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Articles 4801 - 4830 of 4871
Full-Text Articles in Medical Sciences
Plasma Fibronectin And Urineglycosaminoglycane Levels In Rheumatic Diseases, Nuriye Mete, Mahmut Mete, İ. Hakkı Öztürk, Leyla Çolpan
Plasma Fibronectin And Urineglycosaminoglycane Levels In Rheumatic Diseases, Nuriye Mete, Mahmut Mete, İ. Hakkı Öztürk, Leyla Çolpan
Turkish Journal of Medical Sciences
In this study, plasma fibronectin and urine glycosaminoglycane levels were determined spectrophotometrically in 20 Rheumatoid arthritis, 10 Ankilosing spondilites, 22 osteoarthrosis and 21 healthy control subjects. The mean levels of Fibronectin (\mug/ml) were 413.3±97 in patients with rheumatoid arthritis, 325.5±93.5 in ankilosing spondilites, 439.1±120.3 in osteoarthrosis and 302.2±60.1 in the control group. The ratio of urine glycosaminoglycan excretion to creatinine (g/mol) was 4.52±2.64 in patients with rheumatoid arthritis, 4.18±1.52 in patients with ankilosing spondilites, 2.72±1.19 in osteoarthrosis and 2.21±1.02 in the control group. Plasma Fibronectin levels were significantly higher in rheumatoid arthritis and osteoarthrosis when compared to the control group …
Determination Of The Prevalence Of Latexsensitivity By In Vivo And In Vitromethods Among Hospital Employees Andallergic Patients, Ayşe Füsun Kalpaklioğlu, Lütfü Gürbüz, Zeynep Misirligi̇l
Determination Of The Prevalence Of Latexsensitivity By In Vivo And In Vitromethods Among Hospital Employees Andallergic Patients, Ayşe Füsun Kalpaklioğlu, Lütfü Gürbüz, Zeynep Misirligi̇l
Turkish Journal of Medical Sciences
Background: Latex has been documented as causing immediate hypersensitivity reactions ranging from contact urticaria to severe anaphylaxis. The prevalence of latex allergy appears to be higher in certain risk groups due to increased exposure or to an increased intrinsic predilection for atopy. The purpose of the present study was both to assess latex sensitivity in a large group of allergic patients and in hospital emyloyees and to evaluate the relationship between latex sensitivity and skin prick test (SPT) responses to fruits as well as inhalant allergens. Methods: This study was designed prospectively in a randomized manner. SPTs were performed and …
A Probable Case Of Men1 Syndrome Presentingwith Intractable Peptic Ulcer Disease Andepisodic Confusion, Şükrü Palanduz, Cemil Taşçioğlu, Nilgün Erten, Mehmet Akif Karan, Kıvanç Çefle, Kerim Güler, Oğuz Öztürk, Şükrü Öztürk
A Probable Case Of Men1 Syndrome Presentingwith Intractable Peptic Ulcer Disease Andepisodic Confusion, Şükrü Palanduz, Cemil Taşçioğlu, Nilgün Erten, Mehmet Akif Karan, Kıvanç Çefle, Kerim Güler, Oğuz Öztürk, Şükrü Öztürk
Turkish Journal of Medical Sciences
No abstract provided.
Antrhrax Meningitis, Birdal Yorgancigi̇l, Erdoğan Sevük, Muzaffer Aydemi̇r, Mustafa Demi̇rci̇, Mehmet Doğanay
Antrhrax Meningitis, Birdal Yorgancigi̇l, Erdoğan Sevük, Muzaffer Aydemi̇r, Mustafa Demi̇rci̇, Mehmet Doğanay
Turkish Journal of Medical Sciences
No abstract provided.
