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Articles 721 - 750 of 2151
Full-Text Articles in Medical Specialties
Addenda Vol. 29, No. 2, 1981
Henry Ford Hospital Medical Journal
No abstract provided.
Intractable Hiccups And A Posterior Fossa Arteriovenous Malformation: A Case Report, Timothy J. Laing, Mircea A. Morariu, Ghaus M. Malik, Suresh C. Patel
Intractable Hiccups And A Posterior Fossa Arteriovenous Malformation: A Case Report, Timothy J. Laing, Mircea A. Morariu, Ghaus M. Malik, Suresh C. Patel
Henry Ford Hospital Medical Journal
A 29-year-old man is presented who developed intractable hiccups following a subarachnoid hemorrhage from a posterior fossa dural arteriovenous malformation (AVM). The hiccups persisted even after various treatments had been attempted, and the AVM had been excised surgically. The hiccups stopped after a bilateral phrenic nerve section was performed. This report reviews the central causes and mechanisms of hiccups and emphasizes the importance of selective vertebral angiography in demonstrating posterior fossa AVM.
Vertebral Artery Injury: Case Report And Review Of Operative Approaches, Richard G. Stapleford, James C. Gruenberg, D. Gary Wolford, James B. Kerchner
Vertebral Artery Injury: Case Report And Review Of Operative Approaches, Richard G. Stapleford, James C. Gruenberg, D. Gary Wolford, James B. Kerchner
Henry Ford Hospital Medical Journal
Traumatic injury to the upper third of the neck, cephalad to the angle of the mandible, distorts the complexity of normal anatomy and underscores the importance of preoperative arteriography when possible. This report describes the case of a young man who was brought to the Emergency Room of our hospital suffering from a severe gunshot wound to the cervical spine, vertebral artery, and maxillofacial skeleton. His injury was successfully managed by combining a standard arterolateral incision with a procedure that has been described for exposing retro maxillary tumors. This operative technique provided the surgeon with direct access to the injury, …
The Polytetrafluoroethylene (Ptfe) Graft For Portacaval Interposition: An Experimental Observation, Alexander G. Yap, George Isshak, Ronald Lam, Roger F. Smith
The Polytetrafluoroethylene (Ptfe) Graft For Portacaval Interposition: An Experimental Observation, Alexander G. Yap, George Isshak, Ronald Lam, Roger F. Smith
Henry Ford Hospital Medical Journal
In an attempt to determine the efficacy of the polytetrafluoroethylene (PTFE) graft as a portacaval interposition shunt, 26 mongrel dogs were randomly selected to receive a side-to-side shunt with a 6 mm, 8 mm, or 10 mm PTFE graft after portal hypertension had been created by hepatic vein ligation. The dogs were clinically observed, and if they showed signs of graft occlusion, they were reexplored surgically. The 6 mm graft had a 0% patency rate; the 8 mm graft had a 28.6% patency rate; and the 10 mm graft had an 87.5% patency rate. Histological examinations revealed adequate incorporation of …
A New Surgical Approach To Stabilizing C1-2 Subluxation In Rheumatoid Arthritis, R. A. De Los Reyes, G. M. Malik, K. K. Wu, J. I. Ausman
A New Surgical Approach To Stabilizing C1-2 Subluxation In Rheumatoid Arthritis, R. A. De Los Reyes, G. M. Malik, K. K. Wu, J. I. Ausman
Henry Ford Hospital Medical Journal
Atlanto-axial subluxation in patients with rheumatoid arthritis presents a difficult therapeutic problem. Because of their underlying disease, these patients do not tolerate the heavy orthotic devices or prolonged periods of immobilization associated with traditional methods of surgical fusion. This paper describes a surgical technique which allows early mobilization and minimal external fixation. The results from a series of ten patients in which this technique was used are also discussed.
