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Hemorrhagic Corpus Luteum Mimicking Heterotopic Pregnancy, Saba Sohail

Department of Radiology

Hemorrhagic corpus luteum (CL) is clinically known to simulate a number of medical, surgical and gynecologic conditions that cause acute abdomen. One such case is hereby presented that mimicked ectopic pregnancy clinically and heterotopic pregnancy on ultrasound. Laparoscopy was decisive.

Quantitative 1h Magnetic Resonance Spectroscopic Imaging Determines Therapeutic Immunization Efficacy In An Animal Model Of Parkinson's Disease., Michael D. Boska, Travis B. Lewis, Christopher J. Destache, Eric J. Benner, Jay A. Nelson, Mariano Uberti, R. Lee Mosley, Howard Gendelman

Journal Articles: Radiology

Nigrostriatal degeneration, the pathological hallmark of Parkinson's disease (PD), is mirrored by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication. MPTP-treated animals show the common behavioral, motor, and pathological features of human disease. We demonstrated previously that adoptive transfer of Copaxone (Cop-1) immune cells protected the nigrostriatal dopaminergic pathway in MPTP-intoxicated mice. Herein, we evaluated this protection by quantitative proton magnetic resonance spectroscopic imaging (1H MRSI). 1H MRSI performed in MPTP-treated mice demonstrated that N-acetyl aspartate (NAA) was significantly diminished in the substantia nigra pars compacta (SNpc) and striatum, regions most affected in human disease. When the same regions were coregistered with immunohistochemical stains for …

Multiple Parameters In The Diagnosis Of Ectopic Pregnancy, Iram Naseem, Vaqar Bari, Naila Nadeem

Department of Radiology

Objective: To determine the role of emergency ultrasound examination in the diagnosis and management of ectopic pregnancy.Methods: A descriptive study done at the Radiology Department, Aga Khan University Hospital, Karachi from January 1999 to December 2000 using observational facts by non-probability convenient sampling method. Seventy one patients who presented with acute symptoms in early pregnancy, were subjected to emergency pelvic ultrasound. Both transabdominal and transvaginal ultrasound were done in 52 patients while in 19 patients only transabdominal ultrasound was performed. Serum Beta hCG levels, of all patients were greater than 1500 iu/ml.Results: Ultrasound correctly identified ectopic pregnancy in 71 patients. …

Re-Emphasizing The Publication Ethics, Saba Sohail, Jamshed Akhtar

Department of Radiology

No abstract provided.

Clinics In Diagnostic Imaging (102), M Azeemuddin, T Ul-Haq, H Ahsan, W A. Memon

Department of Radiology

A 19-year-old man presented with cough and haemoptysis of ten days duration. He also had mild right hypochondrial pain. Chest radiograph and computed tomography (CT) showed a rounded soft tissue density opacity with an air crescent sign. CT showed multiple cystic lesions in the liver with a daughter cyst in its lateral wall. Diagnosis of hydatid disease of lung and liver was made. The contents of the liver cyst were aspirated, hypertonic saline instilled, re-aspirated, and absolute alcohol injected. Hydatid disease is endemic in certain parts of the world. Although the lungs and liver are most frequently affected, the disease …

Department Of Radiology-Annual Executive Summary Report-July 1, 2004 To June 30, 2005, Vijay M. Rao M.D.

Department of Radiology Administrative Documents and Reports

88 page Department of Radiology Annual Executive Summary Report, July 1, 2004 to June 30, 2005, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States.

