Medicine and Health Sciences Commons^™

Efficacy Of Transcranial Magnetic Stimulation In Treatment-Resistant Depression, Kemal Akpinar, Nalan Kalkan Oğuzhanoğlu, Tuğçe Toker Uğurlu

Turkish Journal of Medical Sciences

Background/aim: The use of Transcranial Magnetic Stimulation (TMS) in the add-on treatment of patients with treatment-resistant depression (TRD) is becoming more common. This study aims to investigate the efficacy of TMS on depression and accompanying anxiety symptoms among patients with TRD. Materials and methods: The current study was conducted with 38 patients diagnosed with TRD. The patients were randomly divided into two groups and received 20 sessions of high-frequency (10Hz) TMS and 20 sessions of sham TMS to the left dorsolateral prefrontal cortex in a double-blind and cross-over fashion without a change in their pharmacotherapy. In the clinical evaluation, Hamilton …

Love Outside Margins: Mental Health And Marginalization In Intercultural And Monocultural Couples, Tara Masseratagah

Antioch University Dissertations & Theses

As the number of intercultural couples increases in North America, the impact of perceived marginalization of these relationships on the mental health of individuals is an area that requires continued clinical understanding. This quantitative study sought to explore how anxiety and depression levels in intercultural and monocultural couples are associated with levels of perceived marginalization. Qualitative follow-up questions were used to understand the varying reasons for marginalization and support between couples. One hundred twenty-four individual participants in romantic relationships took part in this study; of this, 64 were in monocultural relationships and 60 were in intercultural relationships. This study found …

“Om” Chanting And Its Impact On Selected Neuropsychological Functions: A Literature Overview, Suresh Kumar Thanneeru, Roshan F. Sutar, Vijendra Singh, Anuradha Kushwah, Saikat Das, Mahendra Atlani, Madhukar Mittal, Amit Agrawal

Manipal Journal of Medical Sciences

The "OM" mantra is one of the most sacred symbols in Indian culture, and Om chanting holds emotional, spiritual, and religious significance. The domain and spectrum of the impact of "Om" chanting include delta and theta brainwaves on EEG, overall EEG activity, asthma symptom control, quality of life, brain hemodynamics, and physiological and psychological effects of "Om" chanting and singing. It also plays a role in the management of major depressive disorder (MDD). "OM" listening or chanting activates the frontal lobe and supramarginal gyrus, promoting calmness, enhancing thinking processes, and improving memory. In the present review, we selectively examine articles …

Mental Health, Bullying, And Victimization Among Chinese Adolescents, Yang Wen, Xihe Zhu, Justin A. Haegele, Fangliang Yu

Human Movement Studies & Special Education Faculty Publications

The purpose of this study was to examine if adolescents who experience anxiety or depression have higher levels of reported bullying victimization or perpetration than those who do not. Based on the existing research, we hypothesized that those who experienced moderate or severe depression and anxiety would have higher rates of bullying victimization and perpetration when compared to those who experienced mild or no depression. This study used an observational design, and data were collected from a convenience sample of adolescents in a large regional high school in an Eastern province of China. The final sample included 1481 adolescents aged …

Interactions Of International Pilots' Stress, Fatigue, Symptoms Of Depression, Anxiety, Common Mental Disorders And Wellbeing, Marion Venus, Martin Grosse Holtforth

International Journal of Aviation, Aeronautics, and Aerospace

Objective

This study Investigates more dimensions than previous studies simultaneously: pilots’ duty rosters, stress, sleep difficulties, fatigue levels, wellbeing, symptoms of depression, anxiety, and common mental disorders (CMD), and how they are interrelated.

Background

Several scientific studies have confirmed that fatigue can pose a significant risk to flight safety. Other studies reported positive depression screening results for more pilots, compared with the general population.

Method

A cross-sectional online survey was completed by 406 international pilots, who reported their duty rosters of the last two months. Pilots also self-assessed their stress-levels, sleep problems, fatigue, wellbeing, and mental health.

