Male Urogenital Diseases Commons^™

Drug-Induced Acute Interstitial Nephritis Presenting As Severe Acute Kidney Injury Requiring Temporary Hemodialysis, Nihar Raju, Rohit Nair, Vaishnavi Singh, Veeranna Vibhuti

North Texas GME Research Forum 2026

Background: Acute interstitial nephritis (AIN) is an important but often underrecognized cause of acute kidney injury (AKI), accounting for 2–5% of all kidney biopsies and up to 20% of biopsies performed for AKI. Drug-induced AIN is the most common etiology in developed countries, frequently associated with antibiotics, nonsteroidal anti-inflammatory drugs, and proton pump inhibitors. Classic hypersensitivity features are frequently absent, leading to delayed diagnosis and increased risk of dialysis dependence.

Case Presentation: A 74-year-old male with a history of prostate cancer, type 2 diabetes mellitus, and hypertension presented with progressive exertional dyspnea and was found to have severe AKI without …

Tricenarian Seizure Cascade: Uremic Encephalopathy And Suspected Dialysis Disequilibrium, Purva Dahat, Jessica Nguyen, Sara Abuelayyan, Amnah Andrabi

North Texas GME Research Forum 2026

Introduction Uremic encephalopathy and dialysis disequilibrium syndrome (DDS) are distinct neurologic complications of renal failure that can precipitate seizures. While uremic encephalopathy reflects toxin-mediated metabolic dysfunction, DDS may occur during hemodialysis initiation from rapid osmotic shifts. They are usually described as separate entities, particularly in established CKD. Sequential neurologic events spanning the pre-dialysis period and dialysis initiation in previously undiagnosed renal failure are poorly characterized.

Case presentation A previously healthy African American man in his 30s with no known history of kidney disease presented with new-onset generalized tonic-clonic seizure accompanied by respiratory distress. Initial laboratory testing revealed profound azotemia with …

Navigating Recurrent Hematuria In Vesicular Varices: A Case Of Successful Multidisciplinary Intervention, Morgan Grosdidier, Muiz Khan Tareen, Danielle Ford

North Texas GME Research Forum 2026

Background Hematuria secondary to vesicular varices is a rare but serious complication of portal hypertension, often associated with liver cirrhosis. Effective management requires a multidisciplinary approach, often involving urology, gastroenterology, and interventional radiology to address acute bleeding and prevent recurrence.

Case Presentation We present a case of a patient with alcoholic liver cirrhosis who experienced severe hematuria, highlighting the diagnostic and therapeutic challenges encountered. The patient presented with a two-day history of acute hematuria and blood clots, ultimately attributed to vesicular varices secondary to portal hypertension from alcoholic liver cirrhosis. Urology was consulted, who recommended continuous bladder irrigation (CBI), initially …

True Love: Heart Says To The Kidneys ‘Don’T Fail Me’, Greeshma Molugu, Srinivasan Rajaganapathy, Machaiah Madhrira

North Texas GME Research Forum 2026

Introduction: Valvular calcification is an increasingly important cardiac valvular pathology in end-stage renal disease (ESRD) patients, most frequently involving the aortic and mitral valves. The incidence/prevalence of mitral annular calcification in ESRD patients is about 30%, with mitral stenosis occurring in less than 5%. Various predisposing factors for valvular calcification in ESRD patients include age (median age >/= 60 years), hypertension, diabetes, use of calcitriol and calcium-containing phosphate binders, secondary hyperparathyroidism and duration of dialysis (median duration of >/= 5 years). We present a rare case of a young male with ESRD on peritoneal dialysis (PD) for less than two …

A Storm At Both Ends: Hypertensive Emergency Unmaksing C3-Dominant Glomerulonephritis, Karthik Kasireddy, Boney Lapsiwala, Marisha Sharma, Rupali Prabhukhot, Victor Canela

North Texas GME Research Forum 2026

Background: C3 glomerulopathy (C3G) encompasses a group of diseases that result from abnormalities in the alternative pathway of complement regulation, and has been defined by C3 only or C3-dominant immunofluorescence staining seen on renal biopsy. C3G includes C3 glomerulonephritis (C3GN) and dense deposit disease (DDD); the latter of which is characterized ultra-structurally by the presence of highly osmiophilic intramembranous deposits. Both C3GN and DDD often present with a membranoproliferative pattern of glomerular injury, a finding that can also be seen in thrombotic microangiopathy (TMA). Most common causes include infection, autoimmune and monoclonal gammopathy.

Case presentation: A 70-year-old man with hypertension, …