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COVID-19

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Full-Text Articles in Medicine and Health Sciences

A Pandemic Of Division: Finding Justice At Work In Challenging Times, Catherine L. Fisk Jan 2023

A Pandemic Of Division: Finding Justice At Work In Challenging Times, Catherine L. Fisk

University of San Francisco Law Review

No abstract provided.


The Prevalence Of Covid-19 Infection In Patients Having Autoimmune Or Chronic Inflammatory Rheumatic Diseases, Wessam Eissa Hamed Jan 2023

The Prevalence Of Covid-19 Infection In Patients Having Autoimmune Or Chronic Inflammatory Rheumatic Diseases, Wessam Eissa Hamed

Journal of Medicine in Scientific Research

Objective : Patients who suffer from immune-mediated or chronic inflammatory rheumatic diseases show a varying likelihood of getting hospital-diagnosed COVID-19. This study helps to search the individual risk factors involved in COVID-19 susceptibility and to provide a basis to develop a better preventive recommendation to rheumatic patients. Methods: We conducted a retrospective cohort analysis with patients being monitored and followed up in Mataria Teaching Hospital`s rheumatology department. We compared newly updated datasets of adult rheumatology patients with positive PCR tests for COVID-19 that is conducted in the hospital and identified as having chronic inflammatory arthritis (IA), autoimmune or immune-mediated disease …


For The Good Of The People: An Interpretive Analysis Of Chinese Volunteerism In The Critical Matter Of Care At The Start Of The Pandemic, Fan Li, Chunyun Gu, Yanqun Hu, Roxanne Vandermause, Anne F. Fish, Zehui Zhou, Xiaodan Yuan, Qianqian Zhou, Junya Zhu, Qingqing Lou Jan 2023

For The Good Of The People: An Interpretive Analysis Of Chinese Volunteerism In The Critical Matter Of Care At The Start Of The Pandemic, Fan Li, Chunyun Gu, Yanqun Hu, Roxanne Vandermause, Anne F. Fish, Zehui Zhou, Xiaodan Yuan, Qianqian Zhou, Junya Zhu, Qingqing Lou

Nursing Faculty Works

Purpose: China employed a unique volunteerism system where health care providers outside of Hubei Province, the epicentre, travelled to reverse the devastation wrought by coronavirus disease 2019 (COVID-19) at its global onset. The aim is to study the unique circumstances of Chinese volunteerism in the context of continuing pandemic threats, specifically exploring the experiences of 20 Chinese nurse and physician volunteers fighting COVID-19 during the outbreak. Methods: Interviews were done through video calling. Results: Using content analysis with a hermeneutic perspective, emerging patterns showed the ways in which China’s particular manifestation of volunteerism teaches us how to engage global threats …


An Acute Respiratory Distress Syndrome Drug Development Collaboration Stimulated By The Virginia Drug Discovery Consortium, John S. Lazo, Ruben M.L. Colunga-Biancatelli, Pavel A. Solopov, John D. Catravas Jan 2023

An Acute Respiratory Distress Syndrome Drug Development Collaboration Stimulated By The Virginia Drug Discovery Consortium, John S. Lazo, Ruben M.L. Colunga-Biancatelli, Pavel A. Solopov, John D. Catravas

Bioelectrics Publications

The genesis of most older medicinal agents has generally been empirical. During the past one and a half centuries, at least in the Western countries, discovering and developing drugs has been primarily the domain of pharmaceutical companies largely built upon concepts emerging from organic chemistry. Public sector funding for the discovery of new therapeutics has more recently stimulated local, national, and international groups to band together and focus on new human disease targets and novel treatment approaches. This Perspective describes one contemporary example of a newly formed collaboration that was simulated by a regional drug discovery consortium. University of Virginia, …


Changes In Severity Of Diabetes At Diagnosis Following The Onset Of The Sars-Cov-2 Pandemic, Annelise King Jan 2023

Changes In Severity Of Diabetes At Diagnosis Following The Onset Of The Sars-Cov-2 Pandemic, Annelise King

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

During the SARS-CoV-2 pandemic it was seen that diabetes was a risk factor for severe COVID-19. The objective of this study is to assess the severity of diabetes at diagnosis during the COVID-19 pandemic compared to pre-pandemic to see how the pandemic and SARS-CoV-2 infection impacted the severity of diabetes. This study used University of Kentucky electronic health records of 13,794 patients who developed diabetes. The majority of patients were female, white non-Hispanic, 65+, and living in an urban area. There were differences seen between the COVID-19 positive and negative cohorts in the DKA and HbA1c variables, with …


