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Journal of Medicine in Scientific Research

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Full-Text Articles in Medical Specialties

Cardiovascular Risk In Patients With Rheumatoid Arthritis: The Role Of Cholesterylester Transfer Protein, Ali M. Mursi, Emad M. Elshebiny, Lobna Y. Ebrahim, Sahar H. Quashwa, Sherry K. Abdelrahman, Taghreed F. Mohammed Mostafa Dec 2019

Cardiovascular Risk In Patients With Rheumatoid Arthritis: The Role Of Cholesterylester Transfer Protein, Ali M. Mursi, Emad M. Elshebiny, Lobna Y. Ebrahim, Sahar H. Quashwa, Sherry K. Abdelrahman, Taghreed F. Mohammed Mostafa

Journal of Medicine in Scientific Research

Aim To detect serum level of cholesterylester transfer protein (CETP) (the enzyme involved in reverse cholesterol transport) in patients with rheumatoid arthritis (RA) and to evaluate its relation to various clinical parameters of the disease, lipid profile, and carotid intima-media thickness (CIMT) as a marker of atherosclerosis and cardiovascular disease risk. Patients and methods This study involved a total of 80 participants, comprising 50 patients with RA and 30 age-matched and sex-matched healthy controls. Detailed medical history and thorough clinical examination (general and musculoskeletal) as well as laboratory investigations including lipid profile were performed for all patients with RA. Serum …


Determinants Of Infarction Patterns In Posterior Cerebral Circulation, Ahmed H. T Badr Ahmed, Mohamed M. Fouad, Ramez R. Moustafa, Taha K. Alloush Dec 2019

Determinants Of Infarction Patterns In Posterior Cerebral Circulation, Ahmed H. T Badr Ahmed, Mohamed M. Fouad, Ramez R. Moustafa, Taha K. Alloush

Journal of Medicine in Scientific Research

Background Ischemic stroke is defined as focal or global neurological dysfunction lasting longer than 24 h or leading to death that is caused by vascular insult, either stricture or occlusion of a specific vascular territory. Aim of the study This study aimed to determine the relationship between different risk factors and different infarction patterns in posterior circulation such single small lacunar lesion, single large lesion, and multiple scattered lesions. Patients and methods This study included 60 patients recruited from the stroke unit of Ain Shams University and El Sahel Teaching Hospitals during the period from April to October 2018 with …


Additive Value Of Intraoperative Hemodynamic Monitoring To Epicardial Echocardiography During Surgical Repair Of Children With Congenital Heart Disease, Ahmed A. Algebaly, Hanan Mohammed Hassan, Rania D. Eldin Abou Shokka Dec 2019

Additive Value Of Intraoperative Hemodynamic Monitoring To Epicardial Echocardiography During Surgical Repair Of Children With Congenital Heart Disease, Ahmed A. Algebaly, Hanan Mohammed Hassan, Rania D. Eldin Abou Shokka

Journal of Medicine in Scientific Research

Aim The aim was to evaluate the additive value of intraoperative hemodynamic monitoring to epicardial echocardiography on the surgical outcome in children undergoing surgical correction of congenial heart disease. Patients and methods This study was conducted on 238 children with congenital heart disease who were enrolled for surgical correction. They were arranged in two groups: group A included 159 children in whom e-echo was used to detect intraoperative residual lesions while group B included 79 patients in whom e-echo and intraoperative hemodynamic monitoring using oxygen saturation step-up and intracardiac pressures after disconnection of cardiopulmonary bypass to detect residual shunt flow …


A Comparison Between Monopolar Radiofrequency Ablation And Electrocautery (Diathermy) Ablations In Left Modified Maze (Short-Term Results), Waleed El-Awady Dec 2019

A Comparison Between Monopolar Radiofrequency Ablation And Electrocautery (Diathermy) Ablations In Left Modified Maze (Short-Term Results), Waleed El-Awady

