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2024

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Full-Text Articles in Medicine and Health Sciences

Exploring Gender Variation In Medical Student Professional Identity Development: A Longitudinal Study Through The Career Eulogy Perspective, William J. Crump, Sarah M. Fisher, Ronald R. Gilley, Whitney T. Gilley, Craig Ziegler Jul 2024

Exploring Gender Variation In Medical Student Professional Identity Development: A Longitudinal Study Through The Career Eulogy Perspective, William J. Crump, Sarah M. Fisher, Ronald R. Gilley, Whitney T. Gilley, Craig Ziegler

Marshall Journal of Medicine

Background

Empathy towards patients is a key component of a physician's professional identity. In longitudinal studies at their campus, the authors of this study observed that women had higher empathy scores as measured by a standard Likert scale survey; however, the differences were insignificant in most training years.

Methods

In this larger study, the authors confirmed this finding and used a career eulogy projective exercise to explore gender differences in professional identity formation more deeply than a Likert scale score. The study included 76 medical students from all 4 years of training at a rural, regional medical school campus in …


A Case Of Herpes Zoster In An Immunocompetent 19-Year-Old Female, Martin Nguyen, Jennifer Read, Emma Filary, Aaron Mcguffin Jul 2024

A Case Of Herpes Zoster In An Immunocompetent 19-Year-Old Female, Martin Nguyen, Jennifer Read, Emma Filary, Aaron Mcguffin

Marshall Journal of Medicine

This case report describes the unusual presentation of herpes zoster in a fully vaccinated teenage patient and highlights management considerations. The patient is a 19-year-old female who presented with pain in her left lower back, side, and upper thigh for approximately 3 days, which was then followed by the eruption of a vesicular rash along the L2 dermatome consistent with herpes zoster. Herpes zoster is predominantly observed only in elderly and immunocompromised individuals, primarily due to the widespread use of the varicella-zoster virus vaccine for children since 1995, when it became part of the routine immunization schedule. However, this case …


Management Of Multiple Infantile Hemangiomas In A Preterm Infant: A Clinical Case Report, Erin Reese, Wyatt Grimm, Aaron Mcguffin Jul 2024

Management Of Multiple Infantile Hemangiomas In A Preterm Infant: A Clinical Case Report, Erin Reese, Wyatt Grimm, Aaron Mcguffin

Marshall Journal of Medicine

Infantile hemangiomas (IH), the most prevalent infantile tumor, are benign vascular tumors arising from proliferation and dysregulation of angiogenesis. Hemangiomas are present after birth and undergo 3 stages: proliferation, plateau, and involution. IH are further categorized into superficial, deep, and mixed based on skin and internal organ involvement. IH are clinically diagnosed, and treatment options include active observation, corticosteroids, beta-blockers, pingyangmycin, vincristine, or laser treatment. Complications of untreated IH include ulceration, airway obstruction, and visual obstruction at sites of enlarging lesions. While most cases are benign, there are associated complications prompting a thorough investigation and proper management. Understanding a hemangioma …


"You Are Already A Leader": Lessons For A Successful Career In Medicine, Vineet Arora Jul 2024

"You Are Already A Leader": Lessons For A Successful Career In Medicine, Vineet Arora

Marshall Journal of Medicine

Vineet Arora, MD, MAPP, addressed the Medical School class of 2024, emphasizing leadership, clear communication, advocacy, and continuous learning. She shared personal experiences, highlighting gender equity, self-care, and combating burnout. Arora affirmed the graduates’ roles as leaders dedicated to improving health and healthcare for their patients and communities.


Fatal Fatigue: Thrombotic Thrombocytopenic Purpura, Rachel K. Kitzmann Jul 2024

Fatal Fatigue: Thrombotic Thrombocytopenic Purpura, Rachel K. Kitzmann

SIU Journal of Medical Science Scholarly Works

A 75 year old female presented to the family medicine clinic with complaints of fatigue, intermittent epigastric pain, decreased appetite with associated weight loss, easy bruising, and bilateral hand tremors. Physical exam was positive for scattered bruising, but otherwise benign. Initial differential diagnoses included hypothyroidism, anemia, vitamin or mineral deficiency, sleep apnea, malignancy, and tick-borne illness. Preliminary labs were drawn in clinic. The patient presented to the Emergency Department within 2 hours of leaving the clinic due to stroke-like symptoms. Workup revealed markedly low platelets with schistocytes identified on peripheral blood smear. PLASMIC score was applied, which indicated a high …


Early Identification Of Autism Spectrum Disorder Markers In Infants Using The Infant And Motor Engagement Scale, Cesley L. Taft Jul 2024

Early Identification Of Autism Spectrum Disorder Markers In Infants Using The Infant And Motor Engagement Scale, Cesley L. Taft

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.