Covid-19 Vaccine Acceptance, Hesitancy, And Refusal Among Educators In Spring Of 2021, Jenifer O'Brien Jan 2023

Covid-19 Vaccine Acceptance, Hesitancy, And Refusal Among Educators In Spring Of 2021, Jenifer O'Brien

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The COVID-19 pandemic provided unprecedented vaccine development and deployment. Educators were among the first non-healthcare occupations to become eligible for the vaccine, and were an early predictor of vaccine hesitancy especially among educated females. By the spring of 2021, 87% of teachers had received at least one dose of the COVID-19 vaccine. Among those who expressed hesitancy, no defining demographic factors were found. Those who expressed hesitancy commonly cited a rushed vaccine development process and fear of long term side effects as reasons against vaccination.


Experiences With Covid-19 Stress Among Hispanic/Latino Farmworkers, Brenda Berumen-Flucker, Hadiza Galadima, Sylvia Shangani, Michele Kekeh, Muge Akpinar-Elci Jan 2023

Experiences With Covid-19 Stress Among Hispanic/Latino Farmworkers, Brenda Berumen-Flucker, Hadiza Galadima, Sylvia Shangani, Michele Kekeh, Muge Akpinar-Elci

Community & Environmental Health Faculty Publications

BACKGROUND: Hispanics/Latinos, particularly those that identify as foreign-born, are overrepresented in the agricultural sector in the U.S. Over the course of the COVID-19 pandemic, this subpopulation of farmworkers was recognized as an invaluable group of essential workers unable to implement COVID-19 protections.

METHODS: Previously validated COVID-19 stress scale measures were identified, adapted, and translated to collect COVID-19 stress data from Hispanic/Latino agricultural workers in two heavily agricultural counties in northeastern North Carolina. Participants were recruited using purposive convenience sampling. Data collection took place from June to November of 2021.

RESULTS: The majority of Hispanic/Latino agricultural workers surveyed reported experiencing worries …


Lessons Learned From Interdisciplinary Efforts To Combat Covid-19 Misinformation: Development Of Agile Integrative Methods From Behavioral Science, Data Science, And Implementation Science, Sahiti Myneni, Paula Cuccaro, Sarah Montgomery, Vivek Pakanati, Jinni Tang, Tavleen Singh, Olivia Dominguez, Trevor Cohen, Belinda Reininger, Lara S Savas, Maria E Fernandez Jan 2023

Lessons Learned From Interdisciplinary Efforts To Combat Covid-19 Misinformation: Development Of Agile Integrative Methods From Behavioral Science, Data Science, And Implementation Science, Sahiti Myneni, Paula Cuccaro, Sarah Montgomery, Vivek Pakanati, Jinni Tang, Tavleen Singh, Olivia Dominguez, Trevor Cohen, Belinda Reininger, Lara S Savas, Maria E Fernandez

Faculty, Staff and Student Publications

BACKGROUND: Despite increasing awareness about and advances in addressing social media misinformation, the free flow of false COVID-19 information has continued, affecting individuals' preventive behaviors, including masking, testing, and vaccine uptake.

OBJECTIVE: In this paper, we describe our multidisciplinary efforts with a specific focus on methods to (1) gather community needs, (2) develop interventions, and (3) conduct large-scale agile and rapid community assessments to examine and combat COVID-19 misinformation.

METHODS: We used the Intervention Mapping framework to perform community needs assessment and develop theory-informed interventions. To supplement these rapid and responsive efforts through large-scale online social listening, we developed a …


Poisson Regression Model With Application To Wastewater Surveillance Under A Threshold Linear Mixed Model For Covid-19 Sensitivity Rates, Norou Diawara, Hueiwang Anna Jeng, Kyle Curtis, Raul Gonzalez, Nancy Welch, Cynthia Jackson, Rekha Singh, David Jurgens, Sasanka Adikari, Omotomilola Jegede Jan 2023

Poisson Regression Model With Application To Wastewater Surveillance Under A Threshold Linear Mixed Model For Covid-19 Sensitivity Rates, Norou Diawara, Hueiwang Anna Jeng, Kyle Curtis, Raul Gonzalez, Nancy Welch, Cynthia Jackson, Rekha Singh, David Jurgens, Sasanka Adikari, Omotomilola Jegede

