Open Access. Powered by Scholars. Published by Universities.®

Medical Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

1998

Discipline
Institution
Keyword
Publication
Publication Type

Articles 31 - 60 of 200

Full-Text Articles in Medical Sciences

Enhancement Of Atp Levels And Glucose Metabolism During An Infection By Chlamydia: Nmr Studies Of Living Cells, David M. Ojcius, H. Degani, Joel Mispelter, Alice Dautry-Varsat Mar 1998

Enhancement Of Atp Levels And Glucose Metabolism During An Infection By Chlamydia: Nmr Studies Of Living Cells, David M. Ojcius, H. Degani, Joel Mispelter, Alice Dautry-Varsat

All Dugoni School of Dentistry Faculty Articles

The Chlamydia species are obligate intracellular bacteria that proliferate only within the infected cell. Since the extracellular bacteria are metabolically inert and there are no cell-free systems for characterizingChlamydia metabolism, we studied metabolic changes related to ATP synthesis and glycolysis in HeLa cells infected withChlamydia psittaci during the course of the 2-day infection cycle using noninvasive 31P and 13C NMR methods. We find that the infection stimulates ATP synthesis in the infected cell, with a peak of ATP levels occurring midway through the infection cycle, when most of the metabolically active bacteria are proliferating. The infection also stimulates synthesis of …

Go to article

Chlamydia Trachomatis Infection In The Female Reproductive Tract Of The Rat: Influence Of Progesterone On Infectivity And Immune Response, Charu Kaushic, Andrew D. Murdin, Brian J. Underdown, Charles R. Wira Mar 1998

Chlamydia Trachomatis Infection In The Female Reproductive Tract Of The Rat: Influence Of Progesterone On Infectivity And Immune Response, Charu Kaushic, Andrew D. Murdin, Brian J. Underdown, Charles R. Wira

Dartmouth Scholarship

As the most common cause of sexually transmitted disease in women, chlamydial infections can lead to pelvic inflammatory disease, infertility, and ectopic pregnancy. To better understand the role played by sex hormones in modulating the immune response of the genital tract to microbial infections, we have developed a rat model to study Chlamydia trachomatis infection. Inbred female Lewis rats were primed with progesterone and inoculated by intrauterine instillation of C. trachomatis (mouse pneumonitis strain MoPn) into each uterine horn. When infected animals were examined for the presence of chlamydial antigens 14 days postinfection, both the uterus and vagina were found …

Go to article

Subcellular Localization Of Mineralocorticoid Receptors In Living Cells: Effects Of Receptor Agonists And Antagonists, Géza Fejes-Tóth, David Pearce, Anikó Náray-Fejes-Tóth Mar 1998

Subcellular Localization Of Mineralocorticoid Receptors In Living Cells: Effects Of Receptor Agonists And Antagonists, Géza Fejes-Tóth, David Pearce, Anikó Náray-Fejes-Tóth

Dartmouth Scholarship

Results on the subcellular localization of the mineralocorticoid receptor (MR) have been controversial. To determine the subcellular distribution and trafficking of the MR in living cells after binding of agonists and antagonists, we expressed a MR-green fluorescent protein (GFP) chimera in mammalian cells lacking endogenous MR. The GFP-tagged MR (GFP-MR) remained transcriptionally active, as determined in cotransfection experiments with the MR-responsive reporter, TAT3-LUC. The subcellular localization of GFP-MR was monitored by fluorescence time-lapse microscopy. In the absence of hormone, MR was present both in the cytoplasm and nucleus. Aldosterone induced a rapid nuclear accumulation of the MR. Aldosterone-bound GFP-MR was …

Go to article

Fornix Lesions Can Facilitate Acquisition Of The Transverse Patterning Task: A Challenge For "Configural" Theories Of Hippocampal Function., T J Bussey, E Clea Warburton, J P Aggleton, J L Muir Feb 1998

Fornix Lesions Can Facilitate Acquisition Of The Transverse Patterning Task: A Challenge For "Configural" Theories Of Hippocampal Function., T J Bussey, E Clea Warburton, J P Aggleton, J L Muir

