Medicine and Health Sciences Commons^™

Observation And Reflection Of Neighborhood And Community 2026: The Employment Of Residents In 48203 & Its Impact, Mahmood Sanad, Michelle Wang, Steven Katzman, Nikhil Uppal, Alvin Dong, Yuting Ruan, Makayla Hickmon, Dhara Patel

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: A Reflection On The Limited Resources Available For A Healthy Lifestyle, Jana Hatahet, Steven Jones, Laila Shatela, Pegi Laci, Anushka Dalvi, Michael Becker, Albert Oh, Anthony Marquez

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Provider Availability, Healthcare Coverage, Access To Healthy Food Options, Income, Neighborhood Walkability, And School/Education Reflection, Kayla Hogan, Elizabeth Ajaero, Muhammad Hashem, Alina Ciesielski, Amanda Elashoff, Erik Pedersen, Hamza Mohammad, Tyler Dawson

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Social Determinants In Action: A Field Reflection On Community Health, Jamaica Jordan, Razanne Zaghloul, Raj Khuperkar, Lissette Valdez, Nathan Morren, Cole Duvall, Alexis King

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Education, Environmental Conditions, And Food Insecurities Reflection, Skylar Hall, Badruddin Mahamed, Jenna Andersen, Evan Robyns, Andrew Singh, Julia Correll, Yousef El-Magharbel, Tiffany Adam

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Observation And Reflection Of Transportation Needs, Aaron Crump, Mohamed El-Souri, Rawan Antar, Sriram Garapati, Olivia Fras, Jai Patel, Lucy Zhang, Laya Dasari

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Neighborhood And Built Environment: Facilitating Safety, Community, And Preventative Health, Zachary Hart, Batoul Dabajeh, Maaz Munawar, Josie Mclearen, Theodore Belecciu, Laura Zvinys, Tarek Harhash, Emily Critchfield

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Food Insecurity, Transportation, Healthcare Access, And Reflection, Mariann Hayek, Noah Weslock, Arya Mashraghy, Mahathi Krothapalli, Abhishek Thakur, Fatima Alemam, Kyle Kramer

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Neighborhood, Environment, And Reflection, Olma Tadesse, Kush Amin, Devon Roe, Anjie Dinakin, Matt Minasian, Arisha Arain, Dave Sreedhar, Ashley Yuran

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Food Desert, Walking Infrastructure, And Primary Care Access Observed In 48203, Christina Barchini, Jad Fawaz, Brayden Moore, Emma Pastoor, Samuel Rest, Hamed Selemani

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: 48219 Beyond The Zip Code, Justin Darragh, Adhithi Keerthana Athikumar, Muaaz Akhtar, Dania Zeidan, Nathaniel Edwards, Trina Alimi, Jonah Brand, Beatrice White

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Understanding Social Determinants In 48203, Jared Lin, Ryan The, Russell Elkus, Aayushi Jani, Michaela Yamine, Riona O'Donnell, Mariam Duhaini

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Access To Education And Nutritious Foods, Maurgan Lee, Kailey Carner, Tarek Atasi, Michael Mclellan, Alec Brook, Ashley Schehr, Namitha Bhat, Syed Kaushik

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Observation And Reflection Of Education, Transportation, And Food Insecurity At Detroit, Sindi Roko, Kaylee Chan, Sarah Noonan, Alfonso Vaziriyan-Sani, Jelani Shadd, Ritika Tiwary, Samir Khan

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Barriers To Health In Detroit’S New Center: Addressing Food, Housing, And Accessibility, Yasmeen Jazaerly, Ivan Kyagaba, Jahnavi Rajagopal, Frances-Denise Fajardo, Ahmed Makled, Ahmed Hassanin, Jayson Bakshi, Victoria Potter

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Observation And Reflection Of Highland Park, Mohamed Ramadan, Marni Murez, Saatvik Vaishnav, Sathyagopal Siddapureddy, Janiya Brooks

