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2020

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Articles 1231 - 1260 of 1778

Full-Text Articles in Medical Sciences

Role Of Chondrocyte Antigen Presentation In Osteoarthritis, Panjana Sengprasert Jan 2020

Role Of Chondrocyte Antigen Presentation In Osteoarthritis, Panjana Sengprasert

Chulalongkorn University Theses and Dissertations (Chula ETD)

Osteoarthritis (OA) is an inflammatory disorder characterized by degeneration of joint components, especially the cartilage. Chondrocytes are found in articular cartilage and play a role in cartilage production and degradation. Several studies found that chondrocytes not only control the cartilage metabolism, but also play a role in immune responses. However, the role of chondrocytes in the pathogenesis of OA is still unclear. In this study, we investigated the responses of OA chondrocytes after stimulating with IFN-γ and proteoglycan aggrecan and also determined antigen presentation function of chondrocytes to present proteoglycan aggrecan peptide to T cells. We found that OA chondrocyte …

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An Incidental Finding Of Gastric Mucosa-Associated Lymphoma (Maltoma) In A Sleeve Gastrectomy With Literature Review, Brenda Mai, Michaelangelo Friscia, Pamela Younes, Jaiyeola Thomas-Ogunniyi, Lei Chen Jan 2020

An Incidental Finding Of Gastric Mucosa-Associated Lymphoma (Maltoma) In A Sleeve Gastrectomy With Literature Review, Brenda Mai, Michaelangelo Friscia, Pamela Younes, Jaiyeola Thomas-Ogunniyi, Lei Chen

Faculty, Staff and Student Publications

Mucosal-associated lymphoid tissue (MALT) lymphoma can typically be identified as a mass lesion or nodularity endoscopically and macroscopically. We report an incidental finding of a Helicobacter pylori gastric mucosal-associated lymphoid tissue (MALT) lymphoma in a sleeve gastrectomy specimen with no gross examination findings.

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Anterior Cruciate Ligament Injury-Induced Alterations In Inflammation And Muscle Physiology, Emily R. Hunt Jan 2020

Anterior Cruciate Ligament Injury-Induced Alterations In Inflammation And Muscle Physiology, Emily R. Hunt

Theses and Dissertations--Rehabilitation Sciences

Long term weakness and atrophy of the quadriceps muscle are a direct result of anterior cruciate ligament (ACL) injuries and persist for up to 10 years post injury. Muscle atrophy ensues regardless of ligamentous reconstruction surgery, indicating that muscle atrophy following injury is a function of the ligament rupture and not reconstruction surgery. Elucidating the mechanisms underlying quadriceps atrophy following ACL rupture is crucial for developing interventions to restore proper quadriceps size and mitigate weakness thereby allowing for improved patient function. In addition to understanding the specific mechanisms that contribute to quadriceps atrophy following ACL rupture, the timing of atrophic …

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Determining The Role Of Satellite Cells During Skeletal Muscle Adaptation, Davis A. Englund Jan 2020

Determining The Role Of Satellite Cells During Skeletal Muscle Adaptation, Davis A. Englund

Theses and Dissertations--Rehabilitation Sciences

Physical inactivity, advancing age, limb immobilization, degenerative diseases and various systemic diseases (many cancers, sepsis, HIV, COPD, kidney disease) all lead to skeletal muscle wasting. The loss of muscle mass is of major clinical importance because it leads to an increased risk for morbidity, disability, and the loss of independence; collectively contributing to a substantive increase in healthcare utilization and cost. The prevalence of cachexia (disease-induced muscle wasting) can reach as high as 80% in certain patient populations and the average cost per hospital stay is $4,641 more than in non-cachectic patients. Direct healthcare costs attributable to sarcopenia were estimated …

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Lobectomy May Not Be Suitable For Patients With Follicular Neoplasm Cytology, Beki̇r Uçan, Mustafa Şahi̇n, Mustafa Özbek, Muhammed Kizilgül, Müyesser Sayki Arslan, Mustafa Çalişkan, Güleser Saylam, Erman Çakal Jan 2020

Lobectomy May Not Be Suitable For Patients With Follicular Neoplasm Cytology, Beki̇r Uçan, Mustafa Şahi̇n, Mustafa Özbek, Muhammed Kizilgül, Müyesser Sayki Arslan, Mustafa Çalişkan, Güleser Saylam, Erman Çakal

