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Truth And Healing A Veteran's Depression, Mike W. Martin

Philosophy Faculty Articles and Research

Comments on an article by Christopher Bailey (see record 2009-24345-002). Dr. Christopher Bailey portrays an American veteran, Colin, who slips into a "serious but not severe" depression upon returning from the Iraq War, After ruling out post-traumatic stress disorder, the psychiatrist comes to believe that Colin's depression is tied to his feelings of being a wimp, of not having "done his part or proven his manhood," and of losing his chance to become a hero because he had been assigned non-combat duty—feelings that the psychiatrist glosses (misleadingly?) as a "painful lack of wounds." (I speak of the "the psychiatrist," rather …

Traumatic Stress As A Predictor Of Suicidality, Sherry Malana Todd

Counseling & Human Services Theses & Dissertations

Suicide is a deliberate act of annihilation against one's self due to a crisis of problem solving. Far too many youth are dying by their own hands resulting in suicide being the third leading cause of death for 10-19 year olds (CDC, 2005). Suicide is particularly problematic for adolescents due to the impulsivity inherent in adolescent development. Since 1980, the national suicide rate of African American youth has increased by 114 percent (CDC). Suicidality has been positively correlated with depression and posttraumatic stress disorder (PTSD; Kessler et al., 1999). Suicidality is more prevalent when a person experiences a tragic or …

Psychiatric Illness In The Next-Of-Kin Of Intensive Care Unit Patients, Janelle Katie Moulder

Yale Medicine Thesis Digital Library

The prevalence of psychiatric symptoms in next-of-kin (NOK) of intensive care unit (ICU) patients has been reported at higher than 70% when screening is performed using the Hospital Anxiety and Depression Scale (HADS). The primary purpose of this study was to assess the ability of the HADS to predict psychiatric illness, diagnosed with the aide of a validated tool, the Structured Clinical Interview for DSM-IV (SCID). In addition, we asked NOK to rate aspects of the ICU experience to determine possible associations with psychiatric diagnosis. Thirty-four NOK were enrolled in this study from July 2006 to November 2006. Subjects were …

Risk Factors For Depression In Multiple Sclerosis Patients, Funda Kaplan, Mehmet Hami̇t Boztaş, Canan Yücesan, Yasemi̇n Genç, Nezi̇h Yücemen, Nermi̇n Mutluer

Turkish Journal of Medical Sciences

Aim: A search of the English language literature found only one study that reported there was no relationship between depression and functional systems impairment based on Kurtzke's functional systems score in MS patients. The present cross-sectional study was planned to test that result. Materials and Methods: The study included 37 relapsing-remitting MS patients (25 female, 12 male) with an Expanded Disability Status Scale score Keywords: Multiple sclerosis, depression, cerebellum

Resting State Default-Mode Network Connectivity In Early Depression Using A Seed Region-Of-Interest Analysis: Decreased Connectivity With Caudate Nucleus, Robyn Bluhm, Peter Williamson, Ruth Lanius, Jean Théberge, Maria Densmore, Robert Bartha, Richard Neufeld, Elizabeth Osuch

Philosophy Faculty Publications

Aim: Reports on resting brain activity in healthy controls have described a default-mode network (DMN) and important differences in DMN connectivity have emerged for several psychiatric conditions. No study to date, however, has investigated resting-state DMN in relatively early depression before years of medication treatment. The objective of the present study was, therefore, to investigate the DMN in patients seeking help from specialized mental health services for the first time for symptoms of depression.

Methods: Fourteen depressed subjects and 15 matched controls were scanned using 4-T functional magnetic resonance imaging while resting with eyes closed. All but one subject was …

Inhibition Of Pro-Inflammatory Processes Reduces Sensitization Of The Behavioral Response To Maternal Separation, Kristopher Doojin Paik

Browse all Theses and Dissertations

The current study examined the behavioral sensitization of guinea pig pups in response to consecutive days of maternal separation. In the first experiment, guinea pigs that received centrally administered artificial cerebrospinal fluid or IL-10 exhibited sensitization of passive behaviors from Day 1 to Day 2. IL-10 decreased the levels of passive behaviors on Day 1, as well as the increase on Day 2. The second experiment used unoperated pups, which also showed sensitization of the passive response from Day 1 to Day 2, though the effect appeared reduced relative to control pups of Experiment 1. Collectively, this investigation confirms previous …