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Observation And Reflection Of Disparities In Access To Healthy Foods, Education, And Stable Healthcare, Kerolos Aziz, Uma Sriram, Sarah Yee, Hassan Saad, Jessica Delgado, Shiyuan Gong, Seyrona Mclean

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Reflection On Neighborhood Environment And Economic Instability As Barriers To Health, Charity Godbold, Sarah Syeda, Zachary Houslander, Sydney Kelly, Jason Fahmy, Eliezer Ponce De Leon, Jessica Wang, Omar Tayeb

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Systemic Barriers In 48203—Poverty, Food Deserts, And Inadequate Infrastructure—Directly Impact The Health And Futures Of Its Residents., Kerestin Aziz, Sanjana Aiella, Brady Bak, Maanas Sharma, Catherine Hofley, Silas Stewart, Ahmed Marabeh, Samantha Hoey

Patient Education Projects

No abstract provided.

Observation And Reflection Of Neighborhood And Community 2026: Housing, Transportation, & Education And Reflection, Seareen Maaita, Alexis Kmak, Balraj Dhanoa, Sergio Guerra, Shrikar Modukuri, Gwenyth Sirrine, Ciara Hancock, Mohamed Ramadan

Patient Education Projects

No abstract provided.

Discharge Process Improvement Initiative Using An N-By-T Strategy In A Progressive Care Unit In An Acute Care Setting, Sukhvir Walia

Doctor of Nursing Practice Projects

Background

Timely and efficient patient discharge processes are crucial for enhancing hospital throughput, reducing emergency department boarding, optimizing inpatient bed utilization, and ensuring safe transitions of care. Delayed hospital discharges contribute to prolonged hospitalizations, operational inefficiencies, increased healthcare expenditures, and decreased patient satisfaction. Progressive care units (PCU) are particularly vulnerable to discharge delays because patients frequently require multidisciplinary coordination before safe discharge can occur.

Purpose

The purpose of this quality improvement project was to evaluate the effectiveness of implementing a structured discharge readiness checklist combined with an n-by-T discharge planning strategy during multidisciplinary patient progressive rounds (PPRs) to improve discharge …

Psychotropic Medications And Their Interactions With Subcortical Brain Volume In Bipolar Disorder: An Enigma Mega-Analysis, Sinead King, John O'Connor, Emma Corley, Giulia Tronchin, Elisa Fontana, Leila Nabulsi, Melody J Y Kang, Joaquim Radua, Brian Hallahan, Christoph Abé, Martin Alda, Dag Alnæs, Silvia Alonso-Lana, Silvia Amoretti, Jochen Bauer, Francesco Benedetti, Klaus Berger, Michael Berk, Erlend Bøen, Joscha Böhnlein, Birgitte Boye, Beatrice Bravi, Erick J Canales-Rodríguez, Udo Dannlowski, Caroline Demro, Annabella Di Giorgio, Ana M Diaz-Zuluaga, Torbjørn Elvsåshagen, Pauline Favre, Tracy Erwin-Grabner, María Florencia Forte, Janice M Fullerton, Lisa S Furlong, Susan L Rossell, David C Glahn, Benjamin I Goldstein, Ian H Gotlib, Roberto Goya-Maldonado, Melissa J Green, Dominik Grotegerd, Oliver Gruber, Bartholomeus C M Haarman, Tim Hahn, Tomas Hajek, Leonie Hater, Marco Hermesdorf, Josselin Houenou, Fleur M Howells, James A Karantonis, Kody G Kennedy, Tilo Kircher, Anna Luisa Klahn, Maximilian Konowski, Bernd Krämer, Elijah Lahud, Rayus Kuplicki, Mikael Landén, Carlos López-Jaramillo, Bradley J Macintosh, Hannah Meinert, Susanne Meinert, Elisa M T Melloni, Philip B Mitchell, Benson Mwangi, Igor Nenadić, Bronwyn J Overs, Nadine Parker, Godfrey Pearlson, Edith Pomarol-Clotet, James J Prisciandaro, Yann Quidé, Gloria Roberts, Amanda Rodrigue, Elena Rodríguez-Cano, Lisa Rauer, Matthew D Sacchet, Raymond Salvador, Fabio Sambataro, Theodore D Satterthwaite, Jonathan Savitz, Freda Scheffler, Navid Schürmeyer, Chen Shen, Kang Sim, Jair C Soares, Aleix Solanes, Márcio Gerhardt Soeiro-De-Souza, Scott R Sponheim, Dan J Stein, Frederike Stein, Henk S Temmingh, Lea Teutenberg, Sophia I Thomopoulos, Snezana Urosevic, Tamsyn E Van Rheenen, Eduard Vieta, Lars T Westlye, Daniel H Wolf, Mon-Ju Wu, Lakshmi N Yatham, Giovana B Zunta-Soares, Dara M Cannon, Paul M Thompson, Ole A Andreassen, Christopher R K Ching, Colm Mcdonald