Turkish Journal of Medical Sciences

Background/aim: The most appropriate surgical management of follicular neoplasm/suspicious for follicular neoplasm (FN) lesions is still contradictory. We aimed to evaluate the data of our patients with follicular neoplasm treated with thyroidectomy. Materials and methods: We retrospectively analyzed the data of 74 patients who were diagnosed with follicular neoplasm cytology (FN cytology) by fine needle aspiration biopsy (FNAB) and had undergone total thyroidectomy or lobectomy with isthmectomy (LwI). Results: We examineda total of 74 patients, of which 64 (83.7%) were female and 10 (16.3%) were male. The malignancy rate in the pathological examinations of these patients was 31/74 (41.9%). The …

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Total Oxidant And Antioxidant Status And Paraoxonase 1 Levels Ofchildren With Noncystic Fibrosis Bronchiectasis, Ahmet Hakan Gedi̇k, Erkan Çakir, Aysel Vehapoğlu Türkmen, Ömer Faruk Özer, Sare Betül Kaygusuz Jan 2020

Total Oxidant And Antioxidant Status And Paraoxonase 1 Levels Ofchildren With Noncystic Fibrosis Bronchiectasis, Ahmet Hakan Gedi̇k, Erkan Çakir, Aysel Vehapoğlu Türkmen, Ömer Faruk Özer, Sare Betül Kaygusuz

Turkish Journal of Medical Sciences

Background/aim: To evaluate total oxidant status (TOS), total antioxidant capacity (TAC), and paraoxonase 1 (PON1) levels in children with noncystic fibrosis (CF) bronchiectasis (BE), and to compare these levels with those of healthy controls. The study parameters were also evaluated according to some demographic, anthropometric, and clinical characteristics, as well as lung functions. Materials and methods: Enrolled in the study were 118 children with non-CF BE and 68 healthy controls. Serum TOS, TAC, and PON1 levels were determined. Lung function tests were performed by spirometry. Results: Serum TOS was higher in the patients [median 9.54 (IQR 25-75 = 7.05-13.30) µmol …

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Continuous Venovenous Hemodiafiltration In The Treatment Of Newborns With An Inborn Metabolic Disease: A Single Center Experience, Hasan Akduman, Emel Okulu, Fatma Tuba Emi̇noğlu, Tanil Kendi̇rli̇, Gaffari̇ Tunç, Ebru Azapağasi, Oktay Perk, Ömer Erdeve, Begum Atasay, Saadet Arsan Jan 2020

Continuous Venovenous Hemodiafiltration In The Treatment Of Newborns With An Inborn Metabolic Disease: A Single Center Experience, Hasan Akduman, Emel Okulu, Fatma Tuba Emi̇noğlu, Tanil Kendi̇rli̇, Gaffari̇ Tunç, Ebru Azapağasi, Oktay Perk, Ömer Erdeve, Begum Atasay, Saadet Arsan

Turkish Journal of Medical Sciences

Background/aim: Most inborn metabolic diseases are diagnosed during the neonatal period. The accumulation of toxic metabolites may cause acute metabolic crisis with long-term neurological dysfunction and death. Renal replacement therapy (RRT) modalities allow the efficient removal of toxic metabolites. In this study, we reviewed our experience with continuous venovenous hemodiafiltration (CVVHDF) as RRT for newborns with an inborn metabolic disease.Materials and methods: Patients diagnosed with an inborn metabolic disease and who received CVVHDF treatment at our neonatal intensive care unit between January 2014 and December 2017 were included in this study. Their demographic and clinical data were collected, and the …

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Twenty Children With Non-Wilms Renal Tumors From A Reference Center In Central Anatolia, Turkey, Ekrem Ünal, Ebru Yilmaz, Alper Özcan, Bi̇lgen Işik, Musa Karakükcü, Cüneyt Turan, Hülya Akgün, Fi̇gen Öztürk, Abdulhaki̇m Coşkun, Mehmet Aki̇f Özdemi̇r, Türkan Patiroğlu Jan 2020

Twenty Children With Non-Wilms Renal Tumors From A Reference Center In Central Anatolia, Turkey, Ekrem Ünal, Ebru Yilmaz, Alper Özcan, Bi̇lgen Işik, Musa Karakükcü, Cüneyt Turan, Hülya Akgün, Fi̇gen Öztürk, Abdulhaki̇m Coşkun, Mehmet Aki̇f Özdemi̇r, Türkan Patiroğlu

Turkish Journal of Medical Sciences

Background/aim: Non-Wilms renal tumors (NWRTs) are rarely encountered in children. The aim of this study is to determine the treatment strategies, prognosis, outcomes, and survival of children with NWRTs at Erciyes University in Kayseri, Turkey.Materials and methods: Medical records of all patients (n = 20) treated for NWRTs over a 23-year period (1995-2018) were reviewed retrospectively.Results: There was male predominance (female/male: 7/13); the median age at diagnosis was 3.2 years old (0.1-13.5 years old). The major histological groups included mesoblastic nephroma (MBN), (n: 5, 25%), malignant rhabdoid tumor (MRT), (n: 5, 25%), renal cell carcinoma, (n: 3, 15%), inflammatory myofibroblastic …

