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Articles 1 - 19 of 19
Full-Text Articles in Virus Diseases
Metabolic And Replicative Constraints On Pathogen Virulence: Isoleucine Catabolism In Shigella And Comparative Tanapoxvirus Replication In Cell Cultures, Benecia Angelica
Metabolic And Replicative Constraints On Pathogen Virulence: Isoleucine Catabolism In Shigella And Comparative Tanapoxvirus Replication In Cell Cultures, Benecia Angelica
Masters Theses
Pathogens survive by balancing metabolic demands with environmental challenges that shape their virulence and adaptability. Shigella flexneri, a highly infectious human pathogen responsible for severe diarrheal disease worldwide, utilizes branched-chain amino acid (BCAA) metabolism to withstand stress conditions encountered within the host environment. In this study, we explored the Shigella isoleucine catabolism pathway by knocking out four genes in the S. flexneri isoleucine catabolic pathway (ilvE, fadA, fadD, and acnB) and examining their metabolism and virulence. We found that the ilvE and acnB mutants displayed reduced metabolic activity and smaller plaque size, while the fadD mutant showed decreased invasion. In …
Ritual During Covid-19, Stephen Covell, Diane Riggs, Cameron Borg, Ryan Lemasters, Jacob Riccioni
Ritual During Covid-19, Stephen Covell, Diane Riggs, Cameron Borg, Ryan Lemasters, Jacob Riccioni
Modules for Teaching Pandemic Response and Religion in the USA
The following teaching module is designed for high school and college level instructors who seek to teach a lesson on the impact the COVID-19 pandemic had on the participation and practice of religious rituals. The teaching module features a lesson plan, case studies, and assignments that can be incorporated as the instructor sees fit. This teaching module was created by Western Michigan University's Department of Comparative Religion.
Gender, Monastic Life, And The Lay Community During The Pandemic, Stephen Covell, Diane Riggs, Cameron Borg
Gender, Monastic Life, And The Lay Community During The Pandemic, Stephen Covell, Diane Riggs, Cameron Borg
Modules for Teaching Pandemic Response and Religion in the USA
The following teaching module is designed for high school and college level instructors who seek to teach a lesson on the impact the COVID-19 pandemic had on the monastic life of both Buddhists and Catholics. The teaching module features a lesson plan, case studies, and assignments that can be incorporated as the instructor sees fit. This teaching module was created by Wester Michigan University's Department of Comparative Religion.
Coronavirus (Covid-19) And Religious Holidays In The U.S., Stephen Covell, Diane Riggs, Cameron Borg, Jarrett Stalinger, Jacob Riccioni
Coronavirus (Covid-19) And Religious Holidays In The U.S., Stephen Covell, Diane Riggs, Cameron Borg, Jarrett Stalinger, Jacob Riccioni
Modules for Teaching Pandemic Response and Religion in the USA
The following teaching module is designed for high school and college level instructors who seek to teach a lesson on the impact the COVID-19 pandemic had on the celebration of religious holidays, such as Ramadan, Passover, and Easter. The teaching module features a lesson plan, case studies, and assignments that can be incorporated as the instructor sees fit. This teaching module was created by Western Michigan University's Department of Comparative Religion.
Orthodox Jewish Women And Ritual Purity During The Pandemic, Stephen Covell, Diane Riggs, Cameron Borg
Orthodox Jewish Women And Ritual Purity During The Pandemic, Stephen Covell, Diane Riggs, Cameron Borg
Modules for Teaching Pandemic Response and Religion in the USA
The following teaching module is designed for high school and college level instructors who seek to teach a lesson on the impact the COVID-19 pandemic has had on Jewish women and their ritual purity. The teaching module features a lesson plan, case studies, and assignments that can be incorporated as the instructor sees fit. This teaching module was created by Western Michigan University's Department of Comparative Religion.