Elevated Corticotropin-Releasing Hormone In Human Pregnancy Increases The Risk Of Postpartum Depressive Symptoms, Ilona S. Yim, Laura M. Glynn, Christine Dunkel Schetter, Calvin J. Hobel, Aleksandra Chicz-Demet, Curt A. Sandman

Psychology Faculty Articles and Research

Postpartum depression (PPD) is common and has serious implications for the mother and her newborn. A possible link between placental corticotropin-releasing hormone (pCRH) and PPD incidence has been discussed, but there is a lack of empirical evidence.

Depressive Symptoms In Elderly Women With Chronic Conditions: Measurement Issues, Jaclene A. Zauszniewski, Abir K. Bekhet

College of Nursing Faculty Research and Publications

Objective: Depression is highly prevalent in elderly women with chronic conditions and measuring depressive symptoms is complicated by co-occurring chronic illnesses. The 20-item Center for Epidemiological Studies Depression (CES-D) Scale is commonly used with elders, but its length may result in missing data. Twelve short four to 16 item CES-D forms exist, but their psychometric properties have not been systematically evaluated.

Method: This study of 250 elderly women compared reliability and validity estimates for the 20-item CES-D and its 12 short forms; all scales used four response alternatives. The study also investigated whether women with varying numbers of chronic conditions …

Small Individual Loans And Mental Health: A Randomized Controlled Trial Among South African Adults, Lia C. H. Fernald, Rita Hamad, Dean Karlan, Emily J. Ozer, Jonathan Zinman

Dartmouth Scholarship

Background: In the developing world, access to small, individual loans has been variously hailed as a poverty-alleviation tool – in the context of "microcredit" – but has also been criticized as "usury" and harmful to vulnerable borrowers. Prior studies have assessed effects of access to credit on traditional economic outcomes for poor borrowers, but effects on mental health have been largely ignored.

Methods: Applicants who had previously been rejected (n = 257) for a loan (200% annual percentage rate – APR) from a lender in South Africa were randomly assigned to a "second-look" that encouraged loan officers to approve their …

Widowhood And The End Of Spousal Caregiving: Wear And Tear Or Relief?, Jennifer Reid Keene, Anastasia H. Prokos

Sociology Faculty Research

This paper analyses the impact of spousal care-giving on survivors’ depressive symptoms six months into widowhood, and examines the applicability of a ‘ relief model’ of spousal adjustment during bereavement. We examine several aspects of the care-giving situation, including care-giver stress, care-giving demands, and type and duration of care and how these affect survivors’ depressive symptomatology. The sample is drawn from two waves of the Changing Lives of Older Couples (CLOC) survey, which was conducted in the United States in the Detroit Metropolitan Area, Michigan. The first wave of data was collected from couples and the second from the surviving …

Pegylated Interferon 2a And 2b In Combination With Ribavirin For The Treatment Of Chronic Hepatitis C In Hiv Infected Patients., Ravinder Dhillon, Simona Rossi, Steven K Herrine

Department of Medicine Faculty Papers

Coinfection with hepatitis C virus (HCV) and HIV is an increasingly recognized clinical dilemma, particularly since the advent of highly active antiretroviral therapy. Several studies of this population have demonstrated both more rapid progression of liver disease and poorer overall prognosis compared to HCV monoinfected patients. Consensus guidelines, based primarily on the results of 4 major randomized trials, recommend treatment with peginterferon and ribavirin for 48 weeks in coinfected patients. However, this current standard of care is associated with lower response rates to therapy than those seen in monoinfected patients. Important predictors of response include HCV genotype, pretreatment HCV RNA …

Mood Symptoms As Comorbidity In Schizophrenia, Amresh Srivastava

Psychiatry Presentations

No abstract provided.

Quality Of Life And Depression In Breast Cancer Patients After Surgery In King Chulalongkorn Memorial Hospital, P. Malarat, N. Pityaratstian

Chulalongkorn Medical Journal

No abstract provided.

