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Articles 1 - 9 of 9
Full-Text Articles in Animal Diseases
Anthelmintic Resistance In Sheep Across Ireland And The Uk: A Literature Review Of The In Vivo Versus In Vitro Methods, Megan Tumulty
Anthelmintic Resistance In Sheep Across Ireland And The Uk: A Literature Review Of The In Vivo Versus In Vitro Methods, Megan Tumulty
SURE Journal: Science Undergraduate Research Experience Journal
Background: The animal welfare and production consequences of gastrointestinal nematode infections, namely Nematodirus battus, on sheep are compelling. The control of gastrointestinal infections has been heavily reliant on the administration of anthelmintics since their introduction into mainstream use in 1960. However, their frequent and often excessive use has resulted in anthelmintic resistance being reported extensively in several gastrointestinal nematode species. The prevalence of anthelmintic resistance as well as the increase in the number of cases of multiple-drug resistance in nematode populations now poses substantial hindrance on the viability of sheep production systems. However, despite the threat N. battus poses …
Entomological Assessment Of Tsetse-Borne Trypanosome Risk In The Shimba Hills Human-Wildlife-Livestock Interface, Kenya, Faith I. Ebhodaghe, Armanda D.S. Bastos, Michael N. Okal, Daniel K. Masiga
Entomological Assessment Of Tsetse-Borne Trypanosome Risk In The Shimba Hills Human-Wildlife-Livestock Interface, Kenya, Faith I. Ebhodaghe, Armanda D.S. Bastos, Michael N. Okal, Daniel K. Masiga
All Peer-Reviewed Publications
Shimba Hills is a wildlife area in Kenya and a major focus of tsetse-borne trypanosomes in East Africa. In Shimba Hills, tsetse-borne trypanosomes constrain animal health and smallholder livelihoods. However, epidemiological data to guide hotspot-targeted control of infections are limited. This study assessed the dynamics of tsetse-borne trypanosome risk in Shimba Hills with the objective to describe infection hotspots for targeted control. Tsetse flies (n = 696) collected in field surveys between November 2018 and September 2019 in Shimba Hills were characterized for chronological age and phenotypic sizes and screened for trypanosome and cattle DNA. Entomological inoculation rates for trypanosome …
Histomonosis In Turkeys – Factors Influencing Transmission, Pathogenesis, And The Search For Prophylactic Or Therapeutic Compounds, Thainá Landim De Barros
Histomonosis In Turkeys – Factors Influencing Transmission, Pathogenesis, And The Search For Prophylactic Or Therapeutic Compounds, Thainá Landim De Barros
Graduate Theses and Dissertations
The incidence of histomonosis has been increasing in poultry since the ban of prophylactic and therapeutic compounds. Histomonosis is caused by the protozoa Histomonas meleagridis. The objective of this dissertation was to investigate factors impacting the pathogenesis and transmission of histomonosis and to evaluate compounds that could potentially prevent or reduce the severity of histomonosis in turkeys. In the first study, the effect of sodium chlorate and sodium nitrate on reducing histomonads growth was tested in vitro and added to a basal turkey diet. A decrease in the growth of histomonads in vitro was observed, but no in vivo effect …
Satellite-Based Modelling Of Potential Tsetse (Glossina Pallidipes) Breeding And Foraging Sites Using Teneral And Non-Teneral Fly Occurrence Data, Stella Gachoki, Thomas Groen, Anton Vrieling, Michael Okal, Andrew Skidmore, Daniel Masiga
Satellite-Based Modelling Of Potential Tsetse (Glossina Pallidipes) Breeding And Foraging Sites Using Teneral And Non-Teneral Fly Occurrence Data, Stella Gachoki, Thomas Groen, Anton Vrieling, Michael Okal, Andrew Skidmore, Daniel Masiga
All Peer-Reviewed Publications
Background: African trypanosomiasis, which is mainly transmitted by tsetse flies (Glossina spp.), is a threat to public health and a significant hindrance to animal production. Tools that can reduce tsetse densities and interrupt disease transmission exist, but their large-scale deployment is limited by high implementation costs. This is in part limited by the absence of knowledge of breeding sites and dispersal data, and tools that can predict these in the absence of ground-truthing. Methods: In Kenya, tsetse collections were carried out in 261 randomized points within Shimba Hills National Reserve (SHNR) and villages up to 5 km from the reserve …
Impact Of Disease On The Survival Of Three Commercially Fished Species, John M. Hoenig, Maya L. Groner, Matthew W. Smith, Wolfgang K. Vogelbein, David M. Taylor, Donald F. Landers Jr., John T. Swenarton, David T. Gauthier
Impact Of Disease On The Survival Of Three Commercially Fished Species, John M. Hoenig, Maya L. Groner, Matthew W. Smith, Wolfgang K. Vogelbein, David M. Taylor, Donald F. Landers Jr., John T. Swenarton, David T. Gauthier
Biological Sciences Faculty Publications
