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Jefferson Alumni Bulletin – Volume Xlv, Number 3, June 1996

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLV, Number 3, June 1996

Student Initiative and New Educational Challenges Converge in Community Primary Care, Page 4

Methodist Hospital and Thomas Jefferson University Hospital Merge Services, page 13

Kimmel Foundation Donates $10 Million, Establishing the Kimmel Cancer Center, Page 13

Capizzi Succeeds Caro as Chairman of Medicine, Page 17

DiMarino Appointed Chief of Gastroenterology, Page 17

Book Portrays C. Earl Albrecht ’32 in Alaska, Page 22

Leonard Zon ’83 Continues in Erslev’s Footsteps, Page 25

Jefferson Alumni Bulletin – Volume Xlv, Number 2, March 1996

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLV, Number 2, March 1996 A Conversation with the Alumni Chairman of Family Medicine, Page 4 Stanton N. Smullens ’61: Jefferson Leader, Page 14 Hospital Separates from University as Step in Forming the Jefferson Health System, Page 15 Gene That Helps Cause Gliomas is Identified, Page 16 Altered FHIT Gene is Found in Several Types of Common Cancers, Page 17 Vaccine Treats Rheumatoid Arthritis, Page 18 Blood Test Can Measure Obesity Hormone, Page 19 Gene Therapy for HIV-Infected Patients Will Begin Here, Page 21 Spitzer Authors Neonatology Text, Page 23 Gallo Discovers HIV-Suppresor Factors, page …

Jefferson Alumni Bulletin – Volume Xlv, Number 1, December 1995

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLV, Number 1, December 1995

We will fight cancer with molecular therapeutics and prediagnostics, page 4

Behavior and economics will challenge prevention, page 6

From genetic understanding to cure, page 9

Computer-based teaching reshapes how students learn, page 12

Will tomorrow’s journals be electronic? Page 14

Jefferson health system upgrades its information technology, page 17

Molecule essential for cell growth and division is discovered at Jeff, page 19

Jefferson Alumni Bulletin – Volume Xliv, Number 4, September 1995

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIV, Number 4, September 1995 Anniversary galas, page 4 and 24 Jefferson health system in established by the university and main line health, page 12 Research, page 14 Appointments, page 20 Books, page 22 Journal of neurovirology is founded, page 22

Department Of Radiology-Annual Report-July 1, 1994 To June 30, 1995, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1994 to June 30, 1995. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 120 pages.

Increased Abundance Of The Receptor-Type Protein-Tyrosine Phosphatase Lar Accounts For The Elevated Insulin Receptor Dephosphorylating Activity In Adipose Tissue Of Obese Human Subjects, Falyaz Ahmad, Robert V. Considine, Barry J. Goldstein

Department of Medicine Faculty Papers

Protein-tyrosine phosphatases (PTPases) have an essential role in the regulation of the steady-state phosphorylation of the insulin receptor and other proteins in the insulin signalling pathway. To examine whether increased PTPase activity is associated with adipose tissue insulin resistance in human obesity we measured PTPase enzyme activity towards the insulin receptor in homogenates of subcutaneous adipose tissue from a series of six lean and six nondiabetic, obese (body mass index > 30) subjects. The obese subjects had a mean 1.74-fold increase in PTPase activity (P < 0.0001) with a striking positive correlation by linear regression analysis between PTPase activity and body mass index among all of the samples (R = 0.918; P < 0.0001). The abundance of three candidate insulin receptor PTPases in adipose tissue was also estimated by immunoblot analysis. The most prominent increase was a 2.03-fold rise in the transmembrane PTPase LAR (P < 0.001). Of the three PTPase examined, only immunodepletion of LAR protein from the homogenates with neutralizing antibodies resulted in normalization of the PTPase activity towards the insulin receptor, demonstrating that the increase in LAR was responsible for the enhanced PTPase activity in the adipose tissue from obese subjects. These studies suggest that increased PTPase activity towards the insulin receptor is a pathogenetic factor in the insulin resistance of adipose tissue in human obesity and provide evidence for a potential role of the LAR PTPase in the regulation of insulin signalling in disease states.

