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Bacterial Infections and Mycoses Commons™
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Articles 1 - 9 of 9
Full-Text Articles in Bacterial Infections and Mycoses
Comparative Investigation Of Bacterial Adhesion On Medical Device Thermoplastics, Dev V. Mehta
Comparative Investigation Of Bacterial Adhesion On Medical Device Thermoplastics, Dev V. Mehta
Honors Theses
This project will focus on determining if differences in bacterial cell wall composition influences adhesiveness to thermoplastic materials used to construct patient orthotic splints. Bacteria with decreased adhesion are unable to remain bonded to orthotic splints, increasing its ability to transfer to a patient’s wound, leading to an infection. Antibiotic resistant bacteria used in this investigation included gram-positive cocci vancomycin-resistant (VRE) Enterococcus faecalis, methicillin-resistant Staphylococcus aureus (MRSA), and gram-negative rods extended-spectrum beta-lactamase (ESBL) Escherichia coli and Pseudomonas aeruginosa. Each test bacterium is a major pathogen causing healthcare-associated infections (HAIs). Saline, artificial perspiration, and ascites fluids were used to determine the …
Investigating The Synthesis And Antibacterial Activity Of A Main-Chain Cationic Polymer, Emily Smith
Investigating The Synthesis And Antibacterial Activity Of A Main-Chain Cationic Polymer, Emily Smith
Honors Theses
Antibiotic resistance is a growing threat to public health. Due to the overuse of antibiotics in agriculture, the overprescription of antibiotics, and the misuse of antibiotics by patients, antibiotic resistance is spreading at an alarming rate. As antibiotic resistance spreads, the antibiotics we depend on to treat common infections become ineffective. Therefore, it is imperative to develop novel treatments for infections that do not increase the prevalence of antibiotic resistance. One treatment being explored is the use of synthetic polymers with antibacterial properties. Synthetic polymers are advantageous because they can be synthesized from widely available precursors and their structure is …
Prevalence Of Potentially Pathogenic Bacteria In Showers At A Long-Term Nursing Care Facility, Joseph Caleb Kulon
Prevalence Of Potentially Pathogenic Bacteria In Showers At A Long-Term Nursing Care Facility, Joseph Caleb Kulon
Honors Theses
Pathogenic bacteria on environmental surfaces in nursing homes may contribute to the growing burden of healthcare-associated infections (HAIs), particularly as the U.S. population ages and more individuals transition into long-term care. In this study, 70 swab samples were collected from five community shower rooms at a nursing home over three sampling trips. Five common shower surfaces were sampled: the floor drain, shower bench, faucet/valves, shower curtain, and grab bars. Samples were processed in the UTC CIDC microbiology lab and inoculated onto four selective and differential media: Hardy CHROM MRSA agar (for methicillin-resistant Staphylococcus aureus [MRSA] and S. pseudintermedius [SIM]), mannitol …
Bacterial Contamination Of Wheelchairs In A Long-Term Rehabilitation Facility, Storm A. Welch
Bacterial Contamination Of Wheelchairs In A Long-Term Rehabilitation Facility, Storm A. Welch
Honors Theses
The presence of bacterial contamination on wheelchair surfaces in long-term care facilities poses a significant risk to infection control and patient safety. This study aimed to assess the prevalence and diversity of bacterial species, including Staphylococcus aureus (SA), methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis (SE), Pseudomonas spp., and enteric bacteria on five key components of wheelchairs at a local long-term care facility. A total of 320 swabs were collected from wheelchair components, including handles for pushing, armrests, seats, wheel handles, and tires. Samples were analyzed using selective culture media, and bacterial species were identified based on colony morphology. The results …
Role Of Pseudomonas Aeruginosa Exoenzymes S, T, And Y In The Modulation Of Intrinsic Apoptosis In Pulmonary Microvascular Endothelial Cells, Andrea M. Vavrinek
