Medicine and Health Sciences Commons^™

Comparison Of Clinical Outcomes After Medial Patellofemoral Ligament Reconstruction With Allograft Versus Autograft: A Matched-Cohort Analysis, Jeffrey Henstenburg, Josuhu Pezzulo, Dominic Farronato, Emma Johnson, John Bodnar, Philip Petrucelli, Christopher Dodson, Kevin Freedman, Steven Cohen, Sommer Hammoud

Rothman Institute Papers

BACKGROUND: Disruption of the medial patellofemoral ligament (MPFL) may lead to recurrent lateral patellar dislocation and patellofemoral chondral injury. Despite significant previous work investigating numerous performance parameters, the optimal graft choice for MPFL reconstruction for patellar instability remains unclear.

PURPOSE: To compare functional outcomes scores, subjective recurrent instability, and revision rates between autograft and allograft in MPFL reconstruction.

STUDY DESIGN: Cohort study; Level of evidence, 3.

METHODS: Patients who underwent MPFL reconstruction with autograft between 2013 and 2018 were identified. A 2:1 comparison group of patients who underwent MPFL reconstruction with allograft was matched by sex, age (±3 years), and …

Medical Imaging Dataset Management Leveraging Deep Learning Frameworks In Breast Cancer Screening, Inchan Hwang

Dissertations

In the domain of Computer-Aided Diagnosis (CADx) for breast cancer diagnosis through mammography, prevailing models have traditionally been trained and validated using old film-based mammography. However, contemporary U.S. hospital practices involve the utilization of Full Field Digital Mammography (FFDM), offering more detailed images captured at various angles than old film-scanned mammography. Despite this shift, the existing body of research predominantly focuses on old-film based datasets, the implications of FFDM for CADx systems have not been understood. This dissertation addresses the issues emerged from FFDM such as data augmentation between old film-based set and new FFDM whether they are more effective …

Analysis Of Mothers Participation In Bringing Their Toddlers To Posyandu In The Banda Raya Community Health Center Area, Banda Aceh City In 2023, Susi Hariyanti, Risky Kusuma Hartono

Cities and Urban Development Journal

Background: Integrated Service Post (Posyandu) is a community-sourced health center that belongs to the community and is integrated into the lufe and culture of the community. Lack of community participation in the utilization of Posyandu is one of the problems that hamper the implementation of health services through Posyandu. Domain factors of low participation are from family support, knowledge and attitudes of mothers of toddlers. This support D/S coverage (D is the number of toddlers weighed and S is the number of all toddlers in the area) which is not meeting the national target of 80%.

Aims: This study aims …

Maternal Decision Making And Children’S Nutritional Status: Evidence From Indonesia, Nadia Roswita, Teguh Dartanto

Jurnal Ekonomi Kependudukan dan Keluarga

Indonesia is encountering consecutive health problems caused by malnutrition. The latter poses long-term effects on children’s development. As this issue continue its prominence, using linear regression and binary logistic with time lag to analyze data from Indonesia Family Life Survey (IFLS) in 2007 and 2014 shall support the analysis of issue. Previous results from the models indicated that maternal decision-making in their share of food expenditure has a weak correlation for stunted children's experience. However, this study revealed different results. It suggested that involvement in from men in nutritional knowledge, skills, and financial backing to advance women's roles contributes to …

Pengaruh Karakteristik Rumah Tangga Terhadap Kejadian Kematian Maternal Di Pulau Papua, Intan Putri Utami, Yuliagnis Transver Wijaya

Jurnal Ekonomi Kependudukan dan Keluarga

Maternal health and life during pregnancy, childbirth, and the postpartum period are very important in determining the growth and future development of the birth generation. SDG indicators express the global seriousness of this effort, aiming to reduce the maternal mortality ratio (MMR) to less than 70 per 100,000 live births by 2030. However, according to the Long Form SP2020, Indonesia still has 189 deaths per 100,000 live births. Papua and West Papua are the two provinces with the worst MMR achievements, with 565 and 343 deaths per 100,000 live births, respectively. Therefore, this research will provide general overview and identify …