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The Surgical Outcomes Of Trans-Scaphoid Perilunate Fracture-Dislocations, Cemal Kural, Bülent Tanriverdi̇, Ersi̇n Erçi̇n, Emre Baca, Murat Yilmaz Jan 2020

The Surgical Outcomes Of Trans-Scaphoid Perilunate Fracture-Dislocations, Cemal Kural, Bülent Tanriverdi̇, Ersi̇n Erçi̇n, Emre Baca, Murat Yilmaz

Turkish Journal of Medical Sciences

Background/aim: Trans-scaphoid perilunate fracture-dislocation (TSPFD) is a rare injury. TSPFD is a fracture-dislocation that severely disrupts the anatomical structure of the carpal bones and may occur as a result of a high energy trauma of the wrist or a fall on an open hand. In this study, the aim is to provide midterm clinical and radiological evaluations of cases diagnosed and treated as TSPFD.Materials and methods: Eleven patients diagnosed with TSPFD as a result of wrist trauma were treated surgically and were analysed retrospectively. Clinical and radiological follow-up of the cases was evaluated. The mean age of the patients was …

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Anti-Interleukin-6 (Tocilizumab) Therapy In Takayasu's Arteritis: A Real Life Experience, Levent Kiliç, Ömer Karadağ, Abdulsamet Erden, Alper Sari, Berkan Armağan, Gözde Kübra Yardimci, Esra Firat Şentürk, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Ali̇ Akdoğan Jan 2020

Anti-Interleukin-6 (Tocilizumab) Therapy In Takayasu's Arteritis: A Real Life Experience, Levent Kiliç, Ömer Karadağ, Abdulsamet Erden, Alper Sari, Berkan Armağan, Gözde Kübra Yardimci, Esra Firat Şentürk, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Ali̇ Akdoğan

Turkish Journal of Medical Sciences

Background/aim: Tumour necrosis factor inhibitors and anti-interleukin-6 (anti-IL-6) therapies are increasingly being used in Takayasu's arteritis (TA) patients who are unresponsive to corticosteroids ± conventional immunosuppressive agents.The aim of this study is to assess the efficacy and safety of anti-IL-6 (tocilizumab) therapy in refractory TA patients in real life.Materials and methods: Fifteen TA patients (86.7% were female) who received at least 3 cycles of tocilizumab therapy were retrospectively assessed by clinical, laboratory, and radiological evaluations before and after tocilizumab therapy. Results: The median (min-max) age of the patients at evaluation was 35 (20-58) years and the median disease duration from …

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Effects Of Stage I Hypertension On The Recovery Of Early Postoperative Attention Network Function In Elderly Patients Undergoing Elective Hip Or Knee Arthroplasty Surgery, Dan Zhao, Jun Li, Rui Yang, Guanghong Xu Jan 2020

Effects Of Stage I Hypertension On The Recovery Of Early Postoperative Attention Network Function In Elderly Patients Undergoing Elective Hip Or Knee Arthroplasty Surgery, Dan Zhao, Jun Li, Rui Yang, Guanghong Xu

Turkish Journal of Medical Sciences

Background/aim: Hypertension is an important risk factor for cognitive impairment. This study explored whether elderly patients with stage I hypertension (HPs) and normotensive patients (NPs) showed differences in the recovery of postoperative attention network function according to the attentional network test (ANT) performance.Materials and methods: Of 110 patients screened, 25 HPs and 25 NPs completed this study. The Mini-Mental State Examination (MMSE) was applied to all participants before the operation and the ANT (on days 2 and 7) after the operation. All participants completed 1 day preoperatively and the ANT on postoperative days (PODs) 2 and 7.Results: Compared with NPs, …

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Relationship Of Mesenteric Panniculitis With Visceral And Subcutaneous Adipose Tissue, Çi̇ğdem Özer Gökaslan, Eranil Aslan, Emi̇n Demi̇rel, Ayli̇n Yücel Jan 2020

Relationship Of Mesenteric Panniculitis With Visceral And Subcutaneous Adipose Tissue, Çi̇ğdem Özer Gökaslan, Eranil Aslan, Emi̇n Demi̇rel, Ayli̇n Yücel

