Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons^™

Current And Emerging Therapies For Atherosclerotic Cardiovascular Disease Risk Reduction In Hypertriglyceridemia, Reed Mszar, Sarah Bart, Alexander Sakers, Daniel Soffer, Dean G. Karalis

Division of Cardiology Faculty Papers

Hypertriglyceridemia (HTG) is a prevalent medical condition in patients with cardiometabolic risk factors and is associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD), if left undiagnosed and undertreated. Current guidelines identify HTG as a risk-enhancing factor and, as a result, recommend clinical evaluation and lifestyle-based interventions to address potential secondary causes of elevated triglyceride (TG) levels. For individuals with mild to moderate HTG at risk of ASCVD, statin therapy alone or in combination with other lipid-lowering medications known to decrease ASCVD risk are guideline-endorsed. In addition to lifestyle modifications, patients with severe HTG at risk of acute pancreatitis …

Supporting Cardiac Perfusion By Preboa With Reduced Visceral Ischemia Despite Extended Occlusion, Paige Deville, John Hunt, Alan B. Marr, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, Alison Smith

School of Medicine Faculty Publications

No abstract provided.

Dissociating Statistically Determined Normal Cognitive Abilities And Mild Cognitive Impairment Subtypes With Dctclock., Emily F. Matusz, Catherine C. Price, Melissa Lamar, Rod Swenson, Rhoda Au, Sheina Emrani, Victor Wasserman, David J Libon, Louisa I. Thompson

Rowan-Virtua School of Osteopathic Medicine Departmental Research

OBJECTIVE: To determine whether the DCTclock can detect differences across groups of patients seen in the memory clinic for suspected dementia.

METHOD: Patients (n = 123) were classified into the following groups: cognitively normal (CN), subtle cognitive impairment (SbCI), amnestic cognitive impairment (aMCI), and mixed/dysexecutive cognitive impairment (mx/dysMCI). Nine outcome variables included a combined command/copy total score and four command and four copy indices measuring drawing efficiency, simple/complex motor operations, information processing speed, and spatial reasoning.

RESULTS: Total combined command/copy score distinguished between groups in all comparisons with medium to large effects. The mx/dysMCI group had the lowest total …

Synthesis And Biomedical Applications Of Hollow Iron Oxide Nanoparticles, Aloka S. Paragoda Arachchilage

Dissertations, Theses, and Capstone Projects

Nano-scale materials have gained much attention during the past few decades due to the stark differences in their properties compared to bulk material. Thus, they are being studied for a myriad of applications ranging from harnessing solar energy to diagnostics. This thesis focuses on the synthesis of hollow iron oxide nanoparticles using Galvanic replacement reactions and their application in drug delivery. Moreover, the use of a peptide precursor for the enhancement of exosomes is also discussed.

Chapter 1 discusses a simple and economical Galvanic approach used for the synthesis of hollow one-dimensional iron oxide nanotubes. In the initial reaction, the …

Does The Osteopathic Pedal Pump Reduce Lower Limb Volume In Healthy Subjects?, Jill S. Adams, Sahil H. Parikh, Brandon J. Goodwin, Donald R. Noll

Rowan-Virtua School of Osteopathic Medicine Departmental Research

CONTEXT: Lymphatic treatments are gentle and passive techniques believed to enhance movement of lymph back into the central circulatory system. Animal studies provide supportive evidence, yet there are few studies in humans.

OBJECTIVES: The aim of this study is to investigate whether the osteopathic pedal pump protocol reduces volume in the lower limbs of healthy subjects.

METHODS: A total of 30 first- and second-year medical students were recruited. Subjects were excluded from participating if they had acute asthma, chronic obstructive pulmonary disease (COPD), congestive heart failure, active infections, fractures of the lower extremities, or metastatic cancer. A within-subjects study design …

Magnetic Resonance Imaging-Derived Microvascular Perfusion Modeling To Assess Peripheral Artery Disease, Olga A. Gimnich, Tatiana Belousova, Christina M. Short, Addison A. Taylor, Vijay Nambi, Joel D. Morrisett, Christie M. Ballantyne, Jean Bismuth, Dipan J. Shah, Gerd Brunner

School of Medicine Faculty Publications

BACKGROUND: Computational fluid dynamics has shown good agreement with contrast-enhanced magnetic resonance imaging measurements in cardiovascular disease applications. We have developed a biomechanical model of microvascular perfusion using contrast-enhanced magnetic resonance imaging signal intensities derived from skeletal calf muscles to study peripheral artery disease (PAD). METHODS AND RESULTS: The computational microvascular model was used to study skeletal calf muscle perfusion in 56 in-dividuals (36 patients with PAD, 20 matched controls). The recruited participants underwent contrast-enhanced magnetic resonance imaging and ankle-brachial index testing at rest and after 6-minute treadmill walking. We have determined associations of microvascular model parameters including the transfer …

Impact Of Perioperative Dexamethasone On Hospital Length Of Stay And Glycemic Control In Patients With Type 2 Diabetes Undergoing Total Hip Arthroplasty, Vanessa Williams, Mohammad J. Uddin Ansari, Amruta Jaju, Stacey Ward, Daniel O'Keefe, Jumana Abdelkarim, Nicole Montes, Ula Tarabichi, Albert Botchway, Michael G. Jakoby Iv

Journal of Patient-Centered Research and Reviews

Purpose: This study aimed to evaluate effects of perioperative dexamethasone on hospital length of stay (LOS) and glycemic control for patients with type 2 diabetes mellitus undergoing total hip arthroplasty (THA).

