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Full-Text Articles in Medicine and Health Sciences

Influence Of Patient Characteristics On Perceived Risks And Willingness To Take A Proposed Anti-Rheumatic Drug, Richard W. Martin, Kelsey Mccallops, Andrew J. Head, Aaron T. Eggebeen Jan 2013

Influence Of Patient Characteristics On Perceived Risks And Willingness To Take A Proposed Anti-Rheumatic Drug, Richard W. Martin, Kelsey Mccallops, Andrew J. Head, Aaron T. Eggebeen

University Faculty Publications and Creative Works

The causes of the underutilization of disease modifying anti-rheumatic drugs (DMARDS) for rheumatoid arthritis (RA) are not fully known, but may in part, relate to individual patient factors including risk perception. Our objective was to identify the determinants of risk perception (RP) in RA patients and predictors of their willingness to take a proposed DMARD (DMARD willingness). Methods. A cross-sectional mail survey of RA patients in a community rheumatology practice. Patients were presented a hypothetical decision scenario where they were asked to consider switching DMARDs. They evaluated how risky the proposed medication was and how likely they would be to …


Does The Use Of Varenicline For Smoking-Cessation Therapy Create Or Increase Depression In Patients Without Existing Depressive Illness?, Brett R. Brown Jan 2013

Does The Use Of Varenicline For Smoking-Cessation Therapy Create Or Increase Depression In Patients Without Existing Depressive Illness?, Brett R. Brown

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of varenicline for smoking-cessation therapy creates or increases depression in patients without existing depressive illness.

STUDY DESIGN: Review of two randomized controlled trials published in 2011 and one observational cohort study published in 2009, all English language.
DATA SOURCES: Two randomized, double-blind, controlled clinical trials comparing varenicline to placebo in smoking cessation, and one observational cohort study comparing varenicline use within subjects. All articles were found using PubMed and EBSCO.

OUTCOMES MEASURED: Changes in depression was evaluated using the MontgomeryÅsberg Depression Rating Scale …


Anxiety, Depression, Social Phobia, And Quality Of Life In Turkish Patients With Acne And Their Relationships With The Severity Of Acne, Ahmet Öztürk, Erdem Deveci̇, Erman Bağcioğlu, Fi̇gen Atalay, Zehra Serdar Jan 2013

Anxiety, Depression, Social Phobia, And Quality Of Life In Turkish Patients With Acne And Their Relationships With The Severity Of Acne, Ahmet Öztürk, Erdem Deveci̇, Erman Bağcioğlu, Fi̇gen Atalay, Zehra Serdar

Turkish Journal of Medical Sciences

To investigate the psychiatric characteristics of acne vulgaris and the effects of the disease on quality of life. Materials and methods: We included 70 acne patients and 50 healthy controls. The Structured Clinical Interview for DSM-IV Axis I Disorders, Hospital Anxiety and Depression Scale, Liebowitz Social Anxiety Scale, Quality of Life Scale Short Form, and Acne Quality of Life Questionnaire were applied. Results: Anxiety and depression scores of the acne patients were significantly higher than those of the control group. In patients with acne, significantly higher levels of social anxiety were detected. Social anxiety levels of severe acne cases were …


Adolescent Depression Education Program For Middle School Nurses: A Feasibility Study, Teresa Carnevale Jan 2013

Adolescent Depression Education Program For Middle School Nurses: A Feasibility Study, Teresa Carnevale

MUSC Theses and Dissertations

While healthcare providers have increased depression screening of adolescents during preventive care, an enormous number of adolescents do not have regular contact with healthcare providers and, therefore, do not get screened. Nationwide screenings by school nurses would be an ideal way to capture students not seen by healthcare providers; however, this screening is not required and therefore does not occur. The purpose of this dissertation is to describe the three-step process by which the feasibility of using school nurses to identify and screen for adolescent depression (AD) was explored. In a pre-dissertation study, school nurses reported they lacked knowledge, time, …


Prevalence And Factors Associated With Depression Among Patients With Epilepsy In A Kenyan Tertiary Care Hospital, Nduku Kiko Jan 2013