Medium From Irradiated Cells Induces A Dose Dependent Expression Of Mitochondrial Changes And Bcl2 Responses In Unirradiated Human Keratinocytes, Paula Maguire, Carmel Mothersill, C. Seymour, Fiona Lyng

Articles

Exposure of unirradiated human keratinocytes to irradiated cell conditioned medium (ICCM) is known to cause a cascade of events that leads to reproductive death and apoptosis. This study investigates the effect of ICCM on clonogenic survival, mitochondrial mass and BCL2 expression in unirradiated keratinocytes. Exposure to 5 mGy, 0.5 Gy and 5 Gy ICCM resulted in a significant decrease in clonogenic survival. Human keratinocytes incubated with ICCM containing an antioxidant, N-acetylcysteine, showed no significant decrease in clonogenic survival. HPV-G cells incubated with ICCM containing a caspase 9 inhibitor showed no significant decrease in clonogenic survival when the ICCM dose was …

Manuscripts Categorization And Their Accreditation, Jamshed Akhtar, Saba Sohail

Department of Radiology

No abstract provided.

Cbct Panoramic Images Vs. Traditional Panoramic Radiographs, Sunny Young Hutchinson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this research was to compare the accuracy of angular measurements of the panoramic image of the Newtom 9000™ Cone Beam Computed Tomography (CBCT) with the Sirona™ Orthophos panoramic unit. The study was separated into three parts: phantom study, patient study, and archform study. The phantom study used fabricated phantom typodonts to compare angular measurements between the Newtom 9000™ panoramic image and the Sirona™ panoramic radiograph. Accuracies of the measurements were then determined by comparing the values to the actual phantom typodont. No marked differences in angular measurements were recorded for the phantom typodont using either of the …

Localization Of Upper Gi Bleed On Delayed Imaging With 99mtc Tagged Rbc Angiogram, M U. Zaman, R Hussain, Z Sajjad, M N. Ahmad

Department of Radiology

No abstract provided.

Prevalence Of Degenerative Joint Disease In A Pre-Orthodontic Adolescent Sample, Marie Mansour

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this research was to determine a prevalence of degenerative joint disease in our pre-orthodontic adolescent patients age ten through seventeen. The prevalence was assessed according to gender. Severity of DJD was established for each patient and a "red flag" for diagnosis was identified. The purpose was also to establish norms for joint space for patients with and without degenerative joint disease. Correlations to distal condyle position and angle classification were described. 123 consecutive patients, 77 female and 46 male T1 NewTom records were reviewed. Severity of DJD was classified according to none, mild, moderate, and severe. Sagittal …

Cone Beam Ct And Digital Radiography. A Comparative Study Of P/A Cephalometrics., Michael John Erickson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine if Rickett's posterio-anterior (P/A) cephalogram measurements could be obtained from Cone Beam Computerized Tomographic (CBCT) images taken on the NewTom QR-DVT 9000™.

Fifteen frontal cephalometric radiographs were chosen for good image quality, with no regard for patient age or gender. Each cephalogram was traced three times by the same operator using ZeroBase™ software. Landmarks were located and measured according to the Rickett's frontal analysis technique. Methods were devised for obtaining analogous measurements using CBCT images on the same group of patients.

Measurements obtained using CBCT correlated well with those obtained using the …

Managing Your Program With Shrinking Finances, Michael Hartman

Faculty Works: AHS (2004-2023)

Presented at Society of Diagnostic Medical Sonography Annual Conference, New Orleans, LA

This presentation is intended for sonology educators. The lecture will discuss various methods of cost effective course delivery, recruiting, and obtaining outside resources. Pitfalls and lessons learned will round out the presentation.

Transvaginal Sonography- Technique And Limitations, Saba Sohail

Department of Radiology

No abstract provided.

Percutaneous Embolisation And Transverse Myelitis: A Rare Association, O Ashraf, F Aslam, M Irfan, A B. Zubairi, M Azeemuddin

Department of Radiology

No abstract provided.

Ageing – The Independent Risk Indicator, Saba Sohail

Department of Radiology

No abstract provided.

Extradural Extramedullary Hematopoiesis: A Rare Mri Diagnosis With Atypical Features, M N. Ahmad, N Uddin, S Muzaffar, S N. Adil, Z Tasneem

Department of Radiology

No abstract provided.

