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Biological Sciences Undergraduate Honors Theses

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Improving Fertility: Evaluating The Addition Of Prednisone To Enhance The Effectiveness Of Clomid And Femara In Anovulatory Patients., Jeffrey Bradford May 2024

Improving Fertility: Evaluating The Addition Of Prednisone To Enhance The Effectiveness Of Clomid And Femara In Anovulatory Patients., Jeffrey Bradford

Biological Sciences Undergraduate Honors Theses

Chronic Anovulation and PCOS is a major infertility issue that affects the ability of many female patients to conceive and obtain a pregnancy. General anovulation is influenced by a combination of factors such as hypoandrogenism, hormonal imbalances, and an irregular menstrual cycle. The current methods of treatments include the usage of first-line medications such as Clomid and Femara or more expensive options such as menotropin regimens, Intrauterine Insemination (IUI), or In Vitro Fertilization (IVF). While Clomid and Femara remain the most common and successful method, an estimated 25% of general anovulation patients will fail to ovulate despite a maximum dosage …