Oral Biology and Oral Pathology Commons^™

Odontogenic Myxoma In Maxilla: A Case Report, Deepak Gupta, Ravinder Singh, Nazrana Maqbool B.D.S., Rakashree Chakraborty B.D.S., M.D.S.

The New York State Dental Journal

Odontogenic myxoma (OM) is a rare, benign but locally invasive intraosseous neoplasm. It is known to arise from the mesenchymal portion of the tooth germ. Although it is a slow-growing tumor, maxillary odontogenic myxomas can lead to increased morbidity caused by invasion into the maxillary sinus and middle cranial fossa. Further, it is also important to delineate the margins of OM to achieve a better treatment outcome. Here we present a case of a maxillary odontogenic myxoma in a 26-year-old female patient. The patient presented with swelling on the upper right side of the face. Computed tomography scan revealed a …

Diagnostic Challenge: Oral Pathology

Journal IDA

The challenge: We present a case of a 27-year-old female patient who presented to the Fritts Screening Clinic at Indiana University School of Dentistry. She takes metformin for pre-diabetes and levothyroxine for hypothyroidism. Her extraoral exam reveals no pathologies. The intraoral clinical examination reveals a non-wipeable unifocal hyperkeratotic papillary lesion measuring 0.8 x 0.5 cm on the left lateral border of the tongue (Figure 1). The patient reports noticing it approximately a month before the screening appointment; however, she did not experience any pain or other symptoms in the area. An excisional biopsy is performed to obtain a definite diagnosis …

Pebbly Gingival Nodule In An Older Male, Victoria L. Scarpa D.D.S., M.S., Yussra O. Mahmud M.P.H., B.S., Daria Vasilyeva D.D.S., Ph.D.

The New York State Dental Journal

We herein present a case of a giant cell fibroma in an older adult male that clinically has a pebbly or bosselated surface architecture, mimicking a squamous papilloma. The giant cell fibroma is a fibrous tumor distinct from the common irritation fibroma and may easily be mistaken for a papilloma based on clinical features. This case is reported to provide diagnostic value to the general practitioner.

Titanium Hypersensitivity As Possible Cause Of Dental Implant Failures, William J. Maloney D.D.S., Pg Certmeded, Facd, George Raymond D.D.S., Facd, Maura Maloney D.D.S.

The New York State Dental Journal

For many decades, titanium implants have achieved a remarkably high success rate. However, there are cases in which osseointegration does not occur as predicted or desired. In these cases, an analysis of the factors that led to the implant failure must be conducted. There are multiple, widely accepted potential causes of such implant failures. Today, one must also consider titanium hypersensitivity as a potential reason for failure. Symptoms of a titanium allergic reaction may include mucosal erythema, swelling of lips, purpuric patches on hard and soft palate, ulcers in the oral cavity, hyperplastic gingivitis, cheilitis, eczematous eruptions on face and …

Amyloidoma Of The Palate, Philip Bacigalupo D.D.S., Nora Odingo B.D.S., D.M.D., M.P.H.

The New York State Dental Journal

There have been 17 reported cases of isolated amyloid deposition (amyloidoma) of the hard palate (Table 1). We present an 18th case, with a review of the literature on amyloidosis. Systemic conditions, such as multiple myeloma, must be ruled out when amyloid deposition is present. However, localized amyloidoma of the palate is rare, and there are few cases reported in the literature.

Oral Myeloid Sarcoma: Rare Presentation Of Refractory Acute Myeloid Leukemia With Adverse Molecular Profile, Lauren A. Musial, Naomi Ramer Dds

The New York State Dental Journal

Myeloid sarcoma is a rare extramedullary presentation of acute myeloid leukemia and is especially uncommon in the oral cavity. The presence of myeloid sarcoma may be the initial manifestation of an underlying hematolymphoid disorder or may indicate relapsing disease. We report a case of a 48-year-old male with refractory acute myeloid leukemia who presented with a painful, yellow, plaque-like ulceration on the buccal mucosa. Incisional biopsy demonstrated ulcerated squamous mucosa with a dense infiltrate of large, atypical immunoblastic cells admixed with a prominent population of morphologically atypical eosinophils. These findings were consistent with myeloid sarcoma in the context of the …