Brain and Mind Institute Researchers' Publications

Configural theories of hippocampal function predict that hippocampal dysfunction should impair acquisition of the transverse patterning task, which involves the concurrent solution of three discrimination problems: A+ versus B-; B+ versus C-; and C+ versus A-. The present study tested this prediction in rats using computer-graphic stimuli presented on a touchscreen. Experiment 1 assessed the effects of fornix lesions when the three problems were introduced sequentially (phase 1: A+ vs B-; phase 2: A+ vs B-, B+ vs C-; phase 3: A+ vs B-, B+ vs C-, C+ vs A-). Fornix lesions significantly facilitated acquisition of the complete transverse patterning …

Go to article

Vasodilators Activate Erythrocyte K-Cl Cotransport, Norma C. Adragna, H. Ahmed, Peter K. Lauf Feb 1998

Vasodilators Activate Erythrocyte K-Cl Cotransport, Norma C. Adragna, H. Ahmed, Peter K. Lauf

Pharmacology and Toxicology Faculty Publications

No abstract provided.

Go to article

Investigation Of The Roles Of Toxin-Coregulated Pili And Mannose-Sensitive Hemagglutinin Pili In The Pathogenesis Of Vibrio Cholerae O139 Infection, Carol O. Tacket, Ronald K. Taylor, Genevieve Losonsky, Yu Lim Feb 1998

Investigation Of The Roles Of Toxin-Coregulated Pili And Mannose-Sensitive Hemagglutinin Pili In The Pathogenesis Of Vibrio Cholerae O139 Infection, Carol O. Tacket, Ronald K. Taylor, Genevieve Losonsky, Yu Lim

Dartmouth Scholarship

In this study, adult volunteers were fed tcpA and mshA deletion mutants of V. cholerae O139 strain CVD 112 to determine the role of toxin-coregulated pili (TCP) and mannose-sensitive hemagglutinin (MSHA) in intestinal colonization. Eight of 10 volunteers who received CVD 112 or CVD 112 ΔmshA shed the vaccine strains in their stools; the geometric mean peak excretion for both groups was 1.4 × 105 CFU/g of stool. In contrast, only one of nine recipients of CVD 112 ΔtcpA shed vibrios in his stool (P < 0.01); during the first 24 h after inoculation, 3 × 102 CFU/g was recovered from this volunteer. All recipients of CVD …

Go to article

A Vacuolar V–T-Snare Complex, The Predominant Form In Vivo And On Isolated Vacuoles, Is Disassembled And Activated For Docking And Fusion, Christian Ungermann, Benjamin J. Nichols, Hugh R. B. Pelham, William Wickner Jan 1998

A Vacuolar V–T-Snare Complex, The Predominant Form In Vivo And On Isolated Vacuoles, Is Disassembled And Activated For Docking And Fusion, Christian Ungermann, Benjamin J. Nichols, Hugh R. B. Pelham, William Wickner

Dartmouth Scholarship

Homotypic vacuole fusion in yeast requires Sec18p (N-ethylmaleimide-sensitive fusion protein [NSF]), Sec17p (soluble NSF attachment protein [alpha-SNAP]), and typical vesicle (v) and target membrane (t) SNAP receptors (SNAREs). We now report that vacuolar v- and t-SNAREs are mainly found with Sec17p as v-t-SNARE complexes in vivo and on purified vacuoles rather than only transiently forming such complexes during docking, and disrupting them upon fusion. In the priming reaction, Sec18p and ATP dissociate this v-t-SNARE complex, accompanied by the release of Sec17p. SNARE complex structure governs each functional aspect of priming, as the v-SNARE regulates the rate of Sec17p release and, …

Go to article

The Effect Of Tape And Neoprene Ankle Supports On Balance In Athletes With Injured Ankles, Tara Michelle Gerlach Jan 1998

The Effect Of Tape And Neoprene Ankle Supports On Balance In Athletes With Injured Ankles, Tara Michelle Gerlach