Turkish Journal of Medical Sciences

Background/aim: Mesenteric panniculitis (MP) is an idiopathic benign disease characterized by fat necrosis, chronic inflammation, and fibrosis. The relationship between obesity and chronic low-grade inflammation has been reported. This study investigated the relationship of MP diagnosed using multidetector computed tomography (MDCT) with visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) areas.Materials and methods: We retrospectively enrolled 104 patients with no radiological findings other than MP. Additionally, 76 individuals without any indicative radiological findings were included as controls. VAT and SAT were separately calculated (cm2) using a 3-dimensional workstation. The abdominal circumference was measured (cm). Results: The mean abdominal circumference …

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Multicenter Study Of Levodopa Carbidopa Intestinal Gel In Parkinson's Disease: The Turkish Experience, Murat Gülteki̇n, Çağri Ulukan, Sabi̇ha Tezcan Aydemi̇r, Okan Doğu, Haşmet Ayhan Hanağasi, Başar Bi̇lgi̇ç, Ayşe Bora Tokçaer, Rai̇f Çakmur, Bülent Eli̇bol, Meral Mi̇rza, Di̇lek Günal, Çi̇ğdem Sevda Erer Özbek, Gülay Kenangi̇l, Özge Yilmaz Küsbeci̇, Muhi̇tti̇n Cenk Akbostanci Jan 2020

Multicenter Study Of Levodopa Carbidopa Intestinal Gel In Parkinson's Disease: The Turkish Experience, Murat Gülteki̇n, Çağri Ulukan, Sabi̇ha Tezcan Aydemi̇r, Okan Doğu, Haşmet Ayhan Hanağasi, Başar Bi̇lgi̇ç, Ayşe Bora Tokçaer, Rai̇f Çakmur, Bülent Eli̇bol, Meral Mi̇rza, Di̇lek Günal, Çi̇ğdem Sevda Erer Özbek, Gülay Kenangi̇l, Özge Yilmaz Küsbeci̇, Muhi̇tti̇n Cenk Akbostanci

Turkish Journal of Medical Sciences

Background/aim: Our purpose was to determine the efficacy of levodopa carbidopa intestinal gel (LCIG) in a series of Turkish patients with Parkinson's disease (PD). Materials and methods: We had telephone calls with 54 patients from 11 neurology centers who were on LCIG treatment, and 44 patients or their caregivers were included in an eight-item survey between September 2015 and June 2016. The reliability and validity of the survey were evaluated with intraclass correlation coefficients for every question separately.Results: Average age of the patients were 63.48 and the duration of PD was 12.79 years. Average LCIG treatment period was 15.63 months. …

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Results Of Genicular Nerve Ablation By Radiofrequency In Osteoarthritis-Related Chronic Refractory Knee Pain, Zafer Yasi̇n Konya, Suna Akin Takmaz, Hülya Başar, Bülent Baltaci, Gülçi̇n Babaoğlu Jan 2020

Results Of Genicular Nerve Ablation By Radiofrequency In Osteoarthritis-Related Chronic Refractory Knee Pain, Zafer Yasi̇n Konya, Suna Akin Takmaz, Hülya Başar, Bülent Baltaci, Gülçi̇n Babaoğlu

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate the medium- to long-term effects of radiofrequency (RF) ablation of genicular nerves for chronic refractory knee pain due to osteoarthritis (OA).Materials and methods: Forty-eight patients who underwent RF ablation of the genicular nerves were evaluated retrospectively. The visual analogue scale (VAS) score, Western Ontario and McMaster universities osteoarthritis index (WOMAC index), opioid and nonsteroidal antiinflammatory drug (NSAID) use score, quality of life score, and treatment satisfaction score were examined at 1, 3, and 6 months after the procedure.Results: The mean VAS scores were significantly lower at the 1-, 3-, and 6-month …

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Dermoscopy Of Oral Mucocele: Three Types Of Extravasation Mucoceles, Erhan Ayhan, Serdar Feri̇t Toprak, Şeyhmus Kaya, Şeri̇ke Akkaynak Jan 2020

Dermoscopy Of Oral Mucocele: Three Types Of Extravasation Mucoceles, Erhan Ayhan, Serdar Feri̇t Toprak, Şeyhmus Kaya, Şeri̇ke Akkaynak

Turkish Journal of Medical Sciences

Background/aim: Dermoscopy is a diagnostic tool that assists in imaging the epidermis and dermis. Although it has also started to be used to diagnose nonmelanocytic lesions recently, it has not been tested much on oral mucosal masses, such as oral mucoceles. This study aimed to investigate whether dermoscopy is a valuable tool in diagnosing oral mucoceles.Materials and methods: In this study, the clinical and dermoscopic features of 21 oral mucocele lesions of 21 patients (11 females, 10 males) aged between 6 and 38 years who were confirmed histopathologically were evaluated.Results: Of the lesions studied, 95.2% (20) were extravasation and 4.8% …