N Y State Dent J June 2026

The New York State Dental Journal

In the June/July 2026 issue, the reader will find the following feature articles:

• HIV Screenings in Dental Settings: Feasibility, Challenges and Opportunities
• Oral Myeloid Sarcoma
• Generational Differences in Dentistry and Dental Practice

This issue includes regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Oral And Maxillofacial Pathology Case Of The Month, John E. Kacher Dds

The Journal of the Michigan Dental Association

This case concerns a 39-year-old female patient presenting with an asymptomatic radiolucency and spiking root resorption in the right posterior mandible (tooth #30). The patient delayed treatment for three years due to the COVID-19 pandemic and fear of surgery. Upon return, the lesion had greatly expanded in size (approximately 22-by-17 mm), with increased root resorption. Surgery involved extraction of the tooth and thorough curettage of the lesion. Microscopic examination showed cellular tumor composed of plump spindle cells and interspersed psammoma body calcifications. The final diagnosis was aggressive ossifying fibroma, psammomatoid variant. Treatment typically involves complete local excision and curettage …

J Mich Dent Assoc October 2025

The Journal of the Michigan Dental Association

Each month, the Journal of the Michigan Dental Association delivers news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. It remains the main publication reaching Michigan dentists and is available worldwide through ADACommons. The October 2025 (Volume 107, No. 10) issue of the Journal is published in a digital-only format to provide updates and insights for Michigan's oral health community and MDA members. Print editions will resume in November. The October issue highlights the critical importance of advocacy through the MDA Dental Political Action Committee (PAC) and provides practical, management-focused information …

N Y State Dent J August-September 2025

The New York State Dental Journal

In the August-September 2025 issue, the reader will find the following feature articles:

• "Subcutaneous Facial Emphysema and Pneumomediastinum Following a Class V Dental Restoration"
• "Beyond Brushing: Can Toothpaste Cure Your Child’s Peanut Allergy?"
• "Gorlin-Goltz Syndrome with Familial Manifestation: A Case Report with Emphasis on Early Diagnosis"

This issue includes regular columns with regional news impacting the New York membership including: editorial and legal columns, association activities, component news, continuing education opportunities, and classifieds.

Beyond Brushing: Can Toothpaste Cure Your Child’S Peanut Allergy?, Michael J. Heiss D.D.S., Benjamin Solomowitz Dmd

The New York State Dental Journal

Peanut allergies pose significant health risks globally, with an increasing prevalence observed over the past two decades. Accidental exposures to peanuts can lead to severe allergic reactions, including anaphylaxis, prompting the exploration of innovative therapeutic approaches to mitigate these risks. This literature review examines the potential use of peanut proteins embedded within toothpaste formulations as a novel avenue for inducing tolerance in individuals with peanut allergies. It includes recent studies and clinical trials in oral immunotherapy, focusing on mechanisms of action, safety profiles and long-term outcomes associated with controlled allergen exposure. Key findings suggest that oral mucosal therapy, particularly sublingual …

Gorlin-Goltz Syndrome With Familial Manifestation: A Case Report With Emphasis On Early Diagnosis, Ravinder Singh, Deepak Gupta, Aashna Garg, Aanchal Gupta, Sushruh Nayak

The New York State Dental Journal

Gorlin-Goltz syndrome is a hereditary autosomal dominant disorder. It has multiple clinical manifestations caused by mutation in the patched gene (PTCH), which is responsible for the growth and development of healthy tissue and for regulating the cell cycle. Early diagnosis of the condition and an extended duration of follow-up are essential to prevent complications, such as basal cell carcinomas and facial deformities, leading to a more favorable prognosis. This case was diagnosed with the presence of three major and two minor criteria, which confirmed the condition. We hereby report a case of a young male patient diagnosed by clinical, radiological …