Public Policy And Religion In The Pandemic: U.S. Constitution And The First Amendment, Stephen Covell, Diane Riggs, Cameron Borg
Public Policy And Religion In The Pandemic: U.S. Constitution And The First Amendment, Stephen Covell, Diane Riggs, Cameron Borg
Modules for Teaching Pandemic Response and Religion in the USA
The following teaching module is designed for high school and college level instructors who seek to teach a lesson on the impact the COVID-19 pandemic had on the relationship between church and state. The teaching module features a lesson plan, case studies, and assignments that can be incorporated as the instructor sees fit. This teaching module was created by Western Michigan University's Department of Comparative Religion.
Considerations For Events And Gatherings, Centers For Disease Control And Prevention
Considerations For Events And Gatherings, Centers For Disease Control And Prevention
Pandemic Response and Religion in the USA: Law and Public Policy
No abstract provided.
Checklist For Communities Of Faith, Centers For Disease Control And Prevention
Checklist For Communities Of Faith, Centers For Disease Control And Prevention
Pandemic Response and Religion in the USA: Health
This PDF from the Centers for Disease Control and Prevention provides a checklist for places of worship to use in order to prevent the spread of COVID-19 among their congregations. The checklist includes hygiene practices, disinfecting practices, social distancing, the use of masks, isolation, and support for those facing discrimination.
Faqs For Administrators And Leaders At Community- And Faith-Based Organizations, Centers For Disease Control And Prevention
Faqs For Administrators And Leaders At Community- And Faith-Based Organizations, Centers For Disease Control And Prevention
Pandemic Response and Religion in the USA: Health
This is the Frequently Asked Questions webpage from the Centers for Disease Control and Prevention designed to help places of worship prevent the spread of COVID-19 in their congregations. The FAQ page includes prevention strategies, community outreach strategies, and how to decide if services should be in person or virtual. Issues such as discrimination and marginalized populations are discussed on the FAQ page.
Community And Faith-Based Organizations: Plan, Prepare, And Respond, Centers For Disease Control And Prevention
Community And Faith-Based Organizations: Plan, Prepare, And Respond, Centers For Disease Control And Prevention
Pandemic Response and Religion in the USA: Law and Public Policy
No abstract provided.
Interim Guidance For Communities Of Faith, Centers For Disease Control And Prevention
Interim Guidance For Communities Of Faith, Centers For Disease Control And Prevention
Pandemic Response and Religion in the USA: Health
This article from the CDC offers guidelines for religious groups and organizations that are beginning to reopen and hold in-person services as stay-at-home orders are lifted. Guidelines include hygiene tips, disinfecting practices, the use of face masks, and other safe practices designed to keep houses of worship safe as they reopen. Other guidelines include policies for houses of worship to put in place for their congregants upon reopening, such as the use of worship materials.
The Bill Of Rights: What Does It Say?, The U.S. National Archives And Records Administration
The Bill Of Rights: What Does It Say?, The U.S. National Archives And Records Administration
Pandemic Response and Religion in the USA: Law and Public Policy
No abstract provided.
Convalescent Serum Therapy As Rapid Advance Treatment For Ebola In West Africa, J Bankole Thompson Md, Phd, Patricia F. Mejabi Msc., Olugbenga O. Mejabi Phd, S Ahmed Tejan-Sie Md
Convalescent Serum Therapy As Rapid Advance Treatment For Ebola In West Africa, J Bankole Thompson Md, Phd, Patricia F. Mejabi Msc., Olugbenga O. Mejabi Phd, S Ahmed Tejan-Sie Md
International Journal of African Development
The 2014 public health crisis in Guinea, Liberia, and Sierra Leone has brought Ebola Viral Disease (EVD) to everyone’s attention. Discovered in 1976, this deadly disease infrequently struck in remote areas of Africa. This article will critically review the literature and describe the pathobiology, transmission, signs and symptoms, diagnosis, treatment, and prevention of EVDwhich, was predicted by the Centers for Disease Control to potentially infect 1.4 million persons in Liberia and Sierra Leone by January 2015 (“Questions and Answers”, 2014). Thankfully this worst case scenario did not occur and we may be experiencing natural burn out of the outbreak along …