Theses, Dissertations and Capstones

Injuries to the ankle joint are among the most common in athletics (Feuerbach et al., 1994; Gross, 1987). As clinicians, it is important to investigate various factors which could potentially reduce the occurrence of ankle injuries. One such actors is an improvement in proprioception (Cox et al., 1993; Glencross & Thornton, 1994). A suggested method for improving proprioception in the ankle is application of an external support, such as tape or a brace (Feuerbach et al. , 1994; Karlsson & Andreasson, 1992 ) . This study compared the proprioceptive abilities of the ankle under three conditions: unsupported, taped, and using …

Go to article

Characterization Of The Promoter And Upstream Activation Sequences Of Sporulation-Specific Genes Spr1 (Ssg1) And Spr2 In Saccharomyces Cerevisiae, Sharmini S. Soosaithasan Jan 1998

Characterization Of The Promoter And Upstream Activation Sequences Of Sporulation-Specific Genes Spr1 (Ssg1) And Spr2 In Saccharomyces Cerevisiae, Sharmini S. Soosaithasan

Theses, Dissertations and Capstones

Sporulation is a developmental process in which temporally distinct sets of genes regulate the processes of meiosis and ascospore formation. Sporulation-specific genes are classified into early, middle, and late genes based on their peak time of expression during sporulation. Regulation of two late genes, SPR1 and SPR2, was studied. The function of SPR2 is unknown. Its regulatory region contains two Mid Sporulation Elements (MSE) repeated in tandem that are sufficient to confer sporulation-specific regulation to a CYCl-lacZ reporter. These sequences have UAS (upstream activation sequence) properties, as each 14 base pair element is sufficient to confer sporulation-specific regulation …

Go to article

Neurotransmitter Transport: Models In Flux, Michael Kavanaugh Jan 1998

Neurotransmitter Transport: Models In Flux, Michael Kavanaugh

Biomedical and Pharmaceutical Sciences Faculty Publications

Physiologists say that ions and neutral solutes can cross biological membranes via “transporters” and “channels.” We tend to think about the difference between transporters and channels in terms of gating mechanisms. Ion channels exhibit a wide range of selectivity properties and permeation rates, but their gating at the most basic level can be thought of in terms of a single barrier or gate acting as a switch. When the gate is closed, ions can’t permeate; when the gate is opened, a permeation pathway for ions allows flux, often at very high rates (up to 108/sec). Transporters and ion …

Go to article

Excitatory Amino Acid Transporters Of The Salamander Retina: Identification, Localization, And Function, Scott Eliasof, Jeffrey L. Arriza, Barbara H. Leighton, Michael Kavanaugh, Susan G. Amara Jan 1998

Excitatory Amino Acid Transporters Of The Salamander Retina: Identification, Localization, And Function, Scott Eliasof, Jeffrey L. Arriza, Barbara H. Leighton, Michael Kavanaugh, Susan G. Amara

Biomedical and Pharmaceutical Sciences Faculty Publications

The rapid re-uptake of extracellular glutamate mediated by a family of high-affinity glutamate transporter proteins is essential to continued glutamatergic signaling and neuronal viability, but the contributions of individual transporter subtypes toward cellular physiology are poorly understood. Because the physiology of glutamate transport in the salamander retina has been well described, we have examined the expression and function of glutamate transporter subtypes in this preparation. cDNAs encoding five distinct salamander excitatory amino acid transporter (sEAAT) subtypes were isolated, and their molecular properties and distributions of expression were compared. We report evidence that at least four distinct sEAAT subtypes are expressed …

Go to article

Molecular Determinant Of Ion Selectivity Of A (Na+ + K+)-Coupled Rat Brain Glutamate Transporter, Yumin Zhang, Annie Bendahan, Ruth Zarbiv, Michael Kavanaugh, Baruch I. Kanner Jan 1998

Molecular Determinant Of Ion Selectivity Of A (Na+ + K+)-Coupled Rat Brain Glutamate Transporter, Yumin Zhang, Annie Bendahan, Ruth Zarbiv, Michael Kavanaugh, Baruch I. Kanner