Prevalence And Factors Associated With Depression Among Patients With Epilepsy In A Kenyan Tertiary Care Hospital, Nduku Kiko

Master of Medicine in Internal Medicine

Aim: To determine the prevalence and factors associated with depression in patients with epilepsy at Aga Khan University Hospital Nairobi. Design: Cross-sectional Survey Background: Depression is a recognized common co-morbidity of epilepsy that often goes untreated and has great impact on quality of life of patients and management of patients with epilepsy. Patients and Setting: Patients with epilepsy on follow up at the Aga Khan University Hospital were evaluated for presence and factors associated with depression. Methodology: The study recruited eligible patients with epilepsy who were on follow up in the neurology clinic. Beck Depression Inventory was administered to evaluate …


Depression And Hopelessness In Secondary And Higher Education Students, Ali Haydar Şar Jan 2013

Depression And Hopelessness In Secondary And Higher Education Students, Ali Haydar Şar

Khazar Journal of Humanities and Social Sciences

Depression and hopelessness are emotional problems which should be taken into consideration for secondary and higher education students in terms of development and education. In the research, it was tried to determine if depression and hopelessness vary according to education grades, gender and different departments. Beck Depression Scale and Beck Hopelessness Scale were applied to 1050 students in order to collect data in the research. According to obtained results, it was concluded that secondary level students have higher depression and hopelessness scale than higher education students; girls have higher depression levels than boys and boys have higher hopelessness levels than …


Predictors Of Treatments Acceptable To Patients For Late-Life Depression, Gerald J. Jogerst, Shimin Zheng, Erik Vanderlip Jan 2013

Predictors Of Treatments Acceptable To Patients For Late-Life Depression, Gerald J. Jogerst, Shimin Zheng, Erik Vanderlip

ETSU Faculty Works

Objectives. Describe older patients’ perceptions about depression and characteristics associated with acceptance of treatments. Design. Cross-sectional study. Setting. Three primary care clinics in Iowa. Participants. Consecutive sample of 529 primary care patients. Measurements. Depression screening tool (a 9-item patient health questionnaire [PHQ-9]) and questionnaire including sociodemographic data, patient attitudes about depression, and acceptability of different treatments. Results. Mean age was 71.9 years (range 60–93 years), 314 (59%) female. Among the 529 participants, 93 (17.5%) had history of depression and 60 (11.3%) had PHQ-9 scores of 10 or greater. Participants believed depression is a disease for which they would use medication …


Factors Related To Depression In Elderly Monks In Bangkok Metropolis, T Sriwilas, N. Thavichachat Jan 2013

Factors Related To Depression In Elderly Monks In Bangkok Metropolis, T Sriwilas, N. Thavichachat

Chulalongkorn Medical Journal

Background : Depression is a significant mental health problem in the elderly. Its impacts are physical, psychological, emotional and social. Depression can also be found in elderly monks. The study of depression and related factors may help decrease depression in elderly monks. Objective : To examine the depression and associated factors among elderly monks in Bangkok Metropolis. Design : A cross – sectional descriptive study. Setting : Buddhist monasteries in Bangkok Metropolis. Materials and Methods : The data were collected from 214 elderly monks in Bangkok Metropolis. They were selected by Multi-stage Cluster Sampling to respond to a questionnaire. The …


Risk Perception In Cardiovascular Disease, Michelle Ellen Block Jan 2013

Risk Perception In Cardiovascular Disease, Michelle Ellen Block

Dissertations

Cardiovascular disease (CVD) remains among the leading causes of death in the United States despite widespread knowledge about risk factors as well as effective primary prevention strategies. Risk perception is a complex phenomenon that plays an important role in how persons view disease and ultimately how they make health behavior choices. This study is supported by the knowledge that few studies have examined how persons perceive cardiovascular risk or the variables thought to contribute to the formation of risk perception.

