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Articles 1 - 30 of 33
Full-Text Articles in Respiratory Tract Diseases
Health-Related Quality Of Life And Disease Severity Among Patients With Idiopathic Pulmonary Fibrosis, Rowida Mohamed
Health-Related Quality Of Life And Disease Severity Among Patients With Idiopathic Pulmonary Fibrosis, Rowida Mohamed
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background: Predicting the survival of patients with Idiopathic pulmonary fibrosis (IPF) remains challenging due to the remarkable heterogeneity of the disease prognosis. Therefore, developing reliable prognostic tools is of utmost importance in IPF management. Nomograms currently represent the most accurate and discriminatory tools for predicting outcomes, with superior performance compared to the commonly used integer score approach. Therefore, developing a valid local nomogram to predict mortality among patients with IPF is warranted. Additionally, IPF is characterized by a high symptom burden significantly impacting Health-related quality of life (HRQoL). Accurately measuring HRQoL in IPF is crucial as it guides treatment decisions …
Developing An Evaluation Process For Telehealth In A Copd Clinic, Jodi H. Biller
Developing An Evaluation Process For Telehealth In A Copd Clinic, Jodi H. Biller
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background: Telehealth was broadly implemented as a care modality in response to a worldwide pandemic in 2020. Before the COVID-19 pandemic, while telehealth was not new, it was not widely utilized at the project site location, and a uniform method of evaluating its effectiveness was needed. This quality assurance project developed and piloted a uniform process to evaluate telehealth in a Chronic Obstructive Pulmonary Disease (COPD) clinic, then evaluated stakeholder perceptions about the process used in developing the evaluation tool.
Methods: The telehealth evaluation tool was developed using the National Quality Forum (NQF) framework and Global Obstructive Lung Disease (GOLD) …
Understanding Vaccine-Induced Memory Responses To Develop The Next Generation Of Pertussis Vaccines, Kelly L. Weaver
Understanding Vaccine-Induced Memory Responses To Develop The Next Generation Of Pertussis Vaccines, Kelly L. Weaver
Graduate Theses, Dissertations, and Problem Reports (ETD)
Bordetella pertussis is a Gram-negative respiratory pathogen that can infect individuals of all ages and is notably responsible for infant fatalities. Pertussis (whooping cough) is a vaccine-preventable respiratory disease for which vaccines have been available in the United States since the 1940s. Whole cell pertussis vaccines kept incidence of pertussis under 5,000 cases per year, but were associated with reactogenicity issues. Following the introduction of less reactogenic acellular pertussis vaccines in the late 1990s, there have been noteworthy outbreaks of pertussis. For example, in 2012 there were over 50,000 reported cases of pertussis and 20 deaths in the U.S. The …
Understanding The Host Immune Response Against Pseudomonas Aeruginosa To Develop Novel Therapeutics And Vaccines, Emel Sen Kilic
Understanding The Host Immune Response Against Pseudomonas Aeruginosa To Develop Novel Therapeutics And Vaccines, Emel Sen Kilic
Graduate Theses, Dissertations, and Problem Reports (ETD)
Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that causes a broad range of acute and chronic infections. The high adaptability and emergence of multidrug-resistant strains of this bacterium pose a significant threat to human health. Particularly, pneumonia caused by this pathogen is associated with high morbidity and mortality in immunocompromised patients. To prevent these infections, we aimed to develop novel vaccine strategies by characterizing the host immune response against P. aeruginosa. During respiratory infections, P. aeruginosa first contacts with epithelial cells along the respiratory tract. Using RNA-sequencing, we were able to characterize transcriptional changes of the epithelial cells in …
Critical Physicochemical Properties For Nanoparticle Toxicity: Impact Of Surface Coating And Size On Particle-Induced Cell Transformation And Inflammatory Response, Tiffany Kornberg
Graduate Theses, Dissertations, and Problem Reports (ETD)
Nanoparticles, which measure 100 nm in at least one dimension, have surged in development, production, and use for a wide range of applications. However, the rapid pace of development for these emerging materials with unclear/unknown toxicity profiles makes it difficult to adequately assess health risk associated with exposure. One critical obstacle which limits scientific research to fill these critical knowledge gaps is the lack of accurate and predictive models for nanotoxicology studies, particularly those which involve occupationally relevant exposure scenarios (pulmonary exposure to low dose of particles in the circulating air). Typically, animal models are used to assess potential systemic …
Development Of Improved Acellular Pertussis Vaccines Through Inclusion Of The Rtx Antigen Or Induction Of Mucosal Immunity, Dylan Tyler Boehm
Development Of Improved Acellular Pertussis Vaccines Through Inclusion Of The Rtx Antigen Or Induction Of Mucosal Immunity, Dylan Tyler Boehm
Graduate Theses, Dissertations, and Problem Reports (ETD)
Pertussis is a human respiratory disease, primarily caused by the Gram-negative pathogen Bordetella pertussis. The infection is most severe and can be life-threatening in young children and infants where it manifests as a series of paroxysmal coughs. The disease is more commonly known as whooping cough, due to the whoop omitted during a massive inspiratory effort to bring air back into the lungs. Pertussis is a toxin-mediated disease that persists due to an early release of toxins that allow that bacteria to evade the cells of the innate immune response. The inhibition of the host response continues as toxin activity …
The Failed Promise Of Workplace Health Regulation, David C. Vladeck
The Failed Promise Of Workplace Health Regulation, David C. Vladeck
West Virginia Law Review
No abstract provided.