Implementation Of An Evidence-Based Hospital Acquired Pressure Injury Strategy In The Intensive Care Unit, Tonya C.W. Brigman Jul 2024

Implementation Of An Evidence-Based Hospital Acquired Pressure Injury Strategy In The Intensive Care Unit, Tonya C.W. Brigman

Student Scholarly Projects

Practice Problem: Hospital-acquired pressure injuries (HAPI) are a significant concern in healthcare with the most vulnerable group being the adult patients in ICUs leading to increased morbidity, longer hospital stays, and higher healthcare costs.

PICOT: In adult ICU patients (P) does the implementation of daily chlorhexidine gluconate (CHG) baths with post bath barrier cream combined with intentional turning every 2-hours (I) compared to standard skin care practices and nonintentional turning (C) reduce the incidence of hospital-acquired pressure injuries (HAPI) (O) within 10-weeks (T)?

Evidence: The project was based on the analysis of the literature published in the …


Bibliometric Analysis Of Research Trends And Novelties For Pneumonia In Children, Ariyani Lutfitasari, Fitriani Nur Damayanti, Budi Santosa, Lia Mulyanti, Umi Khasanah Jul 2024

Bibliometric Analysis Of Research Trends And Novelties For Pneumonia In Children, Ariyani Lutfitasari, Fitriani Nur Damayanti, Budi Santosa, Lia Mulyanti, Umi Khasanah

Jurnal Keperawatan Indonesia

Pneumonia is the leading cause of death among children globally, with most cases occurring in low- and middle-income nations. Pneumonia in children has been thoroughly researched in numerous countries throughout the world. However, no research performed bibliometric analyses of pneumonia in children. This study aims to use a biometric analysis to determine trends in the number of publications, the number of citations, network visualization, overlay visualization, and density visualization concerning the issue of pneumonia in children. This research method employs a systematic review with stages adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowchart. The highest …


Why Did They Fail? Investigating The Eight Invalid Dimensions Of Patient Safety Culture: Mixed Method Research, Felicia Setiawan, Ferdi Antonio Jul 2024

Why Did They Fail? Investigating The Eight Invalid Dimensions Of Patient Safety Culture: Mixed Method Research, Felicia Setiawan, Ferdi Antonio

Jurnal Keperawatan Indonesia

Resistance to adopting patient safety culture practices or technologies can hinder improvements in patient safety. This study contributes to enhancing the understanding of patient safety culture (PSC) assessment by identifying the specific factors that render some PSC dimensions invalid and offering actionable recommendations for improvement in healthcare settings. Primary data were gathered using a mixed method of explanatory sequential design, with quantitative data collection and analysis followed by qualitative data collection and analysis. The study was conducted in the leading Private Hospital XYZ, one of the private hospital groups internationally accredited with Joint Commission International with a 110-patient bed capacity. …


Self-Efficacy In Salt Consumption Among Patients Undergoing Hemodialysis, Desy Listyaningrum, Melyza Perdana, Anita Kustanti Jul 2024

Self-Efficacy In Salt Consumption Among Patients Undergoing Hemodialysis, Desy Listyaningrum, Melyza Perdana, Anita Kustanti

Jurnal Keperawatan Indonesia

Salt consumption restriction has many advantages in patients on hemodialysis (HD), but it is also very challenging for them. Self-efficacy is a crucial aspect of successful disease management. Factors related to self-efficacy have been evaluated in many countries. However, the different demographic characteristics in Indonesia may show different significant results. Understanding this problem may contribute to the development of nursing interventions and the patients’ self-management ability while undergoing HD. Hence, the present study aimed to determine the factors associated with self-efficacy for restricting salt consumption among HD patients. Altogether, 98 HD patients participated in this cross-sectional study. The Self-efficacy for …


Improving Parent And Nurse Communication Using The Lowline Model In The Cvicu, Nelli Hodorff Noor Jul 2024

Improving Parent And Nurse Communication Using The Lowline Model In The Cvicu, Nelli Hodorff Noor

DNP Projects

This project was designed to help improve family and nurse communication using the LOWLINE model in the CVICU to allow families and nurses to be on the same page and work as a team.