The Evaluation Of Hepatocellular Carcinoma With Biphasic Contrast Enhanced Helical Ct Scan, J Yaqoob, V Bari, M U. Usman, K Munir, F Mosharaf, W Akhtar

Department of Radiology

Objective: To evaluate the role of biphasic contrast-enhanced helical CT including Hepatic Arterial Phase (HAP) imaging with Portal Venous Phase (PVP) imaging, in the detection and characterization of hepatocellular carcinomas.Methods: The study included 40 patients (M = 26, F = 14) with histopathologically proven HCC. Age range was between 30-85 years (mean = 55) by following consecutive patients with cirrhosis in whom Hepatocellular carcinoma was diagnosed or suspected either by raised serum a (alpha)-fetoprotein level or Ultrasound.Results: Biphasic contrast-enhanced examination revealed a total of 85 lesions in these 40 patients, out of which 13 were unifocal, 12 showed a dominant …

Transcatheter Chemo-Embolization For Hepatocellular Carcinoma And Certain Hepatic Metastasis, T U. Haq

Department of Radiology

No abstract provided.

The Role Of Magnetic Resonance Cholangiopancreatography (Mrcp) In Obstructive Jaundice, K Munir, V Bari, J Yaqoob, D B. Khan, M U. Usman

Department of Radiology

Objective: To evaluate the diagnostic value of MRCP in studying the sites and cause of obstructive jaundice in comparison with other imaging modalities at the Department of Radiology, Aga Khan University Hospital, from January 1999 to May 2001.Methods: Forty nine consecutive patients included 19 men and 30 women, suspected of obstructive jaundice. Patients underwent ultrasound (n = 49), CT (n = 11), ERCP (n = 25) and biliary surgery (n = 17). Final diagnosis was established by surgical exploration, endoscopic sphincterectomy, cytology and clinical follow up.Results: Of the 49 patients 17 had choledocholithiasis. Twenty five patients had malignant strictures, out …

Department Of Radiology-Annual Executive Summary Report-July 1, 2003 To June 30, 2004, Vijay M. Rao, M.D.

Department of Radiology Administrative Documents and Reports

85 page Department of Radiology Annual Executive Summary Report, July 1, 2003 to June 30, 2004, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States.

Oral Contrast-Enhanced Ct Cholangiography--An Initial Experience, I Naseem, J Rees

Department of Radiology

Objective: To describe our experience of CT (Computed tomographic) Cholangiography examination for detection of choledocholithiasis at the Aga Khan University Hospital (AKUH) Karachi Pakistan.Methods: Seven patients underwent helical CT cholangiography for suspected choledocholithiasis. Iopanoic acid (6 grams) was administered orally 8-12 hours before acquisition of a helical CT cholangiogram. Three-dimensional reconstructions and curved multiplanar reformations were generated from a set of axial source images.Results: Our patients had no adverse reactions to iopanoic acid. The degree of biliary opacification was sufficient to perform three-dimensional and curved planar reformations in 5 patients. In two patients, the biliary tree was not opacified. Both …

Ionizing Radiation Induces A Stress Response In Primary Cultures Of Rainbow Trout Skin, Fiona Lyng, M. Lyons-Alcantara, P. Owell, Sharon Ni Shuilleabhain, Colin Seymour, D. Cottell, Carmel Mothersill

Articles

Fish skin is very vulnerable to damage from physical and chemical pollutants because it is in direct contact with the aquatic environment. In this study, the effect of g radiation on primary cultures of rainbow trout skin was investigated. Primary cultures containing two cell types, epidermal cells and goblet mucous cells, were exposed to doses ranging from 0.5–15 Gy 60Co g radiation. Expression of PCNA, c-myc and BCL2 was investigated as well as growth and levels of apoptosis and necrosis. Morphological and functional changes were also studied. The irradiated cultures showed evidence of a dose-dependent increase in necrosis and enhanced …

