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Full-Text Articles in Diseases

New Ionis Data Show Positive Trends In Clinical Measures Of Huntington's Disease Drug Trial Volunteers, Kenneth P. Serbin Apr 2018

New Ionis Data Show Positive Trends In Clinical Measures Of Huntington's Disease Drug Trial Volunteers, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Nora Guthrie: We’Re All ‘Hoping Machines’ In The Fight Against Huntington's Disease, Kenneth P. Serbin Apr 2018

Nora Guthrie: We’Re All ‘Hoping Machines’ In The Fight Against Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Roche Gears Up For Pivotal Phase 3 Huntington’S Disease Gene-Slicing Clinical Trial, Kenneth P. Serbin Mar 2018

Roche Gears Up For Pivotal Phase 3 Huntington’S Disease Gene-Slicing Clinical Trial, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


In Chronicling The Quest To Cure Huntington’S Disease, A Whirlwind Of Emotions, Kenneth P. Serbin Mar 2018

In Chronicling The Quest To Cure Huntington’S Disease, A Whirlwind Of Emotions, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


The Best News For The Huntington's Disease Community Since The Discovery Of The Gene: Ionis Trial Data Revealed, Roche Confirms Jump To Phase 3, Kenneth P. Serbin Mar 2018

The Best News For The Huntington's Disease Community Since The Discovery Of The Gene: Ionis Trial Data Revealed, Roche Confirms Jump To Phase 3, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Overflow Audience At 13th Annual Huntington's Disease Therapeutics Conference, Kenneth P. Serbin Feb 2018

Overflow Audience At 13th Annual Huntington's Disease Therapeutics Conference, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Chdi's 13th Conference Promises Some Good News For The Huntington's Disease Community, Kenneth P. Serbin Feb 2018

Chdi's 13th Conference Promises Some Good News For The Huntington's Disease Community, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Faith In Each Other: Sticking Together Through The Challenges Of Huntington's Disease, Kenneth P. Serbin Feb 2018

Faith In Each Other: Sticking Together Through The Challenges Of Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Possible Breakdown Of Dopamine Receptor Synergism In A Mouse Model Of Huntington's Disease, Samantha F. Kennedy Dec 2017

Possible Breakdown Of Dopamine Receptor Synergism In A Mouse Model Of Huntington's Disease, Samantha F. Kennedy

LSU New Orleans Theses and Dissertations

The model of basal ganglia function proposed by Albin, Young and Penney (1989) describes two anatomically independent motor pathways, the direct and indirect. However, under normal conditions striatal dopamine (DA) is required for the expression of motor behavior, and DAergic control of the two pathways (via D1 and D2 receptors, respectively) is dependent on co-activation. We tested for a possible breakdown of D1/D2 synergism using transgenic R6/1 mice bearing the human huntingtin allele (Htt). Motor stereotypy, observed prior to the onset of HD-related symptoms, was rated on a 5-point scale following activation of: A) D1 receptors alone, B) D2 receptors …


Ionis Scientists Provide Initial Assessment Of Successful Phase 1/2a Huntington's Disease Trial And Discuss Next Steps, Kenneth P. Serbin Dec 2017

Ionis Scientists Provide Initial Assessment Of Successful Phase 1/2a Huntington's Disease Trial And Discuss Next Steps, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Ionis Drug Successfully Reduces Toxic Huntington’S Disease Protein, Paving Way For Phase 2 Trial Of Effect On Patients, Kenneth P. Serbin Dec 2017

Ionis Drug Successfully Reduces Toxic Huntington’S Disease Protein, Paving Way For Phase 2 Trial Of Effect On Patients, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


A Time For Hope: Hdsa’S 50th Anniversary, A Record-Setting Gala, And The Impending Release Of Highly Anticipated Clinical Trial Results, Kenneth P. Serbin Nov 2017

A Time For Hope: Hdsa’S 50th Anniversary, A Record-Setting Gala, And The Impending Release Of Highly Anticipated Clinical Trial Results, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Advocacy In The Workplace: Raising Awareness About Huntington's Disease And Brain Health, Kenneth P. Serbin Oct 2017