Methods: We performed retrospective case review of THA performed in adults (≥ 18 years old) with type 2 diabetes at Springfield Memorial Hospital (Springfield, IL) immediately before (2013), during (2014), and after (2015) publication of consensus guidelines for use of perioperative dexamethasone. Hospital LOS was the primary endpoint. Capillary blood glucose by hospital day, proportion of patients treated with insulin, and median insulin dose by hospital day …

Estimating Dementia Risk In An African American Population Using The Dctclock, Marissa Ciesla, Jeff Pobst, Joyce Gomes-Osman, Melissa Lamar, Lisa L Barnes, Russell Banks, Ali Jannati, David Libon, Rodney Swenson, Sean Tobyne, David Bates, John Showalter, Alvaro Pascual-Leone

Rowan-Virtua School of Osteopathic Medicine Departmental Research

The prevalence of Alzheimer's disease (AD) and related dementias (ADRD) is increasing. African Americans are twice as likely to develop dementia than other ethnic populations. Traditional cognitive screening solutions lack the sensitivity to independently identify individuals at risk for cognitive decline. The DCTclock is a 3-min AI-enabled adaptation of the well-established clock drawing test. The DCTclock can estimate dementia risk for both general cognitive impairment and the presence of AD pathology. Here we performed a retrospective analysis to assess the performance of the DCTclock to estimate future conversion to ADRD in African American participants from the Rush Alzheimer's Disease Research …

Assessment Of Patient And Surgeon Perception On Prophylactic Mesh: A Standard Gamble, Kayla Nguyen, Duyen Quach, Niharika Neela, Nicole Lyons, Oscar Olavarria

Gulf Coast Division GME Research Day 2023

No abstract provided.

Implementing Point-Of-Care Ultrasound (Pocus) Training As Part Of The Curriculum For Family Medicine Residents: An Approach To Incorporate Pocus In Primary Care, Nikita Sijapati, Byron Markel, Evan Stone, Edgar Mercado

West Florida Division GME Research Day 2023

No abstract provided.

Midgut Volvulus A Rare Cause Of Acute Abdomen In The Adult Patient, Mason S. Deinema, Saptarshi Biswas

South Atlantic Division GME Research Day 2023

No abstract provided.

Documentation Burden: The Impact Of Inadequate Operative Reports On Surgrical Outcomes, Natalia Cavagnaro, Ali Siddiqui, Rainna Coelho, Nicole B. Lyons, Said Maldonado

Gulf Coast Division GME Research Day 2023

No abstract provided.

It’S A Mesh In These Bowels: Delayed Case Of Decade Long Mesh Eroding Into A Small Bowel Causing Obstruction And Intraperitoneal Sepsis, Margaret Rose, Jamie Pham, Adina Mcnair, Saptarshi Biswas

South Atlantic Division GME Research Day 2023

No abstract provided.

Are We “Pushing” Our Patients Toward Addiction? A Preliminary Post-Cesarean Survey To Quantify Narcotic Requirements For Pain Control, Aliya Nurani, Mikalah Maury, Merritt Mcgowan, Stephanie Tootle, Anthony Royek, Eric Shaw

South Atlantic Division GME Research Day 2023

No abstract provided.

Reducing Unnecessary Cbcs On The Inpatient Resident Service: Interviewing Stakeholders To Identify Underlying Causes, Feras Al-Moussally, Zara Bashir, Jorge Rodriguez, Ashlee Sidhu, Brain Murr, Liliana Franco, Jorge Restrepo, Ashwini Komarla

North Florida Division GME Research Day 2023

No abstract provided.

Confirming Diagnosis Of Copd With Spirometry, Stephan Zehring, Manal El-Hag, Gino Singer, David Nguyen, Eslam Mohamed, Michael Usbergi

North Florida Division GME Research Day 2023

No abstract provided.

Operative Management Of Grade V Liver Injury After Blunt Trauma: A Case Report, Laura Mena Albors, Garret Perry, Samantha Reiss, Darwin Ang

North Florida Division GME Research Day 2023

No abstract provided.

Technique For Osteochondral Allograft Transplant For 1st Metatarsal Head Cartilage Damage, Bren Koerner, Angela Walker, Kyle Barner, Yale Williams

Continental, MidAmerica, & Mountain Divisions GME Research Day 2023

No abstract provided.

Plantar Plate Injury: Current Treatment Options, Nehal Modha, Warren Windram

East Florida Division GME Research Day 2023

Plantar plate injuries have gained recognition as a common cause of forefoot pain and instability. This review aims to comprehensively analyze the present landscape of treatment options available for addressing plantar plate injuries.

