Medicine and Health Sciences Commons^™

Covid-19 Pandemic And Racial And Ethnic Disparities In Long-Term Nursing Home Stay Or Death Following Hospital Discharge, Laurent G Glance, Karen E Joynt Maddox, Patricia W Stone, Jingjing Shang, E Yoko Furuya, Ashley M Chastain, Ji Won Lee, Bridget Morse-Karzen, Andrew W Dick

2020-Current year OA Pubs

IMPORTANCE: Long-term nursing home stay or death (long-term NH stay or death), defined as new long-term residence in a nursing home or death following hospital discharge, is an important patient-centered outcome.

OBJECTIVE: To examine whether the COVID-19 pandemic was associated with changes in long-term NH stay or death among older adults with sepsis, and whether these changes were greater in individuals from racial and ethnic minoritized groups.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used patient-level data from the Medicare Provider Analysis and Review File, the Master Beneficiary Summary File, and the Minimum Data Set. Community-dwelling individuals aged at least …

Delivering Guideline-Concordant Care For Patients With High-Risk Hpv And Normal Cytologic Findings, Jasmin A Tiro, Jacquelyn M Lykken, Patricia M Chen, Cheryl R Clark, Sarah Kobrin, Jessica Chubak, Sarah Feldman, Claudia Werner, Steven J Atlas, Michelle I Silver, Jennifer S Haas

2020-Current year OA Pubs

IMPORTANCE: As US health care systems shift to human papillomavirus (HPV)-based cervical cancer screening, more patients are receiving positive high-risk non-16/18 genotype HPV results and negative for intraepithelial lesion or malignancy (NILM) cytological findings. Risk-based management guidelines recommend 2 consecutive negative annual results to return to routine screening.

OBJECTIVE: To quantify patterns of surveillance testing and associated outcomes for patients after an HPV-positive results and NILM cytologic findings.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study analyzed patients in the METRICS (Multi-level Optimization of the Cervical Cancer Screening Process in Diverse Settings and Populations) cohort of the PROSPR II (Population-Based Research …

Brain Age Modeling And Cognitive Outcomes In Young Adults With And Without Sickle Cell Anemia, Andria L Ford, Slim Fellah, Yan Wang, Kira Unger-Levinson, Maria Hagan, Martin N Reis, Amy Mirro, Josiah B Lewis, Chunwei Ying, Kristin P Guilliams, Melanie E Fields, Hongyu An, Allison A King, Yasheng Chen

2020-Current year OA Pubs

IMPORTANCE: Both sickle cell anemia (SCA) and socioeconomic status have been associated with altered brain structure and cognitive disability, yet precise mechanisms underlying these associations are unclear.

OBJECTIVE: To determine whether brains of individuals with and without SCA appear older than chronological age and if brain age modeling using brain age gap (BAG) can estimate cognitive outcomes and mediate the association of socioeconomic status and disease with these outcomes.

DESIGN, SETTING, AND PARTICIPANTS: In this cross-sectional study of 230 adults with and without SCA, individuals underwent brain magnetic resonance imaging (MRI) and cognitive assessment. Brain age was estimated using DeepBrainNet, …

T Helper 2 Cell-Directed Immunotherapy Eliminates Precancerous Skin Lesions, Tomonori Oka, Neel S. Raval, Mary Tabacchi, Lynn A. Cornelius, Et Al.

2020-Current year OA Pubs

The continuous rise in skin cancer incidence highlights an imperative for improved skin cancer prevention. Topical calcipotriol-plus-5-fluorouracil (calcipotriol-plus-5-FU) immunotherapy effectively eliminates precancerous skin lesions and prevents squamous cell carcinoma (SCC) in patients. However, its mechanism of action remains unclear. Herein, we demonstrate that calcipotriol-plus-5-FU immunotherapy induces T helper type 2 (Th2) immunity, eliminating premalignant keratinocytes in humans. CD4+ Th2 cells were required and were sufficient downstream of thymic stromal lymphopoietin cytokine induction by calcipotriol to suppress skin cancer development. Th2-associated cytokines induced IL-24 expression in cancer cells, resulting in toxic autophagy and anoikis followed by apoptosis. Calcipotriol-plus-5-FU immunotherapy was dependent …