A Mixed Methods Exploration Of Young Women's Agency And Mental Health During Covid-19 In Low-Income Communities In Mumbai, India, Marie A Brault, Melissa F Peskin, Anastasia N Jones, Amrita Saikia, Rinchen O Bhutia, Sai Sammitha Cheruvu, Vaishali M Jagtap, Rajendra Singh, Poornima Nair, Rajesh Vedanthan, Sten H Vermund, Shubhada Maitra

Faculty, Staff and Student Publications

Introduction: Adolescent girls and young women (AGYW) in India face additional health inequities compared to their male peers, as gender norms constrain agency for prevention and self-care. The onset of the COVID-19 pandemic and associated lockdowns deepened health inequities and often worsened mental health, but the impacts on agency are unclear. This exploratory sequential mixed methods paper examined mental health and COVID-19 elements that exacerbated or mitigated adverse consequences for AGYW in low-income communities in Mumbai.

Methods: We conducted semi-structured interviews with AGYW (aged 15-25 years; N = 60) and adults (parents, healthcare providers, community-based organization representative; N = 30). …

Molecular Insights Into Propylthiouracil As A Thyroid Peroxidase Inhibitor: A Computational Study Approach, Dwi Anita Suryandari, Luluk Yunaini, Hadi Sunaryo, Khaerunissa Anbar Istiadi, Irandi Putra Pratomo

Indonesian Journal of Medical Chemistry and Bioinformatics

Thyroid peroxidase (TPO) is a crucial enzyme in the biosynthesis of thyroid hormones, catalyzing the iodination of tyrosine residues in thyroglobulin and the coupling of iodotyrosines to form thyroxine (T4) and triiodothyronine (T3). Propylthiouracil (PTU) is an antithyroid drug commonly used to manage hyperthyroidism by inhibiting TPO. Understanding the molecular interactions between TPO and PTU can provide insights into the inhibitory mechanisms and guide the design of more effective antithyroid medications. Objective: This study aims to elucidate the binding interactions between TPO and PTU through molecular docking, providing a detailed understanding of how PTU inhibits TPO activity. Methods: …

Iatrogenic Atrial Septal Defect After Mitraclip Transcatheter Edge-To-Edge Repair: To Close Or Not To Close??, Mariem Abdelsalam, Raghad Younus, Lamis F Abdalla, Abdelkader Almanfi

The Texas Heart Institute Journal

The evolution of percutaneous procedures that use transseptal puncture to treat left-sided structural heart disease has led to the emergence of iatrogenic atrial septal defects as a potential complication. These defects can result in hemodynamic decompensation and worsening clinical outcomes. Some iatrogenic atrial septal defects require immediate closure, others do not. This case report presents 2 patients who underwent transcatheter edge-to-edge mitral valve repair with transseptal puncture and required iatrogenic atrial septal defect closure (1 immediate and 1 delayed). The goal of this report is to highlight iatrogenic atrial septal defect assessment and the possible need for closure after transseptal …

Abstract Book Of The 16th Indonesian Occupational Medicine Update (Iomu)

Occupational and Environmental Medicine Journal of Indonesia

Jakarta, Indonesia, 2nd March to 4th March 2024

Mckenzie Exercise For Reducing Low Back Pain Complaints In Office Worker: An Evidence-Based Case Report, Bonnie Medana Pahlavie, Dewi S. Soemarko, Indah Suci Widyahening

Occupational and Environmental Medicine Journal of Indonesia

Background:

Low back pain (LBP) is pain that is felt in the lower back area, namely between the corners of the lowest ribs and the lower buttocks (lumbar or lumbo-sacral area) and can be local pain or radiate to the upper thighs/legs or both. Low back pain is a 10% debilitating condition that results in a change in life expectancy due to disability. Low back pain is not a malignancy and is a self-limiting condition, but patients always seek treatment to reduce the severity of their symptoms. Chronic Low Back Pain can alter lifestyle and increase the rate of prolonged …