Results

Although pilots …

Machine Learning Techniques For Predicting Depression And Anxiety In Pregnant And Postpartum Women During The Covid-19 Pandemic: A Cross-Sectional Regional Study, Radwan Qasrawi, Malak Amro, Stephanny Vicunapolo, Diala Abu Al-Halawa, Hazem Agha, Rania Abu Seir, Maha Hoteit, Reem Hoteit, Sabika Allehdan, Nouf Behzad, Khlood Bookari, Majid Alkhalaf, Haleama Al-Sabbah, Eman Badran, Reema Tayyem

All Works

Background: Maternal depression and anxiety are significant public health concerns that play an important role in the health and well-being of mothers and children. The COVID-19 pandemic, the consequential lockdowns and related safety restrictions worldwide negatively affected the mental health of pregnant and postpartum women. Methods: This regional study aimed to develop a machine learning (ML) model for the prediction of maternal depression and anxiety. The study used a dataset collected from five Arab countries during the COVID-19 pandemic between July to December 2020. The population sample included 3569 women (1939 pregnant and 1630 postpartum) from five countries (Jordan, Palestine, …

The Psychological Impact Of Isolation On Hospitalised Patients With Covid-19 Infection In The Uae, Nahida Nayaz Ahmed, Nirmin F. Juber, Reem Alkaabi, Fatema Alshehhi, Mohamed Alobeidli, Ahlam Salem, Alaa Galadari, Shamil Wanigaratne, Amar Ahmad

All Works

Infection prevention and control measures for COVID-19 may include immediate admission to an isolation facility for the infected. However, the mental health impact of this isolation worldwide is not fully documented. This study aims to contribute to global data on the psychological impact of COVID-19 and to be the first study to assess psychological distress among hospitalised patients with COVID-19 in the UAE. Using a cross-sectional study design on 132 hospitalised patients, we found that 90% of participants scored within the normal levels for psychological distress. The length of stay was associated with higher levels of psychological distress and those …

Relación Entre La Depresión Y La Demencia [Relationship Between Depression And Dementia], Maria Del Pilar Santacruz-Ortega, Maria Fernanda Cobo-Charry, Silvia Mejia-Arango

School of Medicine Publications

La alta asociación entre la depresión y la demencia en el adulto mayor ha motivado a investigar la clase de relación que existe entre ellas. El objetivo de esta revisión narrativa fue describir la relación entre la depresión y la demencia, para lo que se revisaron las bases de datos Medline, Science Direct, Dialnet, Redalyc entre 2000 y 2021, con los descriptores verbales “demencia” AND “depresión” AND “relación” AND “adulto mayor” OUT “depresión de cuidadores” para ubicar los documentos candidatos y luego elegir la muestra final conformada por 67 artículos publicados, que fueron revisados por tres jueces para la selección. …

Vitamin D Level In Relation To Depression Symptoms During Adolescence, Reem Al-Sabah, Abdullah Al-Taiar, Lemia Shaban, Ahmed N. Albatineh, Reem Sharaf Alddin, Praveen K. Durgampudi

Community & Environmental Health Faculty Publications

BACKGROUND: This study aimed to investigate the association between 25-hydroxyvitamin D (25(OH)D) and depression symptoms among adolescents in Kuwait, a country with a high prevalence of vitamin D deficiency.

METHODS: A school based cross-sectional study was conducted on randomly selected 704 adolescents in middle schools. Data on depression symptoms were collected using the Children's Depression Inventory (CDI). Data on covariates were collected from the parents by self-administered questionnaire and from adolescents by face-to-face interview. Blood samples were analyzed in an accredited laboratory; and 25(OH)D was measured using liquid chromatography-tandem mass spectrometry.