Journal of Medicine in Scientific Research

Introduction Atrial fibrillation is the most common cardiac arrhythmia and is associated with significant morbidity and mortality. The classic cut-and-sew maze procedure is successful in 85–95% of patients. However, it is technically challenging and requires prolonged cardiopulmonary bypass. The left modified maze procedure is successful in 65–85% of patients. The aim of this study was to compare the success of two different ablation sources in the left modified MAZE. Patients and methods Between June 2010 and December 2016, 40 patients underwent left modified MAZE (Cox III) procedure: 20 patients were done with monopolar radiofrequency ablation (group A) and the other …


Role Of Arginine And/Or Taurine In Protection Against Gentamicin-Induced Nephrotoxicity In Male And Female Rats, Amal H. Emara, Wafaa M. Ismaeil Dec 2019

Role Of Arginine And/Or Taurine In Protection Against Gentamicin-Induced Nephrotoxicity In Male And Female Rats, Amal H. Emara, Wafaa M. Ismaeil

Journal of Medicine in Scientific Research

Background As a highly effective antibiotic, gentamicin is used in the treatment of serious and life-threatening gram-negative infections. L-arginine (2-amino-5-guanidino-pentanoic acid) has a protective role on renal failure that induced by gentamicin administration and it may decrease the tubular reabsorption of another cationic substance, gentamicin due to its cationic structure. The aim of this study is to determine the influence of gender on nephroprotective effects of L-arginine (Arg) and/or taurine (Tau) on gentamicin (G) induced nephrotoxicity. Methods Adult Sprague-Dawley albino rats of both sexes (150-200 g, 48 male and 48 female), were bred from the animal unit of National Nutrition …


Glutamic Acid Decarboxylase Auto-Antibodies Prevalence Among Patients With Type 2 Diabetes Mellitus And Their Clinical Characteristics In A Sample Of The Egyptian Population, Atef A. Bassyounia, Ayat I. Ghanem, Ghada A. Omar Dec 2019

Glutamic Acid Decarboxylase Auto-Antibodies Prevalence Among Patients With Type 2 Diabetes Mellitus And Their Clinical Characteristics In A Sample Of The Egyptian Population, Atef A. Bassyounia, Ayat I. Ghanem, Ghada A. Omar

Journal of Medicine in Scientific Research

Background Patients with latent autoimmune diabetes in adults may develop early loss of β-cell mass. They are often misdiagnosed as having type 2 diabetes mellitus (T2DM). This is because latent autoimmune diabetes in adults condition does share characteristics of both type 1 and T2DM. Aim To estimate the prevalence of unrecognized cases with glutamic acid decarboxylase auto-antibodies (GADA) among patients with T2DM in a sample of the Egyptian population, describing their clinical and laboratory features, and investigating the relationship with chronic complications of diabetes. Settings and design A total of 1515 Egyptian patients previously diagnosed as having T2DM were divided …


Recent Conservative Management Trends In Dealing With Uterine Adnexal Torsion Will Preserve Fertility In Childbearing Women: A Review Of Literature And Case Series, Hossam H. Soliman Dec 2019

Recent Conservative Management Trends In Dealing With Uterine Adnexal Torsion Will Preserve Fertility In Childbearing Women: A Review Of Literature And Case Series, Hossam H. Soliman

Journal of Medicine in Scientific Research

Introduction Uterine adnexal torsion is a rare gynecologic emergency, representing 2.5–7% of all the acute gynecologic surgical conditions. It could lead to adnexal ischemia and necrosis, putting a woman at the risk of a radical surgery, which leads her to lose a uterine adnexa, plummeting her future fertility, and possibility inducing a negative effect of her future marital and family life. Adnexal detorsion associated with cystectomy is a simple maneuver that could spare the woman of losing her ovary; this technique could successfully work even with an apparently necrosed ovary. Aim A review of literature, in addition to a retrospective …