Orofacial Manifestations Of Highly Active Antiretroviral Therapy (Haart) And Pre-Exposure Prophylaxis (Prep): Implications For Dental Care And Guidelines For Management, Alec Donelian, Yuedi Yu, Ezzard Rolle Dds, Alison Newgard Dds

The New York State Dental Journal

HAART and PrEP have demonstrated reduction of HIV-related mortality and HIV infection, respectively. A range of orofacial side effects has been associated with both HAART and PrEP. As PrEP usage has increased, there has also been an increase in sexually transmitted infections that have orofacial symptoms. As oral health-care providers, it is important that we recognize these orofacial side effects and symptoms. Further, we offer clinical recommendations for dental professionals treating patients who are on either HAART or PrEP and their associated risk factors.

Pathological Changes In Soft Tissues Associated With Radiographically Normal Impacted Teeth: A Critical Update And Meta-Analysis, Adesh S. Manchanda M.D.S., Ramandeep S. Narang M.D.S., Komaldeep Kaur Sandhu B.D.S

The New York State Dental Journal

The purpose of the study was to conduct a retrospective analysis of histopathological diagnosis of all pericoronal tissues associated with impacted teeth and to correlate it with a hypothetical classification of pericoronal follicular space to improve our clinical management of treating impacted teeth. Materials and Method. The study was carried out in the Department of Oral and Maxillofacial Pathology at Sri Guru Ram Das Institute of Dental Sciences, Amritsar. Data revealed that during a 12-year period, 1,268 patients reported with a pericoronal follicular space associated with the crown of an unerupted tooth, which was subsequently submitted for histopathological evaluation. Panoramic …

Water Fluoridation: The Evidence Behind The Risk Of Fluoride Use, Margherita Fontana D.D.S., Ph.D., Carlos González-Cabezas D.D.S., M.S.D., Ph.D., Livia Tenuta D.D.S., M.Sc., Ph.D.

The Journal of the Michigan Dental Association

The debate surrounding fluoride use for caries control has intensified due to recent events, including a National Toxicology Program (NTP) report and a court ruling mandating EPA action on fluoride levels in tap water.

Despite concerns about fluoride's potential neurodevelopmental impact at high concentrations, current evidence shows no adverse effects at the recommended levels of 0.7 ppm in U.S. community water fluoridation programs. While studies in regions with endemic fluorosis suggest an association between high fluoride exposure and lower IQ, methodological limitations undermine causal conclusions.

Global and U.S. health authorities, including the WHO and ADA, reaffirm the safety and efficacy …

Exophytic And Focally Ulcerated Mass On The Mandibular Gingiva, Abrar Shamim D.D.S., M.A., Scott Peters D.D.S., Shahid R. Aziz D.M.D., M.D., Facs, Frcsed, Gregg Jacob D.M.D., Facs

The New York State Dental Journal

The pyogenic granuloma is a benign vascular proliferation which may present either on the skin or intraorally. While the majority of oral pyogenic granulomas remain less than 1 cm in size, they can grow to large sizes if care is neglected. Herein, we report case of a large pyogenic granuloma on the mandibular alveolar ridge gingiva which grew to 10x10cm in size due to failure to seek treatment.

N Y State Dent J November 2024

The New York State Dental Journal

In the November 2024 issue, the reader will find the following feature articles:

• NYS Workers' Compensation & No-Fault Cases: The Good, the Bad, and the Ugly
• Social Media Use by Dental Students in Dental Education
• Guidelines for Interproximal Enamel Reduction (IPR)
• Exophytic and Focally Ulcerated Mass on the Mandibular Gingiva

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Oral Manifestations Of The Dengue Virus, Griffin S. Eisele, Roman E. Brown Bs, Kristi Soileau Dds, Med, Mshce, Facd, Ficd

New Orleans Dental Association News

Dengue Fever, caused by the DENV virus, is a growing health concern, especially in arid regions. The disease presents oral symptoms that dentists must recognize for timely diagnosis. Dental professionals should exercise caution during surgical procedures due to potential hemorrhagic complications. Early identification and management of oral manifestations can prevent severe outcomes.