RESULTS: Of 704 adolescents, 94 (13.35%; 95%CI:10.35-17.06%) had depression …

Validity And Reliability Of The Thai-Version Of Post Stroke Depression Scale (Psds-T), Kuankidnuttha Arunsri, Aurauma Chutinet, Sookjareon Tangwongchai

Chulalongkorn Medical Journal

Background: Currently, there has been limited effective and practical instruments for screening post-stroke depression (PSD) in Thailand. In 2014, Post-Stroke Depression Scale (PSDS) has been testified to be a valid and reliable self-rated questionnaire for evaluating Chinese patients with PSD. Objective: This study proposed to validate the Thai version of PSDS (PSDS-T) in Thai patients with acute ischemic stroke. Methods: The PSDS was translated into Thai language (PSDS-T). The validity and reliability were tested in 145 acute ischemic stroke patients. Subjects were consecutively recruited to complete PSDS-T; they were clinically evaluated for PSD using DSM-5 diagnosis of adjustment disorder with …

The Benefit Of Bdnf Modification In The Treatment Of Post-Stroke Depression, Christine Gordynskiy-Ageyev

Capstone Showcase

Neuroplasticity has been a rapidly expanding area of research, and its findings have elucidated the potential of taking advantage of some of its components for the treatment of various neural pathologies. Stroke is the most common cause of long-term disability, and it is a disease process that affects many people. There are many rehabilitation programs that seek to restore a patient’s motor and cognitive functions after stroke; if not fully, then at least partially. Unfortunately, mental health changes contribute in large part to the overall disability of a patient, but these changes are not always targeted in these programs. In …

Do Probiotics Decrease Depressive Symptoms In Patients With Low Mood?, Kaitlyn Talt

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine, “Do probiotics decrease depressive symptoms in patients with low mood?”

Study Design: A systematic review of three double blind, randomized control trials (RCTs) published between 2016 and 2019.

Data Sources: All three RCTs were found using PubMed and published in English in peer-reviewed journals. The articles were chosen based on their attention to patient-oriented evidence that matters (POEMS) and their relevance to the clinical question.

Outcome Measured: All three articles utilized either the Beck Depression Index (BDI) and/or the Depression Anxiety Stress Scale (DASS) to measure the severity of …

Interpersonal Psychotherapy For Depressed Adolescents: A Systematic Review Of Quantitative Studies Exploring Effectiveness, Concomitant Findings, And Mediating And Moderating Variables, Luke Rex

Theses and Dissertations

Depression is one of the leading causes of illness and disability among adolescents. According to the National Institute of Mental Health (2022), almost one-fifth of adolescents ages 12 to 17 years in the United States had at least one major depressive episode in 2020, representing 4.1 million people, and over half did not receive any treatment. An interpersonal approach to therapy for adolescents known as Interpersonal Psychotherapy for Depressed Adolescents (IPT-A), developed by Dr. Laura Mufson, has been regarded as having well-established efficacy in treating depressed adolescents. This systematic review of quantitative studies (without meta-analysis) was conducted to (a) examine …

Systematic Review Regarding The Use Of Mindfulness-Based Mobile Applications To Reduce Psychological Symptoms And Enhance Well-Being Among General And Clinical Population Adults: Benefits, Limitations And Future Directions, Brian Clawson

Theses and Dissertations

Mindfulness is now utilized throughout Western Society and is part of the growing behavioral health, self-help, and wellness movements. Mobile applications have become increasingly popular for a wide variety of uses related to physical health, mental health, and self-improvement. Therefore, mindfulness-based mobile applications have promise both as stand-alone tools for end-users seeking self-help resources and as clinician-recommended adjunctive tools to enhance the process and outcomes of professional therapy. This systematic review identified, reviewed, and synthesized the findings from studies (n = 29) concerning the impact of mindfulness-based mobile applications on specific aspects of psychological functioning in both the general population …

Increased Risk Of Major Depressive Disorder Following Tinnitus: A Population-Based Study, Herng-Ching Lin, Sudha Xirasagar Mbbs., Ph.D., Chia-Hui Wang, Yen-Fu Cheng, Tzong-Hann Yang