Surgical Outcomes Of Obstructive Mechanical Valve Thrombosis, Risk Factors, And Comorbidity Analysis, Ahmed Shafeek Ali Dec 2019

Surgical Outcomes Of Obstructive Mechanical Valve Thrombosis, Risk Factors, And Comorbidity Analysis, Ahmed Shafeek Ali

Journal of Medicine in Scientific Research

Background Obstructive mechanical valves thrombosis is a life-threatening complication associated with high morbidity and mortality. Although thrombolytic therapy has gained a lot of popularity in recent years, yet the treatment of choice is still controversial. Objective The aim of this study was to evaluate the outcomes of patients who underwent redo valve surgery for obstructive mechanical valve thrombosis. Patients and methods Outcomes of 380 patients who underwent emergency redo surgery for obstructive mechanical valve thrombosis at our institute during a 5-year period (January 2012 to December 2017) were reviewed retrospectively. Clinical symptoms and transthoracic echocardiography were the mainstay in diagnosis. …


Retrograde Transcatheter Closure Of Perimembranous Aneurysmal Ventricular Septal Defects Using Amplatzer Vascular Plug Ii, Ahmed A. Al Gebaly, Rania Diaa Abou Shokka, Wael M. Hossam Dec 2019

Retrograde Transcatheter Closure Of Perimembranous Aneurysmal Ventricular Septal Defects Using Amplatzer Vascular Plug Ii, Ahmed A. Al Gebaly, Rania Diaa Abou Shokka, Wael M. Hossam

Journal of Medicine in Scientific Research

Introduction Retrograde transcatheter closure of perimembranous aneurysmal ventricular septal defects (pmVSD) can be a better option for transcatheter closure of ventricular septal defect with device placement into ventricular septal aneurysm with fewer complications. Also, a retrograde approach might decrease procedure time and radiation exposure time. Aim The purpose of this study was to report off-label experience using Amplatzer Vascular Plug II (AVPII) for the trans catheter closure of perimembranous aneurysmal VSD. Comparison of haemodynamic effects of ketamine and sevofluorane as in induction of anesthesia. Materials and methods Our series consists of a fifteen child with pmVSD. The mean age was …


One-Year Angiographic Results Of Left Anterior Descending Bypass Using Internal Mammary Artery: A Series Of 48 Consecutive Patients, Ahmed S. Mahlab Dec 2019

One-Year Angiographic Results Of Left Anterior Descending Bypass Using Internal Mammary Artery: A Series Of 48 Consecutive Patients, Ahmed S. Mahlab

Journal of Medicine in Scientific Research

The left internal mammary artery (LIMA) has been used as a conduit for coronary artery revascularization since 1968. Here we are reporting A total of 48 consecutive patients were operated upon using double mammary arteries. All of them received a mammary graft to the left anterior descending artery (LAD). All 48 of them were controlled angiographically at 1 year postoperative to ensure satisfactory well-functioning grafts.


Ruptured Inferior Mesenteric Artery Aneurysm: A Case Report, Assem Mohamed Herzallah Dec 2019

Ruptured Inferior Mesenteric Artery Aneurysm: A Case Report, Assem Mohamed Herzallah

Journal of Medicine in Scientific Research

Among visceral artery aneurysms, inferior mesenteric artery aneurysm is the rarest. Although most cases are of degenerative etiology, a small fraction of these cases are caused by autoimmune diseases. We report a case of spontaneous retroperitoneal hemorrhage from a ruptured inferior mesenteric artery aneurysm in a 30-year-old patient with systemic lupus erythematosus, treated by ligation.