Mathematics & Statistics Faculty Publications

A Threshold Linear Mixed Model (TLMM) has been developed to identify specific thresholds based on wastewater SARS-CoV-2 viral concentrations, which reflect COVID-19 cases. The thresholds can guide decisions regarding public health responses and prevention measures. To assess the practical application of TLMM, a simple simulation was conducted using a sample size of 100 and 500 replications. The simulation allowed for comparing parameter estimators by assessing bias and standard deviation and the root of the mean square error. The model and estimation procedures were applied to reported wastewater and clinic data to test its application for real-world scenarios. Our results demonstrated …


Evaluation Of Wic Online Ordering During The Covid-19 Pandemic: Evidence From An Oklahoma Grocery Store Chain, Qi Zhang, Junzhou Zhang, Kayoung Park, Chuanyi Tang Jan 2023

Evaluation Of Wic Online Ordering During The Covid-19 Pandemic: Evidence From An Oklahoma Grocery Store Chain, Qi Zhang, Junzhou Zhang, Kayoung Park, Chuanyi Tang

Community & Environmental Health Faculty Publications

The COVID-19 pandemic is worsening the disparities in food access in the United States. As consumers have been increasingly using grocery online ordering services to limit their exposure to the COVID-19 virus, participants of federal nutrition assistance programs lack the online benefit redemption option. With the support of the US Department of Agriculture (USDA), retailers are pilot-testing online food benefit ordering in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). By combining the Oklahoma WIC administrative data, the online ordering data from a grocery store chain in Oklahoma, and the COVID-19 data in Oklahoma, this study examines …


A Rare Case Of Covid Encephalitis In A Vaccinated Patient, Christian Pena, Hari Movva, Hector Arredondo, Alberto Pena, Erik Hinojosa, Michael Rotko, Jorge Nadal, Michelle Lopez Jan 2023

A Rare Case Of Covid Encephalitis In A Vaccinated Patient, Christian Pena, Hari Movva, Hector Arredondo, Alberto Pena, Erik Hinojosa, Michael Rotko, Jorge Nadal, Michelle Lopez

MEDI 9331 Scholarly Activities Clinical Years

Background and Purpose: SARS-CoV-2 infection is known to cause primarily respiratory symptoms, however, neurological disorders such as anosmia and stroke have been seen. Encephalitis is a rare complication of COVID-19 with a reported incidence of less than 1%¹. Most patients develop both COVID-19 symptoms and encephalitis symptoms during the same period¹. In addition, the majority of reports are from patients with no prior vaccination. Here, we present a case of encephalitis 2 weeks after mild COVID-19 in a fully vaccinated male.

Case Presentation: A 68-year-old Hispanic male was brought to the ED due to new onset gaze deviation, generalized tonic …


Workplace Aggression Against Healthcare Workers In A Spanish Healthcare Institution Between 2019 And 2021: The Impact Of The Covid-19 Pandemic, Aitor Díaz, Mireia Utzet, Joan Mirabent, Pilar Diaz, Jose Maria Ramada, Consol Serra, Fernando G Benavides Jan 2023

Workplace Aggression Against Healthcare Workers In A Spanish Healthcare Institution Between 2019 And 2021: The Impact Of The Covid-19 Pandemic, Aitor Díaz, Mireia Utzet, Joan Mirabent, Pilar Diaz, Jose Maria Ramada, Consol Serra, Fernando G Benavides

Faculty, Staff and Student Publications

OBJECTIVES: Describe the incidence of first aggressions among healthcare workers (HCWs) before and during the COVID-19 pandemic in a Spanish healthcare institution, according to workers' socio-occupational characteristics and analyze the impact of the pandemic on it.

METHODS: A cohort involving HCWs who worked in the institution for at least 1 week each year from 1 January 2019 to 31 December 2021. Adjusted relative risks (aRR) were estimated using generalized estimating equations and negative binomial models to calculate the differences in WPA between the different time periods. All analyses were stratified by gender.