Meta-Ea: A Gene-Specific Combination Of Available Computational Tools For Predicting Missense Variant Effects, Panagiotis Katsonis, Olivier Lichtarge

Faculty, Staff and Students Publications

Computational methods for estimating missense variant impact suffer from inconsistent performance across genes, which poses a major challenge for their reliable use in clinical practice. While ensemble scores leverage multiple prediction methods to enhance consistency, the overrepresentation of certain genes in the training data can bias their outcomes. To address this critical limitation, we propose a gene-specific ensemble framework trained on reference computational annotations rather than on clinical or experimental data. Accordingly, we generate Meta-EA ensemble scores that achieve comparable performance to the top individual predicting method for each gene set. Incorporating the effects of splicing and the allele frequency …

N-Linked Fucosylated Glycans Are Biomarkers For Prostate Cancer With A Neuroendocrine And Metastatic Phenotype, Joseph E Ippolito, Hani Nakhoul, Cody Weimholt, Elena Nunez, Nikolaos A Trikalinos, Et Al.

2020-Current year OA Pubs

Prostate cancer is a heterogeneous disease with a spectrum of pathology and outcomes ranging from indolent to lethal. Although there have been recent advancements in prognostic tissue biomarkers, limitations still exist. We leveraged matrix-assisted laser desorption/ionization imaging of formalin-fixed, paraffin embedded prostate cancer specimens to determine if N-linked glycans expressed in the extracellular matrix of lethal neuroendocrine prostate cancer were also expressed in conventional prostate adenocarcinomas that were associated with poor outcomes. We found that N-glycan fucosylation was abundant in neuroendocrine prostate cancer as well as adenocarcinomas at the time of prostatectomy that eventually developed recurrent metastatic disease. Analysis of …

Correlation Of Physical Activity With Vasomotor, Psychosocial, And Physical Symptoms Of Menopausal Women In A Rural Area Of Pati Regency, Indonesia, Shovia Nurul Hidayati, Winarni Winarni

Journal of Asian Midwives (JAM)

Background: Menopause often brings vasomotor, psychosocial, and physical symptoms that challenge women's well-being, yet physical activity offers a promising avenue for relief. Physical activity can improve a person's quality of life. Menopausal women in Pegandan village have varying physical activity and menopausal symptoms but it is currently unknown whether they are correlated. This study investigated the correlation between physical activity and vasomotor, psychosocial, and physical symptoms among menopausal women.
Methods: The study employed a cross-sectional design involving 47 menopausal women from Posyandu Lansia in Pegandan village, Pati regency, Indonesia. They were selected by simple random sampling. Participants' measurements for physical …

Diagnosing Pulmonary Embolism Utilizing Computed Tomography, Abigail Nolan

Student Research Poster Presentations 2025

The purpose of this project is to explore the evolution of computed tomography (CT) technology in diagnosing a pulmonary embolism (PE) and highlight its superiority over other imaging modalities in modern medical practice. A pulmonary embolism (PE) is a life-threatening condition caused by a blood clot blocking blood flow in the lungs. It is one of the leading causes of sudden death and has severe complications. Rapidly and accurately diagnosing PE is critical for effective treatment and improved patient outcomes. Computed tomography pulmonary angiography (CTPA) has become the gold standard for diagnosing PE due to its high sensitivity, specificity, and …

Lusaka's Colonial Legacy: Town Planning, Public Health, And The Making Of A Segregated City, 1913–1963. A Study Of Power, Inequality, And Urban Development, Wamburakwao J. Sapao