Purpose: The purpose of this study was to examine how accurately persons perceive personal risk for cardiovascular disease and identify …


Is Pramipexole Safe And Effective In Reducing Depressive Symptoms In Patients With Mild To Moderate Parkinson’S Disease And Depression?, Corinne J. Kern Jan 2013

Is Pramipexole Safe And Effective In Reducing Depressive Symptoms In Patients With Mild To Moderate Parkinson’S Disease And Depression?, Corinne J. Kern

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not pramipexole (Mirapex) is a safe and effective drug to treat depression in patients with mild to moderate Parkinson’s Disease (PD).

STUDY DESIGN: Review of three English language primary randomized controlled trials and one randomized prospective, observational study published between 2003-2010.

DATA SOURCES: Three randomized controlled trials and one randomized prospective, observational study comparing the efficacy of pramipexole to placebo, sertraline (an SSRI) and other dopamine agonists (pergolide) in the treatment of PD related depression symptoms were found using PubMed.

OUTCOME(S) MEASURED: Each of the …


Is The Use Of Animal Assisted Therapy/Activity Effective In Improving Quality Of Life Through Self-Efficacy, Self-Perceived Health, Sense Of Coherence And Mood?, Kendra B. Keene Jan 2013

Is The Use Of Animal Assisted Therapy/Activity Effective In Improving Quality Of Life Through Self-Efficacy, Self-Perceived Health, Sense Of Coherence And Mood?, Kendra B. Keene

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of Animal Assisted Therapy/Activity is effective in improving quality of life through self-efficacy, self-perceived health, sense of coherence and mood.

STUDY DESIGN: Review of three English language randomized control trials, two published in 2008, and one published in 2009.

DATA SOURCES: Three randomized, controlled trials comparing Animal Assisted Therapy/Activity to restricted or absent animal contact or alternative control therapy were found using PubMed Health and Cochrane Systematic Reviews.

OUTCOMES MEASURED: Depression measured via BDI (Beck Depression Inventory), Anxiety measured via BAI (Beck Anxiety …


Does Laughter Therapy Improve Symptoms Of Depression Among The Elderly Population?, Audrey L. Shaw Jan 2013

Does Laughter Therapy Improve Symptoms Of Depression Among The Elderly Population?, Audrey L. Shaw

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or
not laughter therapy improves symptoms of depression among the elderly population.

STUDY DESIGN: A review of three studies written in the English language published between 2007 and 2011.

DATA SOURCES: Two randomized controlled trials and one pilot study comparing the effect of laughter therapy on depression were found using PubMed, Medline, OVID, and Cochrane databases.

OUTOMES MEASURED: Outcomes measured in the studies included depression, quality of life, and life satisfaction.

RESULTS: Laughter therapy was shown to be beneficial as both an independent …


Is Hypnotherapy An Effective Treatment For Depression?, Simone Youssef Jan 2013

Is Hypnotherapy An Effective Treatment For Depression?, Simone Youssef

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this EBM paper is to determine whether or not hypnotherapy is an effective treatment for depression.

STUDY DESIGN: Review of two English language randomized controlled trials and one case study published in 2007, 2009, and 2010.

DATA SOURCES: Two randomized controlled trials and one case study reviewing the effectiveness of hypnotherapy on depression were found using PubMed, Medline, and CINAHL.

OUTCOMES MEASURED: Depression was measured through the Beck Depression Inventory (BDI- II), which is a 21-question multiple choice self-report inventory based on scores of 0-63, with higher scores signifying more severe depressive …


Does Breastfeeding Offer Protection Against Maternal Depressive Symptomatology? A Prospective Study From Pregnancy To 2 Years After Birth, Jennifer Hahn-Holbrook, Martie G. Haselton, Christine Dunkel Schetter, Laura M. Glynn Jan 2013

Does Breastfeeding Offer Protection Against Maternal Depressive Symptomatology? A Prospective Study From Pregnancy To 2 Years After Birth, Jennifer Hahn-Holbrook, Martie G. Haselton, Christine Dunkel Schetter, Laura M. Glynn

Psychology Faculty Articles and Research

Depression is the leading cause of disability in women (Nobel 2005) and is the most prevalent of all childbearing-related illnesses, affecting approximately 13% of women worldwide within the first 12 [...] Mothers who breastfeed typically exhibit lower levels of depressive symptomatology than mothers who do not. However, very few studies have investigated the directionality of this relationship. Of the prospective studies published, all but one focus exclusively on whether maternal depression reduces rates of subsequent breastfeeding. This study again examines this relationship, but also the reverse--that breastfeeding might predict lower levels of later depression. Using multilevel modeling, we investigated the …