Treatment Of Large Intracranial Aneurysms Using The Woven Endobridge (Web): A Propensity Score-Matched Analysis, Basel Musmar, Hamza Adel Salim, Nimer Adeeb, Assala Aslan, Bahaa Aljeradat, Jose Danilo Bengzon Diestro, Rachel M Mclellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann V Lay, Adrien Guenego, Leonardo Renieri, Nicole M Cancelliere, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Justin E Vranic, Charlotte Chung, Mohamed M Salem, Ivan Lylyk, Paul M Foreman, Jay A Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad U Hafeez, Joshua Catapano, Muhammad Waqas, Vincent M Tutino, Mohamed K Ibrahim, Marwa A Mohammed, M Ozgur Ozates, Giyas Ayberk, James D Rabinov, Yifan Ren, Clemens M Schirmer, Mariangela Piano, Anna L Kühn, Caterina Michelozzi, Stéphanie Elens, Robert M Starke, Ameer Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie T Nawka, Marios Psychogios, Christian Ulfert, Julian Spears, Brian T Jankowitz, Jan-Karl Burkhardt, Ricardo A Domingo, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Amir Essibayi, Sunil A Sheth, Gary Spiegel, Rabih Tawk, Boris Lubicz, Pietro Panni, Ajit S Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph J Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan Brook, David Altschul, Andrew F Ducruet, Felipe C Albuquerque, Robert W Regenhardt, Christopher J Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A Aziz-Sultan, Stavropoula I Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo H Cuellar-Saenz, Pascal M Jabbour, Vitor Mendes Pereira, Aman B Patel, Adam A Dmytriw

Faculty, Staff and Student Publications

The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence …

A Clinical Comparison With The Flattening Free Filter Technique For Lung Stereotactic Body Radiotherapy Using Functional Lung Planning, Addison Gucwa

Masters Projects

Abstract

Introduction

Lung cancer remains the leading cause of cancer incidence and mortality worldwide. Advances in stereotactic body radiation therapy have demonstrated survival rates comparable to surgery, however, they come with a higher risk of developing radiation pneumonitis. The aim of this study was to explore the possibility of minimizing the risk of lung toxicities after stereotactic body radiation therapy to lung tumors with the use of functional lung planning and flattening filter free beams.

Materials and Methods

This retrospective study analyzed treatment planning data from ten patients previously treated with SBRT for inoperable lung tumors. Functional lung volumes were …

Extraordinary Phase Transition Revealed In A Van Der Waals Antiferromagnet, Xiaoyu Guo, Wenhao Liu, Jonathan Schwartz, Suk Hyun Sung, Dechen Zhang, Makoto Shimizu, Aswin L N Kondusamy, Lu Li, Kai Sun, Hui Deng, Harald O Jeschke, Igor I Mazin, Robert Hovden, Bing Lv, Liuyan Zhao

Faculty, Staff and Student Publications

While the surface-bulk correspondence has been ubiquitously shown in topological phases, the relationship between surface and bulk in Landau-like phases is much less explored. Theoretical investigations since 1970s for semi-infinite systems have predicted the possibility of the surface order emerging at a higher temperature than the bulk, clearly illustrating a counterintuitive situation and greatly enriching phase transitions. But experimental realizations of this prediction remain missing. Here, we demonstrate the higher-temperature surface and lower-temperature bulk phase transitions in CrSBr, a van der Waals (vdW) layered antiferromagnet. We leverage the surface sensitivity of electric dipole second harmonic generation (SHG) to resolve surface …