Characterisation Of A Polyclonal Antiserumagaints Ubiquitin And Its Use In The Investigationof Ubiquitin Conjugate Distribution In Normaland Stressed 3t3-Li Cells, İbrahim Pi̇ri̇m
Turkish Journal of Medical Sciences
Antiserum against ubiquitin was used to identify ubiquitin conjugates in 3T3- LI cells, and to investigate changes in the amount and distribution of these conjugates in cells subjected to stress. Stress was induced by incubation with canavanine, an amino acid analogue, and by exposure of cells to temperatures of 43°C (heat shock). SDS-PAGE, followed by immunoblotting, produced no observable change in ubiquitin conjugation with the canavanine as used in this protocol.Heat shock, in a variety of different exposure protocols, appeared to produce an increase in a wide spectrum of ubiquitin conjugates of molecular weight>70kd. The conjugates wereresent in the …
Distribution Of Tamoxifen In Rat Tissues Duringsteady-State Treatment, Ayşe Kafkasli, Erkan Ünlenen, Beyhan Demi̇rhan, Saim Yoloğlu
Distribution Of Tamoxifen In Rat Tissues Duringsteady-State Treatment, Ayşe Kafkasli, Erkan Ünlenen, Beyhan Demi̇rhan, Saim Yoloğlu
Turkish Journal of Medical Sciences
Tamoxifen citrate (TAM), a nonsteroidal antiestrogen, is a drug of choice in the endocrine treatment for all stages of breast cancer in both pre and postmenopausal patients. The tissue distrubution of TAM alone and combined with medroxyprogesterone acetate (MPA) following long-term p.o. administration in immature rats is investigated in the present study. The highest consentrations of TAM has been found in the hypophysis in both groups. TAM consentrations were effected by MPA treatment in the liver and kidneys.
The Effect Of Zinc On Microbial Growth, Selahattin Atmaca, Kadri Gül, Ramazan Çi̇çek
The Effect Of Zinc On Microbial Growth, Selahattin Atmaca, Kadri Gül, Ramazan Çi̇çek
Turkish Journal of Medical Sciences
The antibacterial activity of zinc acetate against Staphylococcus auerus, Staphylococcus epidermidis and Pseudomonas aeruginosa isolates was measured in Mueller-Hinton broth containing different amounts of zinc acetate using spectrophotometry. Staphylococcus auerus, Staphylococcus epidermidis and Pseudomonas aeruginosa isolates were inhibited by zinc acetate (p
Purification Of Casein Kinase Ii From Lung Tissueand Kinetic Evaluations With Polyamines Andmyc-Oncoprotein, Nesrin Gündoğus-Özcanli, Wayne E. Criss
Purification Of Casein Kinase Ii From Lung Tissueand Kinetic Evaluations With Polyamines Andmyc-Oncoprotein, Nesrin Gündoğus-Özcanli, Wayne E. Criss
Turkish Journal of Medical Sciences
The overall goal of this study was to seek molecular linkages between polyamines, casein kinase II, and the myc oncoprotein by using a cell-free, highly purified enzyme kinetic analysis. Casein kinase II (CKII) was purified from sheep lung tissue by using an original 3-column/3-day set of procedures (DEAE cellulose, Sepharose 6L-4B, and poly-L- lysine agrose affinity chromotographies). CKII was purified approximately 550-fold with a recovery of near 40% and a final specific activity of about 250,000 pmol of phosphorylated protein substrate (casein)/min/mg of enzyme protein. Kinetic evaluations with the purified CKII using Mg-GTP as a phosphate donor, etiher casein or …
A New Phenotype In The Phosphoğlucomutase1 (Pgm1) System, Pgm1*W32, E. Ferda Perçi̇n, A. İsmihan Göze
A New Phenotype In The Phosphoğlucomutase1 (Pgm1) System, Pgm1*W32, E. Ferda Perçi̇n, A. İsmihan Göze
Turkish Journal of Medical Sciences
Red cell phosphOĞLUcomutase 1 (PGM1) enzyme, which is a phosphotransferase, has 3 common and 31 rare phenotypes. In this study, we have identified a new phenotype for this enzyme which has not been reported previously using cellulose acetate electrophoresis technique. This phenotype has also been identified for the first time for Turkish population and called PGM1*W32.