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Severe Neonatal Hyperbilirubinemia In The Southeast Region Of Turkey, Özlem Bozkurt, Ebru Yücesoy, Baran Oğuz, Ömür Akinel, Mehmet Fati̇h Palali, Nurgül Ataş Jan 2020

Severe Neonatal Hyperbilirubinemia In The Southeast Region Of Turkey, Özlem Bozkurt, Ebru Yücesoy, Baran Oğuz, Ömür Akinel, Mehmet Fati̇h Palali, Nurgül Ataş

Turkish Journal of Medical Sciences

Background/aim: Severe neonatal hyperbilirubinemia is an important cause of morbidity and mortality in developing countries. The aim was to assess etiologic reasons for development of severe hyperbilirubinemia and define risk factors for exchange transfusion and acute bilirubin encephalopathy (ABE) in Şanlıurfa located in the southeast region of Turkey.Materials and methods: An observational cohort study included 115 infants with ≥35 weeks of gestation admitted with diagnosis of severe hyperbilirubinemia in a period of 18 months. Potential risk factors associated with exchange transfusion and development of ABE were analyzed.Results: Among 115 infants, 67 (58.3%) received exchange transfusion and 45 (39.1%) developed ABE. …

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Effects Of Early Mobilization And Weight Bearing On Postoperative Walking Ability And Pain In Geriatric Patients Operated Due To Hip Fracture: A Retrospective Analysis, Tolgahan Kuru, Haci Ali̇ Olçar Jan 2020

Effects Of Early Mobilization And Weight Bearing On Postoperative Walking Ability And Pain In Geriatric Patients Operated Due To Hip Fracture: A Retrospective Analysis, Tolgahan Kuru, Haci Ali̇ Olçar

Turkish Journal of Medical Sciences

Background/aim: Hip fractures in older adults are associated with high morbidity, mortality, and subsequent hospital costs and decreased quality of life. The objective of this study was to evaluate geriatric patients who underwent partial prosthesis surgery following hip fracture and effects of early mobilization and weight bearing on postoperative walking ability and pain. Materials and methods: A total of 52 geriatric patients with intertrochanteric and femoral neck fractures were included in the study. Patients' service files, system records, pre- and postoperative X-rays were retrospectively reviewed.Results: There were 52 patients in the study group with 36 (69.2%) being female. The mean …

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Predictive Factors For Treatment Success Of Transforaminal Epidural Steroid Injection In Lumbar Disc Herniation-Induced Sciatica, Savaş Şencan, Alp Eren Çelenli̇oğlu, Ruslan Asadov, Osman Hakan Gündüz Jan 2020

Predictive Factors For Treatment Success Of Transforaminal Epidural Steroid Injection In Lumbar Disc Herniation-Induced Sciatica, Savaş Şencan, Alp Eren Çelenli̇oğlu, Ruslan Asadov, Osman Hakan Gündüz

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to identify predictive factors for treatment success in transforaminal epidural steroid injection in patients with lumbar disc herniation-induced sciatica. Materials and methods: A total of 219 patients who were diagnosed with unilateral sciatica and underwent transforaminal epidural steroid injections at the level of L4-5, L5-S1, or S1 neural foramina between March 2016 and May 2018 were retrospectively analyzed. The presence of transitional vertebrae and the grade of nerve root compression were evaluated by a radiologist. Data including age, sex, body mass index, duration of symptoms, injection levels, and pain scores were recorded. Pain …

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An Epidemiologic Study Of Physician-Diagnosed Chronic Obstructive Pulmonary Disease In The Turkish Population: Copdturkey-1, Tarkan Özdemi̇r, Ni̇lgün Yilmaz Demi̇rci̇, Hati̇ce Kiliç, Orhan Koç, Akin Kaya, Can Öztürk Jan 2020

An Epidemiologic Study Of Physician-Diagnosed Chronic Obstructive Pulmonary Disease In The Turkish Population: Copdturkey-1, Tarkan Özdemi̇r, Ni̇lgün Yilmaz Demi̇rci̇, Hati̇ce Kiliç, Orhan Koç, Akin Kaya, Can Öztürk

Turkish Journal of Medical Sciences

Background/aim: Chronic obstructive pulmonary disease (COPD) is a common disease characterized by persistent airflow limitation and respiratory symptoms. It is a leading cause of morbidity and mortality all over the world. Our data on COPD in Turkey are limited. This study was intended to examine the epidemiologic characteristics of COPD in the Turkish population, between 2012 and 2016. Materials and methods: This population-based, descriptive, surveillance study examined physician-diagnosed COPD prevalence, incidence, and mortality in Turkey.The database of the Social Security System of Turkey was scanned and ICD-10 J44.0-J44.9 codes for diagnostic and/or therapeutic purposes were evaluated retrospectively. Results: In 2016, …