Zambia Social Science Journal

This paper explores the intersection of town planning and public health policy in Lusaka, Northern Rhodesia (now Zambia), during the colonial period (1913–1963), which was a time of significant urban growth and transformation. British colonial authorities adapted Ebenezer Howard's Garden City principles to design and manage Lusaka, but these measures perpetuated spatial control, segregation, and social engineering, thus exacerbating racial and socio-economic disparities. By analysing secondary and primary sources, including planning ordinances, zoning regulations, and public health policies, this study reveals how these measures shaped the city's development and reinforced inequalities. Despite colonial intentions for a white settler-city, Lusaka evolved …

The Role Of Maternal Position During The Second Stage Of Labor On Reducing Perineal Injury: An Integrative Review, Ericka L. Dalton, Tabatha Ruth Erlandson

All Electronic Theses and Dissertations

Introduction: Perineal lacerations remain a common occurrence amongst vaginal deliveries. While there are some recommendations for supportive techniques throughout the literature, position is typically not included in these. Perineal trauma can have a lasting effect on the individual and increase health care costs. The purpose of this review is to identify what birthing positions are most effective at preventing perineal injury.

Methods: A formalized search of the literature was conducted via PubMed, CINAHL, Google Scholar, and SCOPUS databases. Of the 344 articles identified, 22 original studies met the inclusion and exclusion criteria for this review. A literature matrix and quality …

Facilitators And Barriers To Interprofessional Collaboration Between Physicians And Midwives: An Integrative Review, Kathy D. Lambright, Anesha E. Martin

All Electronic Theses and Dissertations

Introduction: Early models of interprofessional collaborative care suggest that when there is a collaboration between midwives and physicians, the outcomes for mothers and babies are improved. The purpose of this integrative review of the relevant literature is to identify the facilitators and barriers to collaborative relationships between physicians and midwives.

Methods: A keyword search was done using the Science Direct, PubMed, and CINAHL databases. Inclusion criteria were that they must be original research, identify facilitators and barriers in interprofessional collaborative relationships, and include healthcare professionals involved in maternity care. The database search yielded a total of 348 articles, which were …

Freestanding Birth Centers-Safety And Efficacy Related To Maternal And Neonatal Outcomes: An Integrative Review, Nicole Lynn Muzik, Casey Renee Workman

All Electronic Theses and Dissertations

Introduction: The goal of this literature review is to determine the safety of community birth by evaluating if low-risk pregnant women at term, who deliver in the community setting, specifically at freestanding birth centers, have comparable or lower maternal and neonatal morbidity and mortality outcomes, than low-risk women who deliver at an in-hospital birthing facility.

Methods: The authors of this integrative review retrieved original research articles from computerized databases (Nursing and Allied Health, PubMed, and CINAHL), as well as online journal hand searching, followed by cited reference searching. A total of 48 articles underwent a full-text review, and a total …

The Health Impact Of Clinical Training On Nursing Students In Cambodia, Felicia Kim Yee, Kimberly Aguilar Mondragon

Nursing | Senior Theses

Background: Clinical training presents significant challenges for nursing students worldwide, particularly evident in developing countries like Cambodia, where these difficulties are intensified by a lack of training, resources, and health issues like stress and fatigue. Many students struggle without adequate guidance, forcing them to navigate complex clinical environments independently. These factors not only impact students’ confidence and academic performance, but also their health and well-being. Through this study, we can gain insight into nursing in a developing country that hasn’t been widely studied, contributing to global nursing research. Purpose: The purpose of this study is to explore the health impact …

Psychological Impact Of Ulcerative Colitis On Pregnancy And Postpartum Period, Stephanie C. Carver

Nursing | Senior Theses

Background

Ulcerative colitis (UC) poses significant challenges during pregnancy, affecting both physical and mental health. While the physiological effects of UC during pregnancy are well documented, less is known about its impact on maternal mental health. This study aims to investigate the psychological effects of UC on pregnant women, focusing on stress levels, postpartum depression (PPD) incidence, and the role of multidisciplinary care in improving mental health outcomes.

