Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Specialties (18)
- Cardiology (15)
- Public Health (11)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (8)
- Health Services Research (7)
-
- Nursing (7)
- Pathological Conditions, Signs and Symptoms (7)
- Health and Medical Administration (4)
- Internal Medicine (4)
- Life Sciences (4)
- Therapeutics (4)
- Diagnosis (3)
- Medical Education (3)
- Medical Sciences (3)
- Anatomy (2)
- Biostatistics (2)
- Cardiovascular System (2)
- Chemicals and Drugs (2)
- Clinical Epidemiology (2)
- Community Health and Preventive Medicine (2)
- Critical Care (2)
- Critical Care Nursing (2)
- Education (2)
- Emergency Medicine (2)
- Epidemiology (2)
- Human and Clinical Nutrition (2)
- Nutrition (2)
- Institution
-
- Rowan University (5)
- Selected Works (5)
- Philadelphia College of Osteopathic Medicine (3)
- University of Kentucky (3)
- Otterbein University (2)
-
- The Texas Medical Center Library (2)
- University of Texas Rio Grande Valley (2)
- Virginia Commonwealth University (2)
- Children's Mercy Kansas City (1)
- Eastern Kentucky University (1)
- HCA Healthcare (1)
- Harding University (1)
- Hong Kong College of Cardiology (1)
- Medical University of South Carolina (1)
- Ohio Northern University (1)
- Purdue University (1)
- Sacred Heart University (1)
- Touro College and University System (1)
- University of Massachusetts Amherst (1)
- University of San Diego (1)
- University of South Carolina (1)
- University of Tennessee Health Science Center (1)
- Publication Year
- Publication
-
- Rowan-Virtua Research Day (5)
- Jorge L. Yarzebski (4)
- DNP Projects (3)
- PCOM Physician Assistant Studies Student Scholarship (3)
- Journal Articles (2)
-
- Nursing Student Class Projects (Formerly MSN) (2)
- Theses and Dissertations (2)
- Capital Division Research Day 2023 (1)
- College of Pharmacy Faculty Research and Publications (1)
- Doctor of Nursing Practice (DNP) Projects (1)
- Doctor of Nursing Practice Final Manuscripts (1)
- Doctor of Nursing Practice Projects (1)
- Jennifer Tjia (1)
- Journal of the Hong Kong College of Cardiology (1)
- MUSC Theses and Dissertations (1)
- Manuscripts, Articles, Book Chapters and Other Papers (1)
- Office of the President Publications and Research (1)
- Online Theses and Dissertations (1)
- Pharmacy and Wellness Review (1)
- Research Colloquium (1)
- Research Symposium (1)
- Senior Theses (1)
- The Summer Undergraduate Research Fellowship (SURF) Symposium (1)
- Theses and Dissertations--Physiology (1)
- Publication Type
- File Type
Articles 1 - 30 of 38
Full-Text Articles in Cardiovascular Diseases
Effects Of Obesity On Patients Undergoing Cardiomems Procedure: Retrospective Cohort Study, Tony Elias, Mena Elmalh, Priya Brahmbhatt, Kyrillos Girgis, Taha Syed, Michael Valderrama, Rafail Beshai
Effects Of Obesity On Patients Undergoing Cardiomems Procedure: Retrospective Cohort Study, Tony Elias, Mena Elmalh, Priya Brahmbhatt, Kyrillos Girgis, Taha Syed, Michael Valderrama, Rafail Beshai
Rowan-Virtua Research Day
★ Remote hemodynamic monitoring (CardioMEMs) is becoming increasingly important for management of chronic heart failure patients.
★ There is limited data looking specifically for obese patients who undergo CardioMEMs implantation.
★ We sought to examine the national inpatient sample database to describe in-hospital outcomes for this demographic
Sex Differences In Outcomes Among Patients With High-Output Heart Failure: A Retrospective Cohort Study, Tony Elias, Mena Elmalh, Priya Brahmbhatt, Kyrillos Girgis, Taha Syed, Michael Valderrama, Rafail Beshai
Sex Differences In Outcomes Among Patients With High-Output Heart Failure: A Retrospective Cohort Study, Tony Elias, Mena Elmalh, Priya Brahmbhatt, Kyrillos Girgis, Taha Syed, Michael Valderrama, Rafail Beshai
Rowan-Virtua Research Day
❖ There is limited data specifically looking for sex differences in patients with high output heart failure (HOHF).
