Medical Education Commons^™

The Relationship Between Resistance Exercise Induced Testosterone And Cortisol Responses And Steroid Receptor Phosphorylation, Borna Golbarg, Justin X. Nicoll, Stephanie A. Sontag, Eric M. Mosier, Andrew C. Fry

International Journal of Exercise Science: Conference Proceedings

The precise contribution of hormones to resistance training adaptations remains unclear. Recently, resistance exercise (RE) has been shown to change phosphorylation of androgen (pAR) & glucocorticoid receptors (pGR). Examining the relationships between the hormonal responses & steroid receptor phosphorylation may elucidate the role of acute hormonal responses to training adaptations. PURPOSE: The purpose of this study was to examine relationships between exercise-induced hormonal responses and pGR & pAR. METHODS: Resistance trained (RT) (n = 10; age = 21.3±1.7yrs, ht = 175.8±6.8cm, bodymass = 84.5±13.5kg) & untrained (UT) (n = 9; age = 20.8±3.1yrs, ht = 178.7±8.9cm, bodymass = …

Modeling The Oxidative Metabolic Breakdown Of Ethanol And Its Effects On The Cardiovascular System, Jessica F. Farfan, Allan Knox, Grady Hanrahan

International Journal of Exercise Science: Conference Proceedings

Chronic ethanol consumption contributes to the global prevalence’s of cardiovascular disease by mechanisms involving an inflammatory response and consequent lipid peroxidation. Cytochrome p450 is a part of the microsomal ethanol oxidizing system (MEOS) and can utilize iron complexes and the reductant NADPH to catalyze the breakdown of acute/chronic ethanol consumption. However, efficacy of MEOS to prevent cardiovascular burden induced by ethanol consumption is not clear. PURPOSE: To demonstrate the response of the cardiovascular system in response to the oxidative metabolic breakdown of ethanol via MEOS. METHODS: An extensive literature search provided data to develop a mechanistic model of the metabolism …

Features Of A Mediterranean Diet And Mental Health Outcomes In College Students, Jessica Wisse, Gabriella Marchal, Claire Duisenberg, Hawley Almstedt

International Journal of Exercise Science: Conference Proceedings

Up to 30% of college students are reported to suffer from depression or anxiety. Previous studies have produced correlations between nutritional variables and mental health outcomes in adults. Specifically, variables featured in the Mediterranean diet, including increased fiber, monounsaturated fat, omega-3 fatty acids, fruit and vegetable intake, and decreased added sugars have been associated with more favorable mental health outcomes. PURPOSE: This research was conducted to explore relationships between specific variables included in the Mediterranean diet and mental health symptoms in college students. METHODS: To collect data on diets, participants were given three-day diet records to record food and beverage …

The Effects Of Resistance Training And Protein Supplementation On Bone Mineral Density In Untrained Women, Jessica Smith

International Journal of Exercise Science: Conference Proceedings

Peak bone mass has been found to plateau at approximately 30 years of age; therefore, is it important to develop a higher peak bone mass early in life. Resistance exercise has been shown to improve bone mineral density (BMD) based on a great enough strain and mechanical load to promote bone formation. Resistance exercise is known to stimulate muscle protein synthesis, which can thereby raise individual protein needs above the recommended daily allowance (RDA). Resistance training (RT) combined with a protein intake above the RDA (> 0.8 g/kg/day) may be superior in promoting greater changes in BMD compared to RT …

Effects Of Co-Ingesting Dietary Nitrate And Vitamin C On Nitric Oxide Bioavailability, Blood Pressure, And Cardiovascular Reactivity In Hispanic Females, Joanna Powell, Katherine M. Price, Isabella G. Lincoln, Keonabelle P. Paniagua, Sean T. Karl, Julie Ahn, Noelle G. Seekamp-Hicks, Lauren Wideen, Joshua Park, Rachel Tan

International Journal of Exercise Science: Conference Proceedings

High blood pressure is a hallmark of chronic disease and is disproportionately prevalent in ethnic minorities. Dietary nitrate has been shown to lower blood pressure via increased nitric oxide (NO), but few studies have examined if combining nitrate with vitamin C (VITC) could have beneficial synergistic effects on blood pressure by augmenting NO, and limited data exist in females. PURPOSE: To investigate if combining nitrate-rich beetroot juice (BR) with VITC could further augment NO bioavailability and improve blood pressure in Hispanic females compared to BR and VITC ingested alone. METHODS: Eight sedentary Hispanic females participated in four conditions …