Phase Ii Study Of Talazoparib In Advanced Cancers With Brca1/2, Dna Repair, And Pten Alterations, Sarina A Piha-Paul, Chieh Tseng, Cheuk Hong Leung, Ying Yuan, Daniel D Karp, Vivek Subbiah, David Hong, Siqing Fu, Aung Naing, Jordi Rodon, Milind Javle, Jaffer A Ajani, Kanwal P Raghav, Neeta Somaiah, Gordon B Mills, Apostolia M Tsimberidou, Xiaofeng Zheng, Ken Chen, Funda Meric-Bernstam

Faculty, Staff and Student Publications

Cancer cells with BRCA1/2 deficiencies are sensitive to poly (ADP-ribose) polymerase (PARP) inhibitors. We evaluated the efficacy of talazoparib in DNA-Damage Repair (DDR)-altered patients. In this phase II trial, patients were enrolled onto one of four cohorts based on molecular alterations: (1) somatic BRCA1/2, (2) other homologous recombination repair pathway, (3) PTEN and (4) germline BRCA1/2. The primary endpoint was a clinical benefit rate (CBR): complete response, partial response or stable disease ≥24 weeks. 79 patients with a median of 4 lines of therapy were enrolled. CBR for cohorts 1-4 were: 32.5%, 19.7%, 9.4% and 30.6%, respectively. PTEN mutations correlated …

Phase Ii Study Of Talazoparib In Advanced Cancers With Brca1/2, Dna Repair, And Pten Alterations, Sarina A Piha-Paul, Chieh Tseng, Cheuk Hong Leung, Ying Yuan, Daniel D Karp, Vivek Subbiah, David Hong, Siqing Fu, Aung Naing, Jordi Rodon, Milind Javle, Jaffer A Ajani, Kanwal P Raghav, Neeta Somaiah, Gordon B Mills, Apostolia M Tsimberidou, Xiaofeng Zheng, Ken Chen, Funda Meric-Bernstam

Faculty, Staff and Student Publications

Cancer cells with BRCA1/2 deficiencies are sensitive to poly (ADP-ribose) polymerase (PARP) inhibitors. We evaluated the efficacy of talazoparib in DNA-Damage Repair (DDR)-altered patients. In this phase II trial, patients were enrolled onto one of four cohorts based on molecular alterations: (1) somatic BRCA1/2, (2) other homologous recombination repair pathway, (3) PTEN and (4) germline BRCA1/2. The primary endpoint was a clinical benefit rate (CBR): complete response, partial response or stable disease ≥24 weeks. 79 patients with a median of 4 lines of therapy were enrolled. CBR for cohorts 1-4 were: 32.5%, 19.7%, 9.4% and 30.6%, respectively. PTEN mutations correlated …

Adaptation Of The Protein Misfolding Cyclic Amplification (Pmca) Technique For The Screening Of Anti-Prion Compounds, Katherine Do, Rebeca Benavente, Celso S G Catumbela, Uffaf Khan, Carlos Kramm, Claudio Soto, Rodrigo Morales

Faculty, Staff and Student Publications

Prion diseases result from the misfolding of the physiological prion protein (PrPC) to a pathogenic conformation (PrPSc). Compelling evidence indicates that prevention and/or reduction of PrPSc replication are promising therapeutic strategies against prion diseases. However, the existence of different PrPSc conformations (or strains) associated with disease represents a major problem when identifying anti-prion compounds. Efforts to identify strain-specific anti-prion molecules are limited by the lack of biologically relevant high-throughput screening platforms to interrogate compound libraries. Here, we describe adaptations to the protein misfolding cyclic amplification (PMCA) technology (able to faithfully replicate PrPSc strains) that increase its throughput to facilitate the …

A Comparison Of Tracheal Intubation Using Direct Laryngoscope And Video Laryngoscope In The Sellick And Trendelenburg Position With That Using Direct Laryngoscope In The Supine Sniffing Position: A Randomized Controlled Trial, Yun-Jeong Chae, Jung-Yoon Moon, Min-Gyu Lee, Han-Bum Joe