Association Between Concomitant Use Of Bisphosphonates And Serotonin Reuptake Inhibitors And Increased Risk Of Osteoporotic-Related Fractures: Among Community-Dwelling Postmenopausal Women, Abner Nyandege Jan 2013

Association Between Concomitant Use Of Bisphosphonates And Serotonin Reuptake Inhibitors And Increased Risk Of Osteoporotic-Related Fractures: Among Community-Dwelling Postmenopausal Women, Abner Nyandege

Theses and Dissertations

Osteoporosis and depression are prevalent among older postmenopausal women 65 years or older. Bisphosphonates (BPs) and selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs) are commonly used medications to treat these conditions. Inhibitory effects of BPs on osteoclasts are responsible for the reduction in fracture risk. SSRIs, however, are associated with increased fracture risk through decreasing osteoblasts and increasing osteoclastic activity. These effects of SSRIs could attenuate the beneficial effects of BPs. This dissertation describes the concomitant use of BPs and SSRIs among postmeopausa women and reports findings from examining the association between concomitant use of BPs …


Evaluation Of Depression Screening Practices For College Women In A Primary Care University Health Clinic, Sarah E. Lester Jan 2013

Evaluation Of Depression Screening Practices For College Women In A Primary Care University Health Clinic, Sarah E. Lester

DNP Projects

Mental disorders, including depression, are increasing in frequency and intensity in the college student population. College-aged women appear to be particularly vulnerable to depression. Primary care providers play an important role in addressing this issue, as they are the principal health care contacts for more than 50% of patients with mental illnesses. Guidelines from the 2009 United States Preventative Services Task Force recommend screening all adults (age 18+) for depression in primary care when depression care supports are in place. However, current screening rates for depression in the primary care setting from are estimated at only 1.6 to 3.3% (United …


Gene X Environment Effects Of Serotonin Transporter, Dopamine Receptor D4, And Monoamine Oxidase A Genes With Contextual And Parenting Risk Factors On Symptoms Of Oppositional Defiant Disorder, Anxiety, And Depression In A Community Sample Of 4-Year-Old Children, John V. Lavigne, Laura B.K. Herzing, Edwin H. Cook, Susan A. Lebailly, Karen R. Gouze, Joyce Hopkins, Fred B. Bryant Jan 2013

Gene X Environment Effects Of Serotonin Transporter, Dopamine Receptor D4, And Monoamine Oxidase A Genes With Contextual And Parenting Risk Factors On Symptoms Of Oppositional Defiant Disorder, Anxiety, And Depression In A Community Sample Of 4-Year-Old Children, John V. Lavigne, Laura B.K. Herzing, Edwin H. Cook, Susan A. Lebailly, Karen R. Gouze, Joyce Hopkins, Fred B. Bryant

Psychology: Faculty Publications and Other Works

Genetic factors can play a role in the multiple level of analyses approach to understanding the development of child psychology. The present study examined gene-environment correlations and Gene x Environment interactions for polymorphisms of three target genes, the serotonin transporter gene, the D4 dopamine reactor gene, and the monoamine oxidase A gene in relation to symptoms of anxiety, depression, and oppositional behavior. Saliva samples were collected from 175 non-Hispanic White, 4-year-old children. Psychosocial risk factors included socioeconomic status, life stress, caretaker depression, parental support, hostility, and scaffolding skills. In comparison with the short forms (s/s, s/l) of the serotonin transporter …


Conceptualizing The Use Of Cognitive Interventions Among Persons With Intellectual Disabilities Who Experience Depression, Abdoulaye Diallo, Shawn P. Saladin, Darlene A.G. Groomes, Jerome Fischer, Sandra Hansmann Jan 2013

Conceptualizing The Use Of Cognitive Interventions Among Persons With Intellectual Disabilities Who Experience Depression, Abdoulaye Diallo, Shawn P. Saladin, Darlene A.G. Groomes, Jerome Fischer, Sandra Hansmann