Objective

The primary objective of this research proposal is to evaluate the psychological impact of UC during pregnancy and determine whether disease activity increases the risk of PPD and stress. A secondary …

Improving Maternal Mental Health: The Role Of Specialized Support For Queer Women With Postpartum Depression, Dan-Tam Pham

Nursing | Senior Theses

Queer women face disproportionately high rates of postpartum depression compared to heterosexual and cisgender individuals. Studies showed that queer women face heightened mental health challenges, including higher rates of depression and anxiety due to factors like discrimination, limited support systems, and negative healthcare experiences. There is a need for culturally competent, LGBTQ+-affirming interventions to improve maternal mental health outcomes; despite the health disparities faced by this population, research on specialized postpartum interventions is limited, revealing gaps in effective mental health care for queer mothers. The key search terms for the articles used in the study included: postpartum depression, queer women, …

The Diagnosis And Treatment Of Prostate Cancer, Lilly Bernard

Student Research Poster Presentations 2025

The purpose of this project is to discuss all aspects of prostate cancer, with a focus on radiation therapy as a treatment option. An overview of the disease is provided, including statistics, risk factors, symptoms, the process of diagnosis, treatment options, and a case study. Prostate cancer is the most common cancer in men and second leading cause of cancer death in the United States, making it widespread and deadly. This means that it is important to understand as much as possible about the disease in order to achieve the best outcomes possible. The project lists experiences from patients who …

Pediatric Approaches For Magnetic Resonance Imaging, Ashley Riha

Student Research Poster Presentations 2025

Abstract

Pediatric magnetic resonance imaging is often challenging due to the lack of cooperation and the inability to fully understand the expectations required for the examination. Children are often restless and may have difficulty remaining still for a long period of time. This can lead to motion artifacts and compensate diagnostic value. Due to these reoccurring challenges, there are several strategies to help relax the nerves of pediatric patients. Sedatives can be administered to relax the patients and assist in cooperation during the long scanning times. However, sedation safety, dosage, and patient monitoring is essential when administering medication. Alternative approaches …

The Effects Of Vestibular Rehabilitation Interventions On Patients With Parkinson's Disease: A Systematic Review, Christopher Farrell, Eduard Turner

Student Research Poster Presentations 2025

Background: Vestibular rehabilitation is known to be effective in the treatment of vestibular dysfunction. While patients with Parkinson's disease have both central and peripheral vestibular dysfunction, there is little information regarding the efficacy of vestibular rehabilitation for the treatment of these individuals.

Study Design: Systematic Review

Purpose: The purpose of this systematic review was to examine the effects of vestibular rehabilitation in patients with Parkinson’s disease.

Results: The interventions identified in this study resulted in improved Berg Balance Scale (BBS) and Dizziness Handicap Questionnaire (DHI) scores.

Conclusion: Vestibular rehabilitation improves balance and subjective dizziness in patients with Parkinson’s disease.

Transpersonal Philosophy Grows Up: A Clarification Of Ken Wilber’S Most Recent Updates To His Theoretical Framework, Ritske Rensma

International Journal of Transpersonal Studies Advance Publication Archive

The fact that there are multiple phases to Ken Wilber’s theoretical development has been widely recognized, with Wilber himself arguing that his works can be divided into four distinct phases (1983/2001). Students of Wilber’s work later added a fifth and final phase, which is said to begin in 2001. What has received hardly any scholarly attention, however, is the fact that Wilber still made major changes to his theoretical framework several years after the beginning of phase 5 in Integral Spirituality (2006), and that it is only after the publication of this book that his thinking really reaches a steady …

Unitlessness: Highlighting The Trans-Discursive Qualities Of Nondualism And Implications For Psychological Terminology, Christian U. Krägeloh

International Journal of Transpersonal Studies Advance Publication Archive

Nondual awareness has recently gained increased interest in broader psychological research. In meditation contexts, it reflects the dissolution of subject and object, while in Maha_ya_na Buddhism, practitioners aim to develop insight that leads to awareness of nonduality in everyday-life situations. Traditionally, teaching of nondualism employed paradoxes to prompt nonconceptual inquiry into reconciling dualistic contradictions. To offer an approach to communicate nondualism to a modern audience of psychology researchers, the framework of unitlessness is introduced here, which differentiates between linguistic characteristics (units) and experiential phenomena (unity), both within an enveloping ineffability (unitlessness). This type of nondualism is trans-discursive, as it acknowledges …