A comprehensive literature review was completed by the authors using Google Scholar, Pubmed, Cochrane Review, and Science Direct using a combination of phrases related to the title of this article that discussed various treatment modalities for plantar plate injuries. The review encompassed both non-surgical and surgical interventions, assessing their efficacy, outcomes, and potential complications.

Conservative approaches, such as rest, taping, orthotic devices, and physical therapy, have been …

A Retrospective Study Comparing Mortality Rates Between Vaccinated And Unvaccinated Kidney Transplant Recipients, Anaam Fayyaz, Judy Pozzerle, Suresh Antony

Central & West Texas GME Research Day 2023

No abstract provided.

Is Night Time The Right Time For Hernia Surgery And Dictations, Ali Siddiqui, Nicole B. Lyons, Said Maldonado, Jonathan Lall, Brianna L. Cohen

Gulf Coast Division GME Research Day 2023

No abstract provided.

Dermatologic Manifestations Of Rheumatic Disease: Cutaneous Manifestations Of Vasculitides, Julianna S. Kang, Julia Nunley, Tiffany Ho, Mavra Masood, Fnu Nutan, Beth Rubinstein

Open and Affordable Course Content at VCU

No abstract provided.

The Treatment Of Depression In Alzheimer's Disease Using Neuromodulation: A Literature Review, Aaron Marbn, Shane Ragland, Thalia Adrian, Clara Alvarez Villalba, Samuel Neuhut

East Florida Division GME Research Day 2023

Please see supplemental content for full abstract with references.

INTRODUCTION: An estimated 44 million individuals live with Alzheimer's Dementia globally, a number expected to triple by 2050.1 Depression is a commonly observed comorbidity in individuals with Alzheimer's disease. Traditional antidepressant medications often pose challenges due to their side effects and limited efficacy in this population. As a result, alternative therapeutic approaches are being explored, with Transcranial Magnetic Stimulation (TMS) emerging as a promising intervention for treating depression in Alzheimer's patients. TMS is a non-invasive brain stimulation technique that utilizes magnetic fields to modulate neural activity in targeted brain regions …

Mesenchymal Stem Cell Use In The Treatment Of Osteoarthritis: A Literature Review, Samantha Arrizon, Nolan Barnes, Teresa Del Toro, Lei Wena Herme, Vanessa Mendoza, Thi Tran, Reeta Zamro

Physician Assistant Studies | Student Literature Reviews

Mesenchymal stem cell (MSC) therapies have been growing in popularity in research due to their anti-inflammatory, immunomodulatory, and regenerative properties. Many ongoing clinical trials are investigating the safety and efficacy of MSC therapies to treat osteoarthritis, also known as “wear and tear” arthritis. As the average life expectancy increases, with age people are more prone to developing this disease, therefore, increasing its prevalence. This condition is progressive and will lead to functional decline, decreased quality of life, and increased medical costs. Our focus is to discuss the efficacy of mesenchymal stem cell injections in alleviating pain, improving functionality, and slowing …

The Role Of Preoperative Magnetic Resonance Cholangiopancreatography/Endoscopic Retrograde Cholangiopancreatography In The Setting Of Mildly Elevated Liver Enzymes Prior To Cholecystectomy, Rachel Groening, Salah Abdel Jalil, Jeffery Durbin, Rahul Kashyap, Aaron D. Pinnola

South Atlantic Division GME Research Day 2023

No abstract provided.

A Standardized Protocol For Remote Outpatient Blood Pressure Management, Nicholas Dorsey, Justin Taylor, Elvira Mercado

North Florida Division GME Research Day 2023

No abstract provided.

Investigating Association Between Sociographic Factors And Rates Of Urine Drug Screening In Patients Admitted To Labor And Delivery: A Retrospective Analysis, Erin Manglardi, Donna Boucher

North Florida Division GME Research Day 2023

No abstract provided.

To Echo Or Not To Echo: Improving Appropriate Use Of Echocardiography In Evaluation Of Syncope, William Hicks, Cindy Iwuagwu, Suzan Khalil, Juan Pablo Meruvia Garron, Cynthia Schwartz, Floyd Burke

North Florida Division GME Research Day 2023

No abstract provided.

Race/Ethnicity And Morbidity/Mortality In Laparoscopic Cholecystectomy: 2016 Usa Study, Victorien Meray, Rupa Seetharamaiah

East Florida Division GME Research Day 2023

Background: Social determinants of health, such as race and ethnicity, can have a significant impact on people's health and well-being. People of color are more likely to experience poverty, lack of access to healthcare, and discrimination, which can lead to worse health outcomes. Laparoscopic cholecystectomy is a surgical procedure to remove the gallbladder. It is the most common gastrointestinal surgery performed in the United States. In this study, we sought to determine if there is an association between race/ethnicity and morbidity/mortality in adult patients undergoing laparoscopic cholecystectomy.

Methods: We conducted a non-concurrent cohort study of patients over 18 years old …

Giant Mesenchymal Hepatic Hamartomas With Adrenal Involvement Precipitating Respiratory Failure: A Myxomatous Mystery In A 3 Month Old, Ali Yasback, Abid Ulhaque, Tushar Chandra, Sandor Szilagyi

West Florida Division GME Research Day 2023

No abstract provided.