Cardiac Dysfunction In Patients With Community-Acquired Pneumonia, Ehab Elmelegy, El-Saied Shaheen, Wael Hossam El Din Nov 2019

Cardiac Dysfunction In Patients With Community-Acquired Pneumonia, Ehab Elmelegy, El-Saied Shaheen, Wael Hossam El Din

Journal of Medicine in Scientific Research

Background Community-acquired pneumonia (CAP) is still an important cause of morbidity and mortality worldwide especially in the elderly. Evidence shows a high correlation between acute respiratory infections and increased risk of cardiovascular events (CVEs). The occurrence of CVE in hospitalized patients with CAP may significantly affect the clinical status, and a severe CVE could be the primary cause of clinical failure. Aim To study the incidence of cardiac complications in patients with CAP. Patients and methods This clinical study was carried out on 120 patients (63 males and 57 females) hospitalized with a primary diagnosis of CAP. Patients with the …


Rare Presentation Of Typhoid Fever In An Immunocompetent Patient, Kumar Priyanka, Rajnish Kumar Nov 2019

Rare Presentation Of Typhoid Fever In An Immunocompetent Patient, Kumar Priyanka, Rajnish Kumar

Journal of Medicine in Scientific Research

Typhoid fever, caused by Salmonella enterica serovar Typhi, is the most common cause of enteric fever, and presents classically with fever and other gastrointestinal symptoms. We report an interesting case of a 27-year-old Indian man who lives in a semiurban area of Haryana (northern India) and presented with a 3-day-long history of intermittent fever, chills, and rigor. He was misdiagnosed previously as having mumps fever in view of the clinical presentation, but later, with proper workup, it was found to be an atypical presentation of typhoid fever. He responded well to intravenous antibiotics and recovered completely from typhoid infection.


Relationship Between Dietary Intake And Obesity Among A Group Of Primary School‑Aged Children In Cairo Governorate, Mahmood D. Al‑Mendalawi Nov 2019

Relationship Between Dietary Intake And Obesity Among A Group Of Primary School‑Aged Children In Cairo Governorate, Mahmood D. Al‑Mendalawi

Journal of Medicine in Scientific Research

Sir,
I read with interest the study by El‑Gazzar et al. [1] published in January–March 2019 issue of the Journal of Medicine in Scientific Research. Based on using WHO growth standard to measure various anthropometric indices as well as dietary assessment (24 h recall) and food consumption pattern, the authors studied the relationship between dietary pattern and obesity among a cohort of Egyptian primary school children. They found a positive correlation between obesity and the increased intake of high‑energy dense food (fat and sugar) in the studied cohort. Owing to the presence of the following methodological limitation, I presume that …


Endoscopic Band Ligation Versus Argon Plasma Coagulation In Management Of Bleeding From Gastric Antral Vascular Ectasia In Patients With Portal Hypertension, Hala M. Abd El Maguid, Muhammad M. Abdel Ghaffar Nov 2019

Endoscopic Band Ligation Versus Argon Plasma Coagulation In Management Of Bleeding From Gastric Antral Vascular Ectasia In Patients With Portal Hypertension, Hala M. Abd El Maguid, Muhammad M. Abdel Ghaffar

Journal of Medicine in Scientific Research

Background Gastric antral vascular ectasia (GAVE) may cause recurrent hemorrhage, and thus, chronic anemia, in patients with portal hypertension. Treatment with argon plasma coagulation (APC) is an effective and safe method in adults but requires multiple sessions of endoscopic therapy. Endoscopic band ligation (EBL) was found to be a good alternative for APC as a treatment for GAVE, especially in refractory cases. The aim of this prospective study was to evaluate the safety and efficacy of EBL, as compared with APC, in treating nonvariceal upper GI bleeding GAVE in patients with portal hypertension. Patients and methods A total of 40 …


Using Ondansetron As An Oral Premedication Drug For Prevention Of Postanesthesia Shivering, Ashraf A. M. Soliman Nov 2019

Using Ondansetron As An Oral Premedication Drug For Prevention Of Postanesthesia Shivering, Ashraf A. M. Soliman