Time Course Evaluation Of Mapk Phosphorylation To Resistance Exercise: A Systematic Review, Justin X. Nicoll, Christopher J. Lee

International Journal of Exercise Science: Conference Proceedings

Mitogen activated protein kinases (MAPK) are intramuscular cell signaling proteins that regulate adaptations to resistance exercise (RE). The MAPKs extracellular signal-regulated kinase 1/2 (ERK1/2), c-jun N-terminal kinase (JNK), p90RSK, and p38-MAPK increase during and after RE. Despite the well-known increase in post-RE phosphorylation responses of MAPK, the time-course and pattern of their activation remains unclear and poorly described. The ability to clearly define phosphorylation patterns during recovery are limited due to the variety of RE protocols implemented and populations tested when investigating MPAK responses to RE. PURPOSE: To systematically review literature on exercise-induced phosphorylation of ERK1/2, JNK, p38-MAPK, and …

The Effects Of Acute Beetroot Juice Ingestion On Exercise And Cognitive Performance In Female Athletes, Isabella G. Lincoln, Courtney Merrill, Katherine M. Price, Sean T. Karl, Ryan T. Kenney, Alyssa A. Riley, Chandler F. Riley, Maya A. Hammer, Adam Pennell, Rachel Tan

International Journal of Exercise Science: Conference Proceedings

Nitrate-rich beetroot juice can enhance intense exercise performance which is attributed to enhanced skeletal muscle contractility. However, limited data exist in females and it is unknown whether dietary nitrate has an ergogenic effect in this population. PURPOSE: To investigate the potential effects of acute nitrate ingestion on a battery of exercise performance and cognitive tests before and after fatiguing intermittent running exercise. METHODS: Fifteen female team-sport athletes were assigned in a randomized, double-blind, crossover design to consume nitrate-rich beetroot juice (BR; 12 mmol of nitrate) and nitrate-depleted beetroot juice (PL; 0.10 mmol of nitrate) 2.5 h prior to …

Exercise And Esr1 Control Mitochondrial Content And Function To Regulate Adiposity, Alice M. Ma, Nicole Lee Yang, Alexander R. Strumwasser, Zhenqi Zhou, Andrea L. Hevener

International Journal of Exercise Science: Conference Proceedings

Mechanisms that underlie adipose tissue remodeling to enhance metabolic health in response to exercise training remain inadequately understood. PURPOSE: We utilized mouse genetics and human GWAS to determine the impact of exercise training on mitochondrial DNA copy number, and interrogate the relationship between Esr1 and adipose tissue health. METHODS: We performed RNAseq on adipose tissue from 100 strains of inbred mice following exercise training and determined mitochondrial content by qPCR. We performed deep phenotyping of mice harboring conditional Esr1 overexpression selectively in adipose tissue. Adipose specific Esr1 overexpression and control mice were fed a high fat diet and …

Novel Energy Drink Improves Mood And Raises Blood Pressure, But Has No Effect On Cardiac Qtc Interval Or Rate-Pressure Product In Young Adult Gamers, Nathaniel Helwig, Laura Schwager, Emily Rogers, Nile Banks, Chris Lockwood, Nathaniel D.M. Jenkins

International Journal of Exercise Science: Conference Proceedings

Novel energy drink formulations have been introduced to the market that are purported to have nootropic effects – including improving mood. Despite their rapidly growing popularity, especially among video gamers, there is minimal evidence supporting their efficacy or establishing their cardiovascular safety profiles. PURPOSE: We conducted a randomized, double-blind, placebo-controlled, crossover trial to investigate the effects of acute consumption of a non-caloric, novel energy drink (NED) containing 200 mg caffeine, citicoline, tyrosine, B-vitamins, and carboxylic acids on mood and cardiovascular safety outcomes. We hypothesized that NED would improve mood without significant adverse cardiovascular effects when compared to placebo. METHODS: Forty-five …

Effects Of 8-Week Ketogenic Diet On Anthropometrics, Body Composition, Metabolic Parameters, And Psychological Factors In Young Obese Population, Hayden G. West, Soon-Mi Choi, Frank B. Wyatt, Michael W. Olson