1995 Commencement For College Of Allied Health Sciences

Jefferson College of Nursing Commencements

No abstract provided.

Jefferson Alumni Bulletin – Volume Xliv, Number 3, Spring 1995

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIV, Number 3, Spring 1995

A brief history, page 4

Then and now, page 9

Views of the campus, page 14

Jefferson facts, page 14

A host of remarkable graduates, page 17

Jefferson looks to the future, page 20

Jefferson Alumni Bulletin – Volume Xliv, Number 2, Winter 1994-1995

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIV, Number 2, Winter 1994-1995 College of allied health sciences and medical college collaborate, page 4 Diabetes prevention study, page 6 With outside funding, JeffCARES becomes part of curriculum, page 10 JeffMOMS Teaches freshmen, page 11 Students come by many routes to Jefferson, page 12 West Jersey health system joins Jefferson in healthshare group, page 15 Working on health care reform, page 22 Books, page 14 Bone marrow transplant center established under Flomenberg, page 16 Farber chairs board of trustees, page 16 Spitzer is pediatrics chair, page 17 Neurosensory institute’s unusual surgery saves infant, page …

Jefferson Alumni Bulletin – Volume Xliii, Number 3, Fall 1994

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIII, Number 3, Fall 1994 Diary of an SCI, page 5 Colleagues honor Cotler with portrait, page 7 Neurosensory institute is established, department of neurosurgery expands, page 7 Teaching molecular medicine, preparing for practice in the 21st Century, page 8 On campus, page 11 Jefferson Research, page 12 Giving to Jefferson, page 14 Obituaries, page 16 Class notes, page 18

A Randomized Comparison Of Coronary-Stent Placement And Balloon Angioplasty In The Treatment Of Coronary Artery Disease. Stent Restenosis Study Investigators., David L. Fischman, Martin B. Leon, Donald S. Baim, Richard A. Schatz, Michael P. Savage, Ian Penn, Katherine Detre, Lisa Veltri, Donald Ricci, Masakiyo Nobuyoshi, Michael Cleman, Richard Heuser, David Almond, Paul S. Teirstein, R. David Fish, Antonio Colombo, Jeffrey Brinker, Jeffrey Moses, Alex Shaknovich, John Hirshfeld, Stephen Bailey, Stephen Ellis, Randal Rake, Sheldon Goldberg

Department of Medicine Faculty Papers

BACKGROUND: Coronary-stent placement is a new technique in which a balloon-expandable, stainless-steel, slotted tube is implanted at the site of a coronary stenosis. The purpose of this study was to compare the effects of stent placement and standard balloon angioplasty on angiographically detected restenosis and clinical outcomes.

METHODS: We randomly assigned 410 patients with symptomatic coronary disease to elective placement of a Palmaz-Schatz stent or to standard balloon angioplasty. Coronary angiography was performed at base line, immediately after the procedure, and six months later.

RESULTS: The patients who underwent stenting had a higher rate of procedural success than those who …

Jefferson Alumni Bulletin – Volume Xliii, Number 4, Summer 1994

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIII, Number 4, Summer 1994

The social transformation of practice, page 8

How medicine is taught differently now, page 8

The only constant is change, page 8

Medicine is being challenged and physicians must respond, page 8

Vascular Ectasias of the colon, page 9

Jefferson and AIDS care in Uganda, page 10

Laparoscopic cholecystectomy at Pennsylvania hospital, page 10

Nintendo comes to medicine: 3-D MRI of congenital heart disease, page 11

Imaging of psychiatric conditions, page 12

Effects of space flight on human physiology: A Jefferson Study, page 12

Aesthetic considerations after trauma, page 13 …

Department Of Radiology-Annual Report-July 1, 1993 To June 30, 1994, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1993 to June 30, 1994. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 107 pages.

The Board Of Trustees: An Indispensable Asset, Frederick B. Wagner, Jr.

Jefferson History Books

A history of Thomas Jefferson University's Board of Trustees, from 1826-1994.