Journal of Medicine in Scientific Research

Introduction Postanesthesia shivering (PAS) is one of the most common complications after surgeries. There are two methods to reduce the shivering, including pharmacological and nonpharmacological methods. Aim This study compared the efficacy and safety of 4-mg oral ondansetron premedication on preventing PAS, perioperative core body temperature changes, and hemodynamic stability. Patients and methods This prospective, observational study consisted of 100 adult patients scheduled for general surgery or interventional structural heart disease. The patients were randomized into two groups of 50 patients each. Group I received 4 mg of oral ondansetron, and group II received an oral placebo 60–90 min before …


Haptoglobin Genotyping And Risk Of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage, Ahmed M. Ateya, Ahmed A. El-Bassiouny, Islam El-Garwany, Khaled Gobbah, Mahmoud H. Ibrahim, Nagia A. Fahmy, Sobhy H. El-Nabi Nov 2019

Haptoglobin Genotyping And Risk Of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage, Ahmed M. Ateya, Ahmed A. El-Bassiouny, Islam El-Garwany, Khaled Gobbah, Mahmoud H. Ibrahim, Nagia A. Fahmy, Sobhy H. El-Nabi

Journal of Medicine in Scientific Research

Background Aneurysmal subarach noid hemorrhage (aSAH) represents roughly 6–8% of all stroke types. Almost 70% of patients develop angiographic vasospasm, and 30% of them will have delayed cerebral ischemia (DCI). An 'omic signature' could combine genetic, proteomic, and metabolomic phenotypes into an accurate predictive model. Haptoglobin (Hp) genotypes could be used to stratify risk of resulting cerebral vasospasm (CV) and DCI, to give prognostic data dependent on distributed result probabilities, and to develop novel medications dependent on individual pathophysiological models. Objective This research intends to investigate the clinical and radiological factors as indicators for risk of development of CV after …


Role Of Triphasic Computed Tomography In Prediction Of Response To Transcatheter Arterial Chemoembolization In Unresectable Hepatocellular Carcinoma Patients, Ahmed A.E Hassan Desoky, Hala M. Maghraby, Mohammed K. Omar Nov 2019

Role Of Triphasic Computed Tomography In Prediction Of Response To Transcatheter Arterial Chemoembolization In Unresectable Hepatocellular Carcinoma Patients, Ahmed A.E Hassan Desoky, Hala M. Maghraby, Mohammed K. Omar

Journal of Medicine in Scientific Research

Background The initial approach in the management of hepatocellular carcinoma (HCC) is to determine if either surgical resection or liver transplantation is feasible. Unfortunately, more than three-quarters of the patients are diagnosed during the intermediate or advanced stages of the disease and are considered ineligible for curative resection. Transarterial chemoembolization (TACE) is the current standard of therapy for patients with intermediate-stage HCC according to the Barcelona Clinic Liver Cancer classification. Aim This study aims to evaluate the role of triphasic computed tomography (CT) in the prediction of the prognosis of irresectable HCC patients, who had been locally treated with TACE …


Role Of Pomegranate Peel On Ameliorated Hyperglycemia And Hypercholesterolemia In Experimental Rats, Magda Ramzy Nov 2019

Role Of Pomegranate Peel On Ameliorated Hyperglycemia And Hypercholesterolemia In Experimental Rats, Magda Ramzy

Journal of Medicine in Scientific Research

Introduction Pomegranate peels (Punica granatum) (contain fiber and antioxidants, which are beneficial to our health. This study aimed to investigate the effects of different concentrations of pomegranate peels on blood glucose, lipid profiles, and some physiological parameters, such as liver and kidney functions, in rats having diabetes and hypercholesterolemia. Methods Rats were divided into three main groups: the first main group was the negative control, the second main group was diabetic rats, and the third main group was hypercholesterolemic rats. Second and third main groups were divided into four subgroups (six rats/group) and fed with different diet levels …


Computerized Dynamic Posturography In School-Aged Children With Sensorineural Hearing Loss, Hanaa Fadel, Hoda Abu-Moussa Mina, Naema M. Ismail, Shereen Emad El Dein Abdel Moneim Nov 2019