School of Rehabilitation Services & Counseling Faculty Publications

Depression can affect the lives of all persons and can have especially profound implications on those with cognitive limitations; however, depression need not be an insurmountable roadblock to employment for persons with intellectual disabilities. Cognitive interventions - such as life story approach, socio-cognitive, and rational emotive behavior therapy-can be effective for litigating problems with depression among those with cognitive limitation including employment-related barriers due to depression. This article reviews how counselors can use cognitive interventions' behavioral and cognitive components to assist those with intellectual disabilities with depression.


Race/Ethnicity, Subjective And Objective Sleep Quality, Physical And Psychological Symptoms In Breast Cancer Survivors, Pinky H. Budhrani Jan 2013

Race/Ethnicity, Subjective And Objective Sleep Quality, Physical And Psychological Symptoms In Breast Cancer Survivors, Pinky H. Budhrani

USF Tampa Graduate Theses and Dissertations

Breast cancer is a major health problem and comprises the largest population of cancer survivors in the United States, estimated at 2.9 million women, accounting for 22% of all cancer survivors (National Cancer Institute, 2013). The advances in breast cancer screening, diagnosis and treatment has increased the importance of survivorship needs. A major concern among breast cancer survivors (BCS) is sleep disturbances. This study used an innovative approach to examine ethnic and racial disparities in sleep disturbances present in BCS. In addition, this study also explored sleep disturbances across different races/ethnicities. This study was a secondary data analysis of baseline …


Relationship Between Dysphoric Moods, Risk-Taking Behaviors, And Toxoplasma Gondii Antibody Titers In Female Veterans, Allyson Radford Duffy Jan 2013

Relationship Between Dysphoric Moods, Risk-Taking Behaviors, And Toxoplasma Gondii Antibody Titers In Female Veterans, Allyson Radford Duffy

USF Tampa Graduate Theses and Dissertations

The number of female veterans is increasing daily. Previous research conducted on veterans has focused primarily on males or with small samples of females. Depression and suicidality are becoming increasingly evident in returning veterans. Toxoplasma gondii is an intracellular parasite that is common in the Middle East and has been reported to cause changes in personality and behavior.

The purpose of the current study was to examine relationships between T. gondii antibody titer and socioeconomic variables, dysphoric moods, and risk-taking behaviors in a sample of 70 female veterans. Blood samples were collected and analyzed for T. gondii antibody titer and …


The Strong Black Woman, Depression, And Emotional Eating, Michelle Renee Offutt Jan 2013

The Strong Black Woman, Depression, And Emotional Eating, Michelle Renee Offutt

USF Tampa Graduate Theses and Dissertations

Abstract

Eighty percent of all black women are overweight or obese which can lead to greatly increased morbidity and mortality, increasing healthcare costs and loss of healthy years of life. While multiple factors may contribute to obesity in black women, the cultural persona of the Strong Black Woman (SBW), an ideology that promotes unflagging toughness and denial of self-needs, may be the basis for behaviors that contribute to steady state obesity in this group. The purpose of this study was to investigate the relationships between the SBW persona, depression, and emotional eating.

Two predominately black churches in Florida were approached …


An Evaluation Of Social Capital's Effect On Depression Among Adolescents, Ezechukwu Awgu Dec 2012

An Evaluation Of Social Capital's Effect On Depression Among Adolescents, Ezechukwu Awgu

Dissertations

Mental illness has been described as a “global burden of disease,” and depression accounts for a large part of the burden (Aslund, Starrin, Nilsson, 2010). In 2009, 35.7 percent of the adolescent population in the United States who reported past-year symptoms of a major depressive episode, for example, feelings of sadness, discouragement, loss of feelings of self-worth, and loss of interest in social activities, also used illicit drugs including marijuana, inhalants, hallucinogens, cocaine, heroin, and prescription-type psychotherapeutics for non-medical purposes (SAMHSA, 2009, APA, 1994). Additionally, substance abuse due to alcoholism was among the major causes of death for adolescents aged …