RESULTS: Among women, the incidence was 6.8% (6.0; …


Plasma Enzymatic Activity, Proteomics And Peptidomics In Covid-19-Induced Sepsis: A Novel Approach For The Analysis Of Hemostasis, Fernando Dos Santos, Joyce B Li, Nathalia Juocys, Rafi Mazor, Laura Beretta, Nicole G Coufal, Michael T Y Lam, Mazen F Odish, Maria Claudia Irigoyen, Anthony J O'Donoghue, Federico Aletti, Erik B Kistler Jan 2023

Plasma Enzymatic Activity, Proteomics And Peptidomics In Covid-19-Induced Sepsis: A Novel Approach For The Analysis Of Hemostasis, Fernando Dos Santos, Joyce B Li, Nathalia Juocys, Rafi Mazor, Laura Beretta, Nicole G Coufal, Michael T Y Lam, Mazen F Odish, Maria Claudia Irigoyen, Anthony J O'Donoghue, Federico Aletti, Erik B Kistler

Faculty, Staff and Student Publications

Introduction: Infection by SARS-CoV-2 and subsequent COVID-19 can cause viral sepsis. We investigated plasma protease activity patterns in COVID-19-induced sepsis with bacterial superinfection, as well as plasma proteomics and peptidomics in order to assess the possible implications of enhanced proteolysis on major protein systems (e.g., coagulation). Methods: Patients (=4) admitted to the intensive care units (ICUs) at the University of California, San Diego (UCSD) Medical Center with confirmed positive test for COVID-19 by real-time reverse transcription polymerase chain reaction (RT-PCR) were enrolled in a study approved by the UCSD Institutional Review Board (IRB# 190699, Protocol #20-0006). Informed consent was obtained …


Trem-1, Trem-2 And Their Association With Disease Severity In Patients With Covid-19, Ruyue Fan, Zuowang Cheng, Zhisheng Huang, Ying Yang, Na Sun, Bin Hu, Peibin Hou, Bo Liu, Chuanjun Huang, Shuai Liu Jan 2023

Trem-1, Trem-2 And Their Association With Disease Severity In Patients With Covid-19, Ruyue Fan, Zuowang Cheng, Zhisheng Huang, Ying Yang, Na Sun, Bin Hu, Peibin Hou, Bo Liu, Chuanjun Huang, Shuai Liu

Faculty, Staff and Student Publications

BACKGROUND: Delayed diagnosis and inadequate treatment caused by limited biomarkers are associated with the outcomes of COVID-19 patients. It is necessary to identify other promising biomarkers and candidate targets for defining dysregulated inflammatory states.

METHODS: The triggering receptors expressed on myeloid cell (TREM)-1 and TREM-2 expression from hospitalized COVID-19 patients were characterized using ELISA and flow cytometry, respectively. Their correlation with disease severity and contrast with the main clinical indicators were evaluated.

RESULTS: Increased expression of soluble TREM-1 and TREM-2 in the plasma of COVID-19 patients was found compared to the control group. Moreover, membrane-bound TREM-1 and TREM-2 expression was …


Non-Invasive Brain Stimulation For Fatigue In Post-Acute Sequelae Of Sars-Cov-2 (Pasc), Kelly Santana, Eduardo França, João Sato, Ana Silva, Maria Queiroz, Julia De Farias, Danniely Rodrigues, Iara Souza, Vanessa Ribeiro, Egas Caparelli-Dáquer, Antonio L Teixeira, Leigh Charvet, Abhishek Datta, Marom Bikson, Suellen Andrade Jan 2023

Non-Invasive Brain Stimulation For Fatigue In Post-Acute Sequelae Of Sars-Cov-2 (Pasc), Kelly Santana, Eduardo França, João Sato, Ana Silva, Maria Queiroz, Julia De Farias, Danniely Rodrigues, Iara Souza, Vanessa Ribeiro, Egas Caparelli-Dáquer, Antonio L Teixeira, Leigh Charvet, Abhishek Datta, Marom Bikson, Suellen Andrade

Faculty, Staff and Student Publications

BACKGROUND: and purpose: Fatigue is among the most common persistent symptoms following post-acute sequelae of Sars-COV-2 infection (PASC). The current study investigated the potential therapeutic effects of High-Definition transcranial Direct Current Stimulation (HD-tDCS) associated with rehabilitation program for the management of PASC-related fatigue.

