Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

COVID-19

Discipline
Institution
Publication Year
Publication
Publication Type
File Type

Articles 5401 - 5430 of 7417

Full-Text Articles in Medicine and Health Sciences

Can Positive Mindsets Be Protective Against Stress And Isolation Experienced During The Covid-19 Pandemic? A Mixed Methods Approach To Understanding Emotional Health And Wellbeing Needs Of Perinatal Women, Jacqueline A. Davis, Lisa Y. Gibson, Natasha L. Bear, Amy L. Finlay-Jones, Jeneva L. Ohan, Desiree T. Silva, Susan L. Prescott Jan 2021

Can Positive Mindsets Be Protective Against Stress And Isolation Experienced During The Covid-19 Pandemic? A Mixed Methods Approach To Understanding Emotional Health And Wellbeing Needs Of Perinatal Women, Jacqueline A. Davis, Lisa Y. Gibson, Natasha L. Bear, Amy L. Finlay-Jones, Jeneva L. Ohan, Desiree T. Silva, Susan L. Prescott

Research outputs 2014 to 2021

The aim of this study was to explore the relationship between emotional health and well-being and support needs of perinatal women during the COVID-19 pandemic, and to understand their experiences and need for support. This is a potentially vulnerable group and a critical developmental phase for women and infants. A mixed methods design was used to collect quantitative and qualitative data that provided a robust insight into their unique needs. A total of 174 women who were either pregnant or post-birth participated. The main findings demonstrated that women in this cohort experienced varying levels of stress and isolation but also …


Active Learning Strategy For Covid-19 Annotated Dataset, Amril Nazir, Ricky Maulana Fajri Jan 2021

Active Learning Strategy For Covid-19 Annotated Dataset, Amril Nazir, Ricky Maulana Fajri

All Works

The efficient diagnosis of COVID-19 plays a key role in preventing its spread. Recently, many artificial intelligence techniques, such as the deep neural network approach, have been implemented to help efficient diagnosis of COVID-19. However, the accurate performance of deep learning depends on the tuning of many hyperparameters and a large amount of labeled data. This COVID-19 data bottleneck also leads to insufficient human resources for data labeling, which presents a challenging obstacle. In this paper, a novel discriminative batch-mode active learning (DS3) is proposed to allow faster and more effective COVID-19 data annotation. The framework specifically designed to suit …


Nutritional Aspects Related To Covid-19: A Bibliometric Analysis Using Scopus Database, Arti Muley Dr, Srujana Medithi Dr Jan 2021

Nutritional Aspects Related To Covid-19: A Bibliometric Analysis Using Scopus Database, Arti Muley Dr, Srujana Medithi Dr

Library Philosophy and Practice (e-journal)

Nutrition therapy has lately gained attention as an effective way of combating the novel Coronavirus 2019 (COVID-19), especially to address the immunity in an individual and their overall health. The present study is a bibliometric assessment of research conducted to understand the role of nutrition in treating COVID-19 which was carried out since the pandemic's sudden outburst during 2020 and 2021 and published in the Scopus database. A total of 93 publications were found, and the results were studied by evaluating these documents. The present analysis identifies the active countries where the research was conducted, various types of documents wherein …


Evaluation Of The Chest Computed Tomography And Hemogram Data In Patients Withcovid-19: The Importance Of Thymus, Vefa Çakmak, Atakan Yilmaz, Tuğba Sari, Pinar Çakmak, Mert Özen, Duygu Herek, Alten Oskay Jan 2021

Evaluation Of The Chest Computed Tomography And Hemogram Data In Patients Withcovid-19: The Importance Of Thymus, Vefa Çakmak, Atakan Yilmaz, Tuğba Sari, Pinar Çakmak, Mert Özen, Duygu Herek, Alten Oskay

Turkish Journal of Medical Sciences

Background/aim: To investigate the relationship between imaging findings and peripheral blood cell counts of COVID-19 patients and the degree of thymus fat involution of these patients. Materials and methods: Computed tomography (CT) images of 87 patients with COVID-19 positive through RT-PCR testing were evaluated retrospectively by two radiologists. Ground glass densities and other signs of viral pneumonia were recorded, lung involvement was scored quantitatively. The patients thymus fat involution was graded on CT. Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratios (PLR), lymphocyte and platelet counts were calculated. Imaging findings and degrees of thymus fat involution were compared with laboratory data. Results: Quantitative …