Predictors Of Depressive And Anxiety Symptoms Among African American Hiv-Positive Women, Nina Katherine Sublette

Theses and Dissertations (ETD)

This descriptive correlation study had four purposes: describe depressive and anxiety symptom levels in pregnant and non-pregnant African American (AA) HIV-positive women, examine the association between underlying vulnerabilities and depressive symptoms in HIV-positive AA women, determine the association between underlying vulnerabilities and anxiety symptoms in AA HIV-positive women, and determine the predictors of depressive and anxiety symptoms among African American HIV-positive women. A convenience sample of 80 African American HIV-positive women was recruited from university-based obstetrics/-gynecology and infectious disease practices in a large metropolitan city in the Mid-South. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale …

Depression In Parkinson's Disease: Health Risks, Etiology, And Treatment Options, Pasquale G. Frisina, Joan C. Borod, Nancy S. Foldi, Harriet R. Tenenbaum

Publications and Research

Depression is found in about 30%-40% of all patients with Parkinson's disease (PD), but only a small percentage (about 20%) receive treatment. As a consequence, many PD patients suffer with reduced health-related quality of life. To address quality of life in depressed PD patients, we reviewed the literature on the health correlates of depression in PD (eg, cognitive function), etiology of depression in PD, and treatment options (ie, antidepressants, electroconvulsive therapy, and psychotherapy). The current review is unique in its focus on psychosocial aspects, as well as neuropathological factors, of depression in PD. Overall, we conclude that neurochemical (eg, serotonin) …

Resting And Reactive Frontal Brain Electrical Activity (Eeg) Among A Non-Clinical Sample Of Socially Anxious Adults: Does Concurrent Depressive Mood Matter?, Elliott A. Beaton, Louis A. Schmidt, A R. Ashbaugh, D L. Santesso, M M. Antony, R E. Mccabe

Psychology Faculty Publications

A number of studies have noted that the pattern of resting frontal brain electrical activity (EEG) is related to individual differences in affective style in healthy infants, children, and adults and some clinical populations when symptoms are reduced or in remission. We measured self-reported trait shyness and sociability, concurrent depressive mood, and frontal brain electrical activity (EEG) at rest and in anticipation of a speech task in a non-clinical sample of healthy young adults selected for high and low social anxiety. Although the patterns of resting and reactive frontal EEG asymmetry did not distinguish among individual differences in social anxiety, …

Diverse Antidepressants Increase Cdp-Diacylglycerol Production And Phosphatidylinositide Resynthesis In Depression-Relevant Regions Of The Rat Brain, Kimberly R. Tyeryar, Ashiwel S. Undieh, Habiba Ou Vongtau

Publications and Research

Background: Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain regions associated with the disease. Monoamine transmitters activate multiple signaling cascades some of which have been investigated as potential mediators of depression or antidepressant drug action. However, the diacylglycerol arm of phosphoinositide signaling cascades has not been systematically investigated, even though downstream targets of this cascade have been implicated in depression. With the ultimate goal of uncovering the primary postsynaptic actions that may initiate cellular antidepressive signaling, we …

A Review Of The Tripartite Model For Understanding The Link Between Anxiety And Depression In Youth, Emily R. Anderson, Debra A. Hope

Department of Psychology: Faculty Publications

Although research from numerous investigations indicates that there is substantial overlap in anxiety and depressive symptoms and comorbid diagnoses in youth, these constructs can be adequately differentiated. Clark and Watson [Clark, L. A. & Watson, D., (1991). Tripartite model of anxiety and depression: Psychometric evidence and taxonomic implications. Journal of Abnormal Psychology, 100: 316-336] proposed a tripartite model to account for the symptom overlap and diagnostic comorbidity between anxiety and depression. This tripartite model posits that anxiety and depression share a common component of negative affect, but can be differentiated by low positive affect associated with depression and high …

Treating The Whole Child: Recognizing And Addressing Depression In Children With Physical Disabilities, Kathleen A. Koehn

Occupational Therapy Capstones

The purpose of this scholarly project was to develop a tool that would assist occupational therapy practitioners working with children with physical disabilities in recognizing and addressing symptoms of depression in that population. Ailey (2003) reported that symptoms of depression in children with developmental disabilities are frequently attributed incorrectly to a child's primary diagnosis, rather than depression. Because occupational therapists typically see these children more frequently than primary care physicians, they are in a prime position to assist in the screening and referral processes related to depression.