Oncolytic Tanapoxvirus Expressing Flic Causes Regression Of Human Colorectal Cancer Xenografts In Nude Mice, Steven J. Conrad
Oncolytic Tanapoxvirus Expressing Flic Causes Regression Of Human Colorectal Cancer Xenografts In Nude Mice, Steven J. Conrad
Dissertations
Cancers of the colon and rectum are a significant cause of morbidity and mortality worldwide and existing therapies often perform poorly for individuals afflicted with advanced stage disease. Oncolytic virotherapy is an emerging therapeutic modality which shows great promise for addressing this serious medical need. Herein we describe the in vivo testing of recombinant variants of the tanapoxvirus (TPV), a virus endemic to equatorial Africa which causes a mild and self-limiting disease in humans. Recombinant tanapoxviruses were made deleted for the 66R gene, the 2L gene, or both. Some of the recombinants were armed with mouse chemotactic protein 1 (m …
Vaccinia Virus Flll Mediated Expedition Of Tanapoxvirus Replication In Cell Culture, Yih Wen Goh
Vaccinia Virus Flll Mediated Expedition Of Tanapoxvirus Replication In Cell Culture, Yih Wen Goh
Masters Theses
Tanapoxvirus (TPV) produces large but slow-forming plaques as opposed to vaccinia virus (VACV) that forms similar large plaques but more rapidly. A number of genes were identified in VACV, inclucding FllL, A33R, A34R and A36R that contribute to the regulation of virus release and dissemination, and are particularly responsible for the induction of actin tails. Among them, TPV lacks homologs of the FllL and A36R genes. F11Lmediated inhibition of RhoA-mDia signaling was shown to enhance the microtubules dynamics and modulates the cortical actin that assisted in the release of progeny virus from infected cells. To understand the possible effects of …
The Partial Characterization Of The 142r Protein Of Tanapox Virus, Krystal N. Seibert
The Partial Characterization Of The 142r Protein Of Tanapox Virus, Krystal N. Seibert
Dissertations
Due to the complex nature of cancer, a variety of strategies are being employed to treat patients. Among these are oncolytic viruses that conditionally replicate in tumor cells with specific cellular landscapes. Several viruses including Herpesviruses, Adenoviruses, and Poxviruses, predominantly vaccinia virus (VV), have been explored for their oncolytic potential. Most of these viruses can productively infect a variety of cell types and it is one goal to create conditionally lethal viruses that can only replicate in tumor cells. Due to the prevalence of p53 inactivating mutations in cancers viruses that are restricted to p53 null cells are desirable and …
Discovery And Characterization Of A Tanapoxvirus Encoded Human Neuregulin Mimetic, David Jeng
Discovery And Characterization Of A Tanapoxvirus Encoded Human Neuregulin Mimetic, David Jeng
Dissertations
Studies on large dsDNA viruses such as poxviruses have been helpful in identifying a number of viral and cellular growth factors that contribute to our broad understanding of virus-host interaction. Orthopoxviruses and leporipoxviruses are among the most studied viruses in this aspect. However, tanapoxvirus (TPV) a member of the genus Yatapoxvirus, still remains largely unexplored, as the only known hosts for this virus are humans and monkeys. Here, we describe the initial characterization of an EGF-like growth factor mimicking human neuregulin from TPV, expressed by the TPV-15L gene. Assays using a baculovirus expressed and tagged TPV-15L protein demonstrated the ability …
Experimentation To Develop Procedures To Be Used In The Investigation Of The Effects Of Restriction On The Unmodified Dna Of The Bacteriophage Lamda, John Haynes
Honors Theses
The results of experimentation approximately twenty years ago with variuos bacteriophages by Ralston and Krueger16, Anderson and Felix1, Luria and Human12, and by Bertani and Weigle2 have shown that the host range of a given phage depends directly on the bacterial strain on which the phage has last propagated. This event came to be known as host-induced modification or host-controlled variation. As this phage host range is controlled by the host environment and can be altered from one generation to another it has, according to Luria, made microbiology "the last stronghold of Lamarckism" …
The Bill Of Rights: A Transcription, First Congress Of The United States
The Bill Of Rights: A Transcription, First Congress Of The United States
Pandemic Response and Religion in the USA: Law and Public Policy
No abstract provided.