Medical Specialties Commons^™

Alcaptonuria And Ochronosis With Diabetes Mellitus And Mycosis Fungoides: A Case Report, Jamshed U. Haq, Roy B. Patton

Henry Ford Hospital Medical Journal

A Negro woman with alcaptonuria, ochronosis, ochronotic arthropathy, diabetes mellitus and mycosis fungoides died of acute renal failure due to diabetic glomerulonephropathy and ochronotic nephrosis. The role of the renal lesions of ochronosis is presented in potentiating the effect of an underlying renal disease producing rapidly progressive kidney failure. The occurrence of ochronosis, diabetes mellitus and mycosis fungoides is apparently coincidental only. Special stains of tissue sections confirm the similarity of melanin and ochronotlc pigment.

Cation Transport I. Metabolic Activity Of The Polyphosphoinositide Complex In Isolated Renal Cortex Tubules, Paul Bartlett, James F. Bossart

Henry Ford Hospital Medical Journal

Although several mechanisms have been proposed to explain the transport of hydrophylilc cations across lipoprotein barriers, the nature and identity of the carrier mechanism have not yet been elucidated. The present communication is concerned with a mechanism postulating that monoesterified phosphate on the inositol moiety of phosphatidyl inositol might provide anionic sites that function as cation carriers via a phosphorylation-dephosphorylation cycle, catalyzed in its simplest sequence by phosphatidyl inositol kinase and diphosphoinositide phosphomonoesterase activities. In this context, one might reasonably expect that turnover of monoesterified phosphate in the polyphosphoinositides of isolated renal cortex tubules would be reduced in tubules in …

The Mechanism Of Formation Of Certain Ventricular Septal Defects: A New Hypothesis, Jami G. Shakibi, Lester Weiss

Henry Ford Hospital Medical Journal

The generally accepted and most common mechanism of the pathogenesis of VSD is the failure of fusion of the conus ridges, atrioventricular cushions and the ventricular muscular septum. Our findings in a study of serial sections of the hearts of newborn gerbils (Meriones unguiculatus) leads us to hypothesize a second, less common, mechanism for the development of VSD, i.e., an exaggeration of the normal process of resorption and atrophy which undermines the septal cusp of the tricuspid valve, thus separating it from the muscular septum. This hypothesis can explain an instance of high membranous VSD in the form of a …

Evaluation Of Cellular-Level Haversian Bone Resorption In Human Hyperparathyroid States: A Preliminary Report, H. M. Frost, A. R. Villanueva, Z. F. Jaworski, P. Meunier, A. G. Shimizu

Henry Ford Hospital Medical Journal

Cellular-level bone resorption was evaluated in 16 patients undergoing renal dialysis and in two with primary hyperparathyroidism, by quantitative histological means using tissue time markers. When averaged over periods greater than two weeks, the individual osteoclasts in these patients resorbed less bone in unit time than normal.

Hfh In The News

Henry Ford Hospital Medical Journal

No abstract provided.

Promethazine-Chlorpromazine Combination In The Treatment Of Unmanageable Psychotic Patients, Armando R. Favazza

Henry Ford Hospital Medical Journal

Administering a combination of promethazine and chlorpromazine to patients with a "galloping psychosis" has an antipsychotic and tranquilizing effect which calms them down to a more manageable and less aggressive state. The drugs are chemically similar; promethazine's actions are strongly potentiated in the combination, so large doses must be given under careful supervision. Case histories demonstrate successful short term management of acutely psychotic, aggressive patients who were a danger to themselves and others.

Pneumatosis Cystoides Intestinalis: The Report Of A Case Associated With Severe Pulmonary Disease And Chronic Lymphocytic Leukemia, Russell J. Crider, Philip Bentlif

Henry Ford Hospital Medical Journal

Pneumatosis cystoides intestinalis is discussed with emphasis on its clinical, radiologic, sigmoidoscopic, surgical and pathological characteristics. The four theories of the etiology of P.Cl. are neoplastic, infectious, nutritional, and mechanical. These theories are discussed, and a case of P.C.I, associated with severe pulmonary disease and chronic lymphocytic leukemia is presented to lend support to the mechanical theory.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Prevalence Rate Of Congenital Heart Disease In Newborn Gerbils (Meriones Unguiculatus): A Preliminary Report, Jami G. Shakibi, Lester Weiss

Henry Ford Hospital Medical Journal

A preliminary report on the prevalence rate of congenital heart disease in newborn gerbils (Meriones unguiculatus) is presented. Serial sections of the entire heart of 100 liveborn gerbils were studied. The prevalence rate of congenital heart disease was 4%. Ventricular septal defect was the most frequent lesion. This is in agreement with previous reports on rats.