International Journal of Exercise Science: Conference Proceedings

Obese have a significantly higher Body Mass Index (BMI), which can be associated with poor nutritional intake and sedentary lifestyles. The ketogenic diet is a form of a dietary intervention which is often implemented for metabolic syndrome individuals such as obese populations. PURPOSE: The purpose of this study was to measure the effects of a ketogenic diet on anthropometrics, body composition, metabolic parameters, and psychological factors in young obese population. METHODS: Seven young obese participants (n=7, height (cm); 174.8 ± 10.9, weight (kg); 105 ± 20.7, BMI (kg∙m^-2); 34.6 ± 4.8) completed an 8-week intervention with …

Impact Of Menstrual Phases On Stress Markers: A Pilot Study, Bailey C. Weishaar, Hunter S. Waldman, Kyle T. Patek, Matthew J. Mcallister

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Previous research has shown that different phases of the menstrual cycle may impact biometrics such as markers of stress and inflammation [e.g., cortisol (CORT), interleukin-6] as well as body composition. However, there is scarce literature regarding markers of stress and oxidative stress such as salivary a-amylase (sAA), immunoglobin-A (SIgA) and uric acid (UA), in relation to the four different menstrual phases. The purpose of this study was to examine the impact of menstrual phases on sAA, CORT, UA and SIgA. METHODS: 21 pre-menopausal women with regular menstrual cycles (n=9) oral contraceptive users (OC) and ( …

Measurement Of Respiratory Exchange Ratio (Rer) With Oral Versus Oronasal Breathing After Sports Drink Mouth Rinse, Meeshti Shethia, Edward Merritt

International Journal of Exercise Science: Conference Proceedings

The ratio of carbon dioxide produced to oxygen consumed, the respiratory exchange ratio (RER), is often used to determine the balance of carbohydrate and fat oxidation during exercise. However, introducing carbohydrates into the mouth and pharynx could possibly influence the value while not actually changing the whole-body metabolism. PURPOSE: The purpose of this study was to determine if a sports drink mouth rinse during steady-state (SS) exercise affects RER. METHODS: Eleven participants exercised at steady state in 4 different, randomized conditions while respiratory gases were analyzed: 1) Breathing through the mouth after water rinse; 2), breathing through the mouth …

The Effects Of Body Composition On Resting Metabolic Rate Among College Aged Students, Natalie A. Delgadillo, Frank Wyatt, Michael W. Olson, Soon-Mi Choi

International Journal of Exercise Science: Conference Proceedings

Resting metabolic rate (RMR) is the measure of daily energy expenditure while the body is at rest. RMR is becoming more useful in order to measure the energy demands in both athletes and non-athletes. PURPOSE: The purpose of this study is to analyze the RMR among college aged students, along with their body compositions in order to determine if there is a correlation between body fat percentage and RMR. METHODS: Participants in this study included 19 students at Midwestern State University between the ages of 19-25. (n = 19; female = 12; male = 7). Participants were asked prior …

Metabolic Flexibility In Healthy Hispanics In The Rio Grande Valley With And Without A Family History Of Type 2 Diabetes, Jaime Rodriguez, Ryan D. Russell, Gabriel A. Figueroa, Alexandro Rodriguez, Smaran Marupudi, Yu Lun Tai, Sara Swathy, Jimmy Gonzales

International Journal of Exercise Science: Conference Proceedings

ABSTRACT Type 2 Diabetes (T2D) has several comorbidities such as cardiovascular disease, elevated lipid profile, microvascular complications, and impaired metabolic flexibility (MF: the ability to switch substrate use upon stimulation). Further, healthy Caucasians with a family history of T2D (FH+) have impaired MF similar to T2D, suggesting impaired MF could be an early-detection tool to identify at-risk populations. Hispanics of the Rio Grande Valley have ~3x the T2D rates as the US average, and have ~79% of the people in this region are either overweight or obese. However, patterns of MF in this population have not been addressed. Purpose: The …

Athlete Perceptions Of Flavored, Menthol-Enhanced Energy Gels Ingested Prior To Running In The Heat, Roxanne M. Vogel, Christopher J. Stevens, Christian Swann, Megan L. Ross

International Journal of Exercise Science: Conference Proceedings

Thermal perception during exercise is known to influence endurance performance and the onset of fatigue. L-menthol, an organic compound derived from peppermint, evokes a cooling sensation through its action on TRPM8 channels which also respond to cold stimuli. Recent work identified that the internal application of menthol-enhanced fluids can be ergogenic during exercise in the heat. Hence, the addition of menthol to energy gels may be practical and beneficial for athletes. PURPOSE: To determine athlete acceptability and preferences for flavored energy gels with different menthol concentrations. METHODS: With a randomized, crossover, and double-blind placebo-controlled design, 27 endurance athletes …