A Role For Dentistry In Managing The Oro-Nasopharyngeal Irradiated Cancer Patient, Michael R. Britt
A Role For Dentistry In Managing The Oro-Nasopharyngeal Irradiated Cancer Patient, Michael R. Britt
Henry Ford Hospital Medical Journal
Radiation therapy for oral and nasopharyngeal carcinoma produces direct and indirect changes in the oral cavity. Before such therapy is begun, the cancer patient should be examined by a trained dental specialist so that associated problems such as oral mucositis, xerostomia, radiation dental caries, osteoradionecrosis, and ageusia can be addressed. During and after irradiation therapy as well, the dental specialist should be involved in the treatment program. In this way, it Is possible to maintain the patient's dental system through restorative measures, mandatory use of topical fluorides, dental rinses, and preventive prophylaxis.
Henry Ford Hospital Clinicopathological Conference: Encephalopathy And Renal Failure In A Three-Month-Old Infant
Henry Ford Hospital Medical Journal
No abstract provided.
Behcet's Syndrome: Case Report And Literature Review, K. V. Venkatasubramaniam, Douglas R. Swinehart
Behcet's Syndrome: Case Report And Literature Review, K. V. Venkatasubramaniam, Douglas R. Swinehart
Henry Ford Hospital Medical Journal
Behcet's syndrome is a disease commonly found in Japan and in countries around the Mediterranean Sea. In the U.S., it is relatively uncommon. This report describes a 24-year-old Lebanese-American man with Behcet's syndrome who presented with symptoms four months after he developed arthritis and who had been initially diagnosed as having incomplete Reiter's syndrome. A literature review is Included.
The Role Of Industry In The Development Of Biomedical Technology, Raymond H. Kahn
The Role Of Industry In The Development Of Biomedical Technology, Raymond H. Kahn
Henry Ford Hospital Medical Journal
The world is undergoing a biological revolution that has made unparalleled demands on the American health care system. This demand for health care and its escalating costs provide abundant Incentives for reducing the cost through better technology. Recent developments in medical technology include the CAT scanner, nuclear magnetic resonance (NMR), as well as new advances in prosthetic devices. Most biomedical research and development takes place at not-for-profit institutions, such as universities, hospitals, and private foundations, much of it supported by federal funding from such sources as the National Institutes of Health. But, today, the institutions are in danger of major …
The Epidural Defect On Myelography: Some Unusual Causes, Keenan L. Carroll
The Epidural Defect On Myelography: Some Unusual Causes, Keenan L. Carroll
Henry Ford Hospital Medical Journal
This report describes four cases of epidural defect found on myelography that illustrate some unusual causes of this defect. These include a type I chondrosarcoma, primary hemangioendothelioma, hematoma, and an epidural abscess. Surgery was performed, and all four patients have recovered with little or no remaining neurological deficit. If there is anything unusual about the epidural defect or if the clinical findings do not agree with the radiographic films, the radiologist should be alert for other, less common causes of the defect.
Second-Year Follow-Up Study On Systematic Treatment Of Chronic Pain With Antidepressants, Dietrich Blumer, Mary Heilbronn
Second-Year Follow-Up Study On Systematic Treatment Of Chronic Pain With Antidepressants, Dietrich Blumer, Mary Heilbronn
Henry Ford Hospital Medical Journal
Systematic therapy with antidepressant drugs can be an effective treatment for chronic pain patients with the pain-prone disorder. This survey follows the pain status, medications, depressive symptoms, work status, and treatment of 104 patients treated for chronic pain at Henry Ford Hospital's Pain Clinic during a two-year period for chronic pain in the absence of a significant somatic disorder. No patients were excluded from treatment and the dropout rate of 64% after two years was not surprising. The pain of those who complied with therapy improved significantly (62%), compared to that of the patients who had dropped out of the …
Combining Provocative Agents Of Calcitonin To Detect Medullary Carcinoma Of The Thyroid, J. C. Sisson, M. D. Gross, J. E. Frietas, C. E. Jackson, B. G. England
Combining Provocative Agents Of Calcitonin To Detect Medullary Carcinoma Of The Thyroid, J. C. Sisson, M. D. Gross, J. E. Frietas, C. E. Jackson, B. G. England
Henry Ford Hospital Medical Journal
The presence of clinically undetectable medullary thyroid cancer can be revealed by characterisdc patterns of calcitonin in serum after the injection of a provocative agent, pentagastrin or calcium ion. However, in some reports, medullary thyroid cancer was uncovered in a test with pentagastrin but not in one with calcium ion, and vice versa. To reduce the number of erroneous responses, each provocative agent has been employed in separate tests. Combining pentagastrin and calcium into one stimulus should give the advantage of each agent while requiring less time and fewer analyses in a single test. We combined pentagastrin injection and calcium …
1980 Publications Of The Staff Of Henry Ford Hospital
1980 Publications Of The Staff Of Henry Ford Hospital
Henry Ford Hospital Medical Journal
No abstract provided.
