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Articles 691 - 720 of 2151
Full-Text Articles in Medical Specialties
Familial Hypokalemic Periodic Paralysis In Blacks, Jack M. Bernstein, Michael Kleerekoper
Familial Hypokalemic Periodic Paralysis In Blacks, Jack M. Bernstein, Michael Kleerekoper
Henry Ford Hospital Medical Journal
Hypokalemic periodic paralysis is an uncommon disease that has rarely been reported in blacks. Historical, clinical, and pathological findings in three black patients, in addition to those previously reported in the literature, suggest that the spectrum of the disease is identical in both blacks and whites. Considering the disease as either different or unknown in the black population is probably not justified.
Chronic Idiopathic Thrombocytopenic Purpura: Effective Preoperative Preparation And Long-Term Results Of Splenectomy, James C. Gruenberg, Melvin A. Block, Ellis J. Van Slyck, Joseph P. Abraham
Chronic Idiopathic Thrombocytopenic Purpura: Effective Preoperative Preparation And Long-Term Results Of Splenectomy, James C. Gruenberg, Melvin A. Block, Ellis J. Van Slyck, Joseph P. Abraham
Henry Ford Hospital Medical Journal
A retrospective review of 98 patients seen at Henry Ford Hospital from 1953 through 1977 demonstrated that splenectomy for chronic idiopathic thrombocytopenic purpura provided a good response which usually was sustained on long-term follow-up (72% at 15 years). Although splenectomy for this condition had a low mortality, morbidity was significant in patients older than 40 years. When compared to patients whose response to splenectomy was sustained, patients who relapsed had significantly lower platelet counts preoperatively both when they were untreated (mean: 9,194 per cc versus 18,524 per-cc) and/or when they were treated with steroids (mean: 85,647 per cc versus 142,590 …
Effect Of Levamisole On The Incidence Of Spontaneous Mammary Tumors In C3h Mice, Robert H. Page, Duilio A. Valdivia, Robert W. Talley, Robert A. Huseby
Effect Of Levamisole On The Incidence Of Spontaneous Mammary Tumors In C3h Mice, Robert H. Page, Duilio A. Valdivia, Robert W. Talley, Robert A. Huseby
Henry Ford Hospital Medical Journal
Spontaneous mammary carcinoma in C3H mice is preceded by premalignant hyperplastic alveolar nodules. When a primary tumor is evident, examination of the other mammae will reveal a number of microscopic precancerous lesions in various stages of transformation to overt malignant tumors. In an effort to inhibit the development of additional malignant tumors after surgical removal of the first apparent tumor, we treated female C3H/HeJ mice with subcutaneous injections of levamisole (0.6 mg per kg of body weight) on a twice weekly regimen. All further tumors were surgically excised when they became palpable. The surgical excision of bulk tumor burden, immunorestoration …
Acid Phosphatase: Clinical Utility Of The First Tumor Marker, Christopher J. Dipaolo, Jan Rival
Acid Phosphatase: Clinical Utility Of The First Tumor Marker, Christopher J. Dipaolo, Jan Rival
Henry Ford Hospital Medical Journal
Acid phosphatase was the first tumor marker to be measured in blood. Although it is used as a marker of prostatic carcinoma, serum levels are also elevated in many diseases of prostate, bone, and hematologic tissue. While serum acid phosphatase concentration is elevated in patients with prostatic carcinoma or infarction, it may also be increased merely with benign hypertrophy and after prostate massage. Recent studies demonstrate that levels are not significantly increased after routine rectal examination. Although of limited use as a screening test, the assay may be useful in staging, prognostication during hormonal therapy, and in making clinical decisions. …