The Stages Of Change Model As Applied To Cluttering: Next Steps, Kathleen Scaler Scott, Samantha Delmar, Sarah Hardy, Emma Schaedler, Erica Scheinberg, Kateri Grice, Brenna Field, Margaret Koester, Emma Maley, Kayla Montemarano, Brooke Price

Student Research Poster Presentations 2025

This study is based upon the Transtheoretical/Stages of Change model. The model has been studied in adults with a variety of health behaviors such as addiction (Prochaska, 1999; Prochaska &DiClemente, 1984) and has been applied to current stuttering treatment (Zebrowski et al., 2021) to assess readiness for change. The Stages of Change model consists of five stages: precontemplation, contemplation, preparation, action, and maintenance. Whenever considering making a change, as one would do as part of speech therapy, clients may move in and out of these stages. Therefore, it is important to understand what stage a client is in in order …

In Vivo Evaluation Of Novel Nanoparticles And Repurposed Pharmaceuticals To Combat Antimicrobial Resistance, Sarah E. Evans

Theses, Dissertations and Capstones

In a 2019 report by the Centers for Disease Control and Prevention (CDC), infections resistant to antibiotic treatment amount to about three million infections and 48,000 deaths. Antimicrobial resistance is an escalating global threat as existing antibiotics lose efficacy over time. The project described is focused on partnering with pharmaceutical researchers and producers to test new nanoparticle-based or repurposed compounds. The central hypothesis of this thesis is that pharmaceutical formulations such as nanoparticles may provide a cost-effective means of combating the emerging antimicrobial resistance. The nanoparticle compounds allowed for a wide range of customization for the pharmaceutical design, since the …

Editorial: Frontiers In The Midlands Society Of Physiological Sciences (2023-2024), Sathish Kumar Natarajan, Hong Zheng, Surabhi Chandra, Harold D. Schultz, William C.W. Chen

Journal Articles: Cellular & Integrative Physiology

No abstract provided.

Growing South Dakota (Winter 2025), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Native Plant Initiative on a mission
[Page] 4 Gees give back
[Page] 7 Christensen named assistant dean
[Page] 8 Fennell honored in plant biology
[Page] 9 New ag communication faculty
[Page] 10 SDSU Extension awards
[Page] 12 Veterinary medicine class welcomed
[Page] 13 Coulter honored
[Page] 14 National beef award winners
[Page] 15 Department celebrates 100 years
[Page] 16 Southeast Research Farm growing
[Page] 18 Saving the flock
[Page] 22 Energize conference inspires
[Page] 24 BeefSD helping producers
[Page] 25 SDSU Extension retirements
[Page] 26 New food safety testing service
[Page] 27 Bringing back bison
[Page] 28 Jackrabbits …

Effects Of Push-In Occupational Therapy Services In Kindergarten On Writing Foundations, Heather A. Hyndman

Occupational Therapy Doctorate Capstone Projects

Background: According to the Compensation & Workforce Survey, 24.89% of occupational therapy practitioners (OTPs) work in schools (AOTA, 2023). This researcher has worked in a public-school setting for over 20 years, and her caseload continues to grow each year, doubling in the past 10 years. Handwriting difficulties account for most referrals for this researcher.

Purpose: The purpose of this research was to determine if an occupational therapy (OT) led fine motor intervention small group along with push-in occupational therapy services during literacy instruction would improve kindergarten students’ handwriting.