Reverting To A Healthier Diet Or Employing An Aerobic Exercise Regime Independently Restore Muscle Fiber Phenotype Disturbed By High-Fat Diet In Muscle Of Mice, Nathan Serrano, Harkaran S. Sodhi, Kailin Johnsson, Laurel B. Winslow, Layla Al-Nakkash, Christos S. Katsanos

International Journal of Exercise Science: Conference Proceedings

Obesity affects roughly 42% of the US population. High fat/high sugar diets (HFHS) often referred to as “western diet” contributes to this prevalence. Diet-induced obesity results in impaired metabolic responses and associated disease states (i.e., Type 2 Diabetes). Metabolic impairments in diet-induced obesity are a result of changes in muscle metabolism, and changes in muscle fiber phenotype, which is determined by the isoform-content of the protein myosin heavy chain (MHC). Fast muscle fiber phenotype (i.e. type IIb in mice) is characterized by lower capacity for utilization of lipids, implicated in the pathogenesis of Type 2 Diabetes. Regular exercise shifts MHC …

Effect Of 4-Week Creatine Monohydrate Supplementation On Absolute Strength In Trained And Untrained Healthy Adults, Carson C. Vollmer, Brittany K. Sanchez

International Journal of Exercise Science: Conference Proceedings

Creatine monohydrate (CrM) is a synthetic form of creatine which has similar effects on the body as compared to the endogenous form. Creatine is used by the body to supply rapid ATP to muscles for contractile movements and is regularly obtained in the diet, primarily from meat products, or synthesized by the liver at a 24-hour turnover rate of approximately 1-2 g/day. Creatine supplementation is commonly used with the intention of improving muscular strength and hypertrophy for athletic performance along with enhanced recovery time, injury prevention, rehabilitation, and potential neuroprotective benefits. PURPOSE: The specific aim of this study is …

Cannabis And Cannabidiol Use In Active Individuals: A Survey Of Timing And Reasons For Use, Matthew M. Schubert, Jamie E. Hibbert, Richard Armenta, Erik A. Willis, Whitney Ogle

International Journal of Exercise Science: Conference Proceedings

The use of cannabis for medicinal and recreational purposes is widespread across the globe. However, relatively little is known regarding the use of cannabis and its constituents among athletic populations. PURPOSE: The aim of this study was to examine timing of cannabis use relative to exercise, reasons for use, forms of consumption, and sources of information in active adults. METHODS: This cross-sectional survey was administered electronically beginning in September 2020. Participants were recruited through social media advertisements, email blasts, and word of mouth. Data were collected on health and exercise habits, use of cannabis/cannabidiol (CBD), reasons for use, …

The Role Of Physical Activity In The Relationship Between Sitting Time And Insulin Resistance, Kayla Parker, Larry A. Tucker

International Journal of Exercise Science: Conference Proceedings

PURPOSE: The primary objective of the present study was to determine the role of physical activity in the relationship between sitting time and insulin resistance in 7,092 randomly selected U.S. adults. METHODS: Cross-sectional data from the National Health and Nutrition Examination Survey (NHANES), 2011-2018, were used to answer the research question. NHANES data for 2019-2020 were not available because of COVID. Participants were selected using a multi-stage, random sampling strategy. Subjects reported average sitting time, quantified as the number of minutes spent per day sitting. Insulin resistance was determined using HOMA-IR (homeostatic model assessment). HOMA-IR is the most common measure …

Estrogen Receptor Alpha Controls Mitochondrial Function And Metabolic Homeostasis, And Is Critical For Exercise-Induced Improvements In Metabolism, Alexia M. Joseph

International Journal of Exercise Science: Conference Proceedings

Skeletal muscle is an important tissue responsible for locomotion, oxidative metabolism, and insulin-stimulated glucose disposal. Because exercise is the most effective means to combat metabolic dysfunction and prevent the progression of type 2 diabetes, our laboratory is interested in understanding the molecular transducers underlying the health benefits of exercise. Previous work by our group has shown that muscle ESR1/ERα expression is correlated with indices of metabolic health, and Esr1 expression in muscle is induced following exercise training.