The Seminal Fluid Isoenzyme Ldh-C4 In Infertilemen, Meral Fadiloğlu, Cevval Ulman, Banu Önvural, Ata Önvural
The Seminal Fluid Isoenzyme Ldh-C4 In Infertilemen, Meral Fadiloğlu, Cevval Ulman, Banu Önvural, Ata Önvural
Turkish Journal of Medical Sciences
In order to determine the seminal activity of LDH-C4 and to investigate its correlation with other fertility indexes, we studed total LDH, total CK avtivities, and LDH-C4 in relation to sperm count, motility and sperm motility index (SMI). SMI is the measurement of electro-optical fluctuations caused by motile sperm. Total LDH and total CK were determined with a Technicon RA 1000 analyser, and LDH isoenzymes with Helena Lab. isoenzyme kits. The results in 23 infertile men showed that LDH-C4 activity was either absent (4 cases), or decreased (19 cases). LDH-C4 showed a positive correlation with total LDH, sperm count and …
Translocation 13;14 Associated Withmyelodsplastic Syndrome In Down's Syndrome, Gül Sapmaz, Ferda Özkinay, Hasan Yüksel, Cihangir Özkinay, Figen Akdeni̇zli̇oğlu, Nejat Topçuoğlu, Şenay Öztop
Translocation 13;14 Associated Withmyelodsplastic Syndrome In Down's Syndrome, Gül Sapmaz, Ferda Özkinay, Hasan Yüksel, Cihangir Özkinay, Figen Akdeni̇zli̇oğlu, Nejat Topçuoğlu, Şenay Öztop
Turkish Journal of Medical Sciences
No abstract provided.
The Efficacy Of L-Carnitine Treatment Indilated Cardiomyopathy, Emir Dönder, Ramiz Çolak, Aziz Karaoğlu, Oğuz Ayhan, Yusuf Özkan
The Efficacy Of L-Carnitine Treatment Indilated Cardiomyopathy, Emir Dönder, Ramiz Çolak, Aziz Karaoğlu, Oğuz Ayhan, Yusuf Özkan
Turkish Journal of Medical Sciences
This study was carried out to investigate clinical effects of treatment with the supplementation of L-carnitine in cases with dilated cardiomyopathy. B Mode, M-Mode, and continuous Doppler echocardiograms were applied with standard techniques in totally 28 patients assessed before treatment with L-carnitine and at the 1 st , 5 th , 10 th , 30 th , and 60 th days of the treatment. The diameter of the left ventricular endsystolic and end-diastolic have decreased with L-carnitine treatment (p
Metabolic Effects Of Isradipine In Normotensiveniddm Patients With Microalbuminuria, Tevfik Sabuncu, Hüseyin Vural, Mahmut Dalmaz, Yaşar Nazligül, Abdurrahim Koçyi̇ği̇t, Özcan Erel, Şenel Avci
Metabolic Effects Of Isradipine In Normotensiveniddm Patients With Microalbuminuria, Tevfik Sabuncu, Hüseyin Vural, Mahmut Dalmaz, Yaşar Nazligül, Abdurrahim Koçyi̇ği̇t, Özcan Erel, Şenel Avci
Turkish Journal of Medical Sciences
The aim of this study was to determine whether isradipine affects microalbuminuria and other biochemical parameters related to glucose and lipid metabolisms. 18 subjects, 40 to 73 years of age, with NIDDM for 0 to 21 years, blood pressure²140/90 mmHg in the absence of antihypertensive treatment, and persistent urinary albumin excretion rate (UAER) 30 to 300 mg/day, received sustained-release (SRO) formulation isradipine at dosages of 5 mg once daily for 3 months. The effects of isradipine on microalbuminuria, fasting plasma glucose, plasma lipids, plasma creatinin, uric acid, C-peptide, insulin, HbA 1c , fructosamine, systolic and diastolic blood pressure and heart …
The Effects Of Ace Inhibition On Central Retinalartery In Diabetes Mellitus, Serdal Çelebi̇, Hüseyin Çeli̇ker, Harika Çelebi̇, Ülkü Ö. Çeli̇ker
The Effects Of Ace Inhibition On Central Retinalartery In Diabetes Mellitus, Serdal Çelebi̇, Hüseyin Çeli̇ker, Harika Çelebi̇, Ülkü Ö. Çeli̇ker
Turkish Journal of Medical Sciences