Henry Ford Hospital: Options And Opportunities In The 1980s, Douglas S. Peters, Bruce W. Steinhauer
Henry Ford Hospital: Options And Opportunities In The 1980s, Douglas S. Peters, Bruce W. Steinhauer
Henry Ford Hospital Medical Journal
This presentation by Mr. Peters and Dr. Steinhauer was given before the Henry Ford Hospital Professional Staff at a semi-annual dinner and staff meeting held on Tuesday, May 6, 1980. It offers a timely assessment of the position and prospects of the Hospital as we enter the new decade. On occasion, the journal features nontechnical articles like this presentation that we believe are of general interest to our readers.
Surgical Management Of Multicentricity, Nipple-Areola Involvement, And Bilaterality In Breast Carcinoma, F. Samhouri, M. Block, A. Kambouris
Surgical Management Of Multicentricity, Nipple-Areola Involvement, And Bilaterality In Breast Carcinoma, F. Samhouri, M. Block, A. Kambouris
Henry Ford Hospital Medical Journal
During a five-year period, 457 women who underwent partial, segmental, or total mastectomy were assessed for multicentricity (31%), nipple-areola involvement (17%), and bilateral breast carcinoma (9%). These factors determined the extent of surgery performed and the possibilities for later breast reconstruction. The frequency of nipple-areola involvement in breast cancer strongly indicates the need for alternatives to their preservation for breast reconstruction. The study concludes that total mastectomy for invasive carcinoma is the preferred method of treatment for early breast cancer until further clinical trials have assessed the value of segmentectomy.
Preliminary Experience With Endoscopic Papillotomy, Bernard Schuman
Preliminary Experience With Endoscopic Papillotomy, Bernard Schuman
Henry Ford Hospital Medical Journal
Endoscopic papillotomy is a non-operadve technique used to manage choledocholithiasis and papillary stenosis. Considerable experience in Europe and initial results in a few medical centers in the United States indicate that it is effective and safe. Six papillotomy procedures were performed at Henry Ford Hospital without complication, and with a successful outcome in five. Endoscopic papillotomy is the procedure of choice for retained common bile duct stones less than 2 cm in diameter.
Acute And Massive Intraparenchymal Hemorrhages Of The Posterior Fossa, Dennis E. Wilkins
Acute And Massive Intraparenchymal Hemorrhages Of The Posterior Fossa, Dennis E. Wilkins
Henry Ford Hospital Medical Journal
Acute, massive cerebellar and pontine hemorrhages are discussed in the context of the routine availability of cranial computerized tomography. The diagnosis of these disorders is emphasized. An updated clinical review of the edologic, pathogenetic, and therapeutic aspects is also presented, with particular attention to the importance of hypertensive cerebrovascular disease as the most common underlying disorder.