Theoretical Framework: Motor learning theory is applicable to teaching handwriting. This …

Minimally Invasive Non-Expansile Tubular Extradural Posterior Fossa Decompression (Minted Technique) For The Management Of Chiari I.5 Malformation: Historical Overview Of Surgical Techniques, Technical Note, Proof Of Concept, Illustrative Case And Case Series. Lesser Is Better, José Alberto Israel Romero Rangel, Manuel Eduardo Soto García, Sergio Soriano Solís, Carlos Raúl Rangel Morales, Gerson Reyes Rodríguez, José Antonio Soriano Sánchez

Archives of Neurosurgery

BACKGROUND: Chiari's Malformation surgical treatment has significantly changed since the "classical" technique description by Gardner (1950). It is probably the most commonly performed approach, even when multiple techniques are available because no substantial changes nor any clear surgical objectives have been made. OBJECTIVE: To demonstrate a new cutting-edge surgical technique mastering the advantage of each surgical procedure ever described in the history of Chiari's Malformation establishing three critical points in surgical technique: clear patient-specific surgical goals, dynamic posterior fossa reconstruction, and extradural occipitoatlantal dense-adhesions release. METHODS: A comprehensive review of historically described approaches, proof of concept of surgical technique in …

The Nondual Realization Of Advaita Vedanta Does Not Support A Psychological Theory Of Consciousness, Glenn Hartelius

International Journal of Transpersonal Studies Advance Publication Archive

Advaita Vedanta is seen as something of an authoritative source for nondual philosophies and theories of consciousness that postulate a pure featureless awareness at the base of mental experience. These approaches deviate from both the lineage-based teachings of Advaita Vedanta and the necessary standards of science, constructing compromises that fall short of traditional fidelity and psychological rigor. Dialogues between psychology and Advaita Vedanta need to delineate clearly between a sensate phenomenology of experience and spiritual interpretations that may be implicit within experiential descriptions.

The Head, The Heart, And The Human: A Developmental Cascade Perspective Of Adults With Dextro-Transposition Of The Great Arteries, Alexandra Brooke Roseman

Selected Full-Text Dissertations 2020-

As survival rates for individuals with complex congenital heart disease (CHD), such as dextro-Transposition of the Great Arteries (d-TGA), increase, there is a growing need to examine neurocognitive and psychosocial challenges from a lifespan perspective. However, research often overlooks the integration of these factors, despite evidence from other chronic illness populations suggesting their interplay influences psychosocial functioning in adulthood. This study assessed psychosocial maturity in emerging adults with d-TGA and explored its relationship with executive functioning (EF) and social cognition (SC) longitudinally. Data were drawn from the Boston Circulatory Arrest Study (BCAS) cohort at age 16 (n = 80) and …

Beyond The Numbers: A Qualitative Exploration Of Patient Perspectives On Postpartum Care And Maternal Mortality, Kristen A. Waters

Master of Public Health Program Student Publications

Introduction

Montgomery County faces one of Ohio's highest maternal mortality rates, with notable disparities by race. Despite their importance in reducing maternal deaths, up to 40% of women nationwide do not attend a postpartum care (PPC) visit. While well researched guidelines exist regarding the content and timing of PPC visits, there is a lack of patient perspective on this topic, specifically in the Black-identifying population in an area with a significant burden of maternal mortality.

Methods

Semi-structured interviews and focus group sessions were conducted with 31 participants of maternal health community events in Dayton, OH. Participants were asked their opinions …

The Integration Of Video Recording In Health Assessment Simulation To Improve Feedback Quality, Stephanie Bork, Meredith Deegan, Allison Gregory

School of Nursing Publications

Introduction

Simulation-based learning is integral in preparing nursing students, especially graduate-level nurse practitioner (NP) students. Simulation bridges the gap between theory and practice, providing a safe space for students to practice clinical skills, communication, and develop appropriate clinical judgment and reasoning before delivering care to patients in healthcare settings. Video recording in the simulated environment enhances educators’ ability to assess student competency and performance. During a faculty-observed simulation, it can be challenging to deliver consistent, meaningful, and competency-based feedback to each student. This project aims to integrate Echo360 video recording in graduate health assessment simulation to enhance the quality of …