Biomedical and Pharmaceutical Sciences Faculty Publications

Glutamate transporters remove this neurotransmitter from the synaptic cleft by a two-stage electrogenic process, in which glutamate is first cotransported with three sodium ions and a proton. Subsequently, the cycle is completed by translocation of a potassium ion in the opposite direction. Recently, we have identified an amino acid residue of the glutamate transporter GLT-1 (Glu-404) that influences potassium coupling. We have now analyzed the effect of seven other amino acid residues in the highly conserved region surrounding this site. One of these residues, Tyr-403, also proved important for potassium coupling, because mutation to Phe (Y403F) resulted in an electroneutral …

Go to article

Cysteine Scanning Of The Surroundings Of An Alkali-Ion Binding Site Of The Glutamate Transporter Glt-1 Reveals A Conformationally Sensitive Residue, Ruth Zarbiv, Myriam Grunewald, Michael Kavanaugh, Baruch I. Kanner Jan 1998

Cysteine Scanning Of The Surroundings Of An Alkali-Ion Binding Site Of The Glutamate Transporter Glt-1 Reveals A Conformationally Sensitive Residue, Ruth Zarbiv, Myriam Grunewald, Michael Kavanaugh, Baruch I. Kanner

Biomedical and Pharmaceutical Sciences Faculty Publications

Glutamate transporters remove this transmitter from the extracellular space by cotransport with three sodium ions and a proton. The cycle is completed by translocation of a potassium ion in the opposite direction. Recently we have identified two adjacent amino acid residues of the glutamate transporter GLT-1 that influence potassium coupling. Using the scanning cysteine accessibility method we have now explored the highly conserved region surrounding them. Replacement of each of the five consecutive residues 396–400 by cysteine abolished transport activity but at several other positions the substitution is tolerated. One residue, tyrosine 403, was identified where cysteine substitution renders the …

Go to article

Gp120 Envelope Glycoproteins Of Human Immunodeficiency Viruses Competitively Antagonize Signaling By Coreceptors Cxcr4 And Ccr5, Navid Madani, Susan L. Kozak, Michael Kavanaugh, David Kabat Jan 1998

Gp120 Envelope Glycoproteins Of Human Immunodeficiency Viruses Competitively Antagonize Signaling By Coreceptors Cxcr4 And Ccr5, Navid Madani, Susan L. Kozak, Michael Kavanaugh, David Kabat

Biomedical and Pharmaceutical Sciences Faculty Publications

Signal transductions by the dual-function CXCR4 and CCR5 chemokine receptors/HIV type 1 (HIV-1) coreceptors were electrophysiologically monitored in Xenopus laevis oocytes that also coexpressed the viral receptor CD4 and a G protein-coupled inward-rectifying K+ channel (Kir 3.1). Large Kir 3.1-dependent currents generated in response to the corresponding chemokines (SDF-1α for CXCR4 and MIP-1α; MIP-1β and RANTES for CCR5) were blocked by pertussis toxin, suggesting involvement of inhibitory guanine nucleotide-binding proteins. Prolonged exposures to chemokines caused substantial but incomplete desensitization of responses with time constants of 5–7 min and recovery time constants of 12–19 min. CXCR4 and CCR5 exhibited heterologous …

Go to article

Arachidonic Acid Activates A Proton Current In The Rat Glutamate Transporter Eaat4, Anastassios V. Tzingounis, Chien-Liang Lin, Jeffrey D. Rothstein, Michael Kavanaugh Jan 1998

Arachidonic Acid Activates A Proton Current In The Rat Glutamate Transporter Eaat4, Anastassios V. Tzingounis, Chien-Liang Lin, Jeffrey D. Rothstein, Michael Kavanaugh

Biomedical and Pharmaceutical Sciences Faculty Publications

The excitatory amino acid transporter EAAT4 is expressed predominantly in Purkinje neurons in the rat cerebellum (1-3), and it participates in postsynaptic reuptake of glutamate released at the climbing fiber synapse (4). Transporter-mediated currents in Purkinje neurons are increased more than 3-fold by arachidonic acid, a second messenger that is liberated following depolarization-induced Ca2+ activation of phospholipase A2 (5). In this study we demonstrate that application of arachidonic acid to oocytes expressing rat EAAT4 increased glutamate-induced currents to a similar extent. However, arachidonic acid did not cause an increase in the rate …