Jefferson Alumni Bulletin – Volume Xliii, Number 3, Spring 1994

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIII, Number 3, Spring 1994

Anesthesiology is never at rest, page 2

The medical college’s past ten years and its future, page 8

New health care climate, page 13

Student life, page 15

Books, page 14

Albuterol may increase the effectiveness of Parkinson’s disease therapy, page 16

NIH Continues support for scleroderma research, page 16

Faculty number among area’s most cited scientists, page 16

On campus, page 16

Class notes, page 22

Jefferson Alumni Bulletin – Volume Xliii, Number 2, Winter 1993-1994

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIII, Number 2, Winter 1993-1994

Strong surgical staff broadens research, page 3

PHO will merge the faculty and the hospital into one legal entity, page 8

How health care reform may impact teaching and research, page 8

M.D. /M.B.A. and M.D. /M.H.A. will be offered, page 8

Jefferson will work closely with Pennsylvania hospital, page 9

Someone will chair neurosurgery, page 9

On campus, page 11

Research, page 12

Chemotherapy prior to surgery helps at stage III, page 12

Lumpectomy combined with radiation implants, page 12

Elections/Appointments, page 14

Class notes, page 21

Jefferson Alumni Bulletin – Volume Xlii, Number 1, Fall 1993

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLII, Number 1, Fall 1993

House staff receive a comprehensive preparation, page 2

Rectal cancer management arrives on the threshold of synergy with basic research, page 6

Fry is the first marks professor, page 8

Funding completed for the kind professorship, page 9

Bibbo is the first Lang professor, page 10

Institute for dermatopathology, page 11

Joslin center for diabetes, page 11

$54 million in awards in 1993, page 12

Blood substitute is refined, page 12

Study suggests site of alcohol and anesthesia action, page 13

Computers assist drug design, page 13

Clinton aide discusses …

Jefferson Alumni Bulletin – Volume Xlii, Number 4, Summer 1993

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLII, Number 4, Summer 1993

The development of surgery for heart disease, page 6

Refining the heart-lung machine, page 9

Training surgical residents, page 10

Counseling in family medicine, page 10

Volunteer care in Swaziland, page 10

Paleoradiology of the prehistoric Australian aborigines, page 11

Vaccine therapy of melanoma, page 12

Biliary radiology and T tube design, page 13

Familial patterns of ovarian carcinoma, page 15

The importance of treating diabetic retinopathy, page 16

Investigators identify key protein causing heart muscle damage after heart attack, page 18

Croce wins Mott Prize, page 19

Westermark given …

Department Of Radiology-Annual Report-July 1, 1992 To June 30, 1993, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1992 to June 30, 1993. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 85 pages.

Jefferson Alumni Bulletin – Volume Xlii, Number 3, Spring 1993

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLII, Number 3, Spring 1993

Genetic factors behind behavioral disorder are at the center of department research, page 2

Baldwin L. Keyes, ’17: A career through many countries, battles, and specialties, page 5

Baldwin L. Keyes, ’17: A chairman who taught by personal example, page 7

Committee provides guidance on ethical issues that underlie clinical cases, page 9

John E. Deitrick, M.D.: Early appraiser of medical education, page 12

Scientists link nitric oxide to brain damage in neurologic viral diseases, page 14

Study shows Jefferson succeeds in training rural physicians, page 15

Students help organize …

Jefferson Alumni Bulletin – Volume Xlil, Number 2, Winter 1993

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIL, Number 2, Winter 1993 New technology, new faculty, and new productivity Mark Jefferson Radiology, page 2 An early contract for medical care, page 10 Jefferson meets the challenges of geriatric medicine, page 11 Students establish a community outreach initiative, page 14 What does a Jefferson medical college diploma mean to me? Page 16 Jefferson discoveries May help show how to keep AIDS dormant, page 18 Genetic cause of common leukemia is found here, page 19 Alcohol research center receives $8 million grant to continue basic investigations, page 20 Use of decoy peptides to block …

Jefferson Alumni Bulletin – Volume Xlii, Number 1, Fall 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLII, Number 1, Fall 1992