Computerized Dynamic Posturography In School-Aged Children With Sensorineural Hearing Loss, Hanaa Fadel, Hoda Abu-Moussa Mina, Naema M. Ismail, Shereen Emad El Dein Abdel Moneim

Journal of Medicine in Scientific Research

Background According to embryological and anatomical connection between the cochlea and vestibular end-organs, children with sensorineural hearing loss (SNHL) may exhibit abnormalities of vestibular and balance function. Documentation of vestibular dysfunction in children with SNHL has a long and rich history indicating that 20–70% of children with SNHL demonstrate an element of vestibular end-organ dysfunction. Vestibular dysfunction was proved to correlate with severity of cochlear loss in many research works. Aim of the work To assess normative data of sensory organization test (SOT) and head shaking (HS) test according to age, weight, and height of children in control group and …


Comparable Study Between Organic And Nonorganic Vegetables In Their Contents Of Some Nutritive Components, Hamdy A. El-Bassel, Hany H. El-Gazzar Nov 2019

Comparable Study Between Organic And Nonorganic Vegetables In Their Contents Of Some Nutritive Components, Hamdy A. El-Bassel, Hany H. El-Gazzar

Journal of Medicine in Scientific Research

Background There is no doubt that vegetables play an essential role in human growth as they provide the human body the necessary needs of vitamins and minerals. Several analytical methods have been set up and improved to determine the quantity of vitamins and minerals in different fruits and vegetables. The purpose of this study is to evaluate the quantities of vitamins and minerals in organic and nonorganic vegetables in Egyptian. The results showed that organic tomatoes, eggplant, lettuce, squash, carrots, and cabbage had significantly higher content of vitamin C, vitamin E, β-carotene, phosphorus, and calcium. However, nonorganic vegetables showed significantly …


The Role Of Vitamin D Therapy In Patients With Fibromyalgia And Its Effect On Quality Of Life, Abeer H. Ismaiel, Aliaa El-Hady, Amal A. Mohsen, Mohamed A. Safy Nov 2019

The Role Of Vitamin D Therapy In Patients With Fibromyalgia And Its Effect On Quality Of Life, Abeer H. Ismaiel, Aliaa El-Hady, Amal A. Mohsen, Mohamed A. Safy

Journal of Medicine in Scientific Research

Objective To investigate the level of vitamin D and the effect of its therapy on quality of life in patients with fibromyalgia who had vitamin D deficiency. Patients and methods Sixty patients presenting with fibromyalgia and 30 healthy controls were studied. Patients were grouped as deficient (<20 ng/ml), inadequate (20–30 ng/ml), and sufficient (>30 ng/ml) according to the levels of vitamin D. Vitamin D replacement was performed for patients with deficiencies and inadequacies and they were assessed before and after vitamin D therapy using the following scales: visual analog scale, fibromyalgia impact questionnaire, short form-36, Arizona sexual life questionnaire, and Beck depression scale and correlation were …


Effect Of Liver Cirrhosis On Patient Outcomes From Open Heart Surgery, Ahmed A. Faragalla, Hossam B. Kashlan, Wael A. Elhakeem Nov 2019

Effect Of Liver Cirrhosis On Patient Outcomes From Open Heart Surgery, Ahmed A. Faragalla, Hossam B. Kashlan, Wael A. Elhakeem

Journal of Medicine in Scientific Research

Background We designed this prospective controlled study to evaluate the early postoperative outcomes in patients with liver cirrhosis (LC) after open heart surgery (OHS). Patients and methods Between May 2011 and February 2017, 120 patients with elective OHS were included and categorized into a control group (50%) and patients with LC (50%), who were further subdivided according to Child–Turcotte–Pugh (CTP) score into group CTP A (49 patients) and CTP B (11 patients). All preoperative demographic and clinical data in addition to operative and postoperative data were evaluated. Patients with CTP (class C) were excluded. Results Overall, 48 (40%) patients experienced …


