Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Embryonic Structures
The Effect Of Sub 5% Oxygen Tension On In Vitro Human Embryo Development, Bradley James Link
The Effect Of Sub 5% Oxygen Tension On In Vitro Human Embryo Development, Bradley James Link
EVMS School of Health Professions Theses & Dissertations
Objective: To determine the impact of < 5% O2 tension on the in vitro development of human pre-implantation embryos. It was hypothesized that the optimal O2 tension would differ from the commonly utilized 5%, as shown by beneficial effects after the implementation of a more physiological O2 tension such as 2% for either the partial or full duration of in vitro culture.
Aim: To conduct a randomized controlled study to determine the effect of O2 tension during in vitro human embryo culture on the production of reactive oxygen species (ROS), apoptosis, gene expression and embryo development.
Background: The …