PURPOSE: Determine whether genetic overexpression of Esr1 to mimic transcript induction by physical activity is sufficient to produce favorable metabolic changes …

The Effects Of Multiple Bouts Of Tabata On Post-Exercise Metabolism: A Pilot Analysis, Blake W. Johnson, Alexander Alvara, James R. Rowe Jr

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Compare the resting metabolic rate (RMR) following: 1) no exercise (REST), 2) completion of 1 bout of TABATA (1-BOUT), 3) completion of 2 bouts of TABATA (2-BOUT), and 4) completion of 10 bouts of TABATA (10-BOUT). METHODS: Recreationally active individuals (n = 5; 1F, 4M; age = 23.4 ± 1.9 yrs; body mass = 72. 7.2 ± 16.9 kg; body fat% = 28.7 ± 4.9) performed each of the 4 protocols on separate days with at least 7 days in between protocols. Rest consisted of not exercising on the day of the assessment. 1-BOUT consisted of performing a …

Influence Of Diet On Metabolic Physiology In People With And Without A Family History Of Type 2 Diabetes, Smaran Marupudi, Yu Lun Tai, Gabriel Figueroa, Saraswathy Nair, Jimmy Gonzalez, Emily Cisneros, Ryan D. Russell

International Journal of Exercise Science: Conference Proceedings

Type 2 diabetes (T2D) prevalence in the Rio Grande Valley is ~27% versus the 9% national average. Simply having a family history (FH+) of type 2 diabetes (T2D) increases T2D prevalence by ~40 over those with no family history (FH-). We have shown that FH+ display early markers of cardiometabolic impairment vs FH-, such as blunted microvascular reactivity, and impaired metabolic flexibility. What is not yet known is the degree to which environment vs genetics may contribute to these impairments. PURPOSE: This pilot study seeks to examine normal dietary patterns between FH groups to identify potential patterns in macro- and …

The Relationship Between Dietary Intake And Sleep Quality In Endurance Athletes, Kamiah Moss, Andreas Kreutzer, Austin J. Graybeal, Yan Zhang, Robyn Braun-Trocchio, Ryan R. Porter, Meena Shah

International Journal of Exercise Science: Conference Proceedings

Athletes have a high prevalence of poor sleep quality. It is unknown if dietary intake affects sleep quality in athletes. PURPOSE: To examine if sleep quality in endurance athletes is related to dietary intake. METHODS: Endurance athletes (n=187), 42.0±13.7 y, participated in the study. Participants completed questionnaires on demographics, dietary intake, and sleep quality. Sleep quality was assessed using the Athlete Sleep Screening Questionnaire (ASSQ), a validated tool, with scores ranging from 0-40 (higher scores indicate poorer sleep quality). The ASSQ subscales included sleep difficulty (SD), chronotype (C), and sleep disordered breathing (SDB). ASSQ-SD was categorized as having …

The Effect Of Acute And Chronic Thermotherapy On Type 2 Diabetic Skeletal Muscle Cell Viability And Gene Expression: Pilot Study, Louay Bachnak, Jean Sparks, Xavier F. Gonzales, Daniel Newmire, Felix Omoruyi

International Journal of Exercise Science: Conference Proceedings

Diabetes is a chronic metabolic disease affecting millions of people globally. Type 2 diabetes is associated with insulin resistance or a defective secretion of insulin from the pancreas. The skeletal muscle system accounts for 80% of glucose uptake and is a vital player in healthy aging and muscle mass maintenance. PURPOSE: The purpose of this study was to investigate the effects of thermotherapy on gene expression and cell viability in Type 2 Diabetic skeletal muscle. METHODS: Human skeletal muscle myoblast (HSMM) and Diabetic Type 2 human skeletal muscle myoblast (D-HSMM) (Lonza Inc, Walkersville, MD) were cultured until 90% confluency was, …

Disuse Atrophy Occurs Without A Change In Mitochondrial Respiratory Control Ratio During Hindlimb Unloading In Mice, Indu Reddy Enukonda, Megan E. Rosa-Caldwell, David E. Lee, Jacob L. Brown, Richard A. Perry, Tyrone A. Washington, Nicholas P. Greene, Michael P. Wiggs

International Journal of Exercise Science: Conference Proceedings

Skeletal muscle atrophy commonly occurs during prolonged periods of inactivity, however, the precise mechanisms that cause muscle atrophy have yet to be determined. Specifically, a controversy exists on whether mitochondrial dysfunction is a cause or consequence of disuse muscle atrophy. PURPOSE: The purpose of this study was to determine if a change in the respiratory control ratio, which is a ratio of maximal O₂ respiration to leak respiration, could be detected prior to muscle atrophy in a time-course study in mice. METHODS: Disuse atrophy was induced using hindlimb unloading (HU) in adult, C57BL/6J male mice for 0 …