❖ We sought to examine the national inpatient sample database to describe in-hospital outcomes among female patients.
Clinical Outcomes For Impella Patients Associated With Hyperlipidemia: An Analysis Of The National Inpatient Sample, Tony Elias, Sonika Vatsa, Kyrillos Gamal, Taha Syed, Rafail Beshai
Clinical Outcomes For Impella Patients Associated With Hyperlipidemia: An Analysis Of The National Inpatient Sample, Tony Elias, Sonika Vatsa, Kyrillos Gamal, Taha Syed, Rafail Beshai
Rowan-Virtua Research Day
The Impella, a ventricular assist device, is crucial for managing severe heart failure and cardiogenic shock. Despite its widespread use, there's scant information on how hyperlipidemia affects Impella patients. To address this gap, we delved into the National Inpatient Sample Database from 2019 and 2020. Our aim was to scrutinize in-hospital outcomes among these patients. We identified 8233 Impella patients, among whom 1012 (12.3%) had hyperlipidemia. Those with hyperlipidemia displayed higher rates of hypertension, diabetes mellitus, and chronic kidney disease compared to their counterparts without hyperlipidemia. Shockingly, in-hospital mortality was notably elevated in the hyperlipidemia group, emphasizing its clinical significance. …
Improving Nutrition Screening Practice In The Hospitalized Heart Failure Patient Population, Amanda J. Bourgeois
Improving Nutrition Screening Practice In The Hospitalized Heart Failure Patient Population, Amanda J. Bourgeois
DNP Projects
Background: Heart Failure is a disease known to affect nearly 6.5 million adults in the United States. Characterized by recurrent hospitalizations, heart failure significantly contributes to morbidity, mortality, and healthcare costs in the United States and worldwide. Because malnutrition is prevalent in the heart failure population, healthcare providers must perform nutritional assessments on admission to intervene in the case of malnutrition, prevent deterioration, and improve patient prognosis. Without intervention and early identification of malnutrition, heart failure hospitalizations will remain a significant problem.
Purpose: The purpose of this study is to evaluate the effect of an evidence-based educational program for cardiac …
A Case Of Device Lead Induced Severe Tricuspid Regurgitation And Right-Sided Heart Failure, Nina Shyama Appareddy, Michaela Iglesia, Ayman Khaddam, Henry Kwang, Eduardo D. Flores
A Case Of Device Lead Induced Severe Tricuspid Regurgitation And Right-Sided Heart Failure, Nina Shyama Appareddy, Michaela Iglesia, Ayman Khaddam, Henry Kwang, Eduardo D. Flores
Research Colloquium
Background: Interference of device leads with closure of the tricuspid leaflets can cause severe tricuspid regurgitation (TR) and right-sided heart failure, as can heart failure with reduced LV function (HfrEF), and left sided valve disease.
Case Presentation: A 78-year-old male with history of coronary artery disease s/p remote coronary bypass, ischemic cardiomyopathy with left ventricular ejection fraction 35-40%, and inducible ventricular tachycardia status post defibrillator presented with worsening dyspnea on exertion, easy fatigue, lower extremity pitting edema, anasarca, abdominal bloating and new systolic murmurs at the right upper and left lower sternal borders. An Echocardiogram demonstrated severe aortic stenosis with …
Taking The Load Off: Device Lead-Induced Severe Tricuspid Regurgitation And Right-Sided Heart Failure Treated With Transcatheter Aortic Valve Implantation (Tavi), Nina Shyama Appareddy, Michaela Iglesia, Ayman Khaddam, Henry Kwang, Eduardo Flores
Taking The Load Off: Device Lead-Induced Severe Tricuspid Regurgitation And Right-Sided Heart Failure Treated With Transcatheter Aortic Valve Implantation (Tavi), Nina Shyama Appareddy, Michaela Iglesia, Ayman Khaddam, Henry Kwang, Eduardo Flores
Research Symposium
Background: Interference of device leads with closure of the tricuspid leaflets can cause severe tricuspid regurgitation (TR) and right-sided heart failure, as can heart failure with reduced ejection fraction (HFrEF) and left sided valve disease. We report a case treated with transcatheter aortic valve implantation (TAVI) with improved TR.