If Due Process Is A Big Tent, Why Do Some Feel Excluded From The Big Top, William S. Mattingly
If Due Process Is A Big Tent, Why Do Some Feel Excluded From The Big Top, William S. Mattingly
West Virginia Law Review
No abstract provided.
Black Lung Update: The Evolution Of The Current Regulations And The Proposed Revolution, William S. Mattingly
Black Lung Update: The Evolution Of The Current Regulations And The Proposed Revolution, William S. Mattingly
West Virginia Law Review
No abstract provided.
Modification Of Benefits For Claimants Under The Federal Black Lung Benefits Program, Rita A. Massie
Modification Of Benefits For Claimants Under The Federal Black Lung Benefits Program, Rita A. Massie
West Virginia Law Review
No abstract provided.
Is The Doctor Hostile--Obstructive Impairments And The Hostility Rule In Federal Black Lung Claims, Timothy F. Cogan
Is The Doctor Hostile--Obstructive Impairments And The Hostility Rule In Federal Black Lung Claims, Timothy F. Cogan
West Virginia Law Review
No abstract provided.
Director, Owcp V. Greenwich Collieries: The End Of The True Doubt Rule, Allan Brown
Director, Owcp V. Greenwich Collieries: The End Of The True Doubt Rule, Allan Brown
West Virginia Law Review
No abstract provided.
Federal Black Lung Update, William S. Mattingly
Federal Black Lung Update, William S. Mattingly
West Virginia Law Review
No abstract provided.
Federal Black Lung Update: The Standard Of Disability Causation For Federal Black Lung Benefits, Willaim S. Mattingley, Martin E. Hall
Federal Black Lung Update: The Standard Of Disability Causation For Federal Black Lung Benefits, Willaim S. Mattingley, Martin E. Hall
West Virginia Law Review
No abstract provided.
United States Department Of Labor V. Triplett: Black Lung Claimants Will Continue To Suffer From A Lack Of Legal Representation, Robert A. Campbell
United States Department Of Labor V. Triplett: Black Lung Claimants Will Continue To Suffer From A Lack Of Legal Representation, Robert A. Campbell
West Virginia Law Review
No abstract provided.
Federal Black Lung Update, Allen R. Prunty, Mark E. Solomons
Federal Black Lung Update, Allen R. Prunty, Mark E. Solomons
West Virginia Law Review
No abstract provided.
The Federal Black Lung Program: Its Evolution And Current Issues, Allen R. Prunty, Mark E. Solomons
The Federal Black Lung Program: Its Evolution And Current Issues, Allen R. Prunty, Mark E. Solomons
West Virginia Law Review
No abstract provided.
Can Coal Miners Escape Black Lung--An Analysis Of The Coal Miner Job Transfer Program And Its Implications For Occupational Medical Removal Protection Programs, Emily A. Spieler
Can Coal Miners Escape Black Lung--An Analysis Of The Coal Miner Job Transfer Program And Its Implications For Occupational Medical Removal Protection Programs, Emily A. Spieler
West Virginia Law Review
No abstract provided.
