Bioethics and Medical Ethics Commons^™

Cross-Sector Review Of Drivers And Available 3rs Approaches For Acute Systemic Toxicity Testing, Troy Seidle, Sally Robinson, Tom Holmes, Stuart Creton, Pilar Prieto, Julia Scheel, Magda Chlebus

Experimentation Collection

Acute systemic toxicity studies are carried out in many sectors in which synthetic chemicals are manufactured or used and are among the most criticized of all toxicology tests on both scientific and ethical grounds. A review of the drivers for acute toxicity testing within the pharmaceutical industry led to a paradigm shift whereby in vivo acute toxicity data are no longer routinely required in advance of human clinical trials. Based on this experience, the following review was undertaken to identify (1) regulatory and scientific drivers for acute toxicity testing in other industrial sectors, (2) activities aimed at replacing, reducing, or …

Personal Reflections On Russell And Burch, Frame, And The Hsus, Martin Stephens

Animal Welfare Collection

The coincidence of anniversaries associated with the publication of William Russell and Rex Burch’s The Principles of Humane Experimental Technique, the founding of the Fund for the Replacement of Animals in Medical Experiments (FRAME), and the establishment of the collaboration between FRAME and the University of Nottingham, provides an opportunity to reflect on Russell and Burch’s legacy and how it was carried forward by FRAME. The Principles, published in 1959, was the pioneering work in what later became the alternatives or Three Rs field of replacement, reduction, and refinement of animal use. Such was the book’s initial and undeserved obscurity, …

Exploiting A Research Underclass In Phase 1 Clinical Trials, Carl Elliott, Roberto Abadie

Department of Sociology: Faculty Publications

In November 1996, the Wall Street Journal reported that Eli Lilly was paying homeless alcoholics from a local shelter to participate in safety testing of new drugs at its trial site in Indianapolis.1 “These individuals want to help society,” asserted Lilly’s director of clinical pharmacology. The subjects, however, said they took part for easy money and free room and board. Although Lilly reportedly offered the lowest per diem in the business, it managed to attract poor subjects from all over the country.1 The medical director of the local Homeless Initiative Program said Lilly had created a “shadow economy” of paid …

To The Bitter End: Disparities In End-Of-Life Care, Alberto Coustasse, Theresa Quiroz, Sue G. Lurie

Management Faculty Research

Although technological advancements have provided the means to sustain life and provide care regardless of whether the treatment is appropriate and compassionate given the condition of the patient, bioethical, legal, and moral concerns related to disparities in care still arise in the United States. These concerns call into question the necessity to continue life-sustaining or palliative care treatments when patients and/or families are faced with end-of-life decisions. This study will focus on various historical, clinical cultural, and ethical issues that have placed this dilemma into a controversial public spectrum, by using case studies retrieved from referenced literature, which illustrate disparities …

The Experience Of A Lifestyle, Brian Lonsway

School of Architecture - All Scholarship

This essay traces the evolution of themed environment design from theme parks to a series of new architectural types – Urban Entertainment Destinations, Lifestyle Enhancement Centers, and Lifestyle Villages – as a chronicle of spatial mediation from urban décor to urban design technique. Culled partly through semiotic deconstruction and partly through ethnographic investigation, this history examines the environmental design techniques employed in these spaces in order to better understand the relationship of design practice to the cultural practices of work and leisure.

From spatialized branding strategies to the neo-urbanist configurations of location-based entertainment, leisure/entertainment ventures use these narratively motivated techniques …

Book Review: Social Justice: The Moral Foundations Of Public Health And Health Policy, Robin West

Georgetown Law Faculty Publications and Other Works

This essay is a review of Social Justice: The Moral Foundations of Public Health and Health Policy by Madison Powers & Ruth Faden (2006).

In this pathbreaking book, senior bioethicists Powers and Faden confront foundational issues about health and justice. How much inequality in health can a just society tolerate? In a world filled with inequalities in health and well-being, which inequalities matter most and are the most morally urgent to address? In order to answer these questions, Powers and Faden develop a unique theory of social justice that, while developed for the specific contexts of public health and health …

Update - June 2005, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Universal Access to Health Care and Religious Basis of Human Rights

Update - March 2005, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Review and Critique of Statements on Abuse and Family Violence
-- Seventh-day Adventist Statements on Women's Issues
-- Response to "A Statement on Women's Issues"
-- Seventh-day Adventist Statements on Abuse, A Statement on Abuse and Family Violence
-- Seventh-day Adventist Statements on Abuse, A Statement on Family Violence
-- Seventh-day Adventist Statements on Abuse, Statements on Child Sexual Abuse
-- Editorial