This project involved a comprehensive review of the literature, including data on the …

Peer Victimization, Depression, And Suicidality In Adolescents, Anat Brunstein Klomek, Frank Marrocco, Marjorie Kleinman, Irvin Sam Schonfeld, Madelyn S. Gould

Publications and Research

The association between specific types of peer victimization with depression, suicidal ideation, and suicide attempts among adolescents was examined. A self-report survey was completed by 2,342 high-school students. Regression analyses indicated that frequent exposure to all types of peer victimization was related to high risk of depression, ideation, and attempts compared to students not victimized. Infrequent victimization was also related to increased risk, particularly among females. The more types of victimization the higher the risk for depression and suicidality among both genders. Specific types of peer victimization are a potential risk factor for adolescent depression and suicidality. It is important …

The Prevalence Of Delinquency In Depressed And Substance Abusing Adolescent Girls, Susan C. Hunt

Antioch University Dissertations & Theses

Research conducted on the role of depression in delinquency among adolescent girls has found that depression can predict delinquency. It has been indicated that research should be conducted on how substance use and abuse play a role in depression and delinquency. Several studies have been conducted on adolescent girls in juvenile delinquent centres and institutions. Few studies have sampled subjects from community-based resources, i.e., street youth clinics, youth programs, or alternative schools. The central goal of the study was to explore delinquency in a group of depressed and substance-abusing adolescent girls in community-based settings including street clinics, youth programs, and …

Negative Mood Regulation Mediates The Relationship Between Distraction And Engagement In Pleasurable Activities Among College Smokers, Lee M. Cohen, Dennis E. Mcchargue, Holly E. R. Morrell

Department of Psychology: Faculty Publications

Smoking for negative mood alleviation is a strong predictor of early smoking and early dependence among undergraduates. Little is known about whether adaptive cognitive coping processes (e.g., distraction) may help decrease the likelihood of student smoking for negative mood regulation. The present study tested the hypothesis that distraction would predict (a) greater engagement in adaptive pleasant pastimes and (b) lower rates of smoking behavior among undergraduates (n = 162, 41.9% female). We further assessed whether negative mood regulation expectations would explain both relationships. Results indicated that negative mood regulation fully mediated the relationship between distraction and engagement in pleasurable …

Fluoxetine, Smoking, And History Of Major Depression: A Randomized Controlled Trial, Bonnie Spring, Neal Doran, Sherry Pagoto, Dennis E. Mcchargue, Jessica Werth Cook, Katherine Bailey, John Crayton, Donald Hedecker

Department of Psychology: Faculty Publications

The study was a randomized placebo-controlled trial testing whether fluoxetine selectively enhances cessation for smokers with a history of depression. Euthymic smokers with (H+, n = 109) or without (H-, n = 138) a history of major depression received 60 mg fluoxetine or placebo plus group behavioral quit-smoking treatment for 12 weeks. Fluoxetine initially enhanced cessation for H+ smokers (p = .02) but subsequently impaired cessation regardless of depressive history. Six months after quit date, fluoxetine-treated participants were 3.3 times more likely to be smoking (p = .02). Further research is warranted to determine why high-dose fluoxetine produces …

Depression In The Elderly: Does Family System Play A Role? A Cross-Sectional Study, Ather M. Taqui, Ahmed Itrat, Waris Qidwai, Zeeshan Qadri

Department of Family Medicine

Background

The most common geriatric psychiatric disorder is depression. The role of family systems in depression among the elderly has not been studied extensively. It has been suggested that urbanization promotes nucleation of family systems and a decrease in care and support for the elderly. We conducted this study in Karachi, a large urban city of Pakistan, to determine the relationship between the type of family system and depression. We also determined the prevalence of depression in the elderly, as well as correlation of depression with other important socio-demographic variables.