The Clinical Course Of Covid-19 In Hematopoietic Stem Cell Transplantation (Hsct)Recipients, Ayşe Karataş, Ümi̇t Yavuz Malkan, Mustafa Velet, Haluk Demi̇roğlu, Yahya Büyükaşik, Gülçi̇n Telli̇ Di̇zman, Ahmet Çağkan İnkaya, Batuhan Erdoğdu, Olgu Erki̇n Çinar, Eli̇fcan Aladağ Karakulak, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Osman İlhami̇ Özcebe, Ni̇lgün Sayinalp, Hakan Göker Jan 2021

The Clinical Course Of Covid-19 In Hematopoietic Stem Cell Transplantation (Hsct)Recipients, Ayşe Karataş, Ümi̇t Yavuz Malkan, Mustafa Velet, Haluk Demi̇roğlu, Yahya Büyükaşik, Gülçi̇n Telli̇ Di̇zman, Ahmet Çağkan İnkaya, Batuhan Erdoğdu, Olgu Erki̇n Çinar, Eli̇fcan Aladağ Karakulak, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Osman İlhami̇ Özcebe, Ni̇lgün Sayinalp, Hakan Göker

Turkish Journal of Medical Sciences

Background/aim: The disease caused by SARS-CoV-2 was named as COVID-19. There is as yet insufficient information about the effects of HSCT on the clinical course of COVID-19. In the present study, we aimed to investigate the clinical course of COVID-19 in patients who had undergone HSCT. Materials and methods: We analyzed baseline characteristics, clinical course and findings of COVID-19, hospitalization and death rates, overall survival, and case fatality rates of HSCT recipients diagnosed with COVID-19 retrospectively. Results: 57.6% of the patients underwent AHSCT, and 42.4% underwent allo-HSCT. 60.6%, 27.3%, and 12.1% of the patients had mild, moderate, and severe COVID-19 …


Interleukin-21: A Potential Biomarker For Diagnosis And Predicting Prognosis In Covid-19 Patients, Ni̇lüfer Ayli̇n Acet Öztürk, Ahmet Ursavaş, Asli Görek Di̇lektaşli, Ezgi̇ Demi̇rdöğen, Necmi̇ye Funda Coşkun, Dane Edi̇ger, Ayşe Esra Uzaslan, Di̇ğdem Yöyen Ermi̇ş, Mert Karaca, Orkun Eray Terzi̇, Merve Bayram, Di̇lara Ömer Topçu, Büşra Yi̇ği̇tli̇ler, Ahmet Yurttaş, Shahri̇yar Maharramov Jan 2021

Interleukin-21: A Potential Biomarker For Diagnosis And Predicting Prognosis In Covid-19 Patients, Ni̇lüfer Ayli̇n Acet Öztürk, Ahmet Ursavaş, Asli Görek Di̇lektaşli, Ezgi̇ Demi̇rdöğen, Necmi̇ye Funda Coşkun, Dane Edi̇ger, Ayşe Esra Uzaslan, Di̇ğdem Yöyen Ermi̇ş, Mert Karaca, Orkun Eray Terzi̇, Merve Bayram, Di̇lara Ömer Topçu, Büşra Yi̇ği̇tli̇ler, Ahmet Yurttaş, Shahri̇yar Maharramov

Turkish Journal of Medical Sciences

Background/aim: COVID-19 patients have a wide spectrum of disease severity. Several biomarkers were evaluated as predictors for progression towards severe disease. IL-21 is a member of common γ-chain cytokine family and creates some specific effects during programming and maintenance of antiviral immunity. We aimed to assess IL-21 as a biomarker for diagnosis and outcome prediction in patients hospitalized with COVID-19. Materials and methods: Patients with a preliminary diagnosis of COVID-19 and pneumonia other than COVID-19 admitted to a tertiary care hospital were included consecutively in this comparative study. Results: The study population consisted of 51 patients with COVID-19 and 11 …


Assessment Of Olfactory And Gustatory Functions In Covid-19 Patients, Muammer Meli̇h Şahi̇n, Eray Uzunoğlu, Mücahi̇t Yalçin, Gökçen Cesur, Mehmet Yildiz, Pinar Aysert Yildiz, Hasan Selçuk Özger, Süleyman Cebeci̇, Recep Karamert, Mehmet Düzlü, Hakan Tutar, Murat Di̇zbay, Alper Ceylan Jan 2021