Case: A 78-year-old male with coronary artery disease status post remote myocardial infarction and coronary bypass, HFrEF with left ventricular ejection fraction 35-40%, and inducible ventricular tachycardia status post AICD placement presented with worsening dyspnea on exertion, easy fatigue, lower extremity edema, anasarca and abdominal bloating. Transthoracic echocardiography demonstrated severe aortic …
A Two-Step Transcriptome Analysis Of The Human Heart Reveals Broad And Disease-Responsive Expression Of Ectopic Olfactory Receptors., Sadia Ashraf, O Howard Frazier, Sylvia Carranza, David D Mcpherson, Heinrich Taegtmeyer, Romain Harmancey
A Two-Step Transcriptome Analysis Of The Human Heart Reveals Broad And Disease-Responsive Expression Of Ectopic Olfactory Receptors., Sadia Ashraf, O Howard Frazier, Sylvia Carranza, David D Mcpherson, Heinrich Taegtmeyer, Romain Harmancey
Journal Articles
G-protein-coupled receptors (GPCRs) are critical regulators of cardiac physiology and a key therapeutic target for the treatment of heart disease. Ectopic olfactory receptors (ORs) are GPCRs expressed in extra-nasal tissues which have recently emerged as new mediators in the metabolic control of cardiac function. The goals of this study were to profile OR gene expression in the human heart, to identify ORs dysregulated by heart failure caused by ischemic cardiomyopathy, and to provide evidence suggestive of a role for those altered ORs in the pathogenesis of heart failure. Left ventricular tissue from heart failure patients (
Mixed Beri’S: High Output Heart Failure From Severe Anemia And Thiamine Deficiency, Rohan Umrani, Hiral Amin, Ashley Pinckney, Charles Yang, Daniel Tran
Mixed Beri’S: High Output Heart Failure From Severe Anemia And Thiamine Deficiency, Rohan Umrani, Hiral Amin, Ashley Pinckney, Charles Yang, Daniel Tran
Rowan-Virtua Research Day
Background: Severe anemia and thiamine deficiency can independently result in high output heart failure (HOHF) through different mechanisms. Data on the threshold and timeframe at which these etiologies may precipitate HOHF is unclear.
Case: A 63-year-old male with alcohol use disorder consuming 18 drinks/week presented with progressive shortness of breath and lower extremity edema for a few months. Physical exam revealed tachycardia, anasarca, jugular venous distension, Lancisi’s sign, and a midsystolic murmur. Echocardiogram demonstrated EF of 30-35%, dilated left ventricle, and cardiac index of 4.2L/min/m2.
Decision-Making: Heart failure can independently precipitate anemia while severe alcoholism can induce myelosuppression and promote …
Spontaneous Iliac Arteriovenous Fistula, High-Output Heart Failure, And Cardiac Arrest, J. Maxwell Piraneo, Russell Mordecai, James Espinosa, Alan Lucerna
Spontaneous Iliac Arteriovenous Fistula, High-Output Heart Failure, And Cardiac Arrest, J. Maxwell Piraneo, Russell Mordecai, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
High-output heart failure is a potentially life-threatening condition that can lead to cardiac arrest. The most common causes of this condition are obesity, liver disease, arteriovenous shunts, lung disease, and myeloproliferative disorders, however the exact prevalence remains uncertain [1]. Here we describe an unusual case of cardiac arrest as a consequence of high-output heart failure, secondary to rupture of an iliac artery aneurysm into the common iliac vein, with arteriovenous (AV) fistula formation.
