Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Animals (1)
- Bisexuality (1)
- Cd4 lymphocyte count (1)
- Cd4+ t-lymphocyte count (1)
- Cell differentiation (1)
-
- Cell line (1)
- Cell surface (1)
- Cohort studies (1)
- Condylomata acuminata (1)
- Core binding factor alpha 1 subunit (1)
- Cytology (1)
- Dominant (1)
- Genes (1)
- Genetic (1)
- Genetics (1)
- Genital warts (1)
- Hedgehog proteins (1)
- Hiv (1)
- Hiv infections (1)
- Homosexuality (1)
- Human papillomavirus (hpv) (1)
- Longitudinal/cohort (1)
- Men who have sex with men (msm) (1)
- Metabolism (1)
- Mice (1)
- Multivariate analysis (1)
- Osteoblasts (1)
- Paracrine communication (1)
Articles 1 - 2 of 2
Full-Text Articles in Urogenital System
Smoking Enhances Risk For New External Genital Warts In Men, Dorothy J. Wiley, David Elashoff, Emmanuel V. Masongsong, Diane M. Harper
Smoking Enhances Risk For New External Genital Warts In Men, Dorothy J. Wiley, David Elashoff, Emmanuel V. Masongsong, Diane M. Harper
Dartmouth Scholarship
Repeat episodes of HPV-related external genital warts reflect recurring or new infections. No study before has been sufficiently powered to delineate how tobacco use, prior history of EGWs and HIV infection affect the risk for new EGWs. Behavioral, laboratory and examination data for 2,835 Multicenter AIDS Cohort Study participants examined at 21,519 semi-annual visits were evaluated. Fourteen percent (391/2835) of men reported or were diagnosed with EGWs at 3% (675/21,519) of study visits. Multivariate analyses showed smoking, prior episodes of EGWs, HIV infection and CD4+ T-lymphocyte count among the infected, each differentially influenced the risk for new EGWs.
Paracrine Sonic Hedgehog Signalling By Prostate Cancer Cells Induces Osteoblast Differentiation, Samantha M Zunich, Taneka Douglas, Maria Valdovinos, Tiffany Chang
Paracrine Sonic Hedgehog Signalling By Prostate Cancer Cells Induces Osteoblast Differentiation, Samantha M Zunich, Taneka Douglas, Maria Valdovinos, Tiffany Chang
Dartmouth Scholarship
Sonic hedgehog (Shh) and components of its signalling pathway have been identified in human prostate carcinoma and increased levels of their expression appear to correlate with disease progression and metastasis. The mechanism through which Shh signalling could promote metastasis in bone, the most common site for prostate carcinoma metastasis, has not yet been investigated. The present study determined the effect of Shh signalling between prostate cancer cells and pre-osteoblasts on osteoblast differentiation, a requisite process for new bone formation that characterizes prostate carcinoma metastasis.