Publications

BACKGROUND AND PURPOSE: In this study, we aimed to evaluate the relationship between tinnitus and a subsequent diagnosis of major depressive disorder (MDD) by studying the incidence of both entities. DESIGN: A retrospective cohort study. METHODS: Data for this observational follow-up study were retrieved from the Taiwan's National Health Insurance Dataset. A total of 375,272 patients with newly diagnosed tinnitus (study group) were retrieved. The date of first diagnosis of tinnitus was assigned as their index date. Comparison patients were selected by propensity score matching (one per case, n = 375,272 controls) from the same dataset, with their index date …

Examining Ayahuasca Constituents At 5-Ht2a Receptors In Search Of Antidepressant Action, Jeremy D. Rolquin

Theses and Dissertations

Recently, it has been reported that ligands of the 5-HT_2A receptor can have drastic and fast-acting efficacy towards a number of different mental health disorders, such as depression and anxiety. A mixture of Amazonian plants calledayahuasca contains multiple compounds which have been shown to interact with the serotonergic system, and the 5-HT_2Areceptor in particular.

The structurally similar compounds (DMT, harmine, harmaline, and tetrahydroharmine) found in ayahuasca were examined for differences in their physiochemical properties that might contribute to their binding affinity for the 5-HT_2Areceptor. 3D Molecular modeling and docking studies of these compounds were …

The Relationship Between Social Media Use And Depression And Anxiety Symptoms During Covid-19, Tene'sha L. Crews, Christina Sheerin

Undergraduate Research Posters

The rise of the coronavirus (COVID-19) pandemic has caused a global surge in exposure to disaster and crisis-related media. Increases in poor mental health outcomes such as anxiety and depression, are associated with increased exposure to such media content (Abbas et al., 2021; Riehm et al., 2020; Zhao & Zhou, 2020). In recent years, social media has become one of the most widely used sources for news; approximately 48% of adult Americans receive their news from social media (Pew Research Center, 2021). During the COVID-19 pandemic, there has been an increase in social media use due to social distancing and …

Social Media Use And Mental Health: An Educational Intervention To Reduce Depression And Anxiety In Adolescents, Natalie Catlett

DNP Projects

Background: Most adolescents spend a great deal of their time using various social media platforms. However, excessive and maladaptive social media use is correlated with worsening symptoms of depression and anxiety among adolescents.

Objective: This project aimed to determine whether an educational intervention could help decrease overall time spent using social media and improve mood and mental health outcomes among adolescents with depression or anxiety disorders.

Methods: This was a quasi-experiment with a pretest and posttest design. An educational intervention about the relationship between social media use and symptoms of depression and anxiety among adolescents and strategies to minimize risk …

Promotion Of Early Recognition Of Depression To Improve Health Related Quality Of Life In Pediatric Oncology Patients, Jennifer Blankenship

DNP Projects

Background: Depression and anxiety are serious complications of cancer and deemed a challenging diagnosis due to the symptoms of depression mimicking common side effects of chemotherapy and radiation. Signs/symptoms frequently are underrecognized thus appropriate treatment is delayed, compromising the health-related quality of life (HRQOL) for pediatric oncology patients.

Purpose: Analyze existing physician and Advanced Practice Provider (APP) clinical practice regarding depression, via a pre- and post-survey and educational PowerPoint on the use of the Center for Epidemiological Studies Depression Scale for Children (CES-DC) to promote early recognition of depression.

Methods: A prospective, single-arm, study was completed in the Kentucky Children’s …

Association Between Rheumatoid Arthritis Severity And Mental Health In A Prevalent Cohort Of American Adults, 2013-2022, Nicole-Anne Ballesteros

Public Health Theses

Objective/Purpose: The severity of rheumatoid arthritis and its association with depression and anxiety among a prevalent cohort of American adults has been neither well-researched nor backed by real-world data. This investigation seeks to test the hypothesis that there is an association between disease severity and the aforementioned psychological conditions, both of which are commonly observed in patients with rheumatoid arthritis.