Role Of Macrophages In Regression Of Myocardial Fibrosis Following Alleviation Of Left Ventricular Pressure Overload, Lily Neff
MUSC Theses and Dissertations
Antecedent conditions that affect the heart, such as aortic stenosis (AS), can develop into left ventricular pressure overload (LVPO). LVPO is associated with increased myocardial interstitial fibrosis, specifically fibrillar collagen, that leads to increased myocardial stiffness. Patients undergoing surgical aortic valve replacement (SAVR) to correct AS demonstrate significant but incomplete regression of fibrosis. Although current therapies normalize hemodynamic load, treatments that regress collagen content within the myocardium remain a critical need. To elucidate cellular mechanisms of this persistent fibrosis in LVPO, we utilized a transverse aortic constriction (TAC) and removal of the constriction (unTAC) murine model. Outputs were assessed for: …
Heart Failure With Preserved Ejection Fraction Management Current Literature Review, Gregory Carbonella, Peter Dourdoufis
Heart Failure With Preserved Ejection Fraction Management Current Literature Review, Gregory Carbonella, Peter Dourdoufis
Capital Division Research Day 2023
No abstract provided.
29th Annual Scientific Congress Of Hong Kong College Of Cardiology Abstracts
29th Annual Scientific Congress Of Hong Kong College Of Cardiology Abstracts
Journal of the Hong Kong College of Cardiology
No abstract provided.
Heart Failure, Molly Davis
Heart Failure, Molly Davis
Nursing Student Class Projects (Formerly MSN)
Heart Failure is defined as the pathophysiologic condition in which the heart is unable to generate an adequate cardiac output such that perfusion of tissues or increased diastolic filling pressure of the left ventricle, or both occurs (Huether & McCance, 2019).
Perioperative Risks Of The Patient With Heart Failure, Gabrielle Metoyer
Perioperative Risks Of The Patient With Heart Failure, Gabrielle Metoyer
Nursing Student Class Projects (Formerly MSN)
Perioperative Risks of the Patient with Heart Failure
Gabrielle Metoyer
Department of Nursing, Otterbein University
NURS 6810 – Advanced Pathophysiology
Dr. Deanna Batross and Dr. Shivani Bhatnagar
August 5, 2022
Abstract
According to the CDC (2020), heart failure occurs when the heart cannot pump enough blood and oxygen to support other organs in your body. Heart failure is an epidemic disease affecting 1-2% of the population worldwide (Schwinger, 2020). It is one of the leading causes of morbidity and mortality worldwide with an estimated 6.5 million adults with heart failure in the United States (Lo et al., 2021). Medical advances …
Prolonged Cardiac Nr4a2 Activation Causes Dilated Cardiomyopathy In Mice., Sadia Ashraf, Heinrich Taegtmeyer, Romain Harmancey
Prolonged Cardiac Nr4a2 Activation Causes Dilated Cardiomyopathy In Mice., Sadia Ashraf, Heinrich Taegtmeyer, Romain Harmancey
Journal Articles
Transcription factors play a fundamental role in cardiovascular adaptation to stress. Nuclear receptor subfamily 4 group A member 2 (NR4A2; NURR1) is an immediate-early gene and transcription factor with a versatile role throughout many organs. In the adult mammalian heart, and particularly in cardiac myocytes, NR4A2 is strongly up-regulated in response to beta-adrenergic stimulation. The physiologic implications of this increase remain unknown. In this study, we aimed to interrogate the consequences of cardiac NR4A2 up-regulation under normal conditions and in response to pressure overload. In mice, tamoxifen-dependent, cardiomyocyte-restricted overexpression of NR4A2 led to cardiomyocyte hypertrophy, left ventricular dilation, heart failure, …
Improving Heart Failure Patient Referrals To The Center For Advanced Heart Failure & Pulmonary Vascular Disease At Hartford Hospital: A Quality Improvement Project, Dawn M. Surprenant
Improving Heart Failure Patient Referrals To The Center For Advanced Heart Failure & Pulmonary Vascular Disease At Hartford Hospital: A Quality Improvement Project, Dawn M. Surprenant
DNP Projects
Significance and Background: According to the Health Resources & Services Administration (2021), health literacy is the degree to which individuals have the capacity to process and understand basic health information to make appropriate health decisions. Low health literacy is prevalent in populations such as older adults, minorities, and in individuals with lower socioeconomic status and living in medical underserved areas. Recommendations are to access health literacy in cardiac patients, especially in the acute care setting to improve health outcomes upon discharge.