Assessment Of Olfactory And Gustatory Functions In Covid-19 Patients, Muammer Meli̇h Şahi̇n, Eray Uzunoğlu, Mücahi̇t Yalçin, Gökçen Cesur, Mehmet Yildiz, Pinar Aysert Yildiz, Hasan Selçuk Özger, Süleyman Cebeci̇, Recep Karamert, Mehmet Düzlü, Hakan Tutar, Murat Di̇zbay, Alper Ceylan

Turkish Journal of Medical Sciences

Background/aim: This study aims to evaluate of olfactory and gustatory functions of COVID-19 patients and possible risk factors for olfactory and gustatory dysfunctions. Materials and methods: The cross-sectional study included adult patients who were diagnosed with COVID-19 in Gazi University Hospital between April 2020 and June 2020. Volunteered patients participated in a survey in which olfactory and gustatory functions and various clinical information were questioned. Sinonasal Outcome Test-22 was also administrated to all patients. Results: A hundred and seventy-one patients participated in this study. Olfactory and gustatory dysfunctions rates were 10.5% (n: 18) and 10.5% (n: 18), respectively. Patients without …


Effects Of Hydroxychloroquine And Favipiravir On Clinical Course In Outpatients Withcovid-19, Seyda Kayhan Ömeroğlu, Fehmi̇naz Temel, Di̇lek Altun, Mehmet Burak Öztop Jan 2021

Effects Of Hydroxychloroquine And Favipiravir On Clinical Course In Outpatients Withcovid-19, Seyda Kayhan Ömeroğlu, Fehmi̇naz Temel, Di̇lek Altun, Mehmet Burak Öztop

Turkish Journal of Medical Sciences

Background/aim: Due to the importance of early outpatient treatment to prevent hospitalization and disease progression, we examined the effects of hydroxychloroquine and favipiravir, which were initiated in early period, on the clinical course of COVID-19 outpatients. Materials and methods: Data of confirmed COVID-19 outpatients over a 4-month period were analyzed retrospectively. Public Health Management System (HSYS) was used for the case-based follow-up. Patients on antiviral therapy for at least five days, including hydroxychloroquine and / or favipiravir and patients who were followed-up for 30 days were included in this analysis. Results: We enrolled 1489 patients in this study. Overall, 775 …


Associations Between Genetic Variants In The Vitamin D Metabolism Pathway And Severity Of Covid-19 Among Uae Residents, Fatme Al-Anouti, Mira Mousa, Spyridon N. Karras, William B. Grant, Zainab Alhalwachi, Laila Abdel-Wareth, Maimunah Uddin, Nawal Alkaabi, Guan K. Tay, Bassam Mahboub, Habiba Alsafar Jan 2021

Associations Between Genetic Variants In The Vitamin D Metabolism Pathway And Severity Of Covid-19 Among Uae Residents, Fatme Al-Anouti, Mira Mousa, Spyridon N. Karras, William B. Grant, Zainab Alhalwachi, Laila Abdel-Wareth, Maimunah Uddin, Nawal Alkaabi, Guan K. Tay, Bassam Mahboub, Habiba Alsafar

Research outputs 2014 to 2021

Vitamin D has many effects on cells in the immune system. Many studies have linked low vitamin D status with severity of COVID-19. Genetic variants involved in vitamin D metabolism have been implicated as potential risk factors for severe COVID-19 outcomes. This study investigated how genetic variations in humans affected the clinical presentation of COVID-19. In total, 646 patients with SARS-CoV-2 infection were divided into two groups: noncritical COVID-19 (n = 453; 70.12%) and a critical group (n = 193; 29.87%). Genotype data on the GC, NADSYN1, VDR, and CYP2R1 genes along with data on serum 25-hydroxyvitamin D levels were …


Life In A Time Of Covid: A Mixed Method Study Of The Changes In Lifestyle, Mental And Psychosocial Health During And After Lockdown In Western Australians, Ranila Bhoyroo, Paola Chivers, Lynne Millar, Caroline Bulsara, Ben Piggott, Michelle Lambert, Jim Codde Jan 2021

Life In A Time Of Covid: A Mixed Method Study Of The Changes In Lifestyle, Mental And Psychosocial Health During And After Lockdown In Western Australians, Ranila Bhoyroo, Paola Chivers, Lynne Millar, Caroline Bulsara, Ben Piggott, Michelle Lambert, Jim Codde

