Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Specialties (9507)
- Medical Sciences (6605)
- Life Sciences (4614)
- Public Health (4184)
- Oncology (2775)
-
- Diseases (2658)
- Biomedical Informatics (2631)
- Nursing (2504)
- Social and Behavioral Sciences (2485)
- Education (2333)
- Bioinformatics (2175)
- Medical Education (1742)
- Medical Genetics (1631)
- Mental and Social Health (1566)
- Rehabilitation and Therapy (1461)
- Genetic Phenomena (1273)
- Physical Sciences and Mathematics (1109)
- Pediatrics (1084)
- Dentistry (1046)
- Health and Physical Education (993)
- Occupational Therapy (882)
- Sports Sciences (822)
- Internal Medicine (793)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (766)
- Pharmacy and Pharmaceutical Sciences (730)
- Psychiatry and Psychology (730)
- Neurology (707)
- Health and Medical Administration (673)
- Surgery (664)
- Institution
-
- The Texas Medical Center Library (5918)
- Washington University School of Medicine (1699)
- Thomas Jefferson University (955)
- University of Texas Rio Grande Valley (766)
- University of Kentucky (660)
-
- HCA Healthcare (600)
- Chulalongkorn University (511)
- LSU Health New Orleans (498)
- Edith Cowan University (493)
- Western Kentucky University (453)
- American Dental Association (405)
- Universitas Indonesia (376)
- Wayne State University (372)
- University of Nebraska Medical Center (370)
- Rowan University (353)
- Aga Khan University (335)
- Children's Mercy Kansas City (300)
- University of South Carolina (296)
- University of Nebraska - Lincoln (291)
- Walden University (266)
- University of St Augustine for Health Sciences (264)
- Boise State University (256)
- Children's Health Medical Center Dallas (253)
- Nova Southeastern University (252)
- University of the Pacific (214)
- Old Dominion University (212)
- Corewell Health (200)
- Providence (191)
- Liberty University (182)
- Chapman University (180)
- Keyword
-
- Humans (5389)
- Female (2668)
- Male (2353)
- Animals (1551)
- Adult (1420)
-
- ICTS (Institute of Clinical and Translational Sciences) (1420)
- Middle Aged (1357)
- Aged (1146)
- Mice (1048)
- Child (682)
- Adolescent (573)
- COVID-19 (484)
- Retrospective Studies (477)
- United States (473)
- Young Adult (429)
- Neoplasms (391)
- Treatment Outcome (390)
- Risk Factors (330)
- Biomarkers (327)
- Mutation (322)
- Tumor (321)
- Infant (317)
- Aged, 80 and over (313)
- Mental health (308)
- Pregnancy (280)
- Mice, Inbred C57BL (275)
- Child, Preschool (270)
- Occupational therapy (270)
- Cell Line, Tumor (261)
- Brain (256)
- Publication
-
- Faculty, Staff and Student Publications (3547)
- Faculty, Staff and Students Publications (1936)
- 2020-Current year OA Pubs (1689)
- Research outputs 2022 to 2026 (472)
- International Journal of Exercise Science: Conference Proceedings (415)
-
- Chulalongkorn University Theses and Dissertations (Chula ETD) (309)
- School of Medicine Faculty Publications (295)
- Research Symposium (275)
- Patient Education Projects (255)
- Walden Dissertations and Doctoral Studies (246)
- International Journal of Physical Activity and Health (232)
- Rowan-Virtua Research Day (213)
- School of Medicine Publications (209)
- Aluminum in Beverages and Foods: A Compilation (186)
- Research Colloquium (178)
- Posters (167)
- Annual Research Symposium (165)
- Doctor of Nursing Practice Projects (163)
- Theses and Dissertations (159)
- Doctoral Dissertations and Projects (147)
- Electronic Theses and Dissertations (147)
- Virginia Dental Journal (139)
- Faculty Scholarship (130)
- Manuscripts, Articles, Book Chapters and Other Papers (129)
- South Atlantic Division GME Research Day 2024 (125)
- Markey Cancer Center Faculty Publications (120)
- Center for Medical Ethics and Health Policy Staff Publications (117)
- Research Day (116)
- The Journal of the Michigan Dental Association (112)
- Turkish Journal of Medical Sciences (112)
- Publication Type
Articles 27241 - 27242 of 27242
Full-Text Articles in Medicine and Health Sciences
A Novel Crispr/Cas9-Mediated Mouse Model Of Colon Carcinogenesis, Hajime Kashima, Anthony Fischer, Daniel A Veronese-Paniagua, Vered A Gazit, Changqing Ma, Yan Yan, Marc S Levin, Blair B Madison, Deborah C Rubin
A Novel Crispr/Cas9-Mediated Mouse Model Of Colon Carcinogenesis, Hajime Kashima, Anthony Fischer, Daniel A Veronese-Paniagua, Vered A Gazit, Changqing Ma, Yan Yan, Marc S Levin, Blair B Madison, Deborah C Rubin
2020-Current year OA Pubs
BACKGROUND & AIMS: Human sporadic colorectal cancer (CRC) results from a multistep pathway with sequential acquisition of specific genetic mutations in the colorectal epithelium. Modeling CRC in vivo is critical for understanding the tumor microenvironment. To accurately recapitulate human CRC pathogenesis, mouse models must include these multi-step genetic abnormalities. The aim of this study was to generate a sporadic CRC model that more closely mimics this multi-step process and to use this model to study the role of a novel Let7 target PLAGL2 in CRC pathogenesis.
METHODS: We generated a CRISPR/Cas9 somatic mutagenesis mouse model that is inducible and multiplexed …
Evolution Of Proton Radiation Therapy Brainstem Constraints On The Pediatric Proton/Photon Consortium Registry, Dora Correia, Stephanie M Perkins, Et Al.
Evolution Of Proton Radiation Therapy Brainstem Constraints On The Pediatric Proton/Photon Consortium Registry, Dora Correia, Stephanie M Perkins, Et Al.
2020-Current year