METHODS: Seventy patients with PASC-related fatigue were randomized to receive 3 mA or sham HD-tDCS targeting the left primary motor cortex (M1) for 30 min paired with a rehabilitation program. Each patient underwent 10 sessions (2 sessions/week) over five weeks. Fatigue was measured as the primary outcome before and after the intervention using the Modified Fatigue Impact …


Characteristics Of Pediatric Covid-19 Infections And The Impact Of Influenza And Covid-19 Vaccinations During The First Two Years Of The Pandemic, Mahmoud Ali, Lynette Phillips, David C Kaelber, Hulya Bukulmez Jan 2023

Characteristics Of Pediatric Covid-19 Infections And The Impact Of Influenza And Covid-19 Vaccinations During The First Two Years Of The Pandemic, Mahmoud Ali, Lynette Phillips, David C Kaelber, Hulya Bukulmez

Faculty, Staff and Student Publications

The data regarding the demographics of SARS-CoV-2 in the pediatric population has been published based on several single-center experiences or on metanalyses over short time frames. This article reports data on the demographics of pediatric patients with COVID-19 on a global scale using the TriNetX COVID-19 Research Network. In addition, we examined the risk of COVID-19 infection in relation to the body mass index (BMI) category and the protective value of influenza and COVID-19 immunization against COVID-19 infection. The incidence of COVID-19 infection was higher in the younger age group (≤6 years old), but no gender differences. The incidence of …


Community Organization Perspectives On Covid-19 Vaccine Hesitancy And How They Increased Covid-19 Vaccine Confidence: A Canadian Immunization Research Network, Social Sciences And Humanities Network Study, Sarah Ashfield, Lorie Donelle Phd, Rn, Fcan, Gina Uppal, Michael A. Bauer Jan 2023

Community Organization Perspectives On Covid-19 Vaccine Hesitancy And How They Increased Covid-19 Vaccine Confidence: A Canadian Immunization Research Network, Social Sciences And Humanities Network Study, Sarah Ashfield, Lorie Donelle Phd, Rn, Fcan, Gina Uppal, Michael A. Bauer

Publications

BACKGROUND: COVID-19 vaccines play a critical role in reducing the morbidity and mortality associated with SARS-CoV-2 infection and despite vaccine availability, disparities in COVID-19 vaccine uptake among Canadian subgroups exist. Community organizations are uniquely situated to relay important vaccine messaging around all vaccines, understand components of vaccine hesitancy, and facilitate vaccine uptake within the communities they serve. The objective of this research was to solicit community organizations perspectives specific to COVID-19 vaccines and explore strategies of increasing vaccine uptake within their communities. METHODS: A qualitative focus group study was held in the spring of 2021 with 40 community organizations from …


An Investigation Of Media Reports Of Digital Surveillance Within The First Year Of The Covid-19 Pandemic, Leigha Comer, Lorie Donelle Phd, Rn, Fcan, Marionette Ngole, Jacob J. Shelley, Anita Kothari, Maxwell Smith, James M. Shelley, Saverio Stranges, Brad Hiebert, Jason Gilliland, Tommy Cooke, Jodi Hall, Jed Long Jan 2023

An Investigation Of Media Reports Of Digital Surveillance Within The First Year Of The Covid-19 Pandemic, Leigha Comer, Lorie Donelle Phd, Rn, Fcan, Marionette Ngole, Jacob J. Shelley, Anita Kothari, Maxwell Smith, James M. Shelley, Saverio Stranges, Brad Hiebert, Jason Gilliland, Tommy Cooke, Jodi Hall, Jed Long

Publications

INTRODUCTION: The COVID-19 pandemic prompted a surge in digital public health surveillance worldwide, with limited opportunities to consider the effectiveness or impact of digital surveillance. The news media shape public understanding of topics of importance, contributing to our perception of priority issues. This study investigated news media reports published during the first year of the pandemic to understand how the use and consequences of digital surveillance technologies were reported on. METHODS: A media content analysis of 34 high- to low-income countries was completed. The terms "COVID-19," "surveillance," "technologies," and "public health" were used to retrieve and inductively code media reports. …


Use Of Digital Technologies For Public Health Surveillance During The Covid-19 Pandemic: A Scoping Review, Lorie Donelle Phd, Rn, Fcan, Leigha Comer, Brad Hiebert, Jodi Hall, Jacob J. Shelley, Maxwell J. Smith, Anita Kothari, Jacquelyn Burkell, Saverio Stranges, Tommy Cooke, James M. Shelley, Jason Gilliland, Marionette Ngole, Danica Facca Jan 2023

Use Of Digital Technologies For Public Health Surveillance During The Covid-19 Pandemic: A Scoping Review, Lorie Donelle Phd, Rn, Fcan, Leigha Comer, Brad Hiebert, Jodi Hall, Jacob J. Shelley, Maxwell J. Smith, Anita Kothari, Jacquelyn Burkell, Saverio Stranges, Tommy Cooke, James M. Shelley, Jason Gilliland, Marionette Ngole, Danica Facca