Go to article

Macroscopic And Microscopic Properties Of A Cloned Glutamate Transporter/Chloride Channel, Jacques I. Wadiche, Michael Kavanaugh Jan 1998

Macroscopic And Microscopic Properties Of A Cloned Glutamate Transporter/Chloride Channel, Jacques I. Wadiche, Michael Kavanaugh

Biomedical and Pharmaceutical Sciences Faculty Publications

The behavior of a Cl− channel associated with a glutamate transporter was studied using intracellular and patch recording techniques in Xenopus oocytes injected with human EAAT1 cRNA. Channels could be activated by application of glutamate to either face of excised membrane patches. The channel exhibited strong selectivity for amphipathic anions and had a minimum pore diameter of ∼5Å. Glutamate flux exhibited a much greater temperature dependence than Cl− flux. Stationary and nonstationary noise analysis was consistent with a sub-femtosiemen Cl− conductance and a maximum channelPo ≪ 1. The glutamate binding rate was similar to estimates …

Go to article

Histochemical And Fluorescent Labelling Ofneurons Projecting To Nucleus Accumbens: Therelation To Pain Processing, Gülgün Kayalioğlu, Figen Gövsa, Vladaimir A. Maisky, Nuran Hari̇ri̇, Berrin Erdem, Yılmaz Şenyilmaz Jan 1998

Histochemical And Fluorescent Labelling Ofneurons Projecting To Nucleus Accumbens: Therelation To Pain Processing, Gülgün Kayalioğlu, Figen Gövsa, Vladaimir A. Maisky, Nuran Hari̇ri̇, Berrin Erdem, Yılmaz Şenyilmaz

Turkish Journal of Medical Sciences

This study was undertaken to examine the laminar distribution of spinotelencephalic tract neurons in the rat, by means of retrograde fluorescent labelling and to estimate the role of NADPH-diaphorase-reactive spinal cells as sources of spino-supraspinal pathways in the rat. The localization, size and shape of some neurons were similar in both labelling methods. Cells were mostly multipolar in the medial part of nucl. proprius, and fusiform and spindle-shaped in lamina I and X. It is suggested that some of the NADPH-d (+) neurons in the deep dorsal horn and lamina X are sources of a spino-supraspinal pathway to nucleus accumbens …

Go to article

Angiotensin Converting Enzyme Activity In Theserum, Lung, Liver And Kidney In Streptozotocin-Induced Diabetic Rats And Diabetic Nephropathy, Bilal Üstündağ, Mehmet Çay, İbrahim H. Özercan, Mustafa Naziroğlu, Necip İlhan Jan 1998

Angiotensin Converting Enzyme Activity In Theserum, Lung, Liver And Kidney In Streptozotocin-Induced Diabetic Rats And Diabetic Nephropathy, Bilal Üstündağ, Mehmet Çay, İbrahim H. Özercan, Mustafa Naziroğlu, Necip İlhan

Turkish Journal of Medical Sciences

To clarify the relationship between the alterations of the levels of angiotensin converting enzyme (ACE) and diabetic nephropathy, ACE activity in the lung, liver, kid-ney and serum were investigated in streptozotocin (STZ)-induced diabetic rats. The levels of serum ACE activity unchanged 3 days post STZ treatment but it was significantly an increase 12 and 30 days post STZ treatment in diabetic rats (p

Go to article

Pulmonary Effects Of Dexfenfluramine, Ferhan Candan, Melih Kaptanoğlu, Reyhan Egi̇lmez, Kasim Doğan, Metin Aksoy, Yücel Yalman, Ebuzer Bekar, Füsun Gülteki̇n Jan 1998

Pulmonary Effects Of Dexfenfluramine, Ferhan Candan, Melih Kaptanoğlu, Reyhan Egi̇lmez, Kasim Doğan, Metin Aksoy, Yücel Yalman, Ebuzer Bekar, Füsun Gülteki̇n

