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Articles 1 - 3 of 3
Full-Text Articles in Cells
Ciliary Dysfunction In Polycystic Kidney Disease: An Emerging Model With Polarizing Potential, Robert J. Kolb, Surya M. Nauli
Ciliary Dysfunction In Polycystic Kidney Disease: An Emerging Model With Polarizing Potential, Robert J. Kolb, Surya M. Nauli
Pharmacy Faculty Articles and Research
The majority of different cell types in the human body have a cilium, a thin rod-like structure of uniquely arranged microtubules that are encapsulated by the surface plasma membrane. The cilium originates from a basal body, a mature centriole that has migrated and docked to the cell surface. The non-motile cilia are microtubule-based organelles that are generally considered sensory structures. The purpose of this review is to discuss the practicality of the ciliary hypothesis as a unifying concept for polycystic kidney disease and to review current literature in the field of cilium biology, as it relates to mechanosensation and planar …
Golgi Specificity And Development Of Autoreactive B Cells, Fazlullah Salar Khan Nawazi
Golgi Specificity And Development Of Autoreactive B Cells, Fazlullah Salar Khan Nawazi
Theses and Dissertations (ETD)
B cell receptors with certain heavy/light chain pairs predominate in the periphery of anti-DNA heavy chain transgenic mice while certain other B cell receptors are absent. We wanted to know why. To answer this, we re-constructed B cell receptors represented in the anti-DNA transgenic mice by cloning them as single chain variable fragments (scFv) to analyze their affinity to dsDNA. scFv representing receptors that were recovered from the spleens of transgenic mice had very little to no affinity to dsDNA. scFv representing receptors that were absent in the spleen had high affinity to dsDNA. We therefore concluded that receptors with …
Department Of Anatomy And Cell Biology: 1983-2007, Garl K. Rieke
Department Of Anatomy And Cell Biology: 1983-2007, Garl K. Rieke
UND Departmental Histories
This departmental history was written on the occasion of the UND Quasquicentennial in 2008.