Advocacy In The Workplace: Raising Awareness About Huntington's Disease And Brain Health, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Ionis Huntington’S Disease Drug A Step Closer To A Critical Phase 2 Study, Kenneth P. Serbin Jun 2017

Ionis Huntington’S Disease Drug A Step Closer To A Critical Phase 2 Study, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Join The Facebook Live Event (Soon!) On Pope Francis's Historic Audience With Huntington's Disease Families, Kenneth P. Serbin May 2017

Join The Facebook Live Event (Soon!) On Pope Francis's Historic Audience With Huntington's Disease Families, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Francis Made A Day Of ‘Superlatives’ For The Huntington's Disease Community, Says Event Co-Organizer, Kenneth P. Serbin May 2017

Francis Made A Day Of ‘Superlatives’ For The Huntington's Disease Community, Says Event Co-Organizer, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Pope Francis Declares: Huntington’S Disease Should Be 'Hidden No More', Kenneth P. Serbin May 2017

Pope Francis Declares: Huntington’S Disease Should Be 'Hidden No More', Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Fear Not, Huntington’S Disease Families – Pope Francis Has Our Backs, Kenneth P. Serbin May 2017

Fear Not, Huntington’S Disease Families – Pope Francis Has Our Backs, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Preparing For The Meeting With Pope Francis, A Heartening Milestone In The Huntington's Disease Movement, Kenneth P. Serbin Apr 2017

Preparing For The Meeting With Pope Francis, A Heartening Milestone In The Huntington's Disease Movement, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Pope Francis I To Meet With Victims Of Huntington’S Disease, A First For A World Leader, Kenneth P. Serbin Mar 2017

Pope Francis I To Meet With Victims Of Huntington’S Disease, A First For A World Leader, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Staying When The Chargers Leave: A Leading Huntington's Disease Advocate Sets A Gutsy, Loving Example, Kenneth P. Serbin Feb 2017

Staying When The Chargers Leave: A Leading Huntington's Disease Advocate Sets A Gutsy, Loving Example, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Banning College Football: An Urgent Objective For Brain Health Advocates, Kenneth P. Serbin Feb 2017

Banning College Football: An Urgent Objective For Brain Health Advocates, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Passing On The Huntington’S Disease Advocacy Baton To The Next Generation, Kenneth P. Serbin Jan 2017

Passing On The Huntington’S Disease Advocacy Baton To The Next Generation, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


This Thanksgiving, Let’S Show Gratitude For Disease Researchers And Drug Hunters, Kenneth P. Serbin Nov 2016

This Thanksgiving, Let’S Show Gratitude For Disease Researchers And Drug Hunters, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


‘Crying A Few Million Tears’ For The Fallen Victims Of Huntington's Disease, Kenneth P. Serbin Nov 2016

‘Crying A Few Million Tears’ For The Fallen Victims Of Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Ionis Phase I Huntington’S Disease Trial At Halfway Mark: 'No Surprises So Far' Means Good News, Kenneth P. Serbin Oct 2016

Ionis Phase I Huntington’S Disease Trial At Halfway Mark: 'No Surprises So Far' Means Good News, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Dreams For A Better Future: An Opportunity We Huntington's Disease People And Our Families Are Denied, Kenneth P. Serbin Sep 2016

Dreams For A Better Future: An Opportunity We Huntington's Disease People And Our Families Are Denied, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Upbeat Huntington’S Disease Film, Featuring Undaunted Family, Aims For 10 Million Views, Kenneth P. Serbin May 2016

Upbeat Huntington’S Disease Film, Featuring Undaunted Family, Aims For 10 Million Views, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


A Family United Against Huntington’S Disease, Kenneth P. Serbin May 2016

A Family United Against Huntington’S Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


From Sheepish To Self-Assured In The Fight Against Huntington's Disease, Kenneth P. Serbin Apr 2016

From Sheepish To Self-Assured In The Fight Against Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.