Implementation Of A Sickle Cell Disease Toolkit In The Emergency Department To Improve Provider Knowledge And Confidence, Kendra Paeper Jul 2024

Implementation Of A Sickle Cell Disease Toolkit In The Emergency Department To Improve Provider Knowledge And Confidence, Kendra Paeper

DNP Projects

No abstract provided.


Feasibility Of Individualized Toolkits To Reduce Childhood Obesity In A Pediatric Primary Care Setting, Molly Sexe Jul 2024

Feasibility Of Individualized Toolkits To Reduce Childhood Obesity In A Pediatric Primary Care Setting, Molly Sexe

DNP Projects

Background: Childhood obesity rates continue to rise, leading to comorbid conditions presenting in adolescence and adulthood (Durbin, 2018). Individualized toolkits focusing on various health habits have been identified as an effective intervention in pediatric primary care practices (Byrne et al., 2018; Henderson, 2021; Mead et al., 2017; Smith et al., 2021 & Wright et al., 2018). This project assessed barriers of the current obesity prevention program at a pediatric primary care clinic, Operation Get FIT. This project identified steps to revising Operation Get FIT to tailor it more to the needs and goals of the participating clinic, the providers, and …


Integration Of Depression And Anxiety Screening Among Uninsured And Underinsured Patients In A Mobile Nurse-Led Clinic, Samantha Hamm Jul 2024

Integration Of Depression And Anxiety Screening Among Uninsured And Underinsured Patients In A Mobile Nurse-Led Clinic, Samantha Hamm

DNP Projects

This quality improvement project sought to increase screening rates and referrals for pregnant and postpartum depression/ anxiety using the Edinburgh Postnatal Depression Scale (EPDS) and increase the rate of mental health referrals as a result of that screening in an underserved population /community health mobile clinic. Maternal mental health is a key public health concern. In the most recent community health needs assessment (2022-2025) in one Midwestern rural community, priority needs were identified with the top priority of building families with access to culturally competent healthcare, including access to mental health services (Central MN Alliance, 2022). Under-reporting anxiety and depression …


Knowledge And Attitudes Toward Baby-Led Weaning In Primary Care, Taylor Schreiner Jul 2024

Knowledge And Attitudes Toward Baby-Led Weaning In Primary Care, Taylor Schreiner

DNP Projects

Objective

Adequate nutrition is critical for an infant’s growth and development. Around the age of six months, most infants can begin the process of being introduced to table foods. The debate is about what method is safest for the infant, spoon-led feeding or baby-led weaning (BLW).

Methods

This project explored the beliefs, attitudes, and knowledge of both parents of infants and primary care providers (PCP) on baby-led weaning. Data were obtained through the use of pre-and post-surveys following the implementation of specific education for parents and PCPs.

Results

The findings from parents who participated would suggest that most parents who …


Online Diabetes Program Improving Nurses' Competency In School-Age Diabetes Care, Kristina Donovan Jul 2024

Online Diabetes Program Improving Nurses' Competency In School-Age Diabetes Care, Kristina Donovan

Doctor of Nursing Practice Scholarly Projects

Background: Diabetes affects over 280,000 children under 20 in the US, requiring specialized knowledge and skills for management. In a large urban school district with 54,000 students, 159 have diabetes, cared for by 158 school nurses. These nurses often struggle with the complexities of diabetes care and lack standardized training, leading to potential suboptimal care. An online diabetes education program was implemented to improve their competency, knowledge and skills, and confidence in managing diabetes in school-age children.

Methods: An asynchronous online competency-based diabetes education program to improve nurses’ competency to care for school-age children with diabetes was implemented in an …


Sealy-Jefferson Et Al. Responds To Invited Commentary By Joseph Et Al. With “Toward Naming Who And What Is Accountable For Racial Inequities In Adverse Black Maternal Mental Health”, Shawnita Sealy-Jefferson, Benita Jackson, Brittney Francis Jul 2024

Sealy-Jefferson Et Al. Responds To Invited Commentary By Joseph Et Al. With “Toward Naming Who And What Is Accountable For Racial Inequities In Adverse Black Maternal Mental Health”, Shawnita Sealy-Jefferson, Benita Jackson, Brittney Francis

Psychology: Faculty Publications

No abstract provided.