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Patients With Copd Who Underwent Pulmonary Rehabilitation In Turkey: Prevalence, Distribution, And Mortality, Tarkan Özdemi̇r, İpek Candemi̇r, Pinar Ergün, Mustafa Hami̇dullah Türkkani, Orhan Koç Jan 2020

Patients With Copd Who Underwent Pulmonary Rehabilitation In Turkey: Prevalence, Distribution, And Mortality, Tarkan Özdemi̇r, İpek Candemi̇r, Pinar Ergün, Mustafa Hami̇dullah Türkkani, Orhan Koç

Turkish Journal of Medical Sciences

Background: Pulmonary rehabilitation (PR) is an effective, evidenced-based treatment. Despite its proven effect, it is still underused. The aim of this study was to present the number of patients with chronic obstructive pulmonary disease (COPD) who underwent PR, general mortality percentages, the rate of patients prescribed PR by pulmonologists, and the distribution of institutions where PR was performed between 2008 and 2016 in Turkey. Materials and methods: The documents were obtained from Turkish Institution of Social Insurance. Ages, sexes, and numbers of patients with COPD who underwent PR between 2008 and 2016 were recorded. The number of patients with COPD …

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Cytomorphological Findings In Diagnosis Of Warthin Tumor, Fatma Fulya Köybaşioğlu, Bi̇nnur Önal, Ünsal Han, Ayşegül Adabağ, Ahmet Şahpaz Jan 2020

Cytomorphological Findings In Diagnosis Of Warthin Tumor, Fatma Fulya Köybaşioğlu, Bi̇nnur Önal, Ünsal Han, Ayşegül Adabağ, Ahmet Şahpaz

Turkish Journal of Medical Sciences

Background/aim: To define the cytomorphologic findings leading to difficulties in diagnosis of Warthin tumors (WTs).Materials and methods: Forty-eight histopathologically diagnosed WT patients who had fine needle aspiration cytology preoperatively were reevaluated for defining the presence or absence of lymphocytes, oncocytic cell layer, oncocytic cell papillae, granular debris background, mucoid background, macrophages, polymorphonuclear cells, mast cells, squamous-like cells, atypical vacuolated cytoplasmic cells, and giant cells.Results: Forty-seven tumors were in the parotid gland and one in the submandibular gland. There were 37 (77%) male and 11 (23%) female patients. Cytopathologically in 36 patients the diagnosis was benign neoplasm (WT); in 6, other …

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Impact Of The Demographic And Aetiological Factors And Intraoperative Findings On Postoperative Outcomes In Chronic Otitis Media Surgery, Süleyman Cebeci̇, Mehmet Suat Özbi̇len, İsmet Bayramoğlu, Yusuf Kemal Kemaloğlu, Kadi̇r Kemal Uygur, Yildirim Ahmet Bayazit, Recep Karamert Jan 2020

Impact Of The Demographic And Aetiological Factors And Intraoperative Findings On Postoperative Outcomes In Chronic Otitis Media Surgery, Süleyman Cebeci̇, Mehmet Suat Özbi̇len, İsmet Bayramoğlu, Yusuf Kemal Kemaloğlu, Kadi̇r Kemal Uygur, Yildirim Ahmet Bayazit, Recep Karamert

Turkish Journal of Medical Sciences

Background/aim: Surgical success is related with many factors belonging to both the patient and the disease. This study aims to analyse the preoperative and intraoperative characteristics, the postoperative results, and the factors affecting the surgical success in different types of chronic otitis media (COM).Materials and methods: A total of 1510 ears of 1398 patients who underwent COM surgery were included in the study. Postoperative results were obtained from 376 ears of 356 patients who had been followed after surgery. The demographic characteristics of the patients, such as age and sex, operative findings, preoperative audiological examination results, and final audiometric and …

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Thiol/Disulfide Homeostasis And Ischemia Modified Albumin Levels In Autoimmune Gastritis And Their Relations With Gastric Emptying, Emra Asfuroğlu Kalkan, Serap Boz, Özcan Erel, Sali̇m Neşeli̇oğlu, Çağdaş Kalkan, Ari̇f İrfan Soykan Jan 2020

Thiol/Disulfide Homeostasis And Ischemia Modified Albumin Levels In Autoimmune Gastritis And Their Relations With Gastric Emptying, Emra Asfuroğlu Kalkan, Serap Boz, Özcan Erel, Sali̇m Neşeli̇oğlu, Çağdaş Kalkan, Ari̇f İrfan Soykan

