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Full-Text Articles in Oral Biology and Oral Pathology

Clinicopathologic Study Of Odontogenic Keratocysts In Singapore And Malaysia, Ngeow W. C., Rosnah Binti Zain, Yeo J. F., Chai W. L. May 1999

Clinicopathologic Study Of Odontogenic Keratocysts In Singapore And Malaysia, Ngeow W. C., Rosnah Binti Zain, Yeo J. F., Chai W. L.

Prof. Dr. Rosnah Binti Zain

A retrospective study of odontogenic keratocysts in the Malaysia-Singapore region was done. The purpose of this study is to present the clinicopathological features of odontogenic keratocysts in the Oriental population and to compare the data with those from other reported studies. Biopsy records from 1981 to 1992 of 61 cases of odontogenic keratocysts in Malaysia and Singapore showed that there were 42.6% female and 57.4% male patients. The cysts occurred in 75.4% Chinese, 6.6% Malays, 9.8% Indian, and 8.2% other ethnic groups. The mean age of these patients was 26.98 ± 15.38 years with peak incidence in the second to …


Tenascin-C In Betel-Quid Associated Lesions, Rosnah Binti Zain, Fukano H., Ikeda N., Kudeken W., Shrestha P., Ghazali M. N., Takai Y., Mori M. Apr 1999

Tenascin-C In Betel-Quid Associated Lesions, Rosnah Binti Zain, Fukano H., Ikeda N., Kudeken W., Shrestha P., Ghazali M. N., Takai Y., Mori M.

Prof. Dr. Rosnah Binti Zain

The expression of Tenascin-C, an adhesion modulating or anti- adhesive extracellular matrix protein, was evaluated in betel quid associated lesions of oral mucosa showing focal hyperkeratosis (n=15), dysplasia (n=15), oral submucous fibrosis (n=7) and oral squamous cell carcinoma (n=8). All the patients were chewers of betel quid containing betel leaves, areca nuts, lime and tobacco. The results obtained from this study were compared to similar lesions in smokers and non-quid users cited in the literature (Shrestha et al, Oral Oncol, 1994). An enhanced expression of TN-C was observed in epithelial connective tissue interface of quid associated hyperkeratotic and dyplastic mucosa. …


Pcna Expression In Epithelial Linings Of Odontogenic Cysts And Unicystic Ameloblastoma, Sudiono J., Rosnah Binti Zain Apr 1999

Pcna Expression In Epithelial Linings Of Odontogenic Cysts And Unicystic Ameloblastoma, Sudiono J., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

Proliferating cell nuclear antigen (PCNA) is a nuclear protein synthesized in the late G1 and S phase of the cell cycle. It is a useful marker for the proliferating fraction of cells in tissue specimens. The purpose of this study was to describe the expression of PCNA within epithelial linings of odontogenic cyst and to compare the proliferative activities of these lesion using PCNA labeling indices. A total of 61 cases of odontogenic cysts and unicystic ameloblastomas (18 radicular cysts, 16 dentigerous cysts, 15 odontogenic keratocysts (OKC) an 12 unicystic ameloblastomas) was studied. It was found that PCNA staining were …


An Epidemiological Survey Of Oral Mucosal Lesions Among Elderly Malaysians, Taiyeb Ali T. B., Razak I. A., Raja Latifah R. J., Rosnah Binti Zain Jul 1995

An Epidemiological Survey Of Oral Mucosal Lesions Among Elderly Malaysians, Taiyeb Ali T. B., Razak I. A., Raja Latifah R. J., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

A house to house random survey on elderly subjects was undertaken in the District of Klang in Malaysia. The objective of this study was to investigate the prevalence of oral mucosal lesions (OML) among the elderly in this area. The primary units in the sampling frame were the Enumeration Blocks (EBs) as defined under the population census. All households of the selected EBs were considered as sampling units and members aged 60 and above were considered as respondents. There was a slight preponderance of females, with the Malays comprising the majority of the subjects. Of the 486 respondents, mean aged …


Oral Pyogenic Granuloma (Excluding Pregnancy Tumour)--A Clinical Analysis Of 304 Cases, Rosnah Binti Zain, Khoo S. P., Yeo J. F. Jan 1995

Oral Pyogenic Granuloma (Excluding Pregnancy Tumour)--A Clinical Analysis Of 304 Cases, Rosnah Binti Zain, Khoo S. P., Yeo J. F.

Prof. Dr. Rosnah Binti Zain

A clinical analysis of 304 cases of pyogenic granuloma (excluding pregnancy tumour) were obtained from the clinical evaluations submitted by clinicians while sending specimens for biopsy. The average age of the patients with pyogenic granuloma was 28.9 years with a peak age incidence in the second decade. More female patients were affected and the lesions present mainly in the Chinese. The majority of the lesions were ulcerated and pedunculated. The lesions had a mean diameter of 10.8 mm with a mean lesion duration of 6.0 months. The gingiva was the prevalent site for these lesions with a greater number being …


Fibrous Lesions Of The Gingiva: A Histopathologic Analysis Of 204 Cases, Rosnah Binti Zain, Fei Y. J. Oct 1990

Fibrous Lesions Of The Gingiva: A Histopathologic Analysis Of 204 Cases, Rosnah Binti Zain, Fei Y. J.

Prof. Dr. Rosnah Binti Zain

Two hundred four cases of fibrous lesions of the gingiva were studied histologically for the presence of calcified tissue, the nature of the connective tissue, the type of keratinization, and the degree of epithelial thickness. Initially these lesions were subcategorized into four specific entities, namely fibrous epulis, fibroepithelial polyp, calcifying fibroblastic granuloma, and ossifying fibrous epulis. It was found that 46.5% of the lesions contained calcifications. The connective tissue was represented predominantly by either the collagenous type (50.5%) or the mixed (cellular and collagenous) type (44.6%). It was also found that 36% of the lesions were ulcerated, and, of these, …


Association Between Cigarette-Smoking And Prevalence Of Oral Mucosal Lesions Among Malaysian Army Personnel, Rosnah Binti Zain, Razak I. A. May 1989

Association Between Cigarette-Smoking And Prevalence Of Oral Mucosal Lesions Among Malaysian Army Personnel, Rosnah Binti Zain, Razak I. A.

Prof. Dr. Rosnah Binti Zain

The association between cigarette smoking and the prevalence of oral mucosal lesions was examined in 495 Malaysian army personnel. No associations between cigarette smoking and recurrent aphthous ulcerations, pre-leukoplakia and frictional keratosis could be obtained in this study. Positive associations were found between cigarette smoking and leukoedema as well as denture stomatitis. There was a negative association between cigarette smoking and the presence of coated tongue.


Clinical Presentation Of Buccal Carcinoma. A Review Of Twenty Nine Patients, Janakarajah N., Rosnah Binti Zain Jan 1984

Clinical Presentation Of Buccal Carcinoma. A Review Of Twenty Nine Patients, Janakarajah N., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

29 patients with buccal carcinoma were reviewed for the clinical signs and symptoms. The TNM classification following the UICC categories were used for the clinical staging of the lesion. The patient’s race, age, sex and habits were also noted. Most of these patients presented with advanced lesions. The most common signs and symptoms were pain and ulcerations (62%). The histopathology of a well-differentiated squamous cell carcinoma forms a great majority of these lesions (62%). Each of the sign and symptom is discussed in relation to other findings that had been reported.