Angiotensin converting enzyme (ACE) inhibitors have been known to inhibit the effects of angiotensin II which increases the vascular resistance. In this study, we studied the acute effects of a single dose of 2.5 mg oral cilazapril, ACE inhibitor on blood flow velocity and vascular resistance parameters of central retinal artery (CRA) by color Doppler ultrasonography in 17 patients with nonproliferative diabetic retinopathy (NPDR) and compared the effects of the drug with a placebo group including 17 patients with nonproliferative diabetic retinopathy. After cilazapril medication, peak systolic blood flow velocity of central retinal artery didn't change, while peak diastolic and …
Changes In Blood Antioxidant Status And Lipidperoxidation Following Distance Running, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Sermet, Mukadder Atmaca, Yüksel Koçyi̇ği̇t
Changes In Blood Antioxidant Status And Lipidperoxidation Following Distance Running, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Sermet, Mukadder Atmaca, Yüksel Koçyi̇ği̇t
Turkish Journal of Medical Sciences
To examine the effects of increased O 2 utilization on blood antioxidant status and lipid peroxidation, ten trained male athletes took part in a 20 km distance race. Venous blood samples were removed before and immediately after completion of the half-marathon. Plasma creatine kinase (CK) activity, an index of muscle damage, increased (p
Effect Of Selenium On "Low T_3 Syndrome" Inhepatic Failure, Emir Dönder, Mehmet Çay, Necip İlhan, Giyasettin Baydaş, Mustafa Naziroğlu
Effect Of Selenium On "Low T_3 Syndrome" Inhepatic Failure, Emir Dönder, Mehmet Çay, Necip İlhan, Giyasettin Baydaş, Mustafa Naziroğlu
Turkish Journal of Medical Sciences
Triiodothyronine occurs especially in 5'-monodeiodination of thyroxin in peripheral tissues. Deiodination of thyroxin mainly occurs in the liver. The enzyme which catalyzes this reaction is a seleno-enzyme. Deiodinase enzyme activity and the triiodothyronine level decrease in selenium deficiency. After the occurrence of chronic hepatic failure by carbon tetrachloride in rats, we gave sodium selenite to these rats. Then, we tried to evaluate the changes in thyroid hormone levels. Liver function tests, thyroxin and triiodothyronine levels, and hepatic 5'-deiodinase and glutathione peroxidase enzyme activities were measured. Triiodothyronine levels in the carbon tetrachloride group and carbon tetrachloride + selenium group were significantly …
Effects Of Silver On Humans Living Near A Silvermine, Burhanettin Işikli, Temur Ali Demi̇r, Ünal Özelmas, Asiye Berber
Effects Of Silver On Humans Living Near A Silvermine, Burhanettin Işikli, Temur Ali Demi̇r, Ünal Özelmas, Asiye Berber
Turkish Journal of Medical Sciences
The aim of this study was to determine the effects of silver mining on individuals living in Gümüs, a province of Kütahya in Turkey, which is located near a silver mine. For this purpose, two groups of subjects were chosen. The first group consisted of 59 people (n=59) above the age of 30 who had been potentially exposed to silver. The second group, which formed the control group of the study, were the same age as the first group (p>0.05) but had not been exposed to silver manufacturing, and lacked a history of silver medication. Blood, urine, hair, soil, …
Association Of Hla Type With Pseudoexfoliationof The Lens Capsule, Hakkı Doğan, Türkan Patiroğlu, Engin Baykal, Kuddusi Erkiliç
Association Of Hla Type With Pseudoexfoliationof The Lens Capsule, Hakkı Doğan, Türkan Patiroğlu, Engin Baykal, Kuddusi Erkiliç
Turkish Journal of Medical Sciences
