Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Specialties (23)
- Diseases (17)
- Chemicals and Drugs (14)
- Life Sciences (9)
- Pharmacy and Pharmaceutical Sciences (8)
-
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (5)
- Cardiology (5)
- Medical Microbiology (5)
- Medical Toxicology (5)
- Public Health (5)
- Biomedical Informatics (4)
- Cardiovascular Diseases (4)
- Chemical Actions and Uses (4)
- Medical Genetics (4)
- Medical Immunology (4)
- Oncology (4)
- Pharmacology, Toxicology and Environmental Health (4)
- Therapeutics (4)
- Amino Acids, Peptides, and Proteins (3)
- Anatomy (3)
- Biochemical Phenomena, Metabolism, and Nutrition (3)
- Chemical and Pharmacologic Phenomena (3)
- Gastroenterology (3)
- Infectious Disease (3)
- Internal Medicine (3)
- Medical Biochemistry (3)
- Medical Education (3)
- Institution
-
- LSU Health New Orleans (13)
- Marshall University (4)
- The Texas Medical Center Library (4)
- Thomas Jefferson University (4)
- University of Kentucky (3)
-
- University of Tennessee Health Science Center (3)
- Bridgeport Hospital (2)
- The British University in Egypt (2)
- United Arab Emirates University (2)
- Virginia Commonwealth University (2)
- Advocate Health - Midwest (1)
- Case Western Reserve University (1)
- Children's Mercy Kansas City (1)
- Eastern Illinois University (1)
- Franklin University (1)
- George Fox University (1)
- HCA Healthcare (1)
- James Madison University (1)
- Kennesaw State University (1)
- Philadelphia College of Osteopathic Medicine (1)
- Rochester Regional Health (1)
- Roseman University of Health Sciences (1)
- University of New Mexico (1)
- University of North Florida (1)
- University of Rhode Island (1)
- University of South Carolina (1)
- University of South Dakota (1)
- University of Texas Rio Grande Valley (1)
- University of Texas at Tyler (1)
- University of the Incarnate Word (1)
- Keyword
-
- Humans (3)
- Hypertension (3)
- Inflammation (3)
- Animals (2)
- Antioxidant (2)
-
- Chemotherapy (2)
- Heart failure (2)
- Invasion (2)
- Metabolism (2)
- Reactive oxygen species (ROS) (2)
- Signal Transduction (2)
- Toxicity (2)
- 12/15-Lipoxygenase (1)
- 17Beta-Estradiol (1)
- <p>Breast – Cancer – Patients.</p> <p>Breast – Cancer – Causes.</p> <p>Obesity – Cancer.</p> (1)
- <p>Disulfiram.</p> <p>Staphylococcus aureus infections.</p> <p>Methicillin resistance.</p> <p>Antibacterial agents.</p> <p>High performance liquid chromatography.</p> <p>Thiamin pyrophosphate.</p> <p>Enzymes.</p> <p>Coenzymes.</p> <p>Biosynthesis.</p> <p>Amino acids -- Metabolism.</p> (1)
- <p>Opioid abuse – Treatment.</p> <p>Pregnant women – Drug use.</p> (1)
- AKT (1)
- ASK1 (1)
- Acute coronary syndrome (1)
- Acute liver injury (1)
- Adrenaline (1)
- Adverse effects (1)
- Agglutination (1)
- Akkermansia muciniphila (1)
- Angiotensin II (1)
- Anti-epileptic (1)
- Anti-inflammatory agent (1)
- Antidepressant (1)
- Antidiabetic (1)
- Publication
-
- School of Medicine Faculty Publications (9)
- Faculty, Staff and Student Publications (4)
- School of Graduate Studies Faculty Publications (4)
- Theses and Dissertations (ETD) (3)
- Theses, Dissertations and Capstones (3)
-
- Pharmacy (2)
- Posters (2)
- Theses and Dissertations (2)
- Advances in Clinical Medical Research and Healthcare Delivery (1)
- Aesculapius Journal (Health Sciences & Medicine) (1)
- All Doctor of Nursing Practice (DNP) Scholarly Projects (1)
- Annual Research Symposium (1)
- Biotechnology Theses (1)
- College of Population Health Faculty Papers (1)
- Computer Science ETDs (1)
- DNP Projects (1)
- Department of Biochemistry and Molecular Biology Faculty Papers (1)
- Department of Pharmacology and Experimental Therapeutics Faculty Papers (1)
- Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers (1)
- Doctor of Medical Science (DMSc) (1)
- Faculty Scholarship (1)
- HCA Healthcare Journal of Medicine (1)
- Journal of Patient-Centered Research and Reviews (1)
- Marshall Journal of Medicine (1)
- Master of Science in Nursing Final Projects (1)
- Masters Theses (1)
- Office of Research Faculty and Staff Publications (1)
- PANDION: The Osprey Journal of Research and Ideas (1)
- Pharmacology and Nutritional Sciences Faculty Publications (1)
- Pharmacology and Toxicology Faculty Publications (1)
- Publication Type
Articles 61 - 61 of 61
Full-Text Articles in Medical Pharmacology
Modulation Of Tlr4/Nf-Κb, Nrf2/Ho-1 And Pi3k/Akt Signaling By Cilostazol Mitigates Lipopolysaccharide-Induced Septic Acute Kidney Injury, Ahmed F. Mohamed Dr., Helmy Said Dr, Hala F. Zaki, Marwa M. Safar Prof. Dr.
Modulation Of Tlr4/Nf-Κb, Nrf2/Ho-1 And Pi3k/Akt Signaling By Cilostazol Mitigates Lipopolysaccharide-Induced Septic Acute Kidney Injury, Ahmed F. Mohamed Dr., Helmy Said Dr, Hala F. Zaki, Marwa M. Safar Prof. Dr.
Pharmacy
Aim: Cilostazol was investigated as a protective agent against lipopolysaccharide (LPS)-associated acute kidney damage in mice. Methods: Cilostazol (50 mg/kg/day; p.o.) administered for 7 consecutive days before a single LPS dose (2 mg/kg; i.p.). Results: Cilostazol hampered serum creatinine, cystatin C, and renal kidney injury molecule-1 and neutrophil gelatinase associated lipocalin; repressed toll-like receptor 4 and MyD88 transcription, as well as nuclear factor-kappa B p65, interleukin-1b, and malondialdehyde content; and boosted Nrf2 mRNA expression, hemeoxygenase-1 activity, and reduced glutathione content. This was synchronous with an upregulation of p-phosphoinositide 3-kinase and p-Akt expressions. Conclusion: Collectively, cilostazol prevented LPS renal injury, which …