Faculty, Staff and Student Publications

MRI studies in bipolar disorder (BD) have yielded inconsistent findings, partly due to the varied use of psychotropic medications. This study utilised a mega-analysis approach, accounting for concurrent medication status (syndrome-based and Neuroscience-based Nomenclature (NbN) classifications), in order to assess the association of medication status with subcortical brain volumes in BD. Data from 2,664 BD patients and 4,065 controls (CN) were pooled from 34 research groups as part of the ENIGMA Bipolar Disorder Working Group. Standardized ENIGMA protocols were used to measure subcortical brain volumes. Linear-mixed-effects regression evaluated the association between psychotropic medications and subcortical volumes, and moderation analyses explored …

Intravenous Buprenorphine Reversed Opioid-Induced Respiratory Depression Without Precipitating Withdrawal In Emergency Department Patients, Anthony Spadaro, Nicholas Imperato, Jaclyn Scalgione, Cynthia Santos

Faculty, Staff and Student Publications

Objective: Buprenorphine is a high-affinity partial agonist that can displace full opioid agonists and could be used to reverse opioid-induced respiratory depression. There is scant evidence to support the use of buprenorphine in an acute opioid overdose to reverse respiratory depression in the era of high fentanyl prevalence in the drug supply. This is a case series of four patients with signs and symptoms of an opioid overdose who showed clinical improvement after receiving intravenous buprenorphine.

Method: A case series of adult emergency department patients treated at a single urban academic medical center was reviewed by the authors, who determined …

The Impact Of Rapid Infusers On The Hemostatic Potential Of Cryoprecipitate Products, Connor D Purvis, Samantha Redden, Andrew Jacobson, Yao-Wei Wang, Julie Campbell, Jessica Cardenas, Jan-Michael Van Gent, Bryan A Cotton

Faculty, Staff and Student Publications

Background: In cases of massive transfusion, intravenous access can be limited. Additionally, delivering different products through separate lines and infusion methods adds unnecessary steps. RBC, plasma, and whole blood (WB) are delivered via rapid infusers; cryoprecipitate (CRYO) is infused through separate access and is not approved with these devices.

Study design and methods: We examined the impact of different transfusion methods on hemostatic performance and factor activity using two available CRYO products. Ten bags of CRYO, ten bags pathogen-reduced CRYO (Intercept® Fibrinogen Complex, IFC), and 20 units of WB were obtained. Each CRYO bag was infused with one unit of …

Estrogen As A Therapeutic Agent: Targeting Endotheliopathy And Coagulopathy In Trauma, Niruktha Raghavan, Mira Patel, Bryan A Cotton, Julia Coleman, Donald Jenkins

Faculty, Staff and Student Publications

Background: Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma-induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need for new precision resuscitation strategies that acknowledge factors like biological sex.

