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Full-Text Articles in Oral Biology and Oral Pathology

Double Immunohistochemical Analysis Of Pcna And Fak Expression In Selected Odontogenic Lesions, Safaa Baz, Sally Ibrahim Apr 2023

Double Immunohistochemical Analysis Of Pcna And Fak Expression In Selected Odontogenic Lesions, Safaa Baz, Sally Ibrahim

Dentistry

Background: Odontogenic neoplasms and cysts have diverse biological behaviors, ranging from indolence to aggression along a spectrum. The proliferating cell nuclear antigen (PCNA) is an antigen involved in DNA synthesis and proliferation. Focal adhesion kinase (FAK) is a cytoplasmic molecule associated with cellular signaling, growth, and invasion. PCNA and FAK markers have been shown to be involved in neoplastic proliferation, invasion, and migration. Hence, an immunohistochemical assay of PCNA and FAK can be used as a predictive tool for the level of aggressive behavior of odontogenic lesions. Methods: The current study was conducted to evaluate the expressions of PCNA and …


Comorbidity Of Hypertension And Chronic Renal Failure And Their Impact On Oral Complications: A Cross-Sectional Study., Dalia Ghalwash, Sara Abdelwahed, Asmaa Abobakr Jan 2023

Comorbidity Of Hypertension And Chronic Renal Failure And Their Impact On Oral Complications: A Cross-Sectional Study., Dalia Ghalwash, Sara Abdelwahed, Asmaa Abobakr

Dentistry

The present study aimed to investigate the influence of both end-stage renal diseases (ESRD) and hypertension (HTN) on the various oral manifestations and periodontal condition, to evaluate and compare the oral manifestations and periodontal health status in hypertensive patients with ESRD versus control, and to explore any possible correlation of the oral findings with systemic disease status. This was a cross-sectional study which included two equal groups of patients, Group I were hypertensive patients with ESRD and Group II were hypertensive patients only. All patients were hypertensive and were on antihypertensive medications. Regarding the incidence of oral lesions in both …