Musculoskeletal System Commons^™

Yoga As A Didactic Tool For Musculoskeletal Anatomy For First Year Medical Students, Jennnifer Brueckner-Collins, Scott P. Stuckey

Journal of Wellness

Introduction: Medical education requires students to adjust their study habits. Active learning has been shown to enhance understanding, especially regarding anatomy. Wellness has become increasingly emphasized for medical professionals; thus, it is important for medical students to develop wellness habits to mitigate burnout. Yoga is commonly practiced with a focus on wellness and flow of movements. Yoga as an educational and wellness tool integrated into medical gross anatomy is a worthwhile pursuit. This study describes a series of anatomy-based yoga videos designed to meld wellness activities with musculoskeletal anatomy review for preclinical medical students.

Approach: Six novel yoga …

A Literature Review On The Development Of Upper Limbs In Humans, Anh T. Phan

The Cardinal Edge

The development of tetrapod upper limbs shares an evolutionary origin and has been adapted and specialized for different functions for different species, such as flight in birds, swimming and balance in sea mammals, and coordination and grabbing objects in humans. The basis of tetrapod limb development has common developmental patterns, starting with the formation of the limb bud via Sonic hedgehog (Shh) signaling, where later developmental steps are modified for specialized functions. This review covers the basic developmental patterns of mammalian tetrapod development seen in humans, beginning with the formation of the limb bud, to the axis development of the …

In Vitro Immune Activation By Treponema Pallidum And The Effect On Osteoclastogenesis: First Experimental Step Towards An Integration Between Osteoimmunology And Paleopathology., Emily Ann Rich

College of Arts & Sciences Senior Theses

The presence of pathogens in the human body influences the expression of pro-inflammatory cytokines by activated immune cells. These cytokines, and other factors, regulate osteoclastogenesis and osteoclast activity. Through experimental osteoimmunology, interactions between the inflammatory response and bone cell physiology may provide insight into how immune processes can be translated into the lesions or abnormalities observed in the osteological record. In this research, our objective was to determine if the cytokines produced by activated immune cells increase osteoclastogenesis and osteoclast activity. To evaluate this hypothesis, we used two main protocols, one for immune activation and one for osteoclastogenesis, that utilized …

Unfolded Protein Response Pathways In Skeletal Muscle Homeostasis., Kyle R. Bohnert

Electronic Theses and Dissertations

Skeletal muscle mass, contractile properties, and metabolic function are regulated through the coordinated activation of multiple intracellular signaling pathways and genetic reprogramming. The endoplasmic reticulum (ER) plays a pivotal role in protein folding and calcium homeostasis in many cell types, including skeletal muscle. Disruption of calcium levels or accumulation of misfolded proteins in the ER lumen leads to stress, which results in the activation of a signaling network called the unfolded protein response (UPR). Further, recent studies have suggested that in certain conditions, UPR pathways can be activated independent of ER stress. However, the role of ER stress and the …

Biomechanical Testing Of An Exercise For Strengthening The Proximal Femur., Alyssa Osbourne

Electronic Theses and Dissertations

Based on the principles of cutting edge bone remodeling research, a unique therapeutic exercise device was designed specifically to improve bone quality at the most critical location of the proximal femur prone to fracture: the superior-lateral femoral neck where the fracture first initiates during a fall. The exercise/device is intended to work by inducing enough strain in the bone to stimulate the body’s natural bone remodeling mechanisms to increase bone density in the proximal femur and consequently prevent a fracture from arising if a fall to the side does occur.

In order to test the proposed exercise, experiments simulating the …