Prenatal Diagnosis Of Fetal Cystic Hygromas Associated With Generalized Lymphangiectasis, Chang Y. Lee, Beatrice L. Madrazo, Daniel L. Van Dyke, Jewel Smith
Prenatal Diagnosis Of Fetal Cystic Hygromas Associated With Generalized Lymphangiectasis, Chang Y. Lee, Beatrice L. Madrazo, Daniel L. Van Dyke, Jewel Smith
Henry Ford Hospital Medical Journal
Ultrasonography has made possible the prenatal diagnosis of many congenital fetal abnormalities. This report describes two cases of bilateral cystic hygromas of the neck associated with generalized lymphangiectasis that were diagnosed by ultrasound. Ultrasonic scans revealed moderate polyhydramnios: thick, edematous placenta and edematous fetus with large cystic mass occupying both sides of the neck and extending to the upper chest wall, ascites, and pleural effusion at gestational ages of 21.5 and 24 weeks, respectively. In one case, chromosomal study from amniotic fluid cell culture revealed X chromosome monosomy, often associated with lymphatic anomalies. The prenatal diagnosis was confirmed at birth: …
Dysfunction Of Mitral Ball Valve Prosthesis, M. R. S. Nair, Wolf F. C. Duvernoy, Daniel T. Anbe, Eldred G. Zobl, Agustin Arbulu
Dysfunction Of Mitral Ball Valve Prosthesis, M. R. S. Nair, Wolf F. C. Duvernoy, Daniel T. Anbe, Eldred G. Zobl, Agustin Arbulu
Henry Ford Hospital Medical Journal
Three case histories of patients with malfunctions of Smeloff-Cutter mitral ball valve prostheses are presented here - one underwent successful replacement. The clinical diagnosis was made by observing a marked variation in the A2OC interval and intermittent absence of the opening click. Phonocardiograms were diagnostic in all three cases. while echocardiograms and even angiograms did not uniformly diagnose prosthetic valve dysfunction. Periodic phonocardiographic evaluations may be helpful in early detection of the prosthetic valve dysfunction. Once the diagnosis is established, immediate surgical treatment is imperative to prevent sudden death.
Clinical Thermoradiotherapy, H. I. Bicher, T. S. Sandhu, F. W. Hetzel
Clinical Thermoradiotherapy, H. I. Bicher, T. S. Sandhu, F. W. Hetzel
Henry Ford Hospital Medical Journal
A clinical trial is currently in progress to determine the efficacy of combined fractions of hyperthermia and radiation. The protocol consists of two parts. First, four fractions of microwave-induced hyperthermia (45.0° ± 0.5°C) are applied for 1 1/2 hours to the volume encompassing the tumor, each separated by 72 hours. After a one-week rest, a second series of four fractions is administered again at 72- hour intervals. Each fraction consists of a 400 rad dose of radiation followed within 20 minutes by hyperthermia (42.5 ± 0.5°C) for 1 1/2 hours. Currently, we have treated 62 patients with 82 fields with …
Clinical Hyperthermia And Irradiation: Pilot Studies, John Fazekas, Ted Nerlinger
Clinical Hyperthermia And Irradiation: Pilot Studies, John Fazekas, Ted Nerlinger
Henry Ford Hospital Medical Journal
Phase / (February 1979-May 1980) of our hyperthermia pilot study involved 26 carcinoma patients who participated in two treatment protocols: 20 patients received electron beam x-ray therapy plus an average of eight hyperthermia sessions (twice weekly at 42.5°-43.5°C intralesional temperatures for 40 minutes); 17 patients were heated with a 3450 microwave MHz generator in conjunction with surface heating (circulating water bag at 45°C). AGA thermograms assessed superficial blood flow to document heating patterns and forewarned of potential overheating as manifested by superficial burns (blisters). Although our study Is nonrandomized and our patient numbers are small, we noted a complete response …
Local Hyperthermia And Radiation: A Biologically-Oriented Clinical Scheduling, G. Arcangeli, A. Cividalli
Local Hyperthermia And Radiation: A Biologically-Oriented Clinical Scheduling, G. Arcangeli, A. Cividalli
Henry Ford Hospital Medical Journal