Purpose: To determine whether a health literacy assessment in hospitalized congested heart failure patients, before discharge, will affect referral …
The Effects Of Interleukin-1Β On Cardiac Reserve And Exercise Capacity In The Mouse, Habeebah Z. Vohra
The Effects Of Interleukin-1Β On Cardiac Reserve And Exercise Capacity In The Mouse, Habeebah Z. Vohra
Theses and Dissertations
Heart failure (HF) is characterized by dyspnea, fatigue, and exercise intolerance. Clinical evidence points to increased interleukin-1β (IL-1β) activity in patients with HF, with an IL-1 blockade improving the exercise capacity in HF patients. In healthy mice, recombinant-mouse IL-1β (rmIL-1β) induces acute systolic dysfunction, peaking 4 hours after administration. However, the direct effects of rmIL-1β on exercise capacity are unknown. We hypothesized that rmIL-1β diminishes the exercise capacity in the mouse. Adult mice were trained to run on a treadmill and exercise capacity was assessed before, 4 hours, and 96 hours after intraperitoneal administration of rmIL-1β (3 μg/kg) or vehicle …
Rad Modulation Of The L-Type Calcium Channel Confers Systolic Advantage In The Heart, Brooke Mildred Ahern
Rad Modulation Of The L-Type Calcium Channel Confers Systolic Advantage In The Heart, Brooke Mildred Ahern
Theses and Dissertations--Physiology
Heart failure is a major public health problem and a leading cause of mortality. This clinical condition affects populations of all ages, and is the result of various cardiomyopathies. Almost half of these patients suffer specifically from heart failure with reduced ejection fraction; these hearts have decreased performance due to a failure of the heart to contract with sufficient force to meet demand. While there are therapies available to increase contractility, none of these enhance contraction without also further promoting pathological signaling and remodeling.
Under normal physiological conditions, the body elevates cardiac output through the fight-or-flight response. This response activates …
Heart Failure 30-Day Readmission Frequency, Rates, And Hf Classification, Yolanda R. Brown, Twonia M. Goyer, Margaret C. Harvey
Heart Failure 30-Day Readmission Frequency, Rates, And Hf Classification, Yolanda R. Brown, Twonia M. Goyer, Margaret C. Harvey
Doctor of Nursing Practice Projects
30 Day Hospital Readmission Rates, Frequencies, and Heart Failure Classification for Patients with Heart Failure
Background Congestive heart failure (CHF) is the leading cause of mortality, morbidity, and disability worldwide among patients. Both the incidence and the prevalence of heart failure are age dependent and are relatively common in individuals 40 years of age and older. CHF is one of the leading causes of inpatient hospitalization readmission in the United States, with readmission rates remaining above the 20% goal within 30 days. The Center for Medicare and Medicaid Services imposes a 3% reimbursement penalty for excessive readmissions including those who …
The Usefulness Of The Left Atrial Dilation Rate In Determining Severity Of Heart Failure, Laura B. Snyder
The Usefulness Of The Left Atrial Dilation Rate In Determining Severity Of Heart Failure, Laura B. Snyder
Senior Theses
Hypertension and vascular stiffness are two physiological conditions that strain the left ventricle (LV) and cause it to gain muscle mass. Eventually, the LV is unable to fill correctly and the patient develops Heart Failure with a preserved Ejection Fraction (HFpEF). Clinically, a patient’s left atrium (LA) area is measured as a diagnostic parameter of HFpEF severity. However, this doesn’t offer a prognosis or threshold of LA size necessitating hospitalization because of variation in patient demographics, genetics, and lifestyle which affect rates of HFpEF progression.