Update - September 2004, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- A Statement on Racism
-- Editorial
-- Review and Critique of "A Statement on Racism"
-- Homelessness and Poverty
-- Review and Critique of the Seventh-day Adventist Policy Statement Titled "Homelessness and Poverty"
-- News from the Center for Christian Biothics
-- Operating Principles for Health-Care Institutions

Animals And Alternatives: Societal Expectations And Scientific Need, Alan M. Goldberg

Experimentation Collection

As Russell and Burch suggested more than 40 years ago, the most humane science is the best science. The path ahead is clear: pain and distress must be eliminated in animal experiments or reduced to an absolute minimum, and, as scientists, we must use the most humane approaches in our research. To accomplish the best science, we must train those who come after us in the principles and practice of humane science.

Killing For The State: The Darkest Side Of American Nursing, Dave Holmes, Cary H. Federman

Department of Justice Studies Faculty Scholarship and Creative Works

The aim of this article is to bring to the attention of the international nursing community the discrepancy between a pervasive ‘caring’ nursing discourse and the most unethical nursing practice in the United States. In this article, we present a duality: the conflict in American prisons between nursing ethics and the killing machinery. The US penal system is a setting in which trained healthcare personnel practices the extermination of life. We look upon the sanitization of death work as an application of healthcare professionals’ skills and knowledge and their appropriation by the state to serve its ends. A review of …

Update - September 2002, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Just Put Me to Sleep . . . PLEASE!: Ethical Issues in Palliative and "Terminal" Sedation
-- Terminal Sedation: A Jewish Perspective
-- Terminal Sedation: A Catholic Perspective
-- Announcing the Center for Christian Bioethics Nation Conference in 2003: "Promise and Peril of the New Genetics"
-- Center news . . .

Update - May 2002, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- The Compleat Physician
-- Informed Consent Documentation for Total Artificial Hearth Technology
-- Ralph J. and Carolyn Thompson Endowment established in 2001

Update - November 2001, Loma Linda University Center For Christian Bioethics

Update

In this issue:

[ Too Risky for Research? ]
-- Human Research with Vulnerable Humans
-- Why Did Jesus Die?

-- Earn a Master's degree from Loma Linda University
-- Center for Christian Bioethics News & Events

An Analysis Of The Changing Forces Behind Health Insurance Coverage Of Homebirth, Christina Anne Gasbarro

Dissertations and Theses

The expansion of managed care, which is premised on containing costs while maintaining market share, represents a radical transformation of the U.S. health care system. A central question for medical sociologists is to determine how the changes brought by managed care influence health insurance and health care options. In evaluating the impacts of managed care, obstetrics is a particularly important site of study. Part of this agenda involves gathering baseline data on a specific transformation in obstetrics practice new to the managed care scene: the emergence of health insurance coverage for the option of home birth. The research project detailed …

The First Forty Years Of The Alternatives Approach: Refining, Reducing, And Replacing The Use Of Laboratory Animals, Martin L. Stephens, Alan M. Goldberg, Andrew N. Rowan

State of the Animals 2001

The concept of the Three Rs— reduction, refinement, and replacement of animal use in biomedical experimentation—stems from a project launched in 1954 by a British organization, the Universities Federation for Animal Welfare (UFAW). UFAW commissioned William Russell and Rex Burch to analyze the status of humane experimental techniques involving animals. In 1959 these scientists published a book that set out the principles of the Three Rs, which came to be known as alternative methods. Initially, Russell and Burch’s book was largely ignored, but their ideas were gradually picked up by the animal protection community in the 1960s and early ’70s. …

Update - November 2000, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- An Unlikely Reverence: The story of Centura Health, a partnership between Seventh-day Adventist and Roman Catholics
-- Child Prostitution in Thailand: Epidemic and Ethics

Medical Students And Their Attitudes Toward Abortion: An Assessment Of Which Factors Influence Medical Students' Willingness Or Unwillingness To Perform Abortions, Katherine M. Krupa

Sociology & Criminal Justice Theses & Dissertations

The purpose of this research is to determine which factors, if any, influence medical students' willingness or unwillingness to perform abortions. Ample research has been conducted evaluating both the general population's and college students' attitudes toward abortion; however, limited research has been collected on medical students. The present research study attempts to fill this void. The following research questions will be reviewed and evaluated throughout the current study: (1) What personal factors if any influence medical students' willingness or unwillingness to terminate a pregnancy; (2) Are medical students willing to perform abortions for the reasons that women are requesting them; …

Medicaid Fraud: Medical Students' And Physicians' Attitudes And Perceptions, Kristin M. Byars