Publications

Throughout the COVID-19 pandemic, a variety of digital technologies have been leveraged for public health surveillance worldwide. However, concerns remain around the rapid development and deployment of digital technologies, how these technologies have been used, and their efficacy in supporting public health goals. Following the five-stage scoping review framework, we conducted a scoping review of the peer-reviewed and grey literature to identify the types and nature of digital technologies used for surveillance during the COVID-19 pandemic and the success of these measures. We conducted a search of the peer-reviewed and grey literature published between 1 December 2019 and 31 December …


Access To Prenatal Care And Mental Health In Pregnant Women During Covid-19: A Systematic Review, Chloe Feezel, Marin Kahoun, Kaija Kunttu Jan 2023

Access To Prenatal Care And Mental Health In Pregnant Women During Covid-19: A Systematic Review, Chloe Feezel, Marin Kahoun, Kaija Kunttu

Williams Honors College, Honors Research Projects

COVID-19 affected the world in many ways. Pregnant women were greatly impacted by a change in their access to prenatal care, from in-person care to telehealth methods, and social support being limited by social isolation. Compared with prevalence of anxiety and depression in pregnant women pre-COVID-19, pregnant women during COVID-19 reported higher levels of anxiety and depression symptoms due to the stress of circumstantial changes. The purpose of this systematic review is to review and critically appraise the evidence about access to prenatal care and mental health in pregnant women during the COVID-19 pandemic. The following PICOT formatted question will …


Effects Of The Covid-19 Pandemic On Emergency Department Triage Nurses' Response To Patients With Potential Acute Coronary Syndrome, John R. Blakeman, Holli A. Devon, Stephen J. Stapleton, Myoungjin Kim, Ann L. Eckhardt Jan 2023

Effects Of The Covid-19 Pandemic On Emergency Department Triage Nurses' Response To Patients With Potential Acute Coronary Syndrome, John R. Blakeman, Holli A. Devon, Stephen J. Stapleton, Myoungjin Kim, Ann L. Eckhardt

Faculty Publications - Mennonite College of Nursing

Background: The COVID-19 pandemic added challenges to patient assessment and triage in the emergency department (ED).

Objective: To describe the effects of the COVID-19 pandemic on ED triage nurse decisions for patients with potential ACS.

Methods: This was a secondary analysis of data from a descriptive, electronic, survey-based study. Participants were asked two questions: whether the COVID-19 pandemic had affected their triage and/or assessment practices for patients with potential ACS and if so, how. Descriptive statistics were used to compare characteristics of participants. A qualitative descriptive approach was used to analyze responses to the open-ended questions about the pandemic’s effect …


Long-Term Kidney Function Recovery And Mortality After Covid-19-Associated Acute Kidney Injury: An International Multi-Centre Observational Cohort Study, Byom W. L. Tan, Bryce W. Q. Tan, Kee Yuan Ngiam, The Consortium For Clinical Characterization Of Covid-19 By Ehr (4ce) Jan 2023

Long-Term Kidney Function Recovery And Mortality After Covid-19-Associated Acute Kidney Injury: An International Multi-Centre Observational Cohort Study, Byom W. L. Tan, Bryce W. Q. Tan, Kee Yuan Ngiam, The Consortium For Clinical Characterization Of Covid-19 By Ehr (4ce)

Markey Cancer Center Faculty Publications

Background While acute kidney injury (AKI) is a common complication in COVID-19, data on post-AKI kidney function recovery and the clinical factors associated with poor kidney function recovery is lacking.

Methods A retrospective multi-centre observational cohort study comprising 12,891 hospitalized patients aged 18 years or older with a diagnosis of SARS-CoV-2 infection confirmed by polymerase chain reaction from 1 January 2020 to 10 September 2020, and with at least one serum creatinine value 1–365 days prior to admission. Mortality and serum creatinine values were obtained up to 10 September 2021.