Turkish Journal of Medical Sciences

Background/aim: Autoimmune gastritis is an autoimmune and inflammatory disorder. The aim of this study is to examine dynamic thiol/disulfide homeostasis and ischemia modified albumin levels, and to analyze the association between thiol/disulfide homeostasis and gastric emptying time in autoimmune gastritis. Materials and methods: Thiol/disulfide homeostasis tests and ischemia modified albumin levels were determined in 50 autoimmune gastritis patients and 53 healthy subjects. Patients with delayed and normal gastric emptying were compared by thiol/disulfide homeostasis tests. Results: The results showed that native thiol (μmol/L), total thiol (μmol/L), and native thiol/total thiol ratio (%) of the patients with autoimmune gastritis decreased compared …

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Early Pregnancy After Bariatric Surgery: A Single-Institute Preliminary Experience, Emre Günakan, Hakan Buluş, Yusuf Aytaç Tohma Jan 2020

Early Pregnancy After Bariatric Surgery: A Single-Institute Preliminary Experience, Emre Günakan, Hakan Buluş, Yusuf Aytaç Tohma

Turkish Journal of Medical Sciences

Background/aim: Pregnancy after bariatric surgery is an issue of growing importance with increasing number of women undergoing bariatric surgery. Therefore, in this study we present patients who conceived after sleeve gastrectomy and evaluate the obstetric outcomes. Materials and methods: This retrospective case-control study includes 23 women who conceived after laparoscopic sleeve gastrectomy. Patients were evaluated in two groups according to the number of months between surgery and conception (group 1: ≤12 months; group 2: >12 months). Results: The mean body mass index of patients before surgery and at the time of conception was 46.6 kg/m2 and 29.7 kg/m2, respectively. Nine …

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The Efficacy Of The 3-Dimensional Vibe-Caipirinha-Dixon Technique In The Evaluation Of Pancreatic Steatosis, Ural Koç, Gökhan Ocakoğlu, Oktay Algin Jan 2020

The Efficacy Of The 3-Dimensional Vibe-Caipirinha-Dixon Technique In The Evaluation Of Pancreatic Steatosis, Ural Koç, Gökhan Ocakoğlu, Oktay Algin

Turkish Journal of Medical Sciences

Background/aim: CAIPIRINHA is a new technique in abdominal imaging. Pancreatic steatosis (PS) is a subject of increasing scientific interest. The aim of this study was to investigate the efficacy of the isotropic 3D-VIBE- CAIPIRINHA -DIXON technique on a new generation 3-tesla MR unit in the evaluation of PS.Materials and methods: In this retrospective study, the imaging findings of 49 patients with PS and 41 control subjects were examined. The pancreas-to-spleen ratio (PSR), pancreas-to-muscle ratio (PMR), and pancreatic signal intensity index (PSII) were defined as 3 new parameters and these indexes were calculated from the in-phase/out of phase 3D-VIBE- CAIPIRINHA-DIXON images. …

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Can The Efficacy Of Subacromial Corticosteroid Injection Be Improved Using A Single-Session Mobilization Treatment In Subacromial Impingement Syndrome? A Randomized Single-Blind Controlled Trial, Fazil Kulakli, İlker İlhanli, İlker Fati̇h Sari, Adem Türköz, Canan Çeli̇k Jan 2020

Can The Efficacy Of Subacromial Corticosteroid Injection Be Improved Using A Single-Session Mobilization Treatment In Subacromial Impingement Syndrome? A Randomized Single-Blind Controlled Trial, Fazil Kulakli, İlker İlhanli, İlker Fati̇h Sari, Adem Türköz, Canan Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: The objective in this study is to assess the short-term effects of a single-session mobilization in addition to subacromial corticosteroid (SACS) injection in impingement syndrome.Materials and methods: The study was designed as a prospective randomized controlled single-blind, parallel group clinical trial. Patients (totally 84) were divided randomly into two groups equally. Forty-two patients in Group 1 received mobilization and SACS injection, whereas 42 patients in Group 2 only received SACS injections. A single SACS injection was applied in all patients. Mobilization was administered as a single session right after SACS injection. Patient' evaluations were performed measuring active range of …

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Comparison Of Direct Laryngoscope And Mcgrath Videolaryngoscope In Terms Of Glottic View And Hemodynamics In Bariatric Surgery, Mehmet Çakir, Erhan Özyurt Jan 2020

Comparison Of Direct Laryngoscope And Mcgrath Videolaryngoscope In Terms Of Glottic View And Hemodynamics In Bariatric Surgery, Mehmet Çakir, Erhan Özyurt