Traditional Art Dance Therapy To Reduce Stress Levels Of Elementary School Students, Shinta Restu Wibawa, Christantie Effendy, Heny Suseani Pangastuti, Ami Novianti Subagya, Eryono Budi Wijoyo, Aisya Puteri Andari, Dwi Apriliana, Qurrota Aini Zahrotu Sholikhah Jul 2024

Traditional Art Dance Therapy To Reduce Stress Levels Of Elementary School Students, Shinta Restu Wibawa, Christantie Effendy, Heny Suseani Pangastuti, Ami Novianti Subagya, Eryono Budi Wijoyo, Aisya Puteri Andari, Dwi Apriliana, Qurrota Aini Zahrotu Sholikhah

Jurnal Keperawatan Indonesia

COVID-19 pandemic has accelerated the development of new learning systems that are more student-centered. Unfortunately, elementary school students experienced stress and difficulties in adapting from face-to-face to online learning system. Online learning environment lacks in accommodating outdoor activities which are important for children. Several techniques can be applied to reduce stress, including dancing. This research aimed to examine the effectiveness of Traditional Art dance Therapy (TATA) for elementary school students in reducing stress. In this quasi-experimental research, one-group pretest-posttest design without control group was applied, involving 84 students at one elementary school in Yogyakarta , Indonesia. Students’ levels of stress …


Alternative Therapies Of The Banjar People For Children With Fevers, Esme Anggeriyane, Hamzah Hamzah, Nurhikmah Nurhikmah Jul 2024

Alternative Therapies Of The Banjar People For Children With Fevers, Esme Anggeriyane, Hamzah Hamzah, Nurhikmah Nurhikmah

Jurnal Keperawatan Indonesia

Fevers often occur in children under five years of age due to the immature formation of their immune systems. Such fevers signify that something unusual is happening in the body, often due to illness. Parents conduct various management techniques, such as medical or traditional treatments, based on their beliefs. Banjar society has a health culture known as bapidara, which is used to treat children with fevers presumably attributable to supernatural disturbances. This exploratory research aimed to discover what alternative therapies the Banjar people use to treat children with fevers. This qualitative study used a transcendental phenomenological design. Data collection was …


Ammonia Exposure Based On The Length Of Work To Lung Function Abnormalities Among Traditional Scavengers, Maulyda Shakeela Jasmine, Fajaria Nurcandra, Nayla Kamilia Fithri, Arga Buntara Jul 2024

Ammonia Exposure Based On The Length Of Work To Lung Function Abnormalities Among Traditional Scavengers, Maulyda Shakeela Jasmine, Fajaria Nurcandra, Nayla Kamilia Fithri, Arga Buntara

Kesmas

Lung function abnormalities can be caused by smoking habits or air pollution. Sanitary landfills can produce ammonia, which can cause lung function abnormalities. This study aimed to determine a relationship between ammonia exposure based on the length of work and lung function abnormalities among traditional scavengers at the Sumur Batu Landfill, Bekasi City, West Java Province, Indonesia. This analytical observational study applied quantitative methods and cross-sectional design. A total of 85 scavengers were selected using purposive sampling from March to May 2023. Data was obtained using a respondent characteristics questionnaire, spirometry, and spectrophotometer and analyzed using the Cox Regression Model. …


Ratification Status Of International Labour Organization (Ilo) Fundamental Conventions On Occupational Safety And Health, Ashish A. Trivedi, Alice Lai Jul 2024

Ratification Status Of International Labour Organization (Ilo) Fundamental Conventions On Occupational Safety And Health, Ashish A. Trivedi, Alice Lai

Occupational and Environmental Medicine Journal of Indonesia

Background: A safe and healthy work environment is key to sustainable development and in view of this, in June 2022, the International Labour Organization (ILO) declared this to be a fundamental principle and right at work, and recognised the Occupational Safety and Health Convention, 1981 (No. 155) and the Promotional Framework for Occupational Safety and Health Convention, 2006 (No. 187) as fundamental Conventions. The objective of this study was to assess the global as well as regional ratification status for ILO Conventions 155 and 187 among member countries, one year after their declaration as fundamental conventions.