Findings Advanced age (HR 2.77, 95%CI 2.53–3.04, p < 0.0001), severe COVID-19 (HR 2.91, 95%CI 2.03–4.17, p < 0.0001), severe AKI (KDIGO stage 3: HR 4.22, 95%CI 3.55–5.00, p < 0.0001), and ischemic heart disease (HR 1.26, 95%CI 1.14–1.39, p < 0.0001) were associated with worse mortality outcomes. AKI severity (KDIGO stage 3: HR 0.41, 95%CI 0.37–0.46, p < 0.0001) was associated with worse kidney function recovery, whereas remdesivir use (HR 1.34, 95%CI 1.17–1.54, p < 0.0001) was associated with better kidney function recovery. In a subset of patients without chronic kidney disease, advanced age (HR 1.38, 95%CI 1.20–1.58, p < 0.0001), male sex (HR 1.67, 95%CI 1.45–1.93, p < 0.0001), severe AKI (KDIGO stage 3: HR 11.68, 95%CI 9.80–13.91, p < 0.0001), and hypertension (HR 1.22, 95%CI 1.10–1.36, p = 0.0002) were associated with post-AKI kidney function impairment. Furthermore, patients with COVID-19-associated AKI had significant and persistent elevations of baseline serum creatinine 125% or more at 180 days (RR 1.49, 95%CI 1.32–1.67) and 365 days (RR 1.54, 95%CI 1.21–1.96) compared to COVID-19 patients with no AKI.

Interpretation COVID-19-associated …


Experiences And Attitudes Regarding The Availability And Usage Of Telemedicine Services Among Providers During A Pandemic, Keya Gaston Brooks Jan 2023

Experiences And Attitudes Regarding The Availability And Usage Of Telemedicine Services Among Providers During A Pandemic, Keya Gaston Brooks

Walden Dissertations and Doctoral Studies

Telehealth became a prominent fixture in the way healthcare was delivered during COVID-19. Providers were forced to offer telehealth as an optional mode of care. Although little research was available, studies about the experiences and attitudes of providers regarding their intention and willingness to use telemedicine before the pandemic was exiguous. The purpose of this study was to understand providers perception and use behavior patterns regarding the acceptance and adoption of telemedicine during the pandemic. Data collected from the COVID-19 Healthcare Coalition Telehealth Impact Survey was used to help characterize the experiences and attitudes of providers regarding telehealth utilization during …


Long-Term Psychological Adaptation Of U.S. Human Resource Personnel In Response To The Covid-19 Pandemic, Samantha Ann Denson Jan 2023

Long-Term Psychological Adaptation Of U.S. Human Resource Personnel In Response To The Covid-19 Pandemic, Samantha Ann Denson

Walden Dissertations and Doctoral Studies

Previous research indicated that the COVID-19 pandemic negatively impacted employee psychological outcomes in various workforce sectors. Although research showed that U.S. human resource (HR) employees experienced unique occupational challenges during the pandemic, the literature did not explore pandemic-related psychological outcomes in this population. This quantitative survey-based study included a purposive sample of 294 U.S. HR professionals to explore the pandemic’s impact on their psychological well-being. The transactional model of stress and coping served as the theoretical framework to understand the independent effects of appraisal, meaning-based coping, and coping efforts on psychological well-being. A mediation analysis was used to understand the …


Occupational Stress In Long Term Care In Georgia And Virginia During The Covid-19 Pandemic, Lacountess Renee Hooks Jan 2023

Occupational Stress In Long Term Care In Georgia And Virginia During The Covid-19 Pandemic, Lacountess Renee Hooks

Walden Dissertations and Doctoral Studies

Nursing staff working in long-term care settings experience high levels of occupational stress related to many factors that can lead to poor outcomes for the nursing staff and the residents. In 2020, the World Health Organization declared severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as COVID-19, a pandemic which over the course of 3 years, has added an additional source of work-related stress for long-term care nursing staff. This quantitative cross-sectional study was guided by the job demand-control-support model to explore perceived stress and nursing stress among nursing staff working in the long-term care setting in Georgia and …


Age, Race/Hispanic Origin, And Covid-19 Mortality Among Sickle Cell Disease Patients In The United States, Joe Lamont Ndula Jan 2023

Age, Race/Hispanic Origin, And Covid-19 Mortality Among Sickle Cell Disease Patients In The United States, Joe Lamont Ndula

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic remains a global health challenge, with 6.7 million deaths worldwide as of January 2023. It has illuminated the health iniquities in underserved communities and populations like those with sickle cell disease (SCD). Researchers have associated the COVID-19 outcome among SCD patients in other regions of the globe. The purpose of this retrospective cross-sectional observational study was to investigate the relationship between age, race/Hispanic origin, and COVID-19 mortality among persons with SCD in the United States from January 2020 to March 2021. The Krieger ecosocial theory of disease distribution framed the study. Data were drawn from an existing …


Evaluating U.S. Household Telemedicine Use In Primary Care Settings, Robert Osobase Jan 2023