Research outputs 2014 to 2021

Background: Since the beginning of the COVID-19 pandemic, the Western Australian government imposed multiple restrictions that impacted daily life activities and the social life. The aim of this study was to examine the effects of COVID-19 lockdown on the community’s physical, mental and psychosocial health. Methods: Approximately 2 months after a three-month lockdown, a cross-sectional study was opened to Western Australian adults for an 8-week period (25th August – 21 October 2020). Participants competed a 25-min questionnaire adapted from the Western Australia Health and Wellbeing Surveillance system. Participants provided information on their socio-demographic status, lifestyle behaviours, mental health, and psychosocial …


Editorial: Covid-19, Corporate Governance, Sustainability, And The Post-Neoliberal World, Marie Dela Rama, Julie Crews Jan 2021

Editorial: Covid-19, Corporate Governance, Sustainability, And The Post-Neoliberal World, Marie Dela Rama, Julie Crews

Research outputs 2014 to 2021

Welcome to this special issue of Corporate Governance and Sustainability Review focusing on the impact of thecoronavirus (COVID-19) on societies and economies worldwide. The five papers in this special issue reflect the initial impact of the COVID-19 pandemic,in its first year,on corporate governance and sustainability. What is common throughout these papers is how the pandemic has created disequilibria for many organisations. The question continues to be posed as to the new forms of organising and managing as the world reorientates or pivots in a pandemic and post-pandemic world.


Vaccines Are Not Yet A Silver Bullet: The Imperative Of Continued Communication About The Importance Of Covid-19 Safety Measures, Zhaohui Su, Jun Wen, Dean Mcdonnell, Edmund Goh, Xiaoshan Li, Sabina Šegalo, Junaid Ahmad, Ali Cheshmehzangi, Yu-Tao Xiang Jan 2021

Vaccines Are Not Yet A Silver Bullet: The Imperative Of Continued Communication About The Importance Of Covid-19 Safety Measures, Zhaohui Su, Jun Wen, Dean Mcdonnell, Edmund Goh, Xiaoshan Li, Sabina Šegalo, Junaid Ahmad, Ali Cheshmehzangi, Yu-Tao Xiang

Research outputs 2014 to 2021

COVID-19 vaccines are by no means a silver bullet. With more COVID-19 vaccines expecting approval in the coming months, it is necessary to note that vaccine availability does not equate to vaccine accessibility, nor vaccine efficacy. Some research suggests that approximately 9 out of 10 individuals living in lower-income countries will not have access to COVID-19 vaccines until 2023 or later. For higher-income countries, such as the United States, the prevalence of vaccine hesitancy may further compound the situation. These insights combined, in turn, emphasize the fact that even though COVID-19 vaccines are becoming more available, safety measures (e.g., face …


All Around Suboptimal Health — A Joint Position Paper Of The Suboptimal Health Study Consortium And European Association For Predictive, Preventive And Personalised Medicine, Wei Wang, Yuxiang Yan, Zheng Guo, Haifeng Hou, Monique Garcia, Xuerui Tan, Enoch O. Anto, Gehendra Mahara, Yulu Zheng, Bo Li, Timothy Kang, Zhaohua Zhong, Youxin Wang, Xiuhua Guo, Olga Golubnitschaja, Suboptimal Health Study Consortium And European Association For Predictive, Preventive And Personalised Medicine Jan 2021

All Around Suboptimal Health — A Joint Position Paper Of The Suboptimal Health Study Consortium And European Association For Predictive, Preventive And Personalised Medicine, Wei Wang, Yuxiang Yan, Zheng Guo, Haifeng Hou, Monique Garcia, Xuerui Tan, Enoch O. Anto, Gehendra Mahara, Yulu Zheng, Bo Li, Timothy Kang, Zhaohua Zhong, Youxin Wang, Xiuhua Guo, Olga Golubnitschaja, Suboptimal Health Study Consortium And European Association For Predictive, Preventive And Personalised Medicine

Research outputs 2014 to 2021

First two decades of the twenty-first century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of patients diagnosed with cardiovascular diseases and the type 2 diabetes mellitus, breast, lung, liver and prostate malignancies, neurological, sleep, mood and eye disorders, amongst others. Consequent socio-economic burden is tremendous. Unprecedented decrease in age of maladaptive individuals has been reported. The absolute majority of expanding non-communicable disorders carry a chronic character, over a couple of years progressing from reversible suboptimal health conditions to irreversible severe pathologies and cascading collateral complications. The time-frame between onset of SHS and clinical manifestation …