Methods: Updated ratification status …


Examining The Relationship Between Shift Work And Diabetes Mellitus Among Nurses: An Evidence-Based Case Report, Angga Arifianto, Indah Suci Widyahening, Levina Chandra Khoe, M. Ikhsan Mokoagow Jul 2024

Examining The Relationship Between Shift Work And Diabetes Mellitus Among Nurses: An Evidence-Based Case Report, Angga Arifianto, Indah Suci Widyahening, Levina Chandra Khoe, M. Ikhsan Mokoagow

Occupational and Environmental Medicine Journal of Indonesia

Background : Work shifts could cause numerous health problems, such as sleep disorders, weight gain disorders, and unhealthy food intake consumption, leading to obesity and changes in blood glucose levels, that eventually lead to diabetes mellitus. This evidence-based case report aims to provide an evidence of association between shift work and the risk of diabetes mellitus among nurses.

Methods : We performed a literature searching from Pubmed, Embase, Cochrane, Scopus, and Google Scholar in September 2023 using keywords ‘shift work’ AND ‘diabetes’ AND ‘nurse’. We included studies that assessed the association between shift work and diabetes among nurses using observational …


Acceleration Return To Work Process After Accidents In The Manufacturing Industry – Literature Review, Lubna Sadat, Nurul Hidayah, Dede Iskandar Jul 2024

Acceleration Return To Work Process After Accidents In The Manufacturing Industry – Literature Review, Lubna Sadat, Nurul Hidayah, Dede Iskandar

Occupational and Environmental Medicine Journal of Indonesia

The manufacturing industry typically requires capacities on a large scale, increasing the risk of workplace accidents and illnesses. Thus, a stringent Occupational Health and Safety (OHS) guideline is needed, notably through early Return to Work (RTW) policies. In this review we explore how the acceleration of the RTW process influences employees, factories, and policy after accidents. Using a literature review approach, this research collected the data and information from from books, journals, and articles discussing the topic of OHS management in domestic and overseas factories.Acceleration of RTW included gradual task modifications, alternative tasks, and workstation adjustments to facilitate workers’ …


N-Acetyl-S-(N-Methylcarbamoyl)-Cysteine (Amcc) As Cumulative Biomonitoring Of Dimethylformamide Exposure Among Industrial Workers, Angga Arifianto, Muhammad Ilyas, Herqutanto . Jul 2024

N-Acetyl-S-(N-Methylcarbamoyl)-Cysteine (Amcc) As Cumulative Biomonitoring Of Dimethylformamide Exposure Among Industrial Workers, Angga Arifianto, Muhammad Ilyas, Herqutanto .

Occupational and Environmental Medicine Journal of Indonesia

Background: N,N-Dimethylformamide (DMF) is an aliphatic amide which is miscible with water and a majority of organic liquids. Due to its amphiphilic properties, it is a widely used industrial solvent, especially for polymers. DMF has been consistently hepatotoxic, inducing effects on the liver at lowest concentrations or doses. N-acetyl-S-(N-methylcarbamoyl)cysteine (AMCC) which is one major metabolites of DMF, found in urine after DMF exposure of the whole workweek.

Objective: To determine the way of AMCC can be use as biomarker of DMF exposure and the best possible sampling time.

Method: This study conducted a literature search using evidence-based databases …


The Importance Of Indonesian Workers’ Psychosocial Health In Demographic Bonus, Dewi S. Soemarko Jul 2024

The Importance Of Indonesian Workers’ Psychosocial Health In Demographic Bonus, Dewi S. Soemarko

Occupational and Environmental Medicine Journal of Indonesia

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Self-Management: A New Eight-Minute Stretching Program For Employees With Musculoskeletal Disorders (Msds), Siti Latipah, Shieva Nur Azizah Ahmad Jul 2024

Self-Management: A New Eight-Minute Stretching Program For Employees With Musculoskeletal Disorders (Msds), Siti Latipah, Shieva Nur Azizah Ahmad

Jurnal Keperawatan Indonesia

Musculoskeletal disorders (MSDs) are the main cause of workplace injuries. MSDs are health problems that attack the body’s propulsion systems, such as muscles, tendons, ligaments, joints, cartilage, and nerves. This study aims to determine the effectiveness of Self-Management: A New Eight-Minute Stretching Program against MSDs in a company X, Tangerang, Indonesia. A quantitative, quasi-experimental research method using a non-equivalent control group pre-test- post-test design was conducted on 90 respondents, who were divided into two sample groups by using side probability with a simple random sampling technique. The MSD risk measurement instrument used the Nordic Musculoskeletal Questionnaire. The results obtained showed …