In a series of animal tumor studies, heat was directly delivered into the tumor mass with an interstitial applicator. After hyperthermia (44°-45°C for 45 minutes) or radiation alone (3x10 Gy), only a slight delay in tumor growth was observed, while the combined treatment, either simultaneous or sequential (i.e., heat delivered four hours after irradiation), appeared to be the most effective. The cure rate in the two combined treatment groups was 100%, in contrast to the lack of cure in the first two groups. The simultaneous use of heat and x-ray appeared to be slightly more effective than the sequential schedule; …
Glucose Metabolism In Mouse Tumor And Liver With And Without Hyperthermia, Christian Streffer, Siegelinde Hengstebeck, Peter Tamulevicius
Glucose Metabolism In Mouse Tumor And Liver With And Without Hyperthermia, Christian Streffer, Siegelinde Hengstebeck, Peter Tamulevicius
Henry Ford Hospital Medical Journal
We measured levels of glycolytic metabolites in mouse tumor and liver after administering a glucose load of 6 mg/g of body weight and after hyperthermia for one hour at 43°C. Metabolites included glucose, glucose-6-phosphate, fructose-1.6-diphosphate, dihydroxyacetone-phosphate, glycerol-3-phosphate, pyruvate, and lactate, as well as acetoacetate and β-hydroxybutyrate. The combined treatment led to an increase of the lactate level and apparently enhanced glucose degradation. The redoxequilibria states were shifted to the reduced metabolites. It is possible that hypoxia was induced or enhanced, which could have significance for tumor therapy. At later periods after hyperthermia, metabolic alterations occurred that have also been observed …
Hyperthermia, F. K. Storm
Hyperthermia, F. K. Storm
Henry Ford Hospital Medical Journal
This report describes the history of hyperthermia and reviews current forms of treatment at both low (42°-43°C) and higher (<45°C) temperatures. Hyperthermia treatment at low temperatures includes fluid immersion and irrigation, regional perfusion with heated fluids, and electromagnetic radiofrequency waves. Low-temperature hyperthermia has also been combined with radiation therapy and with chemotherapy in recent clinical trials. At higher temperatures, we and other investigators have also had promising, preliminary results in treating tumors safely. With the specialized radiofrequency instrumentation we have developed to apply hyperthermia at any depth without preferential surface tissue heating, further clinical investigation of both superficial and deep internal solid tumors is now possible. Recent data suggest that hyperthermia may be an especially effective form of therapy for larger tumors that resist standard forms of treatment. Clinical trials are now underway to determine the most therapeutic dose/time regimen, to determine toxicity and therapeutic enhancement ratios of combined chemotherapy and x-irradiation with hyperthermia, and to evaluate any changes in the host immune system with such therapies.
Hyperthermic Perfusion 16 Years After Its First Clinical Applications, R. Cavaliere, G. Moricca, F. Di Filippo, L. Aloe, G. Monticelli, F. S. Sartori
Hyperthermic Perfusion 16 Years After Its First Clinical Applications, R. Cavaliere, G. Moricca, F. Di Filippo, L. Aloe, G. Monticelli, F. S. Sartori
Henry Ford Hospital Medical Journal
It is known that above-normal temperatures (42°-42.5°C) provoke selective damage to neoplastic cells. We used heated circulating blood as a method for heat transfer on patients with limb tumors. From October 1964 to December 1979, we treated a total of 198 patients with hyperthermic perfusion for melanoma of the limbs (91), osteosarcoma (57), and soft tissue sarcoma (50). For melanoma patients, the five-year survival rate, excluding Stage IV, was 60%. For patients with soft tissue sarcoma, the five-year survival rates were 53% and 56% for hyperthermic perfusion and hyperthermic antiblastic perfusion. respectively. For 29 patients with osteosarcoma, hyperthermic perfusion was …