Stapleton V. Westmoreland Coal Company: Toward Making The Interim Presumption Irrebuttable, Michael D. Weikle
Stapleton V. Westmoreland Coal Company: Toward Making The Interim Presumption Irrebuttable, Michael D. Weikle
West Virginia Law Review
No abstract provided.
The Federal Black Lung Program--The View From The Top, Robert L. Ramsey, Robert S. Habermann
The Federal Black Lung Program--The View From The Top, Robert L. Ramsey, Robert S. Habermann
West Virginia Law Review
No abstract provided.
Black Lung Benefits Amendments Of 1981: Transfer Of Special Claims Under Section 205, James B. Stoneking
Black Lung Benefits Amendments Of 1981: Transfer Of Special Claims Under Section 205, James B. Stoneking
West Virginia Law Review
No abstract provided.
The Federal Black Lung Program: A 1983 Primer, John S. Lopatto Iii
The Federal Black Lung Program: A 1983 Primer, John S. Lopatto Iii
West Virginia Law Review
No abstract provided.
Recent Developments In Black Lung Litigation--Rebuttal Of The Interim Presumption, Tony Cicconi
Recent Developments In Black Lung Litigation--Rebuttal Of The Interim Presumption, Tony Cicconi
West Virginia Law Review
No abstract provided.
A Lawyer's Medical Guide To Black Lung Litigation, N. Leroy Lapp M.D.
A Lawyer's Medical Guide To Black Lung Litigation, N. Leroy Lapp M.D.
West Virginia Law Review
No abstract provided.
Counseling The Coal Miner Suffering From Respiratory Disease, Gail Falk
Counseling The Coal Miner Suffering From Respiratory Disease, Gail Falk
West Virginia Law Review
No abstract provided.
The Basics Of Federal Black Lung Litigation, Samuel J. Smith, Ford F. Newman
The Basics Of Federal Black Lung Litigation, Samuel J. Smith, Ford F. Newman
West Virginia Law Review
No abstract provided.
A Critical Analysis Of The Legislative History Surrounding The Black Lung Interim Presumption And A Survey Of Its Unresolved Issues, Mark E. Solomons
A Critical Analysis Of The Legislative History Surrounding The Black Lung Interim Presumption And A Survey Of Its Unresolved Issues, Mark E. Solomons
West Virginia Law Review
No abstract provided.
The Black Lung Benefits Act: An Operator's Perspective, J. Randolph Query
The Black Lung Benefits Act: An Operator's Perspective, J. Randolph Query
West Virginia Law Review
To be successful, attorneys must acquire certain basic skills and knowledge in their respective areas of expertise. Additionally, attorneys must participate in continuing legal education to maintain these basic skills and knowledge. This is especially true for federal black lung attorneys due to the dynamic nature of the law in this area. Federal black lung law has changed dramatically since the orginial enactment of Title IV of the Federal Coal Mine Health and Safety Act of 1969. Since its passage in December 1969, the Act has been substantially amended twice, first by the Black Lung Benefits Act of 1972 (BLBA), …
Closing The Evidentiary Gap: A Review Of Circuit Court Opinions Analyzing Federal Black Lung Presumptions Of Entitlement, Henry L. Stephens Jr., Alva A. Hollon Jr.
Closing The Evidentiary Gap: A Review Of Circuit Court Opinions Analyzing Federal Black Lung Presumptions Of Entitlement, Henry L. Stephens Jr., Alva A. Hollon Jr.
West Virginia Law Review
No abstract provided.
The Survivors' 25-Year Presumption Under The Black Lung Benefits Reform Act Of 1977: A Case For Its Unconstitutionality, David J. Millstone, Maria J. Codnach
The Survivors' 25-Year Presumption Under The Black Lung Benefits Reform Act Of 1977: A Case For Its Unconstitutionality, David J. Millstone, Maria J. Codnach
West Virginia Law Review
Title IV of the Federal Coal Mine Health and Safety Act of 1969 [the Black Lung Act], as amended by the Black Lung Benefits Reform Act of 1977 establishes, inter alia, a new presumption intended to substantially assist widows and other dependent survivors of coal miners in gaining benefits for disability caused by coal workers' pneumoconiosis (more commonly known as black lung disease). Survivors of coal miners who died before March 1, 1978, with twenty-five or more years of coal mine employment accrued prior to July 1, 1971, are presumed to be entitled to benefits unless it is established that, …