Profile Of Immunoglobulin G N-Glycome In Covid-19 Patients: A Case-Control Study, Haifeng Hou, Huan Yang, Pengcheng Liu, Changwu Huang, Meng Wang, Yuejin Li, Mingsong Zhu, Jing Wang, Yuan Xu, Youxin Wang, Qingwei Ma, Dong Li, Pu Liao, Wei Wang Jan 2021

Profile Of Immunoglobulin G N-Glycome In Covid-19 Patients: A Case-Control Study, Haifeng Hou, Huan Yang, Pengcheng Liu, Changwu Huang, Meng Wang, Yuejin Li, Mingsong Zhu, Jing Wang, Yuan Xu, Youxin Wang, Qingwei Ma, Dong Li, Pu Liao, Wei Wang

Research outputs 2014 to 2021

Coronavirus disease 2019 (COVID-19) remains a major health challenge globally. Previous studies have suggested that changes in the glycosylation of IgG are closely associated with the severity of COVID-19. This study aimed to compare the profiles of IgG N-glycome between COVID-19 patients and healthy controls. A case-control study was conducted, in which 104 COVID-19 patients and 104 age- and sex-matched healthy individuals were recruited. Serum IgG N-glycome composition was analyzed by hydrophilic interaction liquid chromatography with the ultra-high-performance liquid chromatography (HILIC-UPLC) approach. COVID-19 patients have a decreased level of IgG fucosylation, which upregulates antibody-dependent cell cytotoxicity (ADCC) in …


Covid-19 Disease Severity And Death In Relation To Vitamin D Status Among Sars-Cov-2-Positive Uae Residents, Habiba Alsafar, William B. Grant, Rafiq Hijazi, Maimunah Uddin, Nawal Alkaabi, Guan Tay, Bassam Mahboub, Fatme Al Anouti Jan 2021

Covid-19 Disease Severity And Death In Relation To Vitamin D Status Among Sars-Cov-2-Positive Uae Residents, Habiba Alsafar, William B. Grant, Rafiq Hijazi, Maimunah Uddin, Nawal Alkaabi, Guan Tay, Bassam Mahboub, Fatme Al Anouti

Research outputs 2014 to 2021

Insufficient blood levels of the neurohormone vitamin D are associated with increased risk of COVID-19 severity and mortality. Despite the global rollout of vaccinations and promising preliminary results, the focus remains on additional preventive measures to manage COVID-19. Results conflict on vitamin D’s plausible role in preventing and treating COVID-19. We examined the relation between vitamin D status and COVID-19 severity and mortality among the multiethnic population of the United Arab Emirates. Our observational study used data for 522 participants who tested positive for SARS-CoV-2 at one of the main hospitals in Abu Dhabi and Dubai. Only 464 of those …


The Missing Link Between Medical Science Knowledge And Public Awareness: Implications For Tourism And Hospitality Recovery After Covid-19, Jun Wen, Haifeng Hou, Metin Kozak, Fang Meng, Chung-En Yu, Wei Wang Jan 2021

The Missing Link Between Medical Science Knowledge And Public Awareness: Implications For Tourism And Hospitality Recovery After Covid-19, Jun Wen, Haifeng Hou, Metin Kozak, Fang Meng, Chung-En Yu, Wei Wang

Research outputs 2014 to 2021

Purpose: As the world grapples with the pervasive effects of the coronavirus pandemic, a notable disconnect has emerged in the public's understanding of scientific and medical research. Particularly, the travel industry has become unquestionably vulnerable amid the COVID-19 outbreak; this pandemic has interrupted the industry's operations with devastating economic consequences. This paper aims to highlight the importance of deconstructing barriers between medical science and public awareness related to COVID-19, taking tourism as a case in point. It also discusses the role of interdisciplinary research in facilitating the tourism and hospitality industry's recovery and alleviating tourists' uncertainties in the wake of …


Strategic Implications Of Covid-19: Considerations For Georgia’S Rural Health Providers, Bettye A. Apenteng, Linda Kimsey, Charles Owens, Samuel T. Opoku, Angela Peden, William Mase Jan 2021

Strategic Implications Of Covid-19: Considerations For Georgia’S Rural Health Providers, Bettye A. Apenteng, Linda Kimsey, Charles Owens, Samuel T. Opoku, Angela Peden, William Mase

