Stomatognathic Diseases Commons^™

Differentiating The Mechanistic Role And Chemotherapeutic Potential Of Src And Podoplanin In Oncogenic Transformation, Edward P. Retzbach

Graduate School of Biomedical Sciences Theses and Dissertations

There were an estimated 20 million new cancer cases worldwide in 2020, resulting in nearly 1000 deaths per hour [1]. Oral cancer exemplifies the difficulties of treating cancer patients. The first line for oral cancer treatment is surgery and radiation that can lead to patient disfigurement and decreased quality of life in cancer survivors [2-4]. Though there have been many developments in chemotherapy in the last 30 years, the 50% mortality rate associated with oral cancer has not changed [4, 5]. Longitudinal studies that track survival rates in oral cancer patients demonstrate a 3-fold reduction in patient deaths when patients …

Is Laser Therapy Effective At Relieving Pain In Adult Patients With Recurrent Aphthous Stomatitis?, Kevin Jackson

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not laser therapy is effective at relieving pain in adult patients with recurrent aphthous stomatitis.

STUDY DESIGN: Systematic review of three randomized controlled trials published in 2009, 2009, and 2013.

DATA SOURCES: Three randomized controlled trials were obtained using PubMed.

OUTCOMES MEASURED: The symptom of pain was measured for improvement by patient survey of visual analog pain scales.

RESULTS: Prasad et al. (2013), Tezel et al. (2009), and Zand et al. (2009) all demonstrated improvement in a majority of the subjects’ pain relief from treatment with laser …

Is A Vitamin Supplement Effective In Treatment Of Recurrent Aphthous Ulcers?, Annalyse Grayson

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this EBM review is to determine whether or not a daily vitamin supplement is effective treatment for recurrent aphthous ulcers.

STUDY DESIGN: A review of 3 randomized control trials. All three trials are in English between 2009-2014.

DATA SOURCES: 3 randomized double blind placebo-controlled parallel-arm single center trials were found using PubMed.

OUTCOMES MEASURED: Each of the RCTs measured the efficacy of treatment for RAU in patients with aphthous ulcer outbreaks for at least a year or at least one to three outbreaks a month. This was performed by subjects of the study reporting on efficacy …

Is Botulinum Toxin A Safe And Effective For The Treatment Of Trigeminal Neuralgia In Adults?, Bryan Frank

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this evidence based medicine review is to determine whether or not Botulinum Toxin A is safe and effective for the treatment of trigeminal neuralgia in adults.

STUDY DESIGN: Three double blind, randomized controlled trials were reviewed and selected based on their relevance to the clinical question and their inclusion of patient oriented outcomes (POEMS).

DATA SOURCES: Each study was obtained by searching NCBI and PubMed database.

OUTCOMES MEASURED: The outcomes were measured using the Visual Analog Scale (VAS), Quality of Life (QoL), Patient Global Impression of Change Scale (PGIC), Last Observation Carried Forward (LOCF), and detected …

Is Topical Clonazepam More Effective Than Oral Clonazepam In Treatment Of Burning Mouth Syndrome (Bms)?, Sherley Casseus

PCOM Physician Assistant Studies Student Scholarship

Abstract not available.