Methods

A cross-sectional study was carried out in the premises …

Rural Women With Disabilities And Depression, Part One: Characteristics And Treatment Patterns, Rosemary Hughes, University Of Montana Rural Institute

Health and Wellness

Depression is a common mental health problem in which a person may experience persistent sadness, be unable to enjoy formerly pleasurable activities, and feel worthless or hopeless. Undetected and untreated depression causes substantial physical and social limitation and may lead to suicidal thoughts or actions. More than 80% of people with depression improve with appropriate treatment (National Institute of Mental Health [NIMH], 2005).

Screening For Postpartum Depression At Well-Baby Visits, Suzanne Mello

Master's Projects

Objective: To assess the prevalence of postpartum depression among mothers who attend first-year well-baby visits. Methods: A convenience sample of 33 women was screened during first year well-baby visits using the Edinburgh Postpartum Depression Scale (EPDS) at three pediatric offices in Northern California. Measures included demographic data, history of depression, tobacco use, strength of support system, breast/bottle feeding, and child's health. EPDS scores were collected to calculate the prevalence of postpartum depression. Results: The EPDS was administered to 33 women at first year well-baby visits. Thirty-two were completed. Sixty-six percent of women had scores < 10 indicating no depression. Thirty-four percent reported scores of>=l 0 during the postpartum year …

Prevalence Of Depression In Gynecologic Outpatients At King Chulalongkorn Memorial Hospital, C. Roomruangwong, S. Hemrungrojn, S. Tangwongchai

Chulalongkorn Medical Journal

No abstract provided.

Depression: Relationships To Sleep Paralysis And Other Sleep Disturbances In A Community Sample, Mariana Szklo-Coxe, Terry Young, Laurel Finn, Emmanuel Mignot

Community & Environmental Health Faculty Publications

Sleep disturbances are important correlates of depression, with epidemiologic research heretofore focused on insomnia and sleepiness. This epidemiologic study’s aim was to investigate, in a community sample, depression’s relationships to other sleep disturbances: sleep paralysis (SP), hypnagogic/hypnopompic hallucinations (HH), cataplexy – considered rapid eye movement-related disturbances – and automatic behavior (AB). Although typical of narcolepsy, these disturbances are prevalent, albeit under-studied, in the population. Cross-sectional analyses (1998–2002), based on Wisconsin Sleep Cohort Study population-based data from 866 participants (mean age 54, 53% male), examined: depression (Zung Self-Rating Depression Scale), trait anxiety (Spielberger State-Trait Anxiety Inventory, STAI-T ≥ 75th percentile), and …

Bullying, Depression, And Suicidality In Adolescents, Anat Brunstein-Klomek, Frank Marrocco, Marjorie Kleinman, Irvin Sam Schonfeld, Madelyn S. Gould

Publications and Research

Objective: To assess the association between bullying behavior and depression, suicidal ideation, and suicide attempts among adolescents. Method: A self-report survey was completed by 9th- through 12th-grade students (n = 2342) in six New York State high schools from 2002 through 2004. Regression analyses were conducted to examine the association between being victimized and bullying others with depression, ideation, and attempts. Results: Approximately 9% of the sample reported being victimized frequently, and 13% reported bullying others frequently. Frequent exposure to victimization or bullying others was related to high risks of depression, ideation, and suicide attempts compared with adolescents not involved …

Peer Victimization, Depression, And Suicidality In Adolescents, Anat Brunstein Klomek, Frank Marrocco, Marjorie Kleinman, Irvin Sam Schonfeld, Madelyn S. Gould

Publications and Research

Objective: To assess the association between bullying behavior and depression, suicidal ideation, and suicide attempts among adolescents. Method: A self-report survey was completed by 9th- through 12th-grade students (n = 2342) in six New York State high schools from 2002 through 2004. Regression analyses were conducted to examine the association between being victimized and bullying others with depression, ideation, and attempts. Results: Approximately 9% of the sample reported being victimized frequently, and 13% reported bullyingothers frequently. Frequent exposure to victimization or bullying others was related to high risks of depression, ideation, and suicide attempts compared …