Health Policy & Community Health: Faculty Publications

Whether rural hospitals and providers have seen a surge in COVID-19 cases or a reduction in patients seeking care since the pandemic began, their financial condition has been negatively impacted. Many providers have now received some emergency funding through the Coronavirus Aid, Relief, and Economic Security Act and the Payroll Protection Program but these are likely only short-term fixes. For many, the crisis has exacerbated already existing problems. Notable among these problems are volume declines, supply chain disruptions, and workforce concerns. While these problems require immediate action, two longer-term systemic changes to rural healthcare delivery are needed to address them. …


Understanding And Promoting Racial Diversity In Healthcare Settings To Address Disparities In Pandemic Crisis Management, Azza Sarfraz, Zouina Sarfraz, Alanna Barrios, Kuchalambal Agadi, Sindhu Thevuthasan, Krunal Pandav, Manish Kc, Muzna Sarfraz, Pedram Rad, George Michel Jan 2021

Understanding And Promoting Racial Diversity In Healthcare Settings To Address Disparities In Pandemic Crisis Management, Azza Sarfraz, Zouina Sarfraz, Alanna Barrios, Kuchalambal Agadi, Sindhu Thevuthasan, Krunal Pandav, Manish Kc, Muzna Sarfraz, Pedram Rad, George Michel

Department of Paediatrics and Child Health

Background: Health disparities have become apparent since the beginning of the COVID-19 pandemic. When observing racial discrimination in healthcare, self-reported incidences, and perceptions among minority groups in the United States suggest that, the most socioeconomically underrepresented groups will suffer disproportionately in COVID-19 due to synergistic mechanisms. This study reports racially-stratified data regarding the experiences and impacts of different groups availing the healthcare system to identify disparities in outcomes of minority and majority groups in the United States.
Methods: Studies were identified utilizing PubMed, Embase, CINAHL Plus, and PsycINFO search engines without date and language restrictions. The following keywords were used: …


Secretion Of Von Willebrand Factor And Suppression Of Adamts-13 Activity By Markedly High Concentration Of Ferritin, Dalia A Bashir, Qi Da, Subhashree Pradhan, Nitin Sekhar, Christian Valladolid, Fong Lam, Danielle Guffey, Jordana Goldman, Moreshwar S Desai, Miguel A Cruz, Carl Allen, Trung C Nguyen, K Vinod Vijayan Jan 2021

Secretion Of Von Willebrand Factor And Suppression Of Adamts-13 Activity By Markedly High Concentration Of Ferritin, Dalia A Bashir, Qi Da, Subhashree Pradhan, Nitin Sekhar, Christian Valladolid, Fong Lam, Danielle Guffey, Jordana Goldman, Moreshwar S Desai, Miguel A Cruz, Carl Allen, Trung C Nguyen, K Vinod Vijayan

Faculty, Staff and Students Publications

Hyperferritinemia is associated with poor outcomes in critically ill patients with sepsis, hemophagocytic lymphohistiocytosis (HLH), macrophage activation syndromes (MAS) and coronavirus disease 19 (COVID-19). Autopsies of hyperferritinemic patients that succumbed to either sepsis, HLH, MAS or COVID-19 have revealed disseminated microvascular thromboses with von Willebrand factor (VWF)-, platelets-, and/or fibrin-rich microthrombi. It is unknown whether high plasma ferritin concentration actively promotes microvascular thrombosis, or merely serves as a prognostic biomarker in these patients. Here, we show that secretion of VWF from human umbilical vein endothelial cells (HUVEC) is significantly enhanced by 100,000 ng/ml of recombinant ferritin heavy chain protein (FHC). …


Characteristics And Outcomes Of In-Hospital Cardiac Arrest In Covid-19 A Systematic Review And Meta-Analysis, Lukasz Szarpak, Magdalena Borkowska, Frank W Peacock, Zubaid Rafique, Aleksandra Gasecka, Jacek Smereka, Katarzyna Pytkowska, Marta Jachowicz, Lukasz Iskrzycki, Natasza Gilis-Malinowska, Milosz J Jaguszewski Jan 2021

Characteristics And Outcomes Of In-Hospital Cardiac Arrest In Covid-19 A Systematic Review And Meta-Analysis, Lukasz Szarpak, Magdalena Borkowska, Frank W Peacock, Zubaid Rafique, Aleksandra Gasecka, Jacek Smereka, Katarzyna Pytkowska, Marta Jachowicz, Lukasz Iskrzycki, Natasza Gilis-Malinowska, Milosz J Jaguszewski

Faculty, Staff and Students Publications

BACKGROUND: The purpose herein, was to perform a systematic review of interventional outcome studies in patients with in-hospital cardiac arrest before and during the coronavirus disease 2019 (COVID-19) pandemic period.