Replicating Intermittent Fasting In Human Skeletal Muscle Cells: A Pilot Study, Lael K. Ceriani, Felix Omoruyi, Jean Sparks, Daniel E. Newmire, Xavier F. Gonzales

International Journal of Exercise Science: Conference Proceedings

Type 2 diabetes (T2D), the most common form of diabetes (90-95% of diagnoses), is marked by decreased insulin sensitivity (insulin resistance) or a defect in insulin secretion. T2D disrupts nutrient signaling where the body cannot maintain adequate blood glucose levels. Inability to receive glucose in skeletal muscle due to insulin resistance in T2D results in oxidative stress and increased muscle atrophy. Properly regulated glucose uptake is pivotal for healthy aging and maintenance of the skeletal muscle system. PURPOSE: The purpose of this study is to examine the effects of nutrient deprivation on human skeletal muscle metabolism, with an emphasis …

A Comparison Of High-Intensity Interval Running And Tabata On Post-Exercise Metabolism, Lauren E. Pate

International Journal of Exercise Science: Conference Proceedings

It is unclear how post-exercise metabolism would compare following the completion of 2 different modes of high-intensity exercise. PURPOSE: Compare the effects of high-intensity interval running (HIIR) and Tabata when performed at a similar duration and intensity. METHODS: Recreationally active individuals (n = 7; 6F, 1M; age = 22.2 ± 2.1 yrs; body mass = 64.2 ± 12.0 kg; body fat% = 26.2±3.1) completed 1) a rest bout, 2) a Tabata bout using only body callisthenic exercises, and 3) a bout of high-intensity interval running (HIIR) on a motorized treadmill. Participants performed each of the 3 bouts on separate …

Acute Maltodextrin Supplementation During Resistance Exercise, Dylan T. Wilburn, Steven Machek, Tom Cardaci, Paul Hwang, Darryn Willoughby

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Most of the research investigating the ergogenic enhancing mechanisms of carbohydrate have been conducted using aerobic based exercise. Therefore, the purpose of this study was to investigate the effects of pre-exercise maltodextrin ingestion on resistance exercise performance, serum insulin, epinephrine, glucose, and muscle glycogen concentrations. METHODS: In a double blind, cross over, repeated measures design, participants completed four sets to failure at 70% of 1-RM with 45s rest on the angled leg press with or without pre-exercise maltodextrin (2g/kg) after a 3hr fast. Serum glucose, epinephrine, and insulin were assessed at baseline, 30 min post-ingestion, immediately after, and 1hr …

Ubiquitin Proteasome System Activity Is Suppressed By Curcumin Following Exercise-Induced Muscle Damage In Human Skeletal Muscle, Thomas D. Cardaci, Steven B. Machek, Dylan T. Wilburn, Paul S. Hwang, Darryn Willoughby Phd

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Curcumin is a natural polyphenolic compound with antioxidant and anti-inflammatory properties. In vitro and in vivo animal studies have demonstrated that exposure to curcumin leads to dysregulation of the ubiquitin-proteasome system (UPS). However, to date, no study has investigated curcumin’s ability to influence UPS activity in a human model. Therefore, the purpose of this study was to investigate the effects of curcumin supplementation on markers of UPS activity in the presence of elevations in UPS activity due to exercise-induced muscle damage. METHODS: Twenty-three recreationally active male and female participants between the ages of 18-30 were randomized into …

Plasma Lipid, Glucose, And Immune Responses To Consumption Of Nutritive And Nonnutritive Sweeteners And Exercise, Jarrett Walbolt, Yunsuk Koh

International Journal of Exercise Science: Conference Proceedings

Although nonnutritive sweeteners are widely used as substitutes for nutritive sweeteners, it is currently uncertain how these commonly available sweeteners affect plasma glucose and lipid metabolism. PURPOSE: To examine how nutritive and nonnutritive sweeteners influence plasma lipid profiles, complete blood counts, and plasma glucose content at rest and during exercise. METHODS: This randomized, double-blinded, cross-over design study included 9 healthy, college aged, individuals (4 females and 5 males). In four separate visits, participants consumed 8 oz of sweetened drink in random order with either 445mg of stevia, 507mg of aspartame, 169mg of sucralose, or 110,000mg of sucrose mixed into water. …