Faculty, Staff and Student Publications

Background: Tracheal intubation in the Sellick and Trendelenburg position (ST position) can prevent pulmonary aspiration but increase the difficulty of tracheal intubation. We compared tracheal intubation using video and direct laryngoscopy in the ST position with direct laryngoscopy in the supine sniffing position to evaluate the overall intubation performance. Methods: One hundred and twenty patients were randomly assigned to three groups: direct laryngoscope in the supine sniffing position (control), direct laryngoscope in the ST position (ST direct), and video laryngoscope in the ST position (ST video). The primary outcome was the intubation time; secondary outcomes included the first …

Meta-Analysis Identifies Common Gut Microbiota Associated With Multiple Sclerosis, Qingqi Lin, Yair Dorsett, Ali Mirza, Helen Tremlett, Laura Piccio, Erin E Longbrake, Siobhan Ni Choileain, David A Hafler, Laura M Cox, Howard L Weiner, Takashi Yamamura, Kun Chen, Yufeng Wu, Yanjiao Zhou

2020-Current year OA Pubs

BACKGROUND: Previous studies have identified a diverse group of microbial taxa that differ between patients with multiple sclerosis (MS) and the healthy population. However, interpreting findings on MS-associated microbiota is challenging, as there is no true consensus. It is unclear whether there is gut microbiota commonly altered in MS across studies.

METHODS: To answer this, we performed a meta-analysis based on the 16S rRNA gene sequencing data from seven geographically and technically diverse studies comprising a total of 524 adult subjects (257 MS and 267 healthy controls). Analysis was conducted for each individual study after reprocessing the data and also …

Customization Of Computed Tomography Radio-Opacity In 3d-Printed Contrast-Injectable Tumor Phantoms, Yuktesh Kalidindi, Aravinda Krishna Ganapathy, Liam Cunningham, Adriene Lovato, Brian Albers, Anup S Shetty, David H Ballard

2020-Current year OA Pubs

Medical Imaging Phantoms (MIPs) calibrate imaging devices, train medical professionals, and can help procedural planning. Traditional MIPs are costly and limited in customization. Additive manufacturing allows for customizable, patient-specific phantoms. This study examines the CT attenuation characteristics of contrast-injectable, chambered 3D-printed phantoms to optimize tissue-mimicking capabilities. A MIP was constructed from a CT of a complex pelvic tumor near the iliac bifurcation. A 3D reconstruction of these structures composed of three chambers (aorta, inferior vena cava, tumor) with ports for contrast injection was 3D printed. Desired attenuations were 200 HU (arterial I), 150 HU (venous I), 40 HU (tumor I), …

The Correlation Of Age With Thrombocytes And D-Dimer Values In Covid-19 Patients At Hospital X In Jakarta, Indonesia, Nanik Prasetyoningsih, Ascobat Gani

Kesmas

Coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, spread globally, with research indicating that prognosis severity can be assessed by thrombocyte and D-dimer levels; while, patient age serves as a mortality predictor. This study aimed to analyze the relationship between age with thrombocytes and D-dimer in COVID-19 patients. This cross-sectional study used laboratory testing samples from 667 COVID-19 patients at Hospital X in Jakarta, Indonesia, collected from August 2020 until May 2021. The data was collected using cluster random sampling and analyzed using descriptive statistics and the Chi square test (95% CI). The results showed that age and thrombocytes positively …

Systematic Review Of Factors Related To Pm2.5 Exposure On The Risk Of Type 2 Diabetes Mellitus, Rifka Putri Salma, Laila Fitria

Kesmas

Diabetes mellitus is a major public health problem in many countries, and most of them are type 2 diabetes mellitus (T2DM). Air pollution is thought to contribute to the T2DM incidence, and one of the most important pollutants is PM2.5. This study aimed to determine factors related to PM2.5 exposure and individual factors in increasing the risk of T2DM based on a systematic review. The PRISMA was used as a method of data collection and selection. Of 176 relevant articles identified and screened, 12 articles from various countries published in 2013-2021 were synthesized in this study. Results showed that long-term …