Turkish Journal of Medical Sciences

Background/aim: In the recent years, videolaryngoscopes (VL) have emerged as alternative devices to direct laryngoscopes (DL) in difficult intubation situations. Therefore, we aimed to compare the Macintosh DL and McGrath VL in terms of the glottic image quality, intubation success, intubation time, hemodynamic response after intubation, and complications in bariatric surgery patients.Material and methods: After obtaining approval by the ethics committee and receiving informed consent, we recorded the demographic and physical data of patients undergoing bariatric surgery. Patients were divided into 2 groups: Group M was intubated with the Macintosh DL, and Group V was intubated with the McGrath VL. …

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Avascular Necrosis Less Frequently Found In Systemic Lupus Erythematosus Patients With The Use Of Alternate Day Corticosteroid, İsmai̇l Doğan, Umut Kalyoncu, Levent Kiliç, Ali̇ Akdoğan, Ömer Karadağ, Sedat Ki̇raz, Şazi̇ye Şule Apraş Bi̇lgen, Ali̇ İhsan Ertenli̇ Jan 2020

Avascular Necrosis Less Frequently Found In Systemic Lupus Erythematosus Patients With The Use Of Alternate Day Corticosteroid, İsmai̇l Doğan, Umut Kalyoncu, Levent Kiliç, Ali̇ Akdoğan, Ömer Karadağ, Sedat Ki̇raz, Şazi̇ye Şule Apraş Bi̇lgen, Ali̇ İhsan Ertenli̇

Turkish Journal of Medical Sciences

Background/aim: Avascular necrosis (AVN) is the death of bone due to compromise of blood flow. The etiology of AVN is multifactorial; corticosteroid usage is the second most significant factor after trauma, and systemic lupus erythematosus (SLE) is the most common underlying disease. The objective of this study was to assess the factors of AVN in SLE patients. Materials and methods: The study included 127 patients with SLE who fulfilled 1997 American College of Rheumatology (ACR) revised criteria. Demographic data, age at SLE diagnosis, disease duration, disease activity, body mass index, clinical findings, antiphospholipid syndrome, steroid usage, dose and duration, comorbid …

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Reconstruction Of Complex Shallow Defects Of The Extremities With Free Serratus Musculofascial Flap*, Hakan Çi̇nal, Ensar Zafer Barin, Murat Kara, Kerem Yilmaz, Harun Karaduman, İhti̇şam Zafer Cengi̇z, Önder Tan Jan 2020

Reconstruction Of Complex Shallow Defects Of The Extremities With Free Serratus Musculofascial Flap*, Hakan Çi̇nal, Ensar Zafer Barin, Murat Kara, Kerem Yilmaz, Harun Karaduman, İhti̇şam Zafer Cengi̇z, Önder Tan

Turkish Journal of Medical Sciences

Background/aim: Thin and flexible flaps are needed for the repair of extremity tissue defects. Serratus fascia flaps are the most suitable options. There are only a few case reports and case series in the literature. We have aimed to increase the success rate by taking the serratus fascia flaps together with some muscle tissue for the repair of extremity tissue defects. Materials and methods: Between 2006 and 2015, 12 free serratus musculofascial flaps (FSMFFs) were transferred to 11 patients (8 males, 3 females) who had tissue shallow defects of the extremities due to different etiologic factors. The mean age was …

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Effects Of The Online Computerized Cognitive Training Program Beynex On The Cognitive Tests Of Individuals With Subjective Cognitive Impairment And Alzheimer's Disease On Rivastigmine Therapy, Ni̇lgün Çinar, Türker Ahmet Hasan Şahi̇ner Jan 2020

Effects Of The Online Computerized Cognitive Training Program Beynex On The Cognitive Tests Of Individuals With Subjective Cognitive Impairment And Alzheimer's Disease On Rivastigmine Therapy, Ni̇lgün Çinar, Türker Ahmet Hasan Şahi̇ner

Turkish Journal of Medical Sciences

Background/aim: Clinical trials conducted on the efficacy of computerized cognitive training (CCT) programs have not led to any important breakthroughs. CCT is a safe and inexpensive approach, but its efficacy in patients on rivastigmine therapy has not been evaluated. This study aims to compare effects of CCT and examines rivastigmine to determine whether CCT has any further contributions to make. Materials and methods: Sixty individuals with subjective memory complaint (SCI) and 60 individuals with early stage Alzheimer's dementia (AD) were subjected to the Montreal Cognitive Assessment (MoCA), Cambridge Cognition (CANTAB tests: MOT, PRM, DMS, SWM, PAL, RTI), and Bayer-ADL. After …

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