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Articles 1 - 4 of 4
Full-Text Articles in Equipment and Supplies
Microbubble-Protected Oncolytic Virotherapy Targeted By Sonoporation Induces Tumor Necrosis And T-Lymphocyte Infiltration In Humanized Mice Bearing Triple-Negative Breast Cancer, Juliana Sitta, Flavia De Carlo, Imani Kirven, John H. Tackett, Patrice Penfornis, George Clement Dobbins, Mallory Barbier, Luis Del Valle, Clayton T. Larsen, Ernest G. Schutt, Rhodemann Li, Candace M. Howard, Pier Paolo Claudio
Microbubble-Protected Oncolytic Virotherapy Targeted By Sonoporation Induces Tumor Necrosis And T-Lymphocyte Infiltration In Humanized Mice Bearing Triple-Negative Breast Cancer, Juliana Sitta, Flavia De Carlo, Imani Kirven, John H. Tackett, Patrice Penfornis, George Clement Dobbins, Mallory Barbier, Luis Del Valle, Clayton T. Larsen, Ernest G. Schutt, Rhodemann Li, Candace M. Howard, Pier Paolo Claudio
School of Medicine Faculty Publications
Oncolytic virotherapy has shown great promise in mediating targeted tumor destruction through tumor-selective replication and induction of anti-tumor immunity; however, obstacles remain for virus candidates to reach the clinic. These include avoiding neutralizing antibodies, preventing stimulation of the adaptive immune response during intravenous administration, and inducing sufficient apoptosis and immune activation so that the body's defense can work to eradicate systemic disease. We have developed a co-formulation of oncolytic viruses (OVs) with Imagent lipid-encapsulated, perfluorocarbon microbubbles (MBs) to protect the OVs from the innate and adaptive immune system. Once inside the MB, the viral particles become acoustically active such that …
Increased Venous Access With Ultrasound Guided Ultralong Iv Placement, Daniel Purifoy
Increased Venous Access With Ultrasound Guided Ultralong Iv Placement, Daniel Purifoy
MSN Capstone Projects
Maintaining intravenous (IV) access is a vital part of providing care in critical care areas of nursing. It allows for continuous therapies, blood draws, complicated scans, and emergency treatment when needed. There are current procedures for obtaining IV access that are guaranteed to have a successful attempt and placement of a long catheter in a deeper vein. Patients that have been determined to have difficult venous access have proven to lose access quickly with an IV catheter of less than 3.18cm in length (Moy & Keeyapaj, 2017). These difficulties can cause monetary loss to the patients and hospitals, and damage …
Point-Of-Care Ultrasound (Pocus) Workshop For Internal Medicine Residents: A Pre/Post-Training Assessment Of Confidence And Knowledge, Abraham Lee, Cesar Gutierrez, Michelle Lopez
Point-Of-Care Ultrasound (Pocus) Workshop For Internal Medicine Residents: A Pre/Post-Training Assessment Of Confidence And Knowledge, Abraham Lee, Cesar Gutierrez, Michelle Lopez
MEDI 9331 Scholarly Activities Clinical Years
Across the country, internal medicine residency training programs are having difficulty figuring out how to optimally implement an effective point-of-care ultrasound training into their respective curricula. This study aimed to assess whether a week-long training course of didactics, followed by hands-on practice, improved both the confidence and knowledge skills of internal medicine residents using point-of-care ultrasound (POCUS). The trainees were asked to complete pre/post-training surveys, which tested their ability to interpret POCUS images and also asked them to score their confidence in using POCUS. Results showed a statistically significant improvement in not only their confidence in using POCUS, but also …
Qualitative Evaluation Of Data Compression In Real-Time Ultrasound Imaging, Bijoy J. Sundersingh
Qualitative Evaluation Of Data Compression In Real-Time Ultrasound Imaging, Bijoy J. Sundersingh
Theses and Dissertations (ETD)
The purpose of this project was to evaluate qualitatively real-time ultrasound imaging using objective and subjective techniques to determine the minimum bandwidth required for clinical diagnosis of various anatomical and pathological states. In the experimental setup live ultrasound video samples representing the most common clinical examinations were compressed at 128, 256, 384, 768, 1152 and 1536 kbps using a compressor-decompressor (CODEC) adhering to International Telecommunication Union (ITU-T) recommendation H.261. A protocol for qualitative evaluation was developed and subjective and objective testing were performed based on this protocol. Subjective methods comprised of inter-rater reliability tests using kappa statistics and three way …