The Central Surgical Association Turns Forty: Some Highlights Of The First Twenty Years, Conrad R. Lam
The Central Surgical Association Turns Forty: Some Highlights Of The First Twenty Years, Conrad R. Lam
Henry Ford Hospital Medical Journal
The Central Surgical Association assembled for the first time in Detroit and Ann Arbor, Michigan in February, 1941. On the 40th anniversary of this meeting, the Association met again in the same geographical region, in Dearborn. Selected papers from the first twenty years have been chosen as highlights. Criteria for choosing a few from many significant papers were the originality of the material, its time-proven value, and the subsequent impressive careers of the authors. Appropriate credit is given to Dr. Roy D. McClure for his concept of an organizadon of surgeons in the central geographical area and for his efficient …
Compression Of The Duodenum By The Root Of The Mesentery, Peter A. Haas, Jawaid Akhtar, Lester Kobylak
Compression Of The Duodenum By The Root Of The Mesentery, Peter A. Haas, Jawaid Akhtar, Lester Kobylak
Henry Ford Hospital Medical Journal
Compression of the duodenum by the root of the mesentery is a rare pathological entity that has caused much controversy because it has been mistakenly identified as the "superior mesenteric artery syndrome" or the "vascular compression of the duodenum." We discuss the pathological anatomy and the diagnosis of the disease, and report an illustrative case. Some authors report many cases of the syndrome, while others doubt its existence. Before surgery is considered, the diagnosis should be established beyond doubt and a prolonged period of observation, medical treatment, and nutritional support should be provided. The barium contrast swallowing test combined with …
Rupture Of Mycotic Aneurysm During Pregnancy: Another Hazard Of Drug Abuse, Jayanta Kumar Dirghangi, Mohammed R. Ansari
Rupture Of Mycotic Aneurysm During Pregnancy: Another Hazard Of Drug Abuse, Jayanta Kumar Dirghangi, Mohammed R. Ansari
Henry Ford Hospital Medical Journal
Widespread parenteral drug abuse has led to an increase in mycotic aneurysms in the area of drug injection. We report an unusual case of ruptured mycotic aneurysm of the right external iliac artery in a pregnant woman who was a heroin addict. In the third trimester, she developed a large hematoma that resulted in intra-uterine fetal death, premature labor, and hypovolemic shock. This case presented a difficult diagnostic and therapeutic dilemma that was confused with the syndrome of ruptured utero-ovarian veins.
Editorials, Raymond H. Kahn, Michael Kleerekoper, Irwin K. Rosenberg
Editorials, Raymond H. Kahn, Michael Kleerekoper, Irwin K. Rosenberg
Henry Ford Hospital Medical Journal
No abstract provided.
The Immunology Of Inflammatory Bowel Disease, Hugh L. N. Mackechnie
The Immunology Of Inflammatory Bowel Disease, Hugh L. N. Mackechnie
Henry Ford Hospital Medical Journal
Although several measurements of both cellular and humoral immunity are altered in inflammatory bowel disease (IBD), no direct pathogenic role can be confirmed in either ulcerative colitis (UC) or Crohn's disease (CD). No clear role has been shown for allergic, microbiological, or psychogenic factors, and no specific genetic susceptibility has been demonstrated. Several studies have shown some benefit from using immunosuppressive drugs to treat inflammatory bowel disease, such as sulfasalazine to treat ulcerative colitis and corticosteroids to treat Crohn's disease. Whether these benefits derive from the anti-inflammatory activity of these drugs or from their immunological effects is uncertain.