Ambient Particulate Matter With Blood Pressure In Adult Women Living In Urban City, Nurusysyarifah Aliyyah, Haryoto Kusnoputranto, Bambang Wispriyono, Laila Fitria Jul 2024

Ambient Particulate Matter With Blood Pressure In Adult Women Living In Urban City, Nurusysyarifah Aliyyah, Haryoto Kusnoputranto, Bambang Wispriyono, Laila Fitria

Kesmas

Ambient air pollution, especially from fine particles, contributes to human mortality from cardiovascular and respiratory diseases, for which high blood pressure (BP) is a major modifiable risk factor. This study aimed to analyze the influence of ambient particulate matter (PM2.5) on the risk of high BP leading to hypertension. This study used a cross-sectional design on 118 adult women living in Central Jakarta, Indonesia. Participants were selected from a 1-km radius of the nearest air quality monitoring station with available data PM2.5. Linear regression was analyzed to examine the relationship between PM2.5 and systolic and diastolic BPs adjusted for potential …


New Approach To Mapping Regional Vulnerability In Controlling Tuberculosis Disease In Indonesia, Maria Holly Herawati, Asep Hermawan, Dasuki Dasuki, Hadi Supratikta, Al Asyary, M Rokhis Khomarudin, Muhammad Priyatna, Raflizar Raflizar, Kristina Kristina, Noer Endah Pracoyo, Dina Bisara, Cahya Tri Purnami, Mentari Nur Farida Suteja, Yusrial Bachtiar, Noor Edi Widya Sukoco, Doni Lasut Jul 2024

New Approach To Mapping Regional Vulnerability In Controlling Tuberculosis Disease In Indonesia, Maria Holly Herawati, Asep Hermawan, Dasuki Dasuki, Hadi Supratikta, Al Asyary, M Rokhis Khomarudin, Muhammad Priyatna, Raflizar Raflizar, Kristina Kristina, Noer Endah Pracoyo, Dina Bisara, Cahya Tri Purnami, Mentari Nur Farida Suteja, Yusrial Bachtiar, Noor Edi Widya Sukoco, Doni Lasut

Kesmas

Tuberculosis (TB) in Indonesia is still a health problem. The TB prevalence in Indonesia ranks second in the world after India in 2023. Regional factors, inadequate healthcare facilities, and limited resources (financial, human, and infrastructure) are challenges requiring innovation to help the government control TB. TB eradication efforts need to be made with a comprehensive and effective approach. One method used is to look at the vast territory of Indonesia, therefore, mapping the TB disease vulnerability is a highly recommended method. The use of a Geographic Information System is expected to help map the TB vulnerability areas in Indonesia. Given …


Adaptative Survival Of Aspergillus Fumigatus To Echinocandins Arises From Cell Wall Remodeling Beyond Β−1,3-Glucan Synthesis Inhibition, Malitha C. Dickwella Widanage, Isha Gautam, Daipayan Sarkar, Frederic Mentink-Vigier, Josh V. Vermaas, Shi You Ding, Andrew S. Lipton, Thierry Fontaine, Jean Paul Latgé, Ping Wang, Tuo Wang Jul 2024

Adaptative Survival Of Aspergillus Fumigatus To Echinocandins Arises From Cell Wall Remodeling Beyond Β−1,3-Glucan Synthesis Inhibition, Malitha C. Dickwella Widanage, Isha Gautam, Daipayan Sarkar, Frederic Mentink-Vigier, Josh V. Vermaas, Shi You Ding, Andrew S. Lipton, Thierry Fontaine, Jean Paul Latgé, Ping Wang, Tuo Wang

School of Graduate Studies Faculty Publications

Antifungal echinocandins inhibit the biosynthesis of β−1,3-glucan, a major and essential polysaccharide component of the fungal cell wall. However, the efficacy of echinocandins against the pathogen Aspergillus fumigatus is limited. Here, we use solid-state nuclear magnetic resonance (ssNMR) and other techniques to show that echinocandins induce dynamic changes in the assembly of mobile and rigid polymers within the A. fumigatus cell wall. The reduction of β−1,3-glucan induced by echinocandins is accompanied by a concurrent increase in levels of chitin, chitosan, and highly polymorphic α−1,3-glucans, whose physical association with chitin maintains cell wall integrity and modulates water permeability. The rearrangement of …