Determinan Keluhan Muskuloskeletal Pada Tenaga Kerja Wanita, Andi Zulkifli Abdullah, A. Arsunan Arsin, Muhammad Yahya Nov 2012

Determinan Keluhan Muskuloskeletal Pada Tenaga Kerja Wanita, Andi Zulkifli Abdullah, A. Arsunan Arsin, Muhammad Yahya

Kesmas

Insomnia merupakan gangguan tidur yang paling sering ditemukan pada lanjut usia (lansia) dengan prevalensi sekitar 67%. Penelitian ini bertujuan untuk menilai hubungan antara kecemasan, depresi, dukungan keluarga, dan kondisi lingkungan dengan kejadian insomnia pada lansia di Panti Sosial Tresna Werdha Gau Mabaji Kabupaten Gowa. Penelitian ini menggunakan desain studi observasional dengan rancangan cross sectional dan metode exhausive sampling. Data dianalisis dengan uji chi square, koefisien phi (f) dengan a = 0,05. Sebanyak 96 lansia penghuni panti memenuhi kriteria penelitian. Uji chi square menunjukkan bahwa terdapat hubungan antara kecemasan (nilai p = 0,014; f = 0,251), depresi (nilai p = 0,019; …


Factors Associated With Quality Of Life Of Breast Cancer Patients, S Thanasilp, M. Wongpromchai Nov 2012

Factors Associated With Quality Of Life Of Breast Cancer Patients, S Thanasilp, M. Wongpromchai

Chulalongkorn Medical Journal

Background : To improve the quality of life (QOL) of breast cancer patients is an important issue for nursing staff. Therefore, understanding the associated factors with QOL is a crucial knowledge for developing nursing intervention. Objective : To examine the associated factors with QOL and the effected factors on the QOL of breast cancer patients. Design : A cross-sectional descriptive design. Patients : One hundred and fifty female patients with breast cancer receiving chemotherapy. Material and Method : The participants were asked to respond to a set of seven questionnaires: The Personal Data Form, Piper Fatigue Scale, Pain Scale, Depression …


The Long-Term Impact Of Physical And Emotional Trauma: The Station Nightclub Fire, Jeffrey C. Schneider, Nhi-Ha T. Trinh, Elizabeth Selleck, Felipe Fregni, Sara S. Salles, Colleen M. Ryan, Joel Stein Oct 2012

The Long-Term Impact Of Physical And Emotional Trauma: The Station Nightclub Fire, Jeffrey C. Schneider, Nhi-Ha T. Trinh, Elizabeth Selleck, Felipe Fregni, Sara S. Salles, Colleen M. Ryan, Joel Stein

Physical Medicine and Rehabilitation Faculty Publications

BACKGROUND: Survivors of physical and emotional trauma experience enduring occupational, psychological and quality of life impairments. Examining survivors from a large fire provides a unique opportunity to distinguish the impact of physical and emotional trauma on long-term outcomes. The objective is to detail the multi-dimensional long-term effects of a large fire on its survivor population and assess differences in outcomes between survivors with and without physical injury.

METHODS AND FINDINGS: This is a survey-based cross-sectional study of survivors of The Station fire on February 20, 2003. The relationships between functional outcomes and physical injury were evaluated with multivariate regression models …


On The Genetic And Environmental Associations Between Body Composition, Depression Symptoms And Smoking Behavior., Roseann Peterson Oct 2012

On The Genetic And Environmental Associations Between Body Composition, Depression Symptoms And Smoking Behavior., Roseann Peterson

Theses and Dissertations

Obesity is a serious public health crisis and recent estimates of its incidence are the highest in United States history, with 35% and 17% of American adults and children affected, respectively. The clinical definition of adult obesity is operationalized as a body mass index (BMI) greater than 30 kg/m2. Although the prevalence of common obesity has increased dramatically over the past 30 years–largely thought to be due to changes in the environment, such as high calorie diets and sedentary lifestyles—twin and family studies have shown consistently that relative body weight is under considerable genetic influence in both children and adults, …