METHODS: A meta-analysis was performed of publications meeting the following PICOS criteria: (1) participants, patients > 18 years of age with cardiac arrest due to any causes; (2) intervention, cardiac arrest in COVID-19 period; (3) comparison, cardiac arrest in pre-COVID-19 period; (4) outcomes, detailed information for survival; (5) study design, randomized controlled trials, quasi-randomized or observational studies comparing cardiac arrest in COVID-19 and pre-COVID-19 period for their effects in patients with …


Thyroid Storm In A Patient With Covid-19, Angela N Rao, Ruaa Y Al-Ward, Ruchi Gaba Jan 2021

Thyroid Storm In A Patient With Covid-19, Angela N Rao, Ruaa Y Al-Ward, Ruchi Gaba

Faculty, Staff and Students Publications

OBJECTIVE: A thyroid storm is a severe exacerbation of thyrotoxicosis that can cause significant morbidity and mortality. The emergence of the novel coronavirus (SARS-CoV-2) that originated in Wuhan, China, has become a worldwide pandemic. We present the first documented case of thyroid storm (as defined by the Burch-Wartofsky criteria) in a patient with COVID-19.

METHODS: Laboratory and diagnostic studies, including thyroid function tests, thyroid antibody testing, SARS-CoV-2 nasopharyngeal polymerase chain reaction testing, and thyroid ultrasound were performed.

RESULTS: A 25-year-old woman presented to the hospital with dry cough, dyspnea, palpitations, weight loss, diarrhea, and anxiety. Physical examination revealed exophthalmos with …


Evaluating Employees’ Experiences In Implementing Covid-19 Safety Protocols In Ontario Parks, Jessica Kaatz Jan 2021

Evaluating Employees’ Experiences In Implementing Covid-19 Safety Protocols In Ontario Parks, Jessica Kaatz

Theses and Dissertations (Comprehensive)

The COVID-19 pandemic has created a wide range of public health challenges for park management and staff in Ontario. Green spaces have become a source of resilience during the spread of the virus, partly due to their proven positive impacts on social, mental and physical well-being. With the introduction of social distancing protocols, utilization of Personal Protective Equipment (PPE), and standardizing constant sanitation efforts, park employees are more responsible than ever for the daily implementation of rules governing park safety and security. At the same time, increased visitor numbers and continually changing government protocols that varied between regional jurisdictions have …


Still Learning: Covid Through The Eyes Of A Medical Student, Alexis Strahan Dec 2020

Still Learning: Covid Through The Eyes Of A Medical Student, Alexis Strahan

HCA Healthcare Journal of Medicine

As a first-year medical student when the COVID-19 pandemic found a foothold, I felt an overwhelming amount of emotions that accompanied the pandemic’s spread. Fear, although a reasonable choice, was not the first emotion that I experienced. In fact, it was a general feeling of paralysis. I had not six months prior taken an oath to commit my career and life to the service of the public’s health care needs, yet I could provide little more than the textbook knowledge of biochemistry or genetics from my first semester of learning. My hands felt unarmed and unskilled for the fight. What …


Covid-19: Race For Vaccine, L. Hayley Burgess, Jason J. Braithwaite, Emily Singleton, Aaron M. Young, Mandelin K. Cooper Dec 2020

Covid-19: Race For Vaccine, L. Hayley Burgess, Jason J. Braithwaite, Emily Singleton, Aaron M. Young, Mandelin K. Cooper

HCA Healthcare Journal of Medicine

The world is in the midst of a pandemic from COVID-19, a disease caused by the virus SARS-CoV-2. Despite broad mitigation efforts, new cases continue with 74 million cases and 1.6 million deaths worldwide. Regardless of previous research efforts, there is no commercially available vaccine for any coronavirus. Novel vaccine development has historically taken at least 10 years from discovery to availability with only a 6% market entry probability.

With the global impact, there is an urgency to expedite a vaccine to protect the population. The U.S. government launched Operation Warp Speed with the goal to produce and deliver 300 …


Importance Of Awareness Of Adverse Drug Reaction Reporting During The Covid-19 Pandemic, Heather Ellis, Hale Z. Toklu Dec 2020

Importance Of Awareness Of Adverse Drug Reaction Reporting During The Covid-19 Pandemic, Heather Ellis, Hale Z. Toklu

HCA Healthcare Journal of Medicine

Health care professionals hold the responsibility of reporting any adverse drug reactions in order to learn about new therapy and how best to safely care for our patients. The information derived from case publications and FDA MedWatch reports are essential to accumulate information and increase awareness for the possible risks of new drugs.