Turkish Journal of Medical Sciences

Dexfenfluramine is a variation of fenfluramine which is used for weight reduction. The aim of the study is to determine the hemodynamic and structural effects of this drug on pulmonary circulation. An experimintal study was carried out with New Zealand Rabbits. A control group (n=30) and an experimintal group (n=20) was constituted. A four-week normal diet for control group and dexfenfluramine plus normala diet for experimental group were applied. Body weights and pulmonary artery pressures of groups were recorded and lungs were collected for pathologic examination. In experimintal group; Dexfenfluramine raised systolic pulmonary artery pressures significantly (p0.05). Weight reduction was …

Go to article

The Effect Of Diclofenac Sodium On The Renalparenchyma During Complete Unilateral Ureteralobstruction Of The Rats, Cüneyt Turan, Olgun Kontaş, Ahmet Bekereci̇oğlu, Canan Kocaoğlu, Murat Alper, Mustafa Küçükaydin Jan 1998

The Effect Of Diclofenac Sodium On The Renalparenchyma During Complete Unilateral Ureteralobstruction Of The Rats, Cüneyt Turan, Olgun Kontaş, Ahmet Bekereci̇oğlu, Canan Kocaoğlu, Murat Alper, Mustafa Küçükaydin

Turkish Journal of Medical Sciences

An experimental study was designed to investigate the effect of diclofenac sodium (DS) on both renal parenchyma during complete unilateral ureteral obstruction. In 40 adult rats, left ureteropelvic junction were completely obstructed. Rats were divided into 4 equal groups and treated with cefoperazone (Group 2), DS (Group 3), cefoperazone and DS (Group 4) for one week postoperatively. No drug was given to Group 1 (control). Then, both kidneys of all rats were removed and examined histopathologically. The parenchymal thickness of left kid-neys were less than those of rights in all groups. Renal capsuli were moderately thickened in all obstructed kidneys. …

Go to article

Tumor Necrosis Factor-\Alpha And Interleukin-6 Inperitoneal Adhesion Formation, Mahmut Başoğlu, Ahmet Kiziltunç, Fatih Akçay, Sait Keleş, Cemal Gündoğdu, Durkaya Ören Jan 1998

Tumor Necrosis Factor-\Alpha And Interleukin-6 Inperitoneal Adhesion Formation, Mahmut Başoğlu, Ahmet Kiziltunç, Fatih Akçay, Sait Keleş, Cemal Gündoğdu, Durkaya Ören

Turkish Journal of Medical Sciences

This study was carried out to assess the role of tumor necrosis factor (TNF-\alpha) and interleukin-6 (IL-6 ) in plasma and peritoneal fluid in higher rates of adhesion formation following standard bowel injury. Forty-five albino rabbits were divided into three equal groups. Blood was obtained from all the rabbits preoperatively. All the rabbits were subjected to a laparotomy. In group 1(control group), the peritoneal cavity was irrigated with normal saline. In group 2 the cecal serosa was abraded, while the rabbits in group 3 had a resection in small bowel of 2 cm. A peritoneal catheter was placed in all …

Go to article

Increased Serum Ca 72-4 Levels In Patientswith Gastrointestinal Carcinoma, Mahmut Başoğlu, Ahmet Kiziltunç, Fatih Akçay, Cemal Gündoğdu, İbrahim Kavak, Durkaya Ören Jan 1998

Increased Serum Ca 72-4 Levels In Patientswith Gastrointestinal Carcinoma, Mahmut Başoğlu, Ahmet Kiziltunç, Fatih Akçay, Cemal Gündoğdu, İbrahim Kavak, Durkaya Ören

Turkish Journal of Medical Sciences

This study is an evaluation of serum levels in the tumor markers CA 19-9 and CA 72-4 in gastric cancer patients in preoperative, postoperative and follow-up periods. These tumor markers were measured in 35 patients with primary gastric carcinoma (28 advanced stage, 7 early stage), 27 with benign gastric disease and 20 healthy control subjects. Serum CA 72-4 levels were found to have increased (>6.7kU/l) in 16 (14 with advanced stage, 2 with early stage) patients with primary gastric carcinoma. Serum CA 19-9 levels were elevated (>22kU/l) in 9 patients with primary gastric carcinoma (8 with advanced stage, …