Exfoliation of the lens capsule is asymptomatic but it is associated with the development of glaucoma and blindness if undetected and untreated. The occurrence of exfoliation varies widely in different countries where the population is ethnically homogeneous. It is suggested that both genetic and environmental influences are important in the development of exfoliative syndrome (ES). This study was carried out to determine if there was any relation between ES and HLA. HLA antigen types were determined in 45 patients with exfoliative syndrome. We found a strong association between HLA-A2, HLA-DR5, HLA B21 and HLA-DR7 and the existence of ES (Chi …
Helicobacter Pylori Seropositivity In Children Withrecurrent Abdominal Pain, Engin Günel, Duygu Findik, Fatma Çağlayan, Zerrin Topgaç
Helicobacter Pylori Seropositivity In Children Withrecurrent Abdominal Pain, Engin Günel, Duygu Findik, Fatma Çağlayan, Zerrin Topgaç
Turkish Journal of Medical Sciences
Recurrent abdominal pain (RAP) is a significant problem in pediatric patients, and there has been much recent interest in the role that Helicobacter pylori (Hp) might play in this disorder. The aim of the study was to determine the prevalance of Hp infection in children with RAP, and to determine whether there was an association between Hp and RAP. The study was conducted on 50 children with RAP and 20 asymptomatic children admitted for inguinal surgery as a control group. Serum samples from the 70 children were tested for anti-Hp Ig G and anti-Hp Ig A by ELISA. Of the …
G6pd Deficiency In Turkish Cypriots, Ayşe Sözüöz, İlkay Çamber
G6pd Deficiency In Turkish Cypriots, Ayşe Sözüöz, İlkay Çamber
Turkish Journal of Medical Sciences
1108 Turkish Cypriot men and 318 male labourers from mainland Turkey were screened for G6PD deficiency and haemoglobinopathy traits. The results revealed a 6.7% G6PD deficiency rate in the Turkish Cypriot men and a 1.6% prevalance rate in the Turkish men. The mean haemoglobin level of the G6PD deficient males was approximately 1g/dl lower than that of the non-deficient males.
Rehabilitation Outcome In 305 Turkish Patientswith Cerebral Palsy, Neşe Özgi̇rgi̇n, Füsun Güler-Uysal
Rehabilitation Outcome In 305 Turkish Patientswith Cerebral Palsy, Neşe Özgi̇rgi̇n, Füsun Güler-Uysal
Turkish Journal of Medical Sciences
The aim of this stduy was to evaluate the eitology, clinical distribution, complications, progress and hospitalization time of the cerebral palsy patients treated at Ankara Rehabilitation Center during the last 2.5 years. Clinical grouping was done according to the John F. Kennedy Institute system of clasification. Degrees of head control, sitting balance, ability to crawl, balance on hands and knees, standing balance, gait and ambulation on admission and discharge were compared. The study group consisted of 305 patients (ages 2-14, mean 5.8; 129 girls and 176 boys). Perinatal factors were the most common etiologic factors in cerebral palsy. The clinical …
Detrusor Hyperreflexia In Stroke, Zafer Aybek, Türker Şahi̇ner, Atilla Oğuzhanoğlu, Levent Tuncay
Detrusor Hyperreflexia In Stroke, Zafer Aybek, Türker Şahi̇ner, Atilla Oğuzhanoğlu, Levent Tuncay
Turkish Journal of Medical Sciences
In this study detrusor hyperreflexia was investigated by urodynamic study during the acute phase of stroke in patients who became incontinent after a cerebrovascular accident. Urodynamic studies reveal physiopathological findings of incontinence while the acute period of cerebrovascular accident do not cover neurogenic bladder features. In our study it was observed that most of the patients (60%) had normal bladder functions and detrusor hyperreflexia was a rare rindings. This result is consistent with the other studies in literature.