Rime: A New Spin On A More Familiar Infection, Ilana Bresky, Kristi Soileau Dds, Med, Mshce, Facd, Ficd

New Orleans Dental Association News

Dental professionals should become familiarized with Reactive Infectious Mucocutaneous Eruption, or RIME, which presents with erosive mucositis typically affecting two or more mucous membranes, frequently in the oral cavity, and oftentimes is accompanied by skin lesions or rash.

‘RIME’ is a relatively new term that was initially designated strictly to the category of MIRM (Mycoplasma-induced rash and mucositis). In 2018, however, the term RIME was adopted to distinguish patients whose mucocutaneous eruption arose from other various respiratory-related illnesses.

Through The Looking Glass, Sarah Glass Dds

Virginia Dental Journal

This article offers a sampling of the fantastical world of oral pathology It includes example images and discusses osseous choristoma, squamous cell carcinoma, traumatic ulcerative granuloma with stromal eosinophilia (TUGSE).

Va Dent J January, February & March 2023

Virginia Dental Journal

In the January, February and March 2023 issue, the reader will find the following feature articles:

• An Interview with Dr. Richard Roadcap: Virginia Dental Journal Editor (2007 – 2023)
• Through the Looking Glass: The Fantastical World of Oral Pathology
• Treatment Access and Outcomes for Craniofacial Care: Patient and Parent Perspectives
• Cheiloscopy
• We’re Taking on the Fight tor Fairness and Transparency: We Need More Dentists to Join the Fight
• Serving the Petersburg Community: VDA Foundation Collaboration with Central Virginia Health Services

This issue includes regular columns with regional news impacting the Virginia membership including: editorial and perspectives columns, legal, association activities, …

An Unusual Presentation Of Langerhans Cell Histiocytosis: Case Report And Review Of The Literature, Aaron E. Yancoskie, Ghazeleh Peiravani Dds, Jordana S. Rothernberg Dds, Anthony S. Alessi Dmd, Md, Heather Z. Fugazy Dds

The New York State Dental Journal

Langerhans cell histiocytosis (LCH) is a destructive process that may involve both hard and soft tissues. While rare, it has a predilection for the oral and maxillofacial region. LCH occurs across the age range, yet is often diagnosed in the pediatric population. The dentigerous cyst (DC) is the most common developmental odontogenic cyst. It typically presents in young adult patients as a solitary lesion associated with impacted third molars. Here we present a case of LCH occurring in the wall of a DC in a 12-year-old male.

Proliferative Verrucous Leukoplakia Progressing To Squamous Cell Carcinoma: A Case Report, Magdalena Orlowska Dds, Felipe Nör Dds, Ms, Phd, Robert Eber Dds, Ms, Stephanie Munz Dds, David Tindle Dds, Ms

The Journal of the Michigan Dental Association

Proliferative verrucous leukoplakia (PVL) is an uncommon type of oral leukoplakia characterized by white patches featuring verrucoid areas. It is a condition of idiopathic origin, displaying a strong tendency to transform into squamous cell carcinoma, verrucous carcinoma, or the newly described particulate carcinoma. PVL is more commonly found in elderly women who have had leukoplakic lesions for many years. Although PVL may be found virtually anywhere in the oral cavity, the buccal mucosa, gingiva, and tongue are the most common sites. In this case, we describe a lesion of this nature found in an elderly male patient. PVL is difficult …

Peripheral Ameloblastoma: Case Report And Literature Review, Anna Cappell Cooper Ba, Daria Vasilyeva Dds, Khanh Trinh Dmd, Elizabeth Philipone Dmd

The New York State Dental Journal

Peripheral ameloblastoma is a benign, painless, and slow-growing odontogenic tumor, which commonly affects gingival soft tissues or edentulous alveolar areas. Peripheral ameloblastoma is typically found during the 5th to 7th decades of life, with a mean patient age of 52 years, and exhibits a male predilection. Histopathology features are consistent with those of conventional ameloblastoma. The treatment of choice is conservative surgical excision with minimal disease-free margins and appropriate follow-up.