Go to article

Clinical Utility Of Lymphocyte Cross-Matchingafter Renal Transplantation, Olcay Yeği̇n, Gültekin Süleymanlar, Nezih Oygür, Mesut Coşkun, Ayşe Savaş, Nilgün Keçeci̇oğlu, Tuncer Karpuzoğlu Jan 1998

Clinical Utility Of Lymphocyte Cross-Matchingafter Renal Transplantation, Olcay Yeği̇n, Gültekin Süleymanlar, Nezih Oygür, Mesut Coşkun, Ayşe Savaş, Nilgün Keçeci̇oğlu, Tuncer Karpuzoğlu

Turkish Journal of Medical Sciences

One of the most important obstacles in renal transplantation is the rejection phenomenon. In spite of the developments in medical technology and immunology, early diagnosis of rejection and specific immunosuppression of the immune attack against the graft have not yet been totally accomplished. Lymphocyte cross-matching (LCM), a test to detect the presence of preformed antibodies in the donor against the recipient, is a practical and cheap method and is performed at almost all renal transplantation centers before transplantation. In this study, we searched for the relation between the posttransplant LCM status and graft survival. LCM was positive in 7 patients …

Go to article

Glycoprotein Iib/Iiia Inhibitors In Acute Coronarysyndromes: A New Paradigm In Cardiology, Mehmet Ağirbaşli, David M. Kerins Jan 1998

Glycoprotein Iib/Iiia Inhibitors In Acute Coronarysyndromes: A New Paradigm In Cardiology, Mehmet Ağirbaşli, David M. Kerins

Turkish Journal of Medical Sciences

No abstract provided.

Go to article

Treatment Of The Multiple Small Stone Particles(Steinstrasse) In The Lover Ureter After Theextracorporeal Shockwave Lithotripsy (Eswl)Treatment, Nihat Satar, Şaban Doran, Reha Özkeçeli̇, R. K. Türkyilmaz Jan 1998

Treatment Of The Multiple Small Stone Particles(Steinstrasse) In The Lover Ureter After Theextracorporeal Shockwave Lithotripsy (Eswl)Treatment, Nihat Satar, Şaban Doran, Reha Özkeçeli̇, R. K. Türkyilmaz

Turkish Journal of Medical Sciences

ESWL is an effective and noninvasive method of treatment for patients with urinary stones. However, especially in the treatment of larger stones impact of the small stone particles in the lower ureter (steinstrasse) is a serious complication that affects the result of the procedure. If the renal unit has not been catheterized before the ESWL procedure, removal of these particles by open surgical or endoscopic intervention within a very short time is mandatory. A total of 1576 renal unit were treated by ESWL with the Dornier MPL 9000 lithotripter from April 1991 to April 1995. Steinstrasse was observved in 81 …

Go to article

Women With Elevated Second Trimester Humanchorionic Gonadotropin Level Are At Increasedrisk For Preeclampsia, Aysel Kabukçu, S. Lütfü Önderoğlu, Yahya Laleli̇, Tekin Durukan Jan 1998

Women With Elevated Second Trimester Humanchorionic Gonadotropin Level Are At Increasedrisk For Preeclampsia, Aysel Kabukçu, S. Lütfü Önderoğlu, Yahya Laleli̇, Tekin Durukan

Turkish Journal of Medical Sciences

Objective: Our purpose was to determine whether unexplained elevations in maternal serum human chorionic gonadotropin (hCG)in the second trimester is associated with an increased risk of preeclampsia. Methods: Between April 1992 to April 1995, 610 pregnant women undergoing second trimester triple marker screening for Down's syndrome who were delivered at our institution were included to the study. 81 women with an hCG level greater than 2.0 multiples of median (MOM) served as the study group and 481 women with hCG levels

Go to article

A Study Of T And B Lymphocytes And Nk Cellsin Healthy And Preeclamptic Pregnant Women, Salih Çeti̇ner, Akgün Yaman, İsmail H. Dündar, Gülay Logoğlu, Pauline Aksungur Jan 1998