Recent increases in emergent infectious diseases have raised concerns about the sustainability of some marine species. The complexity and expense of studying diseases in marine systems often dictate that conservation and management decisions are made without quantitative data on population-level impacts of disease. Mark-recapture is a powerful, underutilized, tool for calculating impacts of disease on population size and structure, even in the absence of etiological information. We applied logistic regression models to mark-recapture data to obtain estimates of disease-associated mortality rates in three commercially important marine species: snow crab (Chionoecetes opilio) in Newfoundland, Canada, that experience sporadic epizootics …
Space-Time Modelling Of Emerging Infectious Diseases: Assessing Leptospirosis Risk In Sri Lanka, Cameron C F Plouffe
Space-Time Modelling Of Emerging Infectious Diseases: Assessing Leptospirosis Risk In Sri Lanka, Cameron C F Plouffe
Theses and Dissertations (Comprehensive)
In this research, models were developed to analyze leptospirosis incidence in Sri Lanka and its relation to rainfall. Before any leptospirosis risk models were developed, rainfall data were evaluated from an agro-ecological monitoring network for producing maps of total monthly rainfall in Sri Lanka. Four spatial interpolation techniques were compared: inverse distance weighting, thin-plate splines, ordinary kriging, and Bayesian kriging. Error metrics were used to validate interpolations against independent data. Satellite data were used to assess the spatial pattern of rainfall. Results indicated that Bayesian kriging and splines performed best in low and high rainfall, respectively. Rainfall maps generated from …
Occurrence Of Rift Valley Fever In Cattle In Ijara District, Kenya, Nelson O. Owange, William O. Ogara, Hippolyte Affognon, Gathura B. Peter, Jacqueline Kasiiti, Sam Okuthe, W. Onyango-Ouma, Tobias Landmann, Rosemary Sang, Murithi Mbabu
Occurrence Of Rift Valley Fever In Cattle In Ijara District, Kenya, Nelson O. Owange, William O. Ogara, Hippolyte Affognon, Gathura B. Peter, Jacqueline Kasiiti, Sam Okuthe, W. Onyango-Ouma, Tobias Landmann, Rosemary Sang, Murithi Mbabu
All Peer-Reviewed Publications
Ijara district in Kenya was one of the hotspots of rift valley fever (RVF) during the 2006/2007 outbreak which led to human and animal deaths causing huge economic and public health losses. The main constraint in the control and prevention of RVF is inadequate knowledge on its occurrence during the interepidemic period. This study was aimed at understanding the occurrence of RVF in cattle in Ijara to enable the development of improved community-based disease surveillance, prediction, control and prevention.Six herds each 700-1000 cattle were identified with participatory involvement of locals and project technical team of the project. One animal per …
Detection Of Trypanosomes In Small Ruminants And Pigs In Western Kenya: Important Reservoirs In The Epidemiology Of Sleeping Sickness?, Musa O. Ng'ayo, Zablon K. Njiru, Eucharia U. Kenya, Geoffrey M. Muluvi, Ellie O. Osir, Daniel K. Masiga
Detection Of Trypanosomes In Small Ruminants And Pigs In Western Kenya: Important Reservoirs In The Epidemiology Of Sleeping Sickness?, Musa O. Ng'ayo, Zablon K. Njiru, Eucharia U. Kenya, Geoffrey M. Muluvi, Ellie O. Osir, Daniel K. Masiga
All Peer-Reviewed Publications
Background: Trypanosomosis is a major impediment to livestock farming in sub-Saharan Africa and limits the full potential of agricultural development in the 36 countries where it is endemic. In man, sleeping sickness is fatal if untreated and causes severe morbidity. This study was undertaken in western Kenya, an area that is endemic for both human and livestock trypanosomosis. While trypanosomosis in livestock is present at high levels of endemicity, sleeping sickness occurs at low levels over long periods, interspersed with epidemics, underscoring the complexity of the disease epidemiology. In this study, we sought to investigate the prevalence of trypanosomes in …
Isolation Of Trypanosoma Spp. From Wild Tsetse Flies Through Procyclic Expansion In Glossina Morsitans Centralis, Steve Mihok, Eli N. Munyoki, Freddie Masaninga, Paul N. Ndegwa, Reardon O. Olubayo
Isolation Of Trypanosoma Spp. From Wild Tsetse Flies Through Procyclic Expansion In Glossina Morsitans Centralis, Steve Mihok, Eli N. Munyoki, Freddie Masaninga, Paul N. Ndegwa, Reardon O. Olubayo
All Peer-Reviewed Publications
Procyclic trypanosomes from wild tsetse flies were membrane-fed to Glossina morsitans centralis in order to develop an optimal technique for propagating field isolates. A 70% success rate was achieved in isolating Trypanosoma simiae and a variety of genotypes of T. congolense originating from G. pallidipes, G. brevipalpis and G. swynnertoni. Parasites matured into forms infective for mammals, and could be maintained by passage of gut forms to new groups of flies. In experiments with laboratory stocks, we also passaged immature gut infections of T. congolense and T. brucei from various tsetse species to G. m. centralis. The optimal technique was …