Since there are no medications or effective treatment options for HFpEF patients, there is a …
Combined Neprilysin And Angiotensin Inhibitor For The Treatment Of Heart Failure, Albert Bui, Victoria Cho, Rebecca Worden, Haley Armstrong, Rachel Pucel, Lindsey Peters
Combined Neprilysin And Angiotensin Inhibitor For The Treatment Of Heart Failure, Albert Bui, Victoria Cho, Rebecca Worden, Haley Armstrong, Rachel Pucel, Lindsey Peters
Pharmacy and Wellness Review
Heart failure (HF) is a highly prevalent disease state worldwide that can progress into a disabling condition. It is pertinent to have a treatment regimen that is effective in lowering the number of HF exacerbations and, therefore, hospital readmission rates. A novel medication currently in clinical trials, LCZ696, blocks both neprilysin and angiotensin type I receptors. The overall effects are an inhibition of the breakdown of natriuretic peptides which leads to a decrease in renin and aldosterone release. This, combined with the antagonization of angiotensin type I receptors, leads to a decrease in blood pressure, blood volume and systemic vascular …
Nurse-Led Positive Psychology Intervention Is Feasible In Patients With Heart Failure, Erin Taylor
Nurse-Led Positive Psychology Intervention Is Feasible In Patients With Heart Failure, Erin Taylor
DNP Projects
Introduction: Prevalence of heart failure (HF) in the US is projected to rise 46% by 2030, resulting in more than 8 million people with HF. Negative psychologic states including depression and pessimism (negative future expectations) have been linked with poor cardiovascular outcomes, including HF. Despite the fact that optimism (positive future expectations) and other positive affective states have been associated with superior outcomes, there has been little focus on interventions designed to increase positive psychological states in patients with HF.
Objective: To test the acceptability and feasibility of a nurse-led positive psychology intervention, Best Possible Self (BPS).
Methods: A convenience …
Incidence And Predictor Variables Of Pressure Injuries In Patients Undergoing Ventricular Assist Device And Total Artificial Heart Surgeries: An Eight-Year Retrospective Review, Christopher T. Brindle
Incidence And Predictor Variables Of Pressure Injuries In Patients Undergoing Ventricular Assist Device And Total Artificial Heart Surgeries: An Eight-Year Retrospective Review, Christopher T. Brindle
Theses and Dissertations
BACKGROUND
Cardiac surgery patients have some of the highest reported incidence and prevalence of pressure injuries (PI). A growing subset of cardiac surgery include patients with end-stage heart failure who undergo ventricular assist device (VAD) or total artificial heart (TAH) surgery. The risk of PI and their natural history of development in this population are unknown and the specific risk factors for PI development remain unexplored.
OBJECTIVES
To perform a systematic review of the literature to identify the incidence and risk factors of PI development in patients undergoing VAD-TAH surgery and thereby inform study design and variables in an eight-year …
Rationale And Design Of The Children's Oncology Group (Cog) Study Alte1621: A Randomized, Placebo-Controlled Trial To Determine If Low-Dose Carvedilol Can Prevent Anthracycline-Related Left Ventricular Remodeling In Childhood Cancer Survivors At High Risk For Developing Heart Failure., Saro H. Armenian, Melissa M. Hudson, Ming Hui Chen, Steven D. Colan, Lanie Lindenfeld, George Mills, Aida Siyahian, Sarah Gelehrter, Ha Dang, Wendy Hein, Daniel M M. Green, Leslie L. Robison, F Lennie Wong, Pamela S. Douglas, Smita Bhatia
Rationale And Design Of The Children's Oncology Group (Cog) Study Alte1621: A Randomized, Placebo-Controlled Trial To Determine If Low-Dose Carvedilol Can Prevent Anthracycline-Related Left Ventricular Remodeling In Childhood Cancer Survivors At High Risk For Developing Heart Failure., Saro H. Armenian, Melissa M. Hudson, Ming Hui Chen, Steven D. Colan, Lanie Lindenfeld, George Mills, Aida Siyahian, Sarah Gelehrter, Ha Dang, Wendy Hein, Daniel M M. Green, Leslie L. Robison, F Lennie Wong, Pamela S. Douglas, Smita Bhatia
Manuscripts, Articles, Book Chapters and Other Papers
Background: Anthracyclines are widely used in the treatment of childhood cancer. One of the well-recognized side-effects of anthracycline therapy is dose-dependent cardiomyopathy that may progress to heart failure (HF) years after completion of cancer-directed therapy. This study will evaluate the efficacy of low-dose beta-blocker (carvedilol) for HF risk reduction in childhood cancer survivors at highest risk for HF. The proposed intervention has the potential to significantly reduce chronic cardiac injury via interruption of neurohormonal systems responsible for left ventricular (LV) remodeling, resulting in improved cardiac function and decreased risk of HF. The intervention is informed by previous studies demonstrating efficacy …
Pathway By Which Vagus Nerve Stimulation Of B Fibers Affects Heart Rate, Kelsey Wasilczuk, Matthew Ward, Pedro Irazoqui
Pathway By Which Vagus Nerve Stimulation Of B Fibers Affects Heart Rate, Kelsey Wasilczuk, Matthew Ward, Pedro Irazoqui
The Summer Undergraduate Research Fellowship (SURF) Symposium
Heart failure (HF) affects over 5 million adults in the United States. Many HF patients have a high resting heart rate, which is correlated with a high mortality rate. In recent years, vagus nerve stimulation (VNS) has become an increasingly researched therapy to reduce the resting heart rate of HF patients. However, current dosage given during VNS is increased incrementally at the doctor’s office until side effects present themselves in a patient. In addition, the means by which the therapy works is not completely understood. To better understand the therapy’s mechanisms, the right cervical vagus nerve of several Long Evans …
Drug-Induced Nutrient Depletion, Rodney Richmond
Drug-Induced Nutrient Depletion, Rodney Richmond
College of Pharmacy Faculty Research and Publications
No abstract provided.