The Effects Of Different Metal Surfacetreatments On Marginal Microleakage In Resin-Bondedrestorations, Y. Şinasi Saraç, Kürsat Eser, Bedri Beydemi̇r, Tanju Akbay
The Effects Of Different Metal Surfacetreatments On Marginal Microleakage In Resin-Bondedrestorations, Y. Şinasi Saraç, Kürsat Eser, Bedri Beydemi̇r, Tanju Akbay
Turkish Journal of Medical Sciences
Margins are one of the most important aspects in the success of restorations. Therefore, we evaluated the effects of different metal surface treatments on the marginal microleakage of a resinbonded non-precious alloy (Remanium CS). After alloy surfaces were roughened by chemical etching or sandblasting the tooth and metal specimens were bonded together in pairs with a chemically curing resin cement (Panavia 21 EX) and placed in methylene blue dye. Spectrophotometry was used to assess marginal leakage. Statistical analysis was completed using the ANOVA test. No statistically significant difference in leakage was found between the groups (F=0.4387, p>0.05).
Tubo Ovarian Abscess: Risk Factors And Clinicalfeatures In Turkish Population, Didem Akyol, Utku Özcan, Murat Eki̇n, Tayfun Güngör, Oya Gökmen
Tubo Ovarian Abscess: Risk Factors And Clinicalfeatures In Turkish Population, Didem Akyol, Utku Özcan, Murat Eki̇n, Tayfun Güngör, Oya Gökmen
Turkish Journal of Medical Sciences
No abstract provided.
Stage Ii Multiple Extramedullary Plasmacytoma,Synchronous The Nasal Polyps Of The Head &Neck. A Case Report And Review Of The Literature, Enver Altas, Cemal Gündoğdu, Harun Üçüncü, R. Murat Karasen, Hasan Kaya, Fazli Erdoğan
Stage Ii Multiple Extramedullary Plasmacytoma,Synchronous The Nasal Polyps Of The Head &Neck. A Case Report And Review Of The Literature, Enver Altas, Cemal Gündoğdu, Harun Üçüncü, R. Murat Karasen, Hasan Kaya, Fazli Erdoğan
Turkish Journal of Medical Sciences
No abstract provided.
Primary Malignant Hemangiopericytomapresenting As A Pancoast Tumor, A. Füsun Kalpaklioğlu, Beyhan Demi̇rhan, Mehmet Coşkun
Primary Malignant Hemangiopericytomapresenting As A Pancoast Tumor, A. Füsun Kalpaklioğlu, Beyhan Demi̇rhan, Mehmet Coşkun
Turkish Journal of Medical Sciences
No abstract provided.
Digital Amputations Caused By Amniotic Bandsa Case Report, Volkan Baltaci, Didem Akyol, Davut Gül, Bekir Sıtkı Sayli
Digital Amputations Caused By Amniotic Bandsa Case Report, Volkan Baltaci, Didem Akyol, Davut Gül, Bekir Sıtkı Sayli
Turkish Journal of Medical Sciences
No abstract provided.
A Case Of Atypical Cogan's Syndrome And Reviewof Literature, Murat Aksu, Ali Özdemir Ersoy, Sarper Karaküçük, Hakkı Doğan
A Case Of Atypical Cogan's Syndrome And Reviewof Literature, Murat Aksu, Ali Özdemir Ersoy, Sarper Karaküçük, Hakkı Doğan
Turkish Journal of Medical Sciences
No abstract provided.
Detection Of Antinuclear Antibody (Ana) Inpatients With Mycoplasmal Pneumonia, Sevtap Arikan, Sibel Ergüven, Şemsettin Ustaçelebi̇
Detection Of Antinuclear Antibody (Ana) Inpatients With Mycoplasmal Pneumonia, Sevtap Arikan, Sibel Ergüven, Şemsettin Ustaçelebi̇
Turkish Journal of Medical Sciences
No abstract provided.
Ischemia-Reperfusion Injury, Reactive Oxygenmetabolites, And The Surgeon, A.Özdemir Aktan, A. Süha Yalçin
Ischemia-Reperfusion Injury, Reactive Oxygenmetabolites, And The Surgeon, A.Özdemir Aktan, A. Süha Yalçin
Turkish Journal of Medical Sciences
No abstract provided.