Sulfamethoxazole-Trimethoprim Induced Thrombocytopenia: A Report Of Two Cases And A Literature Review, Leigh Griffin Dds, Michael Graffeo Dds, Jay Sher Dds, Paul D. Freedman Dds, Renée F. Reich

The New York State Dental Journal

Sulfamethoxazole- trimethoprim (ST) is a sulfonamide derivative antibiotic that interferes with bacterial folic acid synthesis and growth by blocking dihydrofolic acid formation from para-aminobenzoic acid. One of the potential side effects of sulfamethoxazole-trimethoprim is thrombocytopenia. Thrombocytopenia is a blood disorder characterized by a decreased number of circulating platelets. We present two cases of ST induced thrombocytopenia where the oral manifestations were the first indication of the low platelet count leading to life saving interventions. Our aim is to educate dentists about the oral manifestations of thrombocytopenia and its association with ST as their examination may be instrumental in directing treatment.

Squamous Odontogenic Tumor: A Case Report, Sara Endo Dds, Timothy Chang Dds, Daria Vasilyeva Dds, Scott M. Peters Dds

The New York State Dental Journal

Squamous odontogenic tumors (SOT) are slow-growing, benign, rare intraosseous neoplasms. SOT are typically found in the premolar-canine region of the maxilla and the molar region of the mandible. These lesions have no gender predilection and show peak occurrence in the third decade of life.

Oral Manifestations Of Metastatic Diseases: A Clinical And Histologic Analysis Of 7 Cases, Zeming Zheng Dds, Elizabeth Philipone Dmd

The New York State Dental Journal

Metastatic diseases comprise 1-3% of malignant oral neoplasms with nearly one-third of patients being unaware of having a primary cancer1-4,9. This retrospective analysis identified all oral lesions diagnosed as metastatic disease in the CDM Department of Oral Pathology’s oral biopsy database from 2015-2020 and reported on patient demographics, clinical presentation and diagnosis, origin of the primary, and whether the patient had known history of the disease. From 17,500 total cases, 7 cases were identified as metastatic disease and described in detail. Clinicians’ recognition and awareness of these lesions’ often evasive, ambiguous oral presentations may help facilitate diagnosis, treatment, and prognosis.

N Y State Dent J November 2023

The New York State Dental Journal

In the November 2023 issue, the reader will find the following feature articles:

• Verruciform Xanthoma
• Use of a 3D Intraoral Scanner for Prosthetic Rehabilitation of Cocaine-Induced Oronasal Fistula
• Adenoid Ameloblastoma with Dentinoid

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Verruciform Xanthoma, Khanh Trinh Dmd, Daniel Nassimi Dds, Daria Vaislyeva Dds, Scott Peters Dds

The New York State Dental Journal

Verruciform xanthoma (VX) is a benign epithelial proliferation typically found on the masticatory mucosa. VX usually affects patients in their 5 th to 6 th decade of life. VX is treated with simple excision with a low chance of recurrence after surgery.

Adenoid Ameloblastoma With Dentinoid, Eric Silver Dmd, Md, Stephen Roth Dds, Lydia Lam Dds, John Fantasia Dds, Steve Yusupov Dds, Md

The New York State Dental Journal

Adenoid ameloblastoma with dentinoid (AAD) is a rare benign neoplasm of odontogenic epithelium, with under 50 cases having been reported in the literature. AAD shares histopathological characteristics with both ameloblastomas and adenomatoid odontogenic tumors. They are unique because of dentinoid deposition without enamel. We present a case of AAD in the maxilla of a 13 year old. The patient was treated with left infrastructure maxillectomy and left partial infratemporal fossa dissection. This case reports on an extremely rare disease process in an uncommon location in a pediatric patient.