A Structured Telephonic Transition Program For Heart Failure Patients, Julia E. Robinson
A Structured Telephonic Transition Program For Heart Failure Patients, Julia E. Robinson
Doctor of Nursing Practice Final Manuscripts
HF is a fatal condition affecting more than 5 million Americans leading to frequent hospitalizations, poor quality of life and death. The annual cost to the healthcare system is approximately $38 billion, ranking HF as one of the costliest conditions to manage. Significant evidence exists that HF self-care management programs improve patient self-care and decrease HF-related readmissions. Current guidelines recommend health professionals provide comprehensive HF education focused on knowledge, skills of management, and self-care behaviors.
The Iowa Model of Evidence Based Practice provided the foundation for the practice change. Structured telephonic support (STS) was based on Bandura’s Self- Efficacy behavior …
Does Ivabradine Improve Quality Of Life In Cardiovascular Disease Patients?, Daniel E. Lynch
Does Ivabradine Improve Quality Of Life In Cardiovascular Disease Patients?, Daniel E. Lynch
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this review is to determine whether ivabradine therapy can improve the quality of life in cardiovascular disease patients.
Study Design: The studies included in this review are one randomized control study and two double blind randomized control studies from 2008, 2010, and 2012.
Data Source: The three studies in this review were obtained by performing a PubMed search using the keywords “ivabradine” and random control trial.” All articles were published in English and in peer-reviewed journals.
Outcomes Measured: The three studies ascertained whether there was a decrease in hospitalization events within coronary artery disease and heart …
Molecular Basis Of Sex Differences In Cardiac Hypertrophy And Heart Failure, Maya James
Molecular Basis Of Sex Differences In Cardiac Hypertrophy And Heart Failure, Maya James
Online Theses and Dissertations
Transforming growth factor beta ligands and receptors are known to be pro-hypertrophic and pro-fibrotic factors in the heart, and are known to contribute to the development of cardiac hypertrophy and heart failure. It is well established that premenopausal females possess a lower incidence of these pathologies. We and others have observed a greater level of fibrosis in male hearts compared to female hearts in rodent models of cardiac hypertrophy. It is well established that estrogen is cardioprotective in that it can prevent the development of cardiac hypertrophy, as well as abrogate the development of heart failure following sustained cardiac hypertrophy. …
Is Vitamin D Supplementation Effective In Improving Physical Performance In Older Patients With Heart Failure Who Are Over The Age Of 50 Years?, Sahba Yazdani
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not vitamin D supplement is effective in improving physical performance in older patients with heart failure over the age 50 years
STUDY DESIGN: Review of three English language primary studies, two published in 2010 and one was published in 2013.
DATA SOURCES: Two double blind randomized controlled trials (RCT) and one cross-sectional study that investigated the use of vitamin D in improving physical performance in heart failure. Sources were selected and found using PubMed, ScienceDirect, and Cochrane databases.
OUTCOMES MEASURED: The outcomes measured were improvement of physical …