Photographic Features Of Benign And Malignant Ulcers, N. V. Carandang, B. M. Schuman, R. J. Priest

Henry Ford Hospital Medical Journal

One hundred and twenty-nine cases of benign gastric ulcer and 17 cases of malignant gastric ulcer studied by intragastric photography are reviewed. The benign ulcer, characterized by symmetrical contour and smooth base, was diagnosed correctly on the initial photographic study in 97.7% of cases. Malignant ulcers were diagnosed correctly in 59% of cases on the first study. The importance of color photography to complement roentgenographic evaluation of gastric ulceration is emphasized.

"Anion-Gap Acidosis" Complicating Diabetic Ketoacidosis: A Commentary On Diagnosis And Management, J. Craig Jurgensen, Fred W. Whitehouse

Henry Ford Hospital Medical Journal

No abstract provided.

Extrasensory Perception In Clinical Medicine, And Other Offenses, Susan Adelman

Henry Ford Hospital Medical Journal

No abstract provided.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Stress Urinary Incontinence In The Human Female: Gravity And Ecomorphologic Influences On Bladder And Urethral Function Of The Human Female, C. Paul Hodgkinson

Henry Ford Hospital Medical Journal

This study was undertaken to determine if the biped stale of the human female constituted a stress force in urethrovesical physiological function. To arrive at realistic conclusions, the ecomorphologic changes incidental to the conquest of gravity by the vertebrates have been reviewed. Accepting the evolutionary precepts as expressed by Hobart Smith that "if all parts of the evolutionary chain were known, it would be impossible to draw a logical distinction between man and nonman, Romer slated "Bone for bone, muscle for muscle, organ for organ, almost every feature of the ape is repeated in the human body. The differences are …

The Application Of "Chemosurgery" In Cancer, George R. Mikhail, Rita E. Blackburn

Henry Ford Hospital Medical Journal

No abstract provided.

Summary Report — Antimicrobial Susceptibility: Tests Results From Henry Ford Hospital Compared With Others Nationally, January-June 1969, Thomas R. Neblett, Jeanne Schotte, John F. Eisses

Henry Ford Hospital Medical Journal

No abstract provided.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Aqueous Microbiology: The Possible Role Of Cell Wall Deficient Bacteria In Uveitis, Philip C. Hessburg, Lioa H. Mattman, Carolyn Barth, Lloyd T. Dutcheshen

Henry Ford Hospital Medical Journal

Samples of aqueous humor were obtained from the anterior chamber of patients with uveitis. Bacterial L-forms, or cell wall deficient forms, were recovered from 11 of 19 eyes with unexplained uveitis. These bacterial variants were cultured on newer, highly specialized media and stained with acridine orange. This stain demonstrates fluorescence of nucleic acids under UV microscopy.

Initial Studies Of Isolated Kidney Perfusion, Stanley G. Dienst, Michael A. Krieg

Henry Ford Hospital Medical Journal

Angiographic and gravametric studies of dog kidneys perfused with electrolyte, Dextran, or albumin solution are presented to demonstrate the possibility of extending organ preservation for transplantation without loss of function. Findings include a reduction in flow and weight gain with the nonprotein solutions and maintenance of flow with albumin solution. Gross changes of the perfused kidneys are also described.

