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Articles 481 - 481 of 481
Full-Text Articles in Medical Genetics
The Conversion Of Cytidylic Acid To Deoxycytidylic Acid In Rat Kidney, Judith Marie Werderitsch
The Conversion Of Cytidylic Acid To Deoxycytidylic Acid In Rat Kidney, Judith Marie Werderitsch
Master's Essays (1922 - )
Evidence was presented in 1949 by Bendich, Getler, and Brown (2), that the free pyrimidine base, cytosine, was not incorporated into the nucleotides of deoxyribonucleic acid (DNA). Further studies by Hammarsten, Reichard, and Saluste (9) with cytidine and those by Roll, Weinfeld, and Carroll (26) with cytidylic acid, showed that the nucleoside and nucleotide derivatives were well incorporated into DNA. These experiments indicated that the conversion of the riboside (or ribotide) to the deoxyribose form had occurred with the nucleosidic linkage intact. This theory was further substantiated by Rose and Schweigert (29) using cytidylic acid incorporation into the total viscera …