Evaluating U.S. Household Telemedicine Use In Primary Care Settings, Robert Osobase

Walden Dissertations and Doctoral Studies

AbstractThe COVID-19 pandemic's arrival in the United States restricted access and use of telemedicine in primary care providers (PCPs) settings. Addressing this issue is crucial since telemedicine is a confirmed method of encouraging patients and PCPs to promote quality health care. This quantitative study investigated the association between age, gender, and race, and PCPs offering telemedicine and U.S. household adults using telemedicine during COVID-19 pandemic in 2021. The Donabedian framework, which considers aspects of an organization's structure, process, and outcome, served as the study's foundation, incorporating age, race, and gender as independent variables, and PCPs and US adults as dependent …


Residential Segregation And County-Level Covid-19 Booster Coverage In The Deep South: Surveillance Report And Ecological Study, Chengbo Zeng, Jiajia Zhang Ph.D., Zhenlong Li, Xiaowen Sun, Huan Ning, Xueying Yang, Sharon Weissman, Bankole Olatosi Ph.D., Xiaoming Li Ph.D. Jan 2023

Residential Segregation And County-Level Covid-19 Booster Coverage In The Deep South: Surveillance Report And Ecological Study, Chengbo Zeng, Jiajia Zhang Ph.D., Zhenlong Li, Xiaowen Sun, Huan Ning, Xueying Yang, Sharon Weissman, Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Background: COVID-19 had a greater impact in the Deep South compared with other regions in the United States. While vaccination remains a top priority for all eligible individuals, data regarding the progress of booster coverage in the Deep South and how the coverage varies by county and age are sparse. Despite existing evidence of racial and ethnic disparities in COVID-19 vaccinations at the individual level, there is an urgent need for evidence at the population level. Such information could highlight vulnerable communities and guide future health care policy-making and resource allocation.

Objective: We aimed to evaluate county-level COVID-19 booster coverage …


“To Live In The Body Of A Survivor ”: Unique And Cumulative Disaster Exposure And Mental Health In A Sample Of Hurricane Katrina Survivors, Noelle Serino Jan 2023

“To Live In The Body Of A Survivor ”: Unique And Cumulative Disaster Exposure And Mental Health In A Sample Of Hurricane Katrina Survivors, Noelle Serino

Public Health Theses

Introduction: Fueled by the escalation of climate change, weather-related disasters are increasing in frequency and severity. Existing research has documented the extensive harm induced by such disasters, yet few studies have examined how individuals’ psychological well-being fares when exposed to multiple, diverse threats, including other weather-related and public health disasters (e.g., COVID-19). As such, the present study explores posttraumatic and psychological distress in the context of unique and cumulative disaster exposure.Methods: The data utilized for this study came from the Resilience in Survivors of Katrina (RISK) Project. The sample was comprised of 381 predominantly Non-Hispanic Black (84.5%) women who experienced …


Sprinting In A Marathon: Nursing Staff And Nurse Leaders Make Meaning Of Practicing In Covid-19 Devoted Units Pre-Vaccine, Natalie S. Mcandrew, William E. Rosa, Kaylen M. Moore, Jacqueline Christianson, Tala Abuzahra, Megann Mussatti, Colleen Mccracken, Amy R. Newman, Kelly Calkins, Susan Breakwell, Katie Klink, Jill L. Guttormson Jan 2023

Sprinting In A Marathon: Nursing Staff And Nurse Leaders Make Meaning Of Practicing In Covid-19 Devoted Units Pre-Vaccine, Natalie S. Mcandrew, William E. Rosa, Kaylen M. Moore, Jacqueline Christianson, Tala Abuzahra, Megann Mussatti, Colleen Mccracken, Amy R. Newman, Kelly Calkins, Susan Breakwell, Katie Klink, Jill L. Guttormson

College of Nursing Faculty Research and Publications

Objective

To describe the lived experience of nursing staff and nurse leaders working in COVID-19 devoted units (intensive care or medical unit) prior to vaccine availability.

Research Design

Qualitative phenomenological design with a focus group approach.

Methods

The study team recruited a convenience sample of nursing staff (nurses, and nursing assistants/nurse technicians) and nurse leaders (managers, assistant nurse managers, clinical nurse specialists, and nurse educators) at an academic medical center in the midwestern United States. Focus groups and individual interviews were conducted to encourage participants to describe their (1) experiences as nursing professionals, (2) coping strategies, and (3) perspectives about …