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Articles 31 - 35 of 35

Full-Text Articles in Medical Anatomy

The Reliability Of The Navicular Drop Test And Its Transferability To Dynamic Movement, Joshua Krispin Jan 2017

The Reliability Of The Navicular Drop Test And Its Transferability To Dynamic Movement, Joshua Krispin

College of Graduate Studies: Theses & Dissertations

Background: Navicular drop can be defined as the distance the navicular tuberosity moves from a standing weight bearing to a standing neutral position, as the subtalar joint moves from a relaxed position to a neutral position. Navicular drop is an important measurement for clinicians used to describe foot function, pronation, and excessive movement seen in several pathologies. Objective: The purpose of this study is to see if navicular drop is influenced by mode or speed of locomotion, if it is will there be other influences such as the forefoot and heel soft tissue, and will those factors influence those measures. …


Oligodendrocyte Ablation As A Tool To Study Demyelinating Diseases, Ahdeah Pajoohesh-Ganji, Robert H. Miller Jun 2016

Oligodendrocyte Ablation As A Tool To Study Demyelinating Diseases, Ahdeah Pajoohesh-Ganji, Robert H. Miller

Anatomy and Regenerative Biology Faculty Publications

Multiple sclerosis (MS) is an autoimmune mediated neurodegenerative disease characterized by demyelination and oligodendrocyte (OL) loss in the central nervous system and accompanied by local inflammation and infiltration of peripheral immune cells. Although many risk factors and symptoms have been identified in MS, the pathology is complicated and the cause remains unknown. It is also unclear whether OL apoptosis precedes the inflammation or whether the local inflammation is the cause of OL death and demyelination. This review briefly discusses several models that have been developed to specifically ablate oligodendrocytes in an effort to separate the effects of demyelination from inflammation.


Il-15 Mediates Mitochondrial Activity Through A Ppar𝛿-Dependent-Ppar𝛼-Independent Mechanism In Skeletal Muscle Cells, Shantaé M. Thornton, James E. Krolopp, Marcia J. Abbott Jan 2016

Il-15 Mediates Mitochondrial Activity Through A Ppar𝛿-Dependent-Ppar𝛼-Independent Mechanism In Skeletal Muscle Cells, Shantaé M. Thornton, James E. Krolopp, Marcia J. Abbott

Health Sciences and Kinesiology Faculty Articles

Molecular mediators of metabolic processes, to increase energy expenditure, have become a focus for therapies of obesity. The discovery of cytokines secreted from the skeletal muscle (SKM), termed “myokines,” has garnered attention due to their positive effects on metabolic processes. Interleukin-15 (IL-15) is a myokine that has numerous positive metabolic effects and is linked to the PPAR family of mitochondrial regulators. Here, we aimed to determine the importance of PPAR𝛼 and/or PPAR𝛿 as targets of IL-15 signaling. C2C12 SKM cells were differentiated for 6 days and treated every other day with IL-15 (100 ng/mL), a PPAR𝛼 inhibitor (GW-6471), a PPAR𝛿 …


Gender Differences In Frontal Plane Lower Extremity Kinetic Variability During Landing, Andrew Nordin Apr 2013

Gender Differences In Frontal Plane Lower Extremity Kinetic Variability During Landing, Andrew Nordin

Interdisciplinary Research Scholarship Day

Investigations of human movement variability have been used as a
means of exploring neuromotor functioning, where performance variability is
thought to provide the system with flexibility and a mechanism for adaptation to
movement repetition [1,2,4,6]. Operationally, variability has been considered to
fall within optimal limits (Figure 1), while excessively high or low variability has
been implicated in injury susceptibility [1,2,4,6]. Landing has been explored
due to a high incidence of injury in athletic performance, as well as the ability
to easily control task demands through increases in landing height [3,4].
The purpose of this investigation was to evaluate changes in …


Intracranial Surgery, William T. Grant Apr 1947

Intracranial Surgery, William T. Grant

Medical Arts and Sciences: A Scientific Journal of the College of Medical Evangelists

No abstract provided.