Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Biology (2)
- Life Sciences (2)
- Amino Acids, Peptides, and Proteins (1)
- Biochemistry (1)
- Biochemistry, Biophysics, and Structural Biology (1)
-
- Cell Biology (1)
- Cell and Developmental Biology (1)
- Chemical Actions and Uses (1)
- Chemicals and Drugs (1)
- Computational Biology (1)
- Digestive System Diseases (1)
- Genetics and Genomics (1)
- Immune System Diseases (1)
- Laboratory and Basic Science Research (1)
- Nursing (1)
- Nutritional and Metabolic Diseases (1)
- Other Genetics and Genomics (1)
- Other Life Sciences (1)
- Public Health (1)
- Research Methods in Life Sciences (1)
- Respiratory Tract Diseases (1)
- Skin and Connective Tissue Diseases (1)
- Structural Biology (1)
- Virus Diseases (1)
Articles 1 - 3 of 3
Full-Text Articles in Disease Modeling
Exploring The Ipf Lung Through The Lens Of Single Cell Rna Sequencing, Taylor Adams, Jonas Schupp
Exploring The Ipf Lung Through The Lens Of Single Cell Rna Sequencing, Taylor Adams, Jonas Schupp
Yale Day of Data
This poster illustrates the differences between the IPF disease-specific variety of lung macrophages and the two varieties of macrophages known to reside in the normal human lung.
Studies Of Amino Acid Mutations In Drug Resistance Of The Smo Protein, Eunice Wintona
Studies Of Amino Acid Mutations In Drug Resistance Of The Smo Protein, Eunice Wintona
UNO Student Research and Creative Activity Fair
Smoothened receptor (SMO) is a protein that in humans, is encoded by the SMO gene. A systemic mutation in its binding pocket helps predict the sensitivity of mutant proteins to different drugs. Known as a GPCR-like receptor, it is a component of the hedgehog signaling pathway; a pathway involved in body patterning and the regulation of adult stem cells. An uncontrolled or inappropriate activation of the Hedgehog pathway drives tumor progression in cancers and a number of birth defects. To achieve these goals, the molecular modeling software MOE was used to build small molecules and drug molecules like Vismodegib and …
Modification Of The Ruiz-Moreno Chikungunya Seir Model, Joseph Devlin
Modification Of The Ruiz-Moreno Chikungunya Seir Model, Joseph Devlin
UNO Student Research and Creative Activity Fair
The Ruiez-Moreno CHIKV model predicts the outcome of the Chikungunya disease. Chikungunya, a disease similar to the Zika virus, is vector-borne with very little treatment for patients. This experiment looks to find ways to improve the model. The model will still need further improvement, as there is no model that can predict with full certainty. However, a method of modification has been made to expedite the process, the code has been rearranged for easy input and to minimize possibility of unwanted changes, and the control files for comparison have been created. The method to modify the model can be superimposed …