Sociology & Criminal Justice Theses & Dissertations

The purpose of this study is to determine the attitudes and perceptions of medical students and physicians concerning Medicaid fraud. The primary tool was an anonymous survey distributed to both medical students and physicians in the Hampton Roads area. Previous research suggests that physicians would be more likely to view Medicaid fraud as less serious and less justifiable than medical students would. Since little research looks specifically at the attitudes and perceptions of medical students and physicians two theories, Differential Association and the Theory of Organizational Misconduct, were used because they best fit the research already out there. The analyses …

Update - July 1997, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Practicing on Newly Dead Bodies
-- Life versus Death: The Ethical Imperative to Practice and Teach Using the Newly Dead
-- You Can't Always Get What You Want
-- MA in Clinical Ethics
-- MA in Clinical Ministry

Ethnic Minorities And Mental Health: Ethical Concerns In Counseling Immigrants And Culturally-Diverse Groups, Gemima M. Remy

Trotter Review

Between 1980 and 1990 nearly 9 million foreign-born individuals migrated to the United States. In 1993, the Immigration and Naturalization Service recorded the entry of over 900,000 immigrants and refugees. This figure is believed to be higher given the estimated 1.5 to 2.5 million people who enter this country illegally each year. Currently, ethnic minority groups make up one-fourth of the United States population. It is estimated that by the year 2000, one-third of the U.S. population will be comprised of ethnic minorities. As the population of the United States becomes increasingly diverse, considerable attention is being directed to a …

Update - March 1995, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Cabbages and Condoms: Population Control in a Crowded World
-- On Conundrums, Condoms and Cabbages: "Prior Questions" on the Subject of Population Control
-- LLU offers Masters of Arts in Biomedical and Clinical Ethics

The Three Rs: The Way Forward, Michael Balls, Alan M. Goldberg, Julia H. Fentem, Caren L. Broadhead, Rex L. Burch, Michael F.W. Festing, John M. Frazier, Coenraad F.M. Hendriksen, Margaret Jennings, Margot D.O. Van Der Kamp, David B. Morton, Andrew N. Rowan, Claire Russell, William M.S. Russell, Horst Spielmann, Martin Stephens, William S. Stokes, Donald W. Straughan, James D. Yager, Joanne Zurlo, Bert F.M. Van Zutphen

Experimentation Collection

This is the report of the eleventh of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM), which was established in 1991 by the European Commission. ECVAM's main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures which would enable it to become well-informed about the state-of-the-art of non-animal test …

Update - June 1993, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Gerald Winslow to succeed Wil Alexander as Religion Dean and Ethics Chair; Ivan Blazen to teach scripture and ethics
-- Quality-of-Life Is Not a Dirty Word

[ How Secret Should a Patient's Secrets Be? ]
-- Duties to Warn and Reasons for Reticence
-- A Legal Perspective

Update - Special Report November 1992, Loma Linda University Center For Christian Bioethics

Update

In this issue:

[ Special Report to Our Contributors Proposition 161 - Death with Dignity Act, Should It Become Law? ]
-- Yes
-- No

Update - September 1992, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Euthanasia in the Netherlands - Excepts from an interview with Rob Willem Treep

[ Kevorkian and Assisted Suicide ]
-- Thoughts Provoked by Dr. Kevorkian's Suicide Machine
-- Because Laws Against Euthanasia Send a Broader Signal, Experiments Must be Careful
-- Act of Murder or Active Compassion?

Update - May 1992, Loma Linda University Center For Christian Bioethics

Update

In this issue:

[ Faith, Medicine, and Religious Liberty - Part 2, Christian Science ]
-- Spiritual Healing for Children
-- Religious Liberty, Spiritual Healing, and the Health Care of Children
-- Spiritual Healing, Laws, and Constitutional Free Exercise of Religious Rights
-- Baby Theresa: Parental Choice Must Reign in the Case of Brain-Absent Newborns
-- Anencephalic Infants as Organ Donors: Do We Follow Rules or Emotions?

Update - December 1991, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- The Physician as an Agent of God: An Idea Whose Time Has Come

-- [ Medical Futility: A Value-Dependent Concept ]

Update - December 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- The euthanasia debate in the Netherlands: Biolegal, bioethical and biotheological considerations

[ In Vito Fertilization and Divorce ]
-- What Can We Learn?
-- A Legal Perspective
-- Some Thoughts Regarding Frozen Embryos and Devorce

Update - October 1990, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Richard Lamm highlights Ethics and Aging Project
-- A Personal View

[ The Nazi Doctors ]
-- Where Did They Go Wrong?
-- The Slippery Slide of Medical Ethics
-- From Health to Holocaust: Adventists and the Nazi Doctors

-- LLU's Ethics Center supports campaign against international tobacco trade