Drug–Drug Conditioning Between Citalopram And Haloperidol Or Olanzapine In A Conditioned Avoidance Response Model: Implications For Polypharmacy In Schizophrenia, Nathan L. Sparkman, Ming Li Oct 2012

Drug–Drug Conditioning Between Citalopram And Haloperidol Or Olanzapine In A Conditioned Avoidance Response Model: Implications For Polypharmacy In Schizophrenia, Nathan L. Sparkman, Ming Li

Department of Psychology: Faculty Publications

Patients with schizophrenia often have anxiety and depression, and thus are treated with multiple psychotherapeutic medications. This practice of polypharmacy increases the possibility for drug–drug interactions. However, the pharmacological and behavioral mechanisms underlying drug–drug interactions in schizophrenia remain poorly understood. In the present study, we adopted a preclinical approach and examined a less known behavioral mechanism, drug–drug conditioning (DDC) between haloperidol (a typical antipsychotic) or olanzapine (atypical antipsychotic) and citalopram (a selective serotonin reuptake inhibitor). A rat two-way conditioned avoidance response paradigm was used to measure antipsychotic activity and determine how DDC may alter the antipsychotic efficacy in this model. …


Psychosocial Vulnerabilities To Depression After Acute Coronary Syndrome: The Pivotal Role Of Rumination In Predicting And Maintaining Depression, Ellen-Ge Denton, Nina Rieckmann, Karina W. Davidson, William F. Chaplin Aug 2012

Psychosocial Vulnerabilities To Depression After Acute Coronary Syndrome: The Pivotal Role Of Rumination In Predicting And Maintaining Depression, Ellen-Ge Denton, Nina Rieckmann, Karina W. Davidson, William F. Chaplin

Publications and Research

Psychosocial vulnerabilities may predispose individuals to develop depression after a significant life stressor, such as an acute coronary syndrome (ACS).The aims are (1) to examine the interrelations among vulnerabilities, and their relation with changes in depressive symptoms 3 months after ACS, (2) to prospectively assess whether rumination interacts with other vulnerabilities as a predictor of later depressive symptoms, and (3) to examine how these relations differ between post-ACS patients who meet diagnostic criteria for depression at baseline versus patients who do not. Within 1week after hospitalization for ACS, and again after 3 months, 387 patients (41% female, 79.6% white, mean …


Oncolog, Volume 57, Number 08, August 2012, Amelia Scholtz, Dawn Chalaire Aug 2012

Oncolog, Volume 57, Number 08, August 2012, Amelia Scholtz, Dawn Chalaire

OncoLog MD Anderson's Report to Physicians (All issues) Archives

  • Preoperative Chemotherapy Offers Best Outcomes for Patients with Rare Bladder Cancer: A combination of neoadjuvant chemotherapy and surgery provides patients who have small-cell urothelial cancer (SCUC) with much longer survival times than does initial surgery, the previous standard treatment
  • Addressing Psychological Concerns for Cancer Patients: Despite advances in cancer treatment over the past several years, for many people, a diagnosis of cancer can still feel like a death sentence. The added stress leads to psychological problems for many patterns
  • INBRIEF: New Antibody Treatment Produces Responses in Patient with Advanced Cancer/Accelerated Partial-Breast Brachytherapy Associated with Decreased Long-Term Breast Preservation and Increased …


Primary Care Behavioral Health Consultation Reduces Depression Levels Among Mood-Disordered Patients, Bill Mcfeature, Thomas W. Pierce Jul 2012

Primary Care Behavioral Health Consultation Reduces Depression Levels Among Mood-Disordered Patients, Bill Mcfeature, Thomas W. Pierce

Journal of Health Disparities Research and Practice

The purpose of this study was to examine the effects of behavioral health consultative services on levels of depressive symptoms in patients diagnosed with a mood disorder. Two-hundred fifty-one patients with a form of mood disorder completed the PHQ-9 screening tool for depression both before and after a treatment period lasting an average of three months, during which patients received behavioral health consultation services. Results showed that 49.8% of patients participating in this integrated behavioral health care program experienced improvements of at least 50% in PHQ-9 scores from pre- to post-test. Improvements in PHQ-9 scores of at least a five …