Serum Level Of Matrix Metalloproteinase 3 (Stromelysin 1) In Patients With Systemic Lupus Erythematosus: Relation To Clinical Nephritis And Neuropsychiatric Manifestations, Eman R. Amer, Fatema A. Elshabacy, Hala A. Elhameed Tabl, Lobna Y. Ebrahim, Taghreed F. M. Mostafa Jun 2019

Serum Level Of Matrix Metalloproteinase 3 (Stromelysin 1) In Patients With Systemic Lupus Erythematosus: Relation To Clinical Nephritis And Neuropsychiatric Manifestations, Eman R. Amer, Fatema A. Elshabacy, Hala A. Elhameed Tabl, Lobna Y. Ebrahim, Taghreed F. M. Mostafa

Journal of Medicine in Scientific Research

Aim The aim of this study was to assess serum matrix metalloproteinase 3 (MMP-3) level in patients of systemic lupus erythematosus (SLE) and its relation to various clinical and laboratory findings. Patients and methods The study involved 40 female patients with SLE as a study group and 20 sex-matched and age-matched healthy individuals as a control group. All patients were subjected to thorough clinical examinations and laboratory investigations. Disease activity was assessed using SLE Disease Activity Index, as well as Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index. Serum level of MMP-3 was assessed using enzyme-linked immunosorbent assay …


Effect Of Sildenafil On Stable Chronic Heart Failure: A Prospective Randomized-Controlled Clinical Trial, Hatem Khairy, Wael Abdelatief Elhakeem Jun 2019

Effect Of Sildenafil On Stable Chronic Heart Failure: A Prospective Randomized-Controlled Clinical Trial, Hatem Khairy, Wael Abdelatief Elhakeem

Journal of Medicine in Scientific Research

Background Patients with systolic heart failure (HF) who develop secondary pulmonary hypertension have reduced exercise capacity and increased mortality compared with HF patients without pulmonary hypertension. A defective nitric oxide signaling is involved in left ventricular (LV) diastolic abnormalities and remodeling. Phosphodiesterase type 5 inhibition, by blocking degradation of nitric oxide second-messenger cyclic guanosine monophosphate, might be beneficial. Aim of the study In our study, we tested the effects of phosphodiesterase type 5 inhibition (sildenafil) on LV ejection fraction, diastolic function, pulmonary artery pressure, and clinical status. Patients, methods, and results One hundred HF patients (New York Heart Association classes …


Efficacy Of On-Pump Versus Off-Pump Coronary Artery Bypass Grafting In Early-Stage Renal Impairment Without Dialysis Therapy, Ashraf Zahra Jun 2019

Efficacy Of On-Pump Versus Off-Pump Coronary Artery Bypass Grafting In Early-Stage Renal Impairment Without Dialysis Therapy, Ashraf Zahra

Journal of Medicine in Scientific Research

Background Coronary artery disease is the most common of the cardiovascular diseases that can be treated with coronary artery bypass grafting (CABG) surgery, with either on-pump or off-pump technique. In this study, we aimed to compare the early results of isolated CABG, using on-pump and off-pump techniques, in patients with preoperative mild-to-moderate elevation of serum creatinine (1.6–2.5 mg/dl) level who did not require maintenance dialysis to support renal function. Patients and methods This prospective nonrandomized study included 60 patients who complained of symptoms of coronary artery disease and subsequently underwent myocardial revascularization at Cardiothoracic Surgery Department, Shebin El-Kom Teaching Hospital, …


A Comparative Study Between Custodiol And Warm Blood Cardioplegia In Coronary Artery Bypass Graft Operation With Poor Left Ventricular Function, Ahmed S. Ali, Hassan Mohamed Moftahb, Mohamed Ali El Ghanamb, Moustafa Gamal Eldin Moustafab, Samir Ahmed Ataa Jun 2019