Role Of Pseudomonas Aeruginosa Exoenzymes S, T, And Y In The Modulation Of Intrinsic Apoptosis In Pulmonary Microvascular Endothelial Cells, Andrea M. Vavrinek
Honors Theses
P. aeruginosa is the most common cause of ventilator-associated pneumonia in ICU patients. P. aeruginosa uses a type III secretion system to inject exoenzymes S, T, U, and Y into host cells, exhibiting unique effects. Pulmonary microvascular endothelial cells (PMVECs) are used to evaluate cellular changes caused by exoenzymes. ExoY infection of PMVECs leads to cell rounding but does not lead to cell death, unlike ExoS/T. The current study evaluated the exoenzyme-induced modulation of intrinsic apoptosis in endothelial cells. Strain PAK, producing ExoS, T, and Y, was compared to isogenic strains expressing either S, SY, T, TY, Y, or none …
Bacterial Load In Virtual Reality Headsets, Benjamin Creel
Bacterial Load In Virtual Reality Headsets, Benjamin Creel
Honors Theses
Virtual reality technology is a rapidly growing field of computer science. Virtual reality utilizes headsets which cover the user’s eyes, nose, and forehead. In this study, I analyzed the potential for these headsets to become contaminated with bacteria. The nosepieces and foreheads of two HTC Vive VR headsets of the Department of Computer Science of the University of Mississippi were sampled over the course of a seven-week Immersive Media (CSCI 447) course. Serial dilutions were performed, and samples were plated on various culture media. Following incubation, counts of bacteria were determined. DNA was extracted from bacterial growth on plates from …
The Msaabcr Operon Mutant Staphylococcus Aureus Is Deficient In Persister Cells, Aaliyah D. Cole
The Msaabcr Operon Mutant Staphylococcus Aureus Is Deficient In Persister Cells, Aaliyah D. Cole
Honors Theses
Persister cells comprise a phenotypic variant that shows extreme antibiotic tolerance resulting in chronic infections. While this phenomenon has posed a great threat in public health, mechanism underlying their formation in Staphylococcus aureus remains largely unknown. Increasing evidence of the presence of persister cells in recalcitrant infections underscores the great urgency to unravel the mechanism by which these cells are developed. The Elasri Research group characterized msaABCR operon that plays roles in regulation of virulence, biofilm development and antibiotic resistance. It was hypothesized that the operon also plays a role in persister cell formation. In this study, the persister cell …
Understanding The Patterns Of Distribution And Abundance Of Lyme Disease Carrying Ticks And Their Hosts, Julio Ruiz
Understanding The Patterns Of Distribution And Abundance Of Lyme Disease Carrying Ticks And Their Hosts, Julio Ruiz
Honors Theses
Lyme disease is caused by the bacteria Borrelia burgodorferi and spreads to their hosts by the bites of infected Ixodes scapularis ticks. In the United States, Lyme disease is typically found in the northeast but in recent years the disease has begun to be found further south and west than previously before. Yet, today, little information can be found about the patters of distribution and abundance of ticks and their host. The main goal of this research work was to expand the knowledge of the abundance and distribution of ticks and host. Based on tick collection data obtained from Maikis …
The Effect Of Increased Exposure Of Uvc Light On Human Skin Microbiota, T'Kylia S. Moss
The Effect Of Increased Exposure Of Uvc Light On Human Skin Microbiota, T'Kylia S. Moss
Honors Theses
Many methods have been employed to prevent infections from opportunistic pathogens in immunocompromised individuals. Among these are the use of ultraviolet light (UV). In this study, UVC light, was found to have a deleterious effect on specific skin flora. Organisms tested included Acinetobacter baumanii, Candida albicans, Candida kefyr, Corynebacterium renale, Enterococcus faecalis, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus pyogenes. Nutrient agar was used to cultivate most organisms. Blood agar was used for the cultivation of Streptococcus pyogenes and Enterococcus faecalis. Bacterial suspensions were made and utilized to plate each organism onto a set of 7 nutrient agar or …