A New Full Orifice Disc Valve For Mitral Replacement, Rodman E. Taber, Yasuharu Imai

Henry Ford Hospital Medical Journal

Because of dissatisfaction with certain features of the currently available ball and disc valve prostheses when implanted in patients with mitral stenosis and a small volume left ventricle, a full orifice discoid valve has been designed which avoids many of these shortcomings. The valve has been tested mechanically in a pulse duplicator and compared lo existing prostheses. High speed cine studies were used to evaluate turbulence. Implantation was carried out in animals. Evaluation by these various methods indicates that the valve is satisfactory for human implantation and may have significant advantages over other artificial valves when used in patients with …

Chronic Acute Hepatitis, Klaus Anselm

Henry Ford Hospital Medical Journal

The current literature concerning chronic acute hepatitis is reviewed. The clinical picture, morphology, laboratory data and etiology are discussed. It is pointed out that much work is still to be done toward fully understanding this disease. A program of treatment is suggested.

Decompressive Laminectomy In The Management Of Spinal Epidural Metastases, J. Speed Rogers, Robert S. Knighton

Henry Ford Hospital Medical Journal

In a series of 60 patients undergoing decompression laminectomy for metastatic malignancy, the median survival was 3.3 months with 11 patients (18%) living for at least one year and ambulating during part of this survival period. Forty-three per cent of the group were able to ambulate for at least some period postoperatively. If a patient could ambulate preoperatively he had a two-thirds chance of ambulating afterwards; conversely, if he could not ambulate preoperatively. he had a two-thirds chance of not ambulating postoperatively. The lymphoma group had the best prognosis. Long lesions and highly vascular tumors fared poorly. Paralysis (as defined …

Eosinophils, Lawrence C. Sweet

Henry Ford Hospital Medical Journal

Despite the fact that the eosinophilic leukocyte has been known as a distinct entity for 123 years and has been the subject of extensive research and numerous scientific papers, its precise function remains an enigma. A diverse array of clinical conditions are known to be associated with eosinophilia but even here the role of this cell in the pathological process remains unknown. Recent experimenlal work suggests that allergens, antigens, antigen-antibody complexes, and components of complement may function as eosinophilotactic stimuli. Eosinophils phagocytize antigen-antibody complexes as well as a variety of particulate substances. Their granules have been identified as lysosomes and …

Scrotal Inflation: A New Cause For Subcutaneous, Mediastinal And Retroperitoneal Emphysema, George Bush, Robert K. Nixon

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Barriers To Attainment Of Health Care In West Central Maine : A Critique By The Poor, Health Facilities Planning Council

Maine Collection

Barriers to Attainment of Health Care in West Central Maine : A Critique by the Poor

"Conducted by the Health Facilities Planning Council, 11 Parkwood Drive, Augusta, Maine under contract to Maine Department of Health and Welfare, June, 1969."

Contents: Foreword / Table of Contents / Introduction / Map / Franklin County / Housing / Dental Rot / Franklin County Memorial Hospital / Family Planning / RN's / State Public Health Nurses / Unmet Health Needs / The Last Outpost / Home Visit in Farmington Falls / Home Visit in Industry / Home Visit in Rangeley Area / Conversations on …

The Clinical Use Of Fluorine18 In Bone Scanning, R. A. Gatesi, A. T. Vulpetti, T. L. Kosnik, W. G. Tucker, R. W. Talley

Henry Ford Hospital Medical Journal

Roentgenograms are frequently inadequate in the detection of early osseous metastases. Isotope bone scan is a more sensitive diagnostic procedure. Reported here are findings on 40 patients with known or suspected osseous involvement using the short-lived radionuclide 18F. Comparison with standard roentgenograms and clinical follow-up demonstrated 11 early detections. 18F was found to be a very suitable agent for isotope bone scanning. Ilustrative cases are presented

Primary Closure And Iliac Osteotomy In The Treatment Of Exstrophy Of The Bladder: A Case Report, Louis Z. Shifrin, Arthur Johnson, Lester Weiss

Henry Ford Hospital Medical Journal

Exstrophy of the bladder is a rare but serious congenital affliction. Untreated, exstrophy is associated with unacceptable morbidity and mortality. A case report is presented in which primary closure of the bladder and bilateral iliac osteotomy was successfully employed to gain anatomic correction of the bladder defect. However, the value of this surgical technique in restoring normal function of the lower urinary tract system is questionable.