New challenges are met successfully, page 2

The longitudinal study, page 4

Changes strengthen curriculum, page 6

Applications reach all-time high, page 7

The critical link between clinical practice and basic science, page 8

Drive to raise $200 million is in high gear, page 12

Hamilton professors are named, page 13

New Rorer professor, page 14

Endocrinology director appointed, page 14

Bequest from dubbs, ’31 establishes fellowships, page 15

New associate Dean, page 15

$5 million grant made to Jefferson cancer institute, page 16

President Brucker is welcomed in Washington, …

Jefferson Alumni Bulletin – Volume Xli, Number 4, Summer 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLI, Number 4, Summer 1992

Malignant bone tumors developing at sites of benign preexisting bone disease, page 13

An experience with a small rural hospital, page 15

The prevention of Turista and the enjoyment of foreign travel, page 16

The Nemours children’s clinic, page 17

The shoulder revisited, page 19

Jeff’s trauma program, page 20

The biochemical basis for diabetic nephropathy, page 21

Dealing with the media, page 23

Space motion sickness, page 24

Total joint replacement, page 25

Decision making and the doctor-patient relationship, 26

New endowed chair, page 30

Inaugural grandon lecture, page …

Department Of Radiology-Annual Report-July 1, 1991 To June 30, 1992, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1991 to June 30, 1992. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 72 pages.

Insulin Receptor And Epidermal Growth Factor Receptor Dephosphorylation By Three Major Rat Liver Protein-Tyrosine Phosphatases Expressed In A Recombinant Bacterial System, Naotake Hashimoto, Wei-Ren Zhang, Barry J. Goldstein

Department of Medicine Faculty Papers

Protein-tyrosine phosphatases (PTPases) play an essential role in the regulation of signal transduction mediated by reversible protein-tyrosine phosphorylation. In order to characterize individual rat hepatic PTPases that might have specificity for autophosphorylated receptor tyrosine kinases, we isolated cDNA segments encoding three PTPases (PTPase 1B, LAR and LRP) that are expressed in insulin-sensitive liver and skeletal muscle tissue, and evaluated their catalytic activity in vitro. The intrinsic PTPase activities of the full-length PTPase 1B protein and the cytoplasmic domains of LAR and LRP were studied by expression of recombinant cDNA constructs in the inducible bacterial vector pKK233-2 using extracts of …

Jefferson Alumni Bulletin – Volume Xli, Number 3, Spring 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLI, Number 3, Spring 1992

State of the division 1992, page 2

Interviews with two distinguished faculty members, page 5

Programs link Alumni and students, page 9

Robert Gallo, ’63 and the human element, page 10

On campus, page 14

Drawing on his medical knowledge, page 17

American psychiatric association chooses Joseph T. English, ’58 as president, page 19

Class notes, page 24

Jefferson Alumni Bulletin – Volume Xli, Number 2, Winter 1992

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLI, Number 2, Winter 1992

The Medical Scholars Program, page 2

Jefferson and Cancer Research, page 6

The Cardeza Foundation for Hematologic Research, page 9

The Contribution of Frederick Roscher to Jefferson's Art Collection, page 14

Multidisciplinary Research and a Broader Teaching of Outpatient Medicine Are Planned by the New Chairman of Medicine, page 17

On Campus, page 18

Class Notes, page 23

Jefferson Alumni Bulletin – Volume Xli, Number 1, Fall 1991

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLI, Number 1, Fall 1991 Can Jefferson provide quality care and still contain costs? Page 2 A love for rural medicine, page 5 A nineties practice in the Susquehanna valley, page 8 The roundabout, page 11 Cardeza foundation celebrates 50 years of research closely linked to patient care, page 12 Acquiring our portraits of Franklin and Jefferson, page 14 On campus, page 19 Class notes, page 20

Jefferson Alumni Bulletin – Volume Xl, Number 4, Summer 1991

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XL, Number 4, Summer 1991

Clinic presentations, page 9

Honoring our Dean and our Counselor, page 26

A research building for building research, page 28

“Health care: a right or a privilege?” Page 35

On campus, page 36

Class notes, page 38

Department Of Radiology-Annual Report-July 1, 1990 To June 30, 1991, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1990 to June 30, 1991. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 84 pages.