Gender In The Time Of Covid-19: Evaluating National Leadership And Covid-19 Fatalities, Leah C. Windsor, Gina Yannitell Reinhardt, Alistair J. Windsor, Robert Ostergard, Susan Allen, Courtney Burns, Jarod Giger, Reed Wood Dec 2020

Gender In The Time Of Covid-19: Evaluating National Leadership And Covid-19 Fatalities, Leah C. Windsor, Gina Yannitell Reinhardt, Alistair J. Windsor, Robert Ostergard, Susan Allen, Courtney Burns, Jarod Giger, Reed Wood

Social Work Faculty Publications

In this paper we explore whether countries led by women have fared better during the COVID-19 pandemic than those led by men. Media and public health officials have lauded the perceived gender-related influence on policies and strategies for reducing the deleterious effects of the pandemic. We examine this proposition by analyzing COVID-19-related deaths globally across countries led by men and women. While we find some limited support for lower reported fatality rates in countries led by women, they are not statistically significant. Country cultural values offer more substantive explanation for COVID-19 outcomes. We offer several potential explanations for the pervasive …


Let Nutrition Be Your Vaccine Amid Covid-19- A Narrative Review, Vidya Rajesh Dec 2020

Let Nutrition Be Your Vaccine Amid Covid-19- A Narrative Review, Vidya Rajesh

Manipal Journal of Medical Sciences

There has been a growing body of evidence highlighting the radical effect of nutrition on the immune system and disease susceptibility. The current COVID-19 crisis awakens an urgent calling for optimum nutrition which boosts immunity and prevents diseases, just like a vaccine. Though there have been several national guidelines regarding diet during COVID-19, there has been sparse research and literature available in this field. This review aims to summarise the existing evidence on various aspects of nutrition and immunity pertaining to the COVID-19 crisis. Literature and search strategy included PubMed and Google Scholar for articles on various aspects of nutrition …


“Sampark Snehi”: Telemedicine Consultation In Covid-19 Times At A Private Medical College Hospital – Digitalised Solution, Vijetha Belle Dec 2020

“Sampark Snehi”: Telemedicine Consultation In Covid-19 Times At A Private Medical College Hospital – Digitalised Solution, Vijetha Belle

Manipal Journal of Medical Sciences

Every life is precious and every patient matters: In a country with 5.5 government beds for 10,000 population, even a marginal increase in hospitalization increases the pressure on the system exponentially. The spread of COVID-19 has kindled the need for transformation from traditional face-to-face doctorpatient communication to a telehealth platform. During the lockdown, reduced access to both outpatient and hospitalization services is proving to be fatal for countless non-covid patients. Taking lead in addressing the health care needs and demands of the society we cater to, E-consultation which has been initiated by most of the medical colleges providing tertiary care, …


The Legacy Of Racism And Covid-19, Adedayo Okanlawon Dec 2020

The Legacy Of Racism And Covid-19, Adedayo Okanlawon

MEDI 9331 Scholarly Activities Clinical Years

This perspective piece discusses the interplay between Covid-19, the legacy of racism in America, and their synergistic effects on the black community. Personal racially charged experiences in conjunction with notable stories of injustice in medicine are used to set the stage. The pandemic's disparate impact on black communities are then discussed with suggestion on how to mitigate these issues.


Community Engagement In Covid-19 Responses: Evidence From Qualitative Interface With Community Opinion Leaders In Enugu, Nigeria, Prince Agwu, Chinweoke Methodius Ugwu, Chidera Florence Eke Dec 2020

Community Engagement In Covid-19 Responses: Evidence From Qualitative Interface With Community Opinion Leaders In Enugu, Nigeria, Prince Agwu, Chinweoke Methodius Ugwu, Chidera Florence Eke

ASEAN Journal of Community Engagement

Successful stories of community engagement existed during the Ebola disease outbreak in Liberia, indicating that a combination of government and community efforts are needed in addressing pandemics or epidemics. However, for communities to rise to the challenge of containing and combatting the spread of any disease, they must be communicated most effectively and supported by the government. Therefore, our study investigates how applicable successful community engagement has been in the charge against the Coronavirus disease 2019 (COVID-19) in Nigeria. Through telephone interviews, we sourced data from 12 community opinion leaders in Enugu State, Nigeria. After conducting a thematic analysis of …