Treatment Of Large Intracranial Aneurysms Using The Woven Endobridge (Web): A Propensity Score-Matched Analysis, Basel Musmar, Hamza Salim, Nimer Adeeb, Assala Aslan, Bahaa Aljeradat, Jose Diestro, Rachel Mclellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann Lay, Adrien Guenego, Leonardo Renieri, Nicole Cancelliere, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Justin Vranic, Charlotte Chung, Mohamed Salem, Ivan Lylyk, Paul Foreman, Jay Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad Hafeez, Joshua Catapano, Muhammad Waqas, Vincent Tutino, Mohamed Ibrahim, Marwa Mohammed, M. Ozgur Ozates, Giyas Ayberk, James Rabinov, Yifan Ren, Clemens Schirmer, Mariangela Piano, Anna Kühn, Caterina Michelozzi, Stéphanie Elens, Robert Starke, Ameer Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie Nawka, Marios Psychogios, Christian Ulfert, Julian Spears, Brian Jankowitz, Jan-Karl Burkhardt, Ricardo Domingo, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Essibayi, Sunil Sheth, Gary Spiegel, Rabih Tawk, Boris Lubicz, Pietro Panni, Ajit Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan Brook, David Altschul, Andrew Ducruet, Felipe Albuquerque, Robert Regenhardt, Christopher Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A Aziz-Sultan, Stavropoula Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo Cuellar-Saenz, Pascal Jabbour, Vitor Pereira, Aman Patel, Adam Dmytriw Jul 2024

Treatment Of Large Intracranial Aneurysms Using The Woven Endobridge (Web): A Propensity Score-Matched Analysis, Basel Musmar, Hamza Salim, Nimer Adeeb, Assala Aslan, Bahaa Aljeradat, Jose Diestro, Rachel Mclellan, Oktay Algin, Sherief Ghozy, Mahmoud Dibas, Sovann Lay, Adrien Guenego, Leonardo Renieri, Nicole Cancelliere, Joseph Carnevale, Guillaume Saliou, Panagiotis Mastorakos, Kareem El Naamani, Eimad Shotar, Kevin Premat, Markus Möhlenbruch, Michael Kral, Justin Vranic, Charlotte Chung, Mohamed Salem, Ivan Lylyk, Paul Foreman, Jay Vachhani, Hamza Shaikh, Vedran Župančić, Muhammad Hafeez, Joshua Catapano, Muhammad Waqas, Vincent Tutino, Mohamed Ibrahim, Marwa Mohammed, M. Ozgur Ozates, Giyas Ayberk, James Rabinov, Yifan Ren, Clemens Schirmer, Mariangela Piano, Anna Kühn, Caterina Michelozzi, Stéphanie Elens, Robert Starke, Ameer Hassan, Mark Ogilvie, Anh Nguyen, Jesse Jones, Waleed Brinjikji, Marie Nawka, Marios Psychogios, Christian Ulfert, Julian Spears, Brian Jankowitz, Jan-Karl Burkhardt, Ricardo Domingo, Thien Huynh, Juan Carlos Martinez-Gutierrez, Muhammed Essibayi, Sunil Sheth, Gary Spiegel, Rabih Tawk, Boris Lubicz, Pietro Panni, Ajit Puri, Guglielmo Pero, Erez Nossek, Eytan Raz, Monika Killer-Oberfalzer, Christoph Griessenauer, Hamed Asadi, Adnan Siddiqui, Allan Brook, David Altschul, Andrew Ducruet, Felipe Albuquerque, Robert Regenhardt, Christopher Stapleton, Peter Kan, Vladimir Kalousek, Pedro Lylyk, Srikanth Boddu, Jared Knopman, Mohammad A Aziz-Sultan, Stavropoula Tjoumakaris, Frédéric Clarençon, Nicola Limbucci, Hugo Cuellar-Saenz, Pascal Jabbour, Vitor Pereira, Aman Patel, Adam Dmytriw

Department of Neurosurgery Faculty Papers

The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence …