accumulation assays, and in vivo efficacy studies to identify therapeutic strategies for pediatric AML. We report therapeutics not currently used to treat AML, gemcitabine and cabazitaxel, have broad anti-leukemic activity across subtypes and are more effective relative to the AML standard of care, cytarabine, both in vitro and in vivo. JAK inhibitors are selective for acute megakaryoblastic leukemia and significantly prolong survival in multiple preclinical models. Our approach provides advances in the development of treatment strategies for pediatric AML.

Should A Fully Covered Self-Expandable Biliary Metal Stent Be Anchored With A Double-Pigtail Plastic Stent? A Retrospective Study, Saad Emhmed Ali, Wesam M. Frandah, Leon Su, Cory M. Fielding, Houssam Mardini

Internal Medicine Faculty Publications

BACKGROUND

The migration rate of fully covered self-expandable metal stents (FCSEMSs) has been reported to be between 14% to 37%. Anchoring of FCSEMSs using a double-pigtail plastic stent (DPS) may decrease migration.

AIM

To compare stent migration rates between patients who received FCSEMS alone and those who received both an FCSEMS and anchoring DPS.

METHODS

We conducted a retrospective analysis of endoscopy reporting system and medical records of 1366 patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) with FCSEMS placement at the University of Kentucky health care. Between July 2015 and April 2017, 203 patients with FCSEMS insertion for the treatment …

Challenges Of Training And Delivery Of Pediatric Surgical Services In Developing Economies: A Perspective From Pakistan, Amir Humza Sohail, Muhammad Hassaan Arif Maan, Mohammed Sachal, Muhammad Soban

Medical College Documents

Background: As the pediatric population requiring health services rises globally, developing countries are struggling to cater to the growing burden of non-communicable diseases - particularly those requiring specialized surgical care.
Main body: Despite the literature supporting specialized pediatric surgical care, the developing world is far from meeting the American Pediatric Surgical Association (APSA) Manpower taskforce recommendation of at least 1 qualified pediatric surgeon per 100,000 patients (0-15 years-old). In Pakistan, there is an unmet surgical need in the pediatric population due to a multitude of short shortcomings, notably in quality and quantity of the training programs on offer, and urgent …

The Effects Of Hip Tightness On Running Mechanics And The Fms Deep Squat In Diii Track & Field Runners, Sam Rosario

Augsburg Honors Review

Running requires rapid hip movements. Increasing running speeds place increased loads on hip flexor and extensor muscles (Schache et al., 2011). It is unclear whether Division III track and field athletes with self-reported hip tightness would present altered sagittal plane hip mechanics while running and functional limitations when performing the Functional Movement Screen (FMS) deep squat. Objective: To investigate the relationship between hip tightness, as measured by the Functional Movement Screen (FMS) deep squat (DS), and running mechanics, as measured by the peak flexion and extension angles in Division III Track & Field athletes. Methods: Ten subjects completed the FMS …

The Effect Of Antihypertensive Medications Dosing On Blood Pressure Control And Left Ventricular Hypertrophy In Children With Chronic Kidney Disease, Benjamin A. Matta

Research Days

No abstract provided.

Relationship Between Hemolytic Index Early In Life And Development Of Abnormal Transcranial Doppler Velocities In Pediatric Patients With Sickle Cell Anemia, Derrick L. Goubeaux

Research Days

No abstract provided.

Methotrexate Polyglutamates And The Potential Role In Pediatric Inflammatory Bowel Disease, Ryan Morrow

Research Days

No abstract provided.

Maximal Oxygen Consumption Recovery Delay In A Fontan Population, Karoline Krzywda

Research Days

No abstract provided.

Effect Of Crohn’S Disease On Villous Length And Cyp3a4 Expression In The Pediatric Small Intestine, Brian D. Chapron

Research Days

No abstract provided.

Does Palliative Care Involvement Influence Location Of Death?, Joy L. Solano

Research Days

No abstract provided.

Predictive Performance Of Existing Population Pharmacokinetic Models Of Tacrolimus In Pediatric Kidney Transplant Recipients, Alenka Chapron

Research Days

No abstract provided.

Thyrotoxicosis Presenting With Nondiabetic Ketoacidosis In A 4 Year Old Female, Henry S. Jeng Dr

Research Days

No abstract provided.

Lymphocytic Lobulitis Presenting In An Adolescent Female: A Case Report, Kevin Meilak Md

Research Days

No abstract provided.

Characterization Of The Relative Contribution Of Cyp2d6 And Cyp3a4 To The Metabolism Of Pimozide, Brian D. Chapron

Research Days

No abstract provided.

Cd30-Positive, Ebv-Positive T-Cell Lymphoma Associated With Chronic Active Ebv Infection: Successful Treatment With Brentuximab Vedotin, Sarah E. Mc Dermott

Research Days

No abstract provided.