Prevention Of Tuberculosis Transmission Through Mycobacterium Tuberculosis Detection In The Air, Ni Njoman Juliasih, Eko Budi Koendhori, I Nyoman Semita

Kesmas

Tuberculosis (TB) is a dangerous and highly contagious disease. Global cases have increased since, and Indonesia is one of the countries with the highest number of TB cases. This study aimed to prevent TB transmission by analyzing air contamination. Air samples were taken from three primary health cares (PHCs) in Surabaya City, East Java Province, Indonesia, and cultured in Mycobacterium Growth Indicator Tube (MGIT) media. Of the 108 air samples collected, 36 came from the waiting room, 36 from the examination room, and 36 from the laboratory room. As a result, the waiting room (50%), examination room (16.7%), and laboratory …

Health And Environmental Pollution: A Literature Review, Elsa Yuniarti, Levi Anatolia S.M. Exposto, Indang Dewata, Fitra Arya Dwi Nugraha, Alfitri Alfitri

Kesmas

This study aimed to review various studies focusing on pollution that could adversely affect health, including sources, types, and mitigation efforts. The data used were obtained through a search on the Scopus website using the keywords "Health" AND "Pollution" from 2016 to 2023. Using these two keywords, 72 titles and abstracts of papers were successfully found. The results of this literature review were then analyzed with the assistance of NVivo 12 Pro, which grouped the findings based on their impact on health, reasons for pollution, types of pollution, and preventive measures. It was identified that the most common disease was …

Capitation Management Through Performance-Based Capitation Mechanism Of Primary Health Care In Malang, Indonesia, Ayu Tyas Purnamasari, Herlinda Dwi Ningrum, Anggi Ardhiasti, Asri Hikmatuz Zahroh

Kesmas

Primary health care (PHC) has one of the largest funding sources, capitation, which BPJS Healthcare Security transfers monthly. Capitation fund receipts were frequently insufficient due to failure to meet performance-based capitation/Kapitasi Berbasis Kinerja (KBK) targets, including for PHC in Malang City, Indonesia. This study aimed to examine the management and utilization of capitation funds through a KBK mechanism. This descriptive study used a qualitative approach supported by quantitative data. This study was conducted from July to August 2023 and purposely selected nine informants from BPJS Healthcare Security, the local health office, and PHC. The interviews were transcribed verbatim and analyzed …

Environmental Health Risk Analysis Of So2 And No2 In Kemiri Muka Village, Depok City, Indonesia, Nuansa Dwika Aulia, Budi Hartono

Kesmas

Kemiri Muka is a village in Beji Subdistrict, Depok City, Indonesia. Based on a preliminary survey conducted in one of the neighborhood units of Kemiri Muka Village, the residential had a high density of houses and was close to traditional markets, toll roads, the main road of Depok City, and landfills. This caused the air quality in the village area to decline. This study aimed to analyze risks to public health and the environment from exposure to toxic substances, SO2 and NO2, which are high in the air due to transportation on the highway and population density. The sample from …

Economic Loss Of Leptospirosis: Is It Still Appropriate To Be Tropical Neglected Zoonosis Disease?, Wahyu Pudji Nugraheni, Sinta Dewi Lestyoningrum, Ristiyanto Ristiyanto, Wahyu Gito Putro, Indah Pawitaningtyas, Syarifah Nuraini, Linta Meyla Putri, Debri Rizki Faisal, Adhista Eka Noveyani, Muhammad Agus Mikrajab

Kesmas

Leptospirosis is a tropical endemic disease that can reduce the productivity of sufferers. However, research on economic and productivity losses due to leptospirosis is rare. This study aimed to determine economic and productivity losses due to leptospirosis in the Banyumas District, Indonesia, as an endemic area. This study used a cross-sectional design and quantitative methods conducted in October 2022. Secondary data of medical records and billing information from 73 inpatients receiving treatment at a Public Hospital in the Banyumas District from February 2021 to September 2022 obtained from the hospital’s archives were used. This study examined the actual costs (direct …