Design: The central hypothesis is that estrogen confers a survival advantage in hormonally active females through a dual action: endothelial cell stabilization (halting glycocalyx shedding) and its inherent procoagulant effect. The analysis assesses the therapeutic potential of both exogenous estrogen and female-derived blood products …

Declaring Futility After Traumatic Injury And The Burden Of Failure On The Surgeon, Jan-Michael Van Gent, Bryan A Cotton

Faculty, Staff and Student Publications

In this edition of the THOR supplement in Transfusion, there are two articles that deal with resuscitation futility and transfusion. In one article, Yazer et al. delve into the details of the studies outlined in this editorial and summarize the literature on the topic of transfusion and futility. The second article by Dr. Jay Malone discusses the ethical issues surrounding massive transfusion and resuscitation. Taken together, these articles address the clinical and ethical issues surrounding this very emotive and difficult topic.

Surgical Timing After Acromioclavicular Joint Separation: Association With Clinical Outcomes, Mallory B Lane, Jacob Siahaan, James M Gregory

Faculty, Staff and Student Publications

Background: Treatment of acromioclavicular joint (ACJ) separations continually lacks consensus between providers, and while low-grade injuries generally respond well to conservative management, high-grade injury management is more complex. For patients requiring surgery, the effect of the timing of surgery with respect to the original injury on clinical outcomes remains unclear.

Hypothesis: Clinical outcome measures would worsen as the time between ACJ dislocation injury and surgery increased.

Study design: Cohort study; Level of evidence, 3.

Methods: A large nationwide insurance claims database was queried for patients who had an ACJ dislocation injury using International Classification of Diseases, Ninth and Tenth Revision …

A Rare Case Of Gastric Ascariasis, Sharon Pan, Kevin Yu, Blaine A Mathison, Yan Gao, Marc Roger Couturier, Salem Muayad, Violeta Chávez, Ranya Selim

Faculty, Staff and Student Publications

Background: Ascariasis, caused by the parasitic roundworm Ascaris lumbricoides, is one of the most common helminthic infections globally. Spread by contaminated soil through the fecal-oral route, A. lumbricoides typically infects the small intestine and has rarely been reported to infect the stomach.

Case summary: We describe an unusual case of a male in his 30s with a history of neuroendocrine tumor (NET) who immigrated from Colombia and who underwent esophagogastroduodenoscopy (EGD) and colonoscopy for further evaluation of abdominal pain. He was incidentally found to have a female Ascaris worm in his stomach that was retrieved during the EGD.

Conclusion: …

An Assessment Of Green Plasma: The In Vitro Hemostatic Superiority Of A Currently Discarded Blood Product, Samantha C Redden, David J Sun, Yao-Wei W Wang, Elizabeth Hartwell, Jessica C Cardenas, Scott D Olson, Bryan A Cotton

Faculty, Staff and Student Publications

Introduction: Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green-colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.

Study design & methods: We obtained 90 units of plasma from our regional blood center: 30 units of visible green plasma and 60 units of standard-color plasma divided between male and female donors. We collected clinical data such as age, sex, ethnicity, and number of pregnancies. We then assessed the hemostatic …

Brief Report: Hepatitis B Vaccination Histories In Persons With Hiv Needing Revaccination, Minhee Kang, Triin Umbleja, Anchalee Avihingsanon, Sandra W Cardoso, Josphat Kosgei, Karen J Vigil, Ta Thi Dieu Ngan, Unoda Chakalisa, Stephanie Caruso, Kenneth E Sherman, Kristen M Marks

Faculty, Staff and Student Publications

Introduction: Past studies of hepatitis B vaccines in people with HIV (PWH) have shown mixed results about improving responses with increases in dose or dose frequency, leading to inconsistent guidelines and practice. We examined vaccine series completion and revaccinations in PWH lacking a seroprotective response.

Methods: Hepatitis B vaccination histories were evaluated as a retrospective study in 561 participants of A5379 trial (NCT04193189). Individuals in 41 sites in Africa, Asia, South America, and the United States qualified for the trial with antibody titers below the seroprotective level (< 10 mIU/mL) despite past hepatitis B vaccinations. The primary measure of interest was the number of vaccines in the past vaccination records.

Results: Of the 1098 trial candidates, 561 (51%) did not …