Methods: Real-world data from OM1 Inc.’s rheumatoid arthritis registry (2013-2022) was used for this analysis. Disease severity (low, medium, and high), categorized using disease activity scores, was the main exposure, while depression and anxiety were the study’s two primary outcomes. …

Putative Mechanisms Underlying The Antidepressant Actions Of Ketamine: A Review And Study Proposal, Tristan Reece

CMC Senior Theses

Major Depressive Disorder (MDD) is a highly debilitating and common psychiatric disorder that affects over 250 million people globally; it is among the most financially and emotionally burdensome illnesses in the world. Currently approved antidepressants are suboptimal in their efficacy and latency of therapeutic action. In contrast, single administrations of sub-anesthetic ketamine have been shown to rapidly alleviate depressive symptoms within hours, even in treatment-resistant patients. Ketamine is believed to exert these effects by increasing glutamatemediated neurotransmission and promoting rapid neurotrophic factor release, restoring the integrity of neural circuits that are compromised in depression. However, uncertainty surrounding its specific antidepressant …

Help-Seeking Behaviors For Depression Among Native Hawaiian Women In The Western Region Of The United States Mainland, Marlana Glover

Walden Dissertations and Doctoral Studies

Help-seeking for depression, as with other mental illnesses is contingent upon stigmas that one perceives. Although causes for depression differ among indigenous populations, native Hawaiians suffer from the Western acculturation and colonization of their homeland. With lack of trust in the U.S. healthcare system, many native Hawaiians are reluctant to seek help for depression. Furthermore, research has shown that most studies on native Hawaiians are conducted in their native environment when many Hawaiians relocate to the U.S. mainland. Because of the current depression crisis, it is critical to explore depression among native Hawaiians, particularly women on the mainland to see …

Health Educator Experience: Recommendations For Physical Activity For Mental Health In Women, Patricia Schneider

Walden Dissertations and Doctoral Studies

Mental health issues, specifically anxiety and depression, continue to be a public health crisis in the United States. Despite the established therapies of pharmacology and cognitive behavioral therapy, not all patients seek or find relief using these methods. Therefore, other treatment strategies need to be studied. The purpose of this basic qualitative study was to understand the experiences of health educators who use physical activity as a strategy for anxiety and depression management among middle-aged women as well as their own attitudes, norms, and perceived behavioral controls. The theory of planned behavior (TPB) was leveraged as the theoretical foundation for …

A Comparison Of The Magnitude Of The Mental Health Benefits Of Exercising Outdoors Vs Exercising Indoors: A Review, Greta M. Rueschmann

Graduate Theses/Dissertations

Many people in the United States suffer from poor mental health which can lead to suicide, self-harm, or negative effects on job performance and relationships. Not everyone can afford traditional therapy nor feels comfortable with it. With a greater emphasis placed on taking care of one’s mental health during the COVID-19 pandemic, there should also be a greater emphasis placed on finding alternative types of therapy that can be matched to individuals based on their personalities and preferences. One such alternative is outdoor exercise. This review was conducted to examine whether exercising or performing physical activity outdoors results in greater …

Depression And Anxiety Amongst College D1 Athletes, Jessica Radford

University of the Pacific Theses and Dissertations

College student-athletes are having an increasingly amount of mental health concerns recently at an alarming rate. Therefore, researchers should attempt to better understand how student-athletes can cope with their mental health problems to improve their mental and physical well-being. The researcher administered a questionnaire to 300 college students, 150 student-athletes and 150 non-athletes from the University of the Pacific using various modified scales examining emotional intelligence, depression, anxiety, coping strategies, intentions to seek help, self-stigma, public stigma, social network stigma, alcohol consumption, sleep deprivation, and communication competence. The data were analyzed to determine the severity of student-athletes’ mental health and …

The Effect Of Integrative Medicine Interventions On Patient Activation Measure, Rochelle F. Richards