A Comparative Study Between Custodiol And Warm Blood Cardioplegia In Coronary Artery Bypass Graft Operation With Poor Left Ventricular Function, Ahmed S. Ali, Hassan Mohamed Moftahb, Mohamed Ali El Ghanamb, Moustafa Gamal Eldin Moustafab, Samir Ahmed Ataa

Journal of Medicine in Scientific Research

Background Cardioplegia is responsible for myocardial protection during open heart surgery. Cardioplegia was first presented as an agent for hypothermic hyperkalemic arrest. Blood was then introduced as a vehicle to convey potassium to the heart. Custodiol Histidine-Tryptophan- ketoglutarate (HTK) solution is safe and used as a single dose, which can last for up to 3 h. The comparison of the clinical outcomes of this particular solution with warm blood cardioplegia in coronary artery bypass graft (CABG) with poor left ventricular (LV) function has received little attention. Objective To compare the clinical outcomes of custodiol solution with warm blood cardioplegia in …


Comparing Two Formulas To Estimate The Correct Depth Of The Neonatal Umbilical Venous Catheter Insertion, Hany W. G. Michael Jun 2019

Comparing Two Formulas To Estimate The Correct Depth Of The Neonatal Umbilical Venous Catheter Insertion, Hany W. G. Michael

Journal of Medicine in Scientific Research

Aim The rate of complications among neonates with incorrectly positioned umbilical venous catheters (UVCs) is considerably increased. This prospective study aimed to evaluate whether the use of birth weight (BW) or body surface measurements as a guide for proper depth estimation of the UVC insertion was more accurate. Patients and methods A total of 104 neonates were assigned to two groups according to procedure used for proper UVC depth insertion: shoulder–umbilicus length graphs versus BW-based formula. Radiological assessment of correct catheter tip position was determined in both groups. Results The overall success rate for UVC insertion was 96% (100/104). However, …


Once-Daily Versus Twice-Daily Enoxaparin For The Initial Treatment Of Acute Deep Venous Thrombosis: A Case–Control Study, Ahmed Samir, Asim M. Herz-Allah, Mohamad T. Yusuf, Mohamed M. Gouda, Mourad I. Alkhouly Jun 2019

Once-Daily Versus Twice-Daily Enoxaparin For The Initial Treatment Of Acute Deep Venous Thrombosis: A Case–Control Study, Ahmed Samir, Asim M. Herz-Allah, Mohamad T. Yusuf, Mohamed M. Gouda, Mourad I. Alkhouly

Journal of Medicine in Scientific Research

Background In the initial treatment of deep venous thrombosis (DVT), enoxaparin is administered twice daily. A once-daily treatment regimen is more convenient for the patients and may optimize home treatment. However, it is not clear whether a once-daily treatment regimen is as safe and effective as a twice-daily treatment regimen. Purpose Our objective is to assess and compare the efficacy (in terms of recurrent venous thromboembolism) and safety (i.e. major hemorrhagic events) of once-daily versus twice-daily administration of enoxaparin for the initial treatment of DVT. Patients and methods A case–control study was conducted. We studied the efficacy and safety of …


Vitamin D Level In Rheumatoid Arthritis And Its Correlation With The Disease Activity, Amany Fayez Hakim, Soha Sayed Shaaban Jun 2019

Vitamin D Level In Rheumatoid Arthritis And Its Correlation With The Disease Activity, Amany Fayez Hakim, Soha Sayed Shaaban

Journal of Medicine in Scientific Research

Objective Vitamin D has an immunomodulatory and anti-inflammatory action, and its deficiency may cause several autoimmune disorders, including rheumatoid arthritis (RA). The relationship between vitamin D level and the severity of RA is of mere interest to several researchers. Patients and methods This prospective study included 40 cases of RA and 20 healthy controls, of age group between 40–70 years. Serum Vitamin D levels were measured and compared in RA patients and controls. Vitamin D levels in RA patients were measured in three different groups; active RA group, inactive RA group and control. Results Sixty-five percent patients of active RA …