A Study Of T And B Lymphocytes And Nk Cellsin Healthy And Preeclamptic Pregnant Women, Salih Çeti̇ner, Akgün Yaman, İsmail H. Dündar, Gülay Logoğlu, Pauline Aksungur

Turkish Journal of Medical Sciences

There are various theories concerning the etiology of preeclampsia and eclampsia. According to one of these, the immunologic mechanism may play a role. The aim of this study was to determine whether or not T and B Iymphocytes and NK cells, which are important in cellular immunity, play a role in the development of this disease. We determined the percentage of the subgroups CD2, CD4 and CD8 of the T Iymphocytes, CD20 of the B Iymphocytes and CD56 of the NK cells in 26 preeclamptic pregnant women in their 3rd trimestir. All of these elements were olso investigated in 13 …

Go to article

The Determination Of Salivary Zinc Levelfollowing Delivery From Zinc Containingtoothpaste, Atilla Özdemi̇r, Ahmet Sayal, Eralp Akça, Ahmet Aydin Jan 1998

The Determination Of Salivary Zinc Levelfollowing Delivery From Zinc Containingtoothpaste, Atilla Özdemi̇r, Ahmet Sayal, Eralp Akça, Ahmet Aydin

Turkish Journal of Medical Sciences

The effect of zinc salts is defined by several studies. The aim of this study is to investigate how the short period toothbrushing with equal volumes of a toothpaste containing 0.75% zinccitrate effects the salivary zinc levels over a period of 7 hours. In our study a significant increase in zinc measurements was observed 5 minutes after toothbrushing. Although 7 th hour measurements were higher than 0 hour measurements; these values were found approximately similar to intial control measurements. This result shows that the amount of zinc passed by toothpaste to saliva completely disappeared at the end of 7 th …

Go to article

The Auricular Cartilage Graft Fixation With Butyl2-Cyanocrylate, Fehmi Döner, İbrahim Sari, Aziz Öztürk, R. Murat Karaşen, Muharrem Bi̇ti̇ren, Yavuz Sütbeyaz Jan 1998

The Auricular Cartilage Graft Fixation With Butyl2-Cyanocrylate, Fehmi Döner, İbrahim Sari, Aziz Öztürk, R. Murat Karaşen, Muharrem Bi̇ti̇ren, Yavuz Sütbeyaz

Turkish Journal of Medical Sciences

Cartilage grafts are widely used in maxillo-facial reconstruction operations. There are some difficulties of conventional suture techniques in these operations such as long operation time, mobilization, shifting, and implantation or fixation of small pieces of cartilage. Therefore the advantages of a tissue adhesive over conventional suture techniques became evident in these operations. Butyl 2-Cyanoacrylate (B2-CA) is one of the least histotoxic cyanoacrylate derivatives and is used as a tissue adhesive. In this study, B2-CA was compared with conventional suture techniques in securing rabbit auricular cartilage autografts. Sutures were used in the left control ears and B2-CA was used in the …

Go to article

Evaluation Of Reproducibility Of The Peripheraltissues In Edentulous Patients, Ufuk Hasanrei̇soğlu, Ayhan Gürbüz, A. Nehir Özden, Fuat Kesi̇m Jan 1998

Evaluation Of Reproducibility Of The Peripheraltissues In Edentulous Patients, Ufuk Hasanrei̇soğlu, Ayhan Gürbüz, A. Nehir Özden, Fuat Kesi̇m

Turkish Journal of Medical Sciences

The effect of different techniques and materials on peripheral shaping of the complete denture impressions were investigated by stereophotogrammetric method. Six impressions were taken from each of the 20 edentulous patients by using two different techniques and three impression materials. A non-metric camera was used to produce stereo paired photographs of each model. The measurements were made at the buccal vestibule regions, labial vestibule regions and labial frenilum region on 120 casts. When buccal vestibule regions were evaluated no statistically significant difference was found between double phase and mono phase impression materials.

Go to article

First Prev Next Last