Acute Burkitt's Leukemia: Case Report And Literature Review, S. Raman, S. M. Saeed, K. R. Kini
Acute Burkitt's Leukemia: Case Report And Literature Review, S. Raman, S. M. Saeed, K. R. Kini
Henry Ford Hospital Medical Journal
The occurrence of leukemia in Burkitt's lymphoma, with or without visceral or nodal tumefaction is uncommon, and its initial presentation as leukemia is even more unusual. Because it has a poor chemotherapeutic response and a grave prognosis, it is important to recognize this unusual leukemia correctly. Our report describes the clinical and pathologic findings of Burkitt's lymphoma cell leukemia in a five-year-old white boy who presented with abdominal distension, hepatosplenomegaly, and lymphadenopathy. Blood examination revealed normocytic normochromic anemia, erythroblastosis, slight leukocytosis, and the presence of numerous (24%) blasts. A diagnosis of Burkitt's lymphoma was established on the basis of morphologic, …
Zoonoses In Modern Medical Practice, Tom Madhavan
Zoonoses In Modern Medical Practice, Tom Madhavan
Henry Ford Hospital Medical Journal
Zoonoses are infections transmitted by animals to man. Of the more than 50 such infections that are clinically significant, several are discussed in the articles by McIntosh and Madhavan and by Meyer and Adar in this issue of the Journal (pp. 7-13). These include brucellosis, leptospirosis, relapsing fever, Colorado tick fever, toxoplasmosis, psittacosis, and echinococcosis. The McIntosh and Madhavan article reviews the experience at Henry Ford Hospital with 60 patients, while the article by Meyer and Adar reports on an unusual case of echinococcosis of the spine and retroperitoneum that occurred at Haim Sheba Medical Center in Israel.
Zoonoses At Henry Ford Hospital: Clinical, Epidemiologic, And Therapeutic Aspects, Nancy Mcintosh, Tom Madhavan
Zoonoses At Henry Ford Hospital: Clinical, Epidemiologic, And Therapeutic Aspects, Nancy Mcintosh, Tom Madhavan
Henry Ford Hospital Medical Journal
Zoonoses are diseases of animals that can be transmitted to humans. We reviewed the experience with zoonotic illnesses treated at Henry Ford Hospital in the past ten years. Included in this report are cases of brucellosis, leptospirosis, relapsing fever, Colorado tick fever, toxoplasmosis, psittacosis, and pasteurellosis. This report describes the clinical and epidemiologic aspects of zoonoses in 60 patients in a large urban general hospital.
Echinococcosis Of The Spine And Retroperitoneum: Case Report And Review Of The Literature, Eugene Meyer, Raphael Adar
Echinococcosis Of The Spine And Retroperitoneum: Case Report And Review Of The Literature, Eugene Meyer, Raphael Adar
Henry Ford Hospital Medical Journal
Echinococcosis is a zoonosis transmitted from sheep dogs to humans. It occurs most frequently in sheep and cattle-raising countries, and children who come in contact with sheep dogs are the most likely victims. The liver and the lungs are the most common sites of the hydatid cysts. Their presence in other organs is less common, and primary hydatidosis of the retroperitoneum is extremely rare. In the case reported here, a 65-year-old man had secondary retroperitoneal echinococcosis that recurred three times in 23 years. On the third occasion, marsupialization was performed on a large cyst found in the right retroperitoneum.
Racial Differences In The Incidence Of Steroid Diabetes In Renal Transplant Patients, Francis Dumler, Hajime Hayashi, Jay Hunter, Nathan W. Levin
Racial Differences In The Incidence Of Steroid Diabetes In Renal Transplant Patients, Francis Dumler, Hajime Hayashi, Jay Hunter, Nathan W. Levin
Henry Ford Hospital Medical Journal
We have studied the development of steroid-induced diabetes in a population of 143 renal allograft recipients who were nondiabetic before transplantation. Steroid-induced diabetes developed In 9.8% of patients. However, in blacks its incidence was significantly higher than in whites (17.3% vs 5.5% respectively; p < .01). The development of steroid-induced diabetes was not associated with a higher frequency of HLA-B8 or HLA-Bw15 in either race. In black graft recipients, HLA-B14 was significantly more frequent (p < .001) among those who developed steroid-induced diabetes than in insulin-dependent diabetic (Type I) and nondiabetic recipients. The clinical course of patients with steroid-induced diabetes has been similar to that of noninsulin-dependent diabetics (Type II).
Cytopathology Of Thyroid Nodules, Sudha R. Kini, J. Martin Miller, Joel I. Hamburger
Cytopathology Of Thyroid Nodules, Sudha R. Kini, J. Martin Miller, Joel I. Hamburger
Henry Ford Hospital Medical Journal
Fine needle aspiradon biopsy is a simple and accurate means of obtaining a tissue diagnosis for a thyroid nodule. Our experience with 3,000 such biopsies and 242 surgically proven cancers has enabled us to characterize the cytologic presentations of the common "nodular" thyroid diseases. We can readily identify nodular goiter and papillary, poorly differentiated follicular, medullary, anaplastic, and metastatic cancers. Benign follicular neoplasms and well-differentiated follicular cancers cannot be separated with great accuracy, but useful predictions can be made. Care is required to recognize the cellular abnormalities of autoimmune thyroiditis and to diagnose the coexistence of this disease with malignant …
The Facioscapulohumeral Syndrome: A Report Of Two Cases, J. Kaner, J. Zuniga, Robert D. Teasdall
The Facioscapulohumeral Syndrome: A Report Of Two Cases, J. Kaner, J. Zuniga, Robert D. Teasdall
Henry Ford Hospital Medical Journal
Two patients developed progressive muscle weakness in adult life. The initial diagnosis of polymyositis was made in both cases, but subsequent studies and the distribution of muscle involvement suggested facioscapulohumeral myopathy. Other investigators have proposed that this syndrome may result from either genetic or acquired causes. In our patients, the disorder was probably a sequela of polymyositis.
Editorials, Raymond C. Mellinger, Stanley R. Nelson, Fred W. Whitehouse
Editorials, Raymond C. Mellinger, Stanley R. Nelson, Fred W. Whitehouse
Henry Ford Hospital Medical Journal
No abstract provided.
Combined Heat And X-Ray Treatment Of Experimental Tumours, J. Denekamp, S. A. Hill, F. A. Stewart
Combined Heat And X-Ray Treatment Of Experimental Tumours, J. Denekamp, S. A. Hill, F. A. Stewart
Henry Ford Hospital Medical Journal
No abstract provided.
Clinical Thermoradiotherapy, H. I. Bicher, T. S. Sandhu, F. W. Hetzel
Clinical Thermoradiotherapy, H. I. Bicher, T. S. Sandhu, F. W. Hetzel
Henry Ford Hospital Medical Journal
No abstract provided.
Clinical Hyperthermia Pilot Studies, Thomas Jefferson University Hospital: Results Of 42.5c. Adjuvant To Irradiation, John Fazekas, Ted Nerlinger
Clinical Hyperthermia Pilot Studies, Thomas Jefferson University Hospital: Results Of 42.5c. Adjuvant To Irradiation, John Fazekas, Ted Nerlinger
Henry Ford Hospital Medical Journal
No abstract provided.
An Updated Analysis Of Microwave Hyperthermia At 2450 Megahertz And 915 Megahertz Frequencies, Kenneth H. Luk
An Updated Analysis Of Microwave Hyperthermia At 2450 Megahertz And 915 Megahertz Frequencies, Kenneth H. Luk
Henry Ford Hospital Medical Journal
No abstract provided.
Glucose Metabolism In Liver And An Adenocarcinoma Of Mice With And Without Hyperthermia, Christian Streffer, Sieglinde Hegstebeck, Peter Tamulevicius
Glucose Metabolism In Liver And An Adenocarcinoma Of Mice With And Without Hyperthermia, Christian Streffer, Sieglinde Hegstebeck, Peter Tamulevicius
Henry Ford Hospital Medical Journal
No abstract provided.
Hyperthermia, F. K. Storm
Local Microwave Hyperthermia In Cancer Therapy. Preliminary Report, Carlos A. Perez, Walter Kopecky, Robert Baglan, D. Venkata Rao, Richard Johnson
Local Microwave Hyperthermia In Cancer Therapy. Preliminary Report, Carlos A. Perez, Walter Kopecky, Robert Baglan, D. Venkata Rao, Richard Johnson
Henry Ford Hospital Medical Journal
No abstract provided.