Exercise To Improve Asthma Control And Lung Function In Stable Asthma: An Evidence-Based Case Report, Abdul Rois Romdhon, Andre Thadeo Abraham, Triya Damayanti

Kesmas

Asthma is a heterogeneous disease with respiratory symptoms that vary over time and intensity. Exercise-induced asthma patients are advised to avoid strenuous physical activity, which can trigger bronchospasm. However, appropriate exercise can improve asthma control and lung function in stable asthma patients. A literature search was conducted on PubMed, COCHRANE, and EMBASE databases using Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines according to the specified eligibility criteria. Those studies were critically appraised using the Oxford Critical Appraisal Tool 4.0. Four articles were selected based on the PRISMA search strategy flowchart to assess their validity, importance, and applicability. …

Multidrug-Resistant Organisms Infection On Mortality Of Burn Patients At Public Hospital X In Jakarta: A Retrospective Study, Raja Merlinda Veronica, July Kumalawati, Cleopas Martin Rumende, Leonard Nainggolan, Marcellus Simadibrata, Hamzah Shatri, Em Yunir, Aditya Wardhana, Erni Juwita Nelwan, Musfardi Rustam

Kesmas

Susceptibility to infection and increasing antibiotic resistance put burn patients at risk of developing infections caused by multidrug-resistant organisms (MDRO). This condition can progress to sepsis, increasing morbidity and mortality. This retrospective cohort study employed the medical record data of patients treated at Public Hospital X in Jakarta, Indonesia, from January 2020 to June 2022. Of 160 subjects, most were aged <60 years (82.5%) and had comorbidities (16.88%). The most common cause of burns was fire (86.25%). The use of medical devices was 90.63%, with a 14-day median length of stay. The most common gram-negative MDRO pathogens were K. pneumoniae (29.91%), Enterobacter sp (22.32%), and Acinetobacter (20.54%); 45% of patients infected with MDRO died. The bivariate analysis found an increased risk of death due to MDRO infection in burn patients (RR 1.103; 95%CI 1.004-1.211, p-value = 0.046). After adjusting for role variables (age, comorbidities, total body surface area, use of medical devices, length of stay) and from multivariate analysis, the confounding variables for MDRO infection and mortality were length of stay and age. MDRO infection increases the mortality rate in burn patients. Mortality in burn patients due to MDRO infection is greater than non-MDRO.

Data Mining Analysis With Orange In The Development Of Tuberculosis Among Diabetes Mellitus Patients, Malahayati Rusli Bintang, Adang Bachtiar, Cicilya Candi

Kesmas

Prevention and treatment of diabetes will have a positive influence on tuberculosis (TB) since people may get TB because they have diabetes mellitus (DM). Recording and reporting through the TB Information System are not run optimally because of many factors. The information system must be strengthened to be used by private health facilities. This study used secondary data from the 2013 and 2018 Indonesian Basic Health Research (IBHR). The data was analyzed univariately and analyzed further using Orange Data Mining Tools to test the screening tool model used to predict TB in diabetic individuals. The total sample in this study …

Smoking Habit At Home And Upper Respiratory Infection In Infants Aged 6-12 Months, Musfardi Rustam, Nur Pelita Sembiring, Taswir Effendy

Kesmas

Upper Respiratory Tract Infection (URI) is an acute infection caused by viruses, fungi, and bacteria. Smoking habit at home is a risk factor for URI in infants. This study aimed to determine a relationship between smoking at home and the incidence of URI in infants. This study was conducted the fourth week of February 2010 until the third week of April 2010 in Kampar District, Indonesia. This analytical study used a case-control design and cluster random sampling. The samples comprised 162 cases and 162 controls, infants aged 6-12 months. The cases were 162 infants aged 6-12 months suffering from URI …