All ETDs from UAB

Activated patients believe they have essential roles in achieving and maintaining their health. Patient activation is strongly related to improved clinical outcomes (Hibbard, 2017; Greene, 2013). The study’s primary purpose is to evaluate the use of Integrative Medicine Interventions (IMIs) and their relationship to patient activation levels; and to investigate the association between IMI protocols and patient activation levels on patient reported outcomes (PROs) for those with chronic diseases, specifically chronic fatigue and mental health-related conditions of anxiety and depression, using the principles of Integrative Medicine’s (IM) whole-person approach as the model of care in independent IM practices across the …

The Neighborhood Environment And Hispanic/Latino Health, Natalia I Heredia, Tianlin Xu, Minjae Lee, Lorna H Mcneill, Belinda M Reininger

Faculty, Staff and Student Publications

PURPOSE: Hispanic/Latino adults on the Texas-Mexico border have high rates of chronic disease. Neighborhoods can influence health, though there is a limited research on neighborhood environment and health in Hispanics/Latinos. The purpose of this study was to assess the relation of neighborhood environment with health variables in Hispanic/Latino adults, including physical activity [PA], depression, anxiety, and lab-assessed conditions (type 2 diabetes, metabolic syndrome, and chronic inflammation).

METHODS: Participants were randomly-selected from a Hispanic/Latino cohort on the Texas-Mexico border. Neighborhood environment, self-reported PA, anxiety, and depression were assessed through questionnaires. Laboratory values determined Type 2 diabetes, metabolic syndrome, and C-reactive protein …

An Examination Of The Relationship Between Fear Of Evaluation, Social Anxiety, And Depression, Michelle Ingraffia

Masters Theses

This study explores fear of negative evaluation (FNE) and fear of positive evaluation (FPE) across social anxiety and depression. The following assessment tools were used to measure fear of positive evaluation, fear of negative evaluation, social anxiety, and depression: Fear of Positive Evaluation Scale, Brief Fear of Negative Evaluation - Straightforward, Liebowitz Social Anxiety Scale – Self Report, The Center for Epidemiological Studies Depression Scale – Revised. A sample of two hundred and thirty-one participants completed forms online via Amazon Mechanical Turk. Social anxiety was correlated positively with both FNE and FPE; likewise, depression was correlated positively with both FNE …

Incidence Of Cancer, Depression, And Economic Burden Of Prescription Nsaids Among Older Adults With Osteoarthritis: Statistical And Machine Learning Approaches, Nazneen Fatima Mohammed Umer Shaikh

Graduate Theses, Dissertations, and Problem Reports (ETD)

Understanding the role of chronic inflammation among older adults is critical because of its implications on chronic inflammatory conditions as well as its interaction with anti-inflammatory medications. Osteoarthritis (OA) is a heterogeneous multi-faceted joint disease with multi-tissue involvement of varying severity, and increasing evidence demonstrates a key role of chronic inflammation in its pathogenesis. Approximately 30 million adults in the United States have OA, and it is reported that a large proportion (43%) of them are older than 65 years. OA is typically treated using non-steroidal anti-inflammatory drugs (NSAIDs) for minimizing pain and reducing inflammation. NSAIDs have consistently shown clinically …

Investigating The Influence Of Stress On Motivational Dysfunction In Male And Female Rodents, Emily Laine Errante

Graduate Research Theses & Dissertations

Motivational dysfunction is present in a variety of disorders, including major depressive disorder, schizophrenia, and Parkinsonism and can negatively impact social functioning, employment, and treatment response. Interestingly, outside stressors and stress hormones have been shown to contribute to depressive episodes in humans and depressive-like behaviors in rodents, including reducing motivated behaviors. Effort-related decision making procedures have been utilized in both humans and animals in order to examine motivational dysfunction, as it offers a subject a choice between high effort/reward and low effort/reward options, but little research has examined the effects of stress on effort-related decision making behaviors. Moreover, almost all …