Mammographic Criteria For Determining The Diagnostic Value Of Microcalcifications In The Detection Of Early Breast Cancer, M Yunus, N Ahmed, I Masroor, J Yaqoob

Department of Radiology

Objective: To evaluate the importance of microcalcifications in the detection of breast carcinoma in conventional mammography.Methods: This prospective study was carried out at Aga Khan University Hospital (AKUH). Mammograms of 68 patients with microcalcifications were evaluated. Craniocaudal and oblique views of both breasts were acquired on routine basis with cone compression and magnified views when required.Results: Among 68 patients with microcalcifications, 61 (89%) had clustered microcalcifications while 7 patients (10.29%) had scattered microcalcifications. Microcalcifications can occur in benign and malignant diseases. While evaluating clustered microcalcifications, few criteria have been established to determine malignant clustered microcalcifications, these include specific and nonspecific …

Patient Expectations Of Full Body Ct Screening, Carole Tanenbaum Kolber

Seton Hall University Dissertations and Theses (ETDs)

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Unenhanced Helical Ct Of Ureterolithiasis: Incidence Of Secondary Urinary Tract Findings, J Yaqoob, M U. Usman, V Bari, K Munir, F Mosharaf

Department of Radiology

Objective: To determine the incidence of secondary signs of obstruction in patients with ureteral stones on unenhanced helical CT scans.MATERIAL AND Methods: Three hundred consecutive patients with suspected renal colic referred by the emergency department for an unenhanced helical CT scan were evaluated. One hundred and thirty two patients with ureteric calculi were viewed prospectively for the secondary signs of obstruction, which include hydronephrosis, hydroureter, perinephric stranding, nephromegaly, periureteral edema and difference in attenuation between acutely obstructed kidney and unobstructed kidney.Results: In the evaluated 132 patients, calculi were present in the proximal, mid and distal ureter in 12, 18 and …

Measured Effects Of Rapid Palatal Expansion On Nasal Cavity Volume Utilizing Cbct, Jon Neal Robinson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to evaluate and predict the expected changes that occur in the nasal cavity volume following rapid palatal expansion. Eighteen subjects (11 female, 7 male), ages 9 to 18, requiring rapid palatal expansion in conjunction with comprehensive orthodontic treatment, were selected for the study. Rapid palatal expansion was accomplished using the standard, banded hyrax appliance. Three-dimensional cone beam computed tomograms using the NewTom 9000™ were acquired before and after expansion. Serial coronal slices of the nasal cavity were made using the QV9000™ software program. The resultant serial images were imported into 3-D Doctor™ for analysis …

Socio-Economic And Diagnostic Aspects Of Tuberculosis In Pakistan, Saba Sohail

Department of Radiology

No abstract provided.

Situs Ambiguous, Saba Sohail, Mukhtiar Ahmed Memon, Allah Rakhiyo

Department of Radiology

The case of a female child is described who presented with recurrent respiratory infections and "recurrent right subphrenic abscess." Detailed radiological work-up identified situs ambiguous abdominis with bronchiectasis, duodenal malrotation, umbilical hernia and spina bifida.

Interpreting Hemoglobin And Water Concentration, Oxygen Saturation, And Scattering Measured In Vivo By Near-Infrared Breast Tomography, Subhadra Srinivasan, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, Christine Kogel, Sandra Soho, Jennifer J. Gibson, Tor D. Tosteson, Steven P. Poplack, Keith D. Paulsen

Dartmouth Scholarship

Near-infrared spectroscopic tomography was used to measure the properties of 24 mammographically normal breasts to quantify whole-breast absorption and scattering spectra and to evaluate which tissue composition characteristics can be determined from these spectra. The absorption spectrum of breast tissue allows quantification of (i) total hemoglobin concentration, (ii) hemoglobin oxygen saturation, and (iii) water concentration, whereas the scattering spectrum provides information about the size and number density of cellular components and structural matrix elements. These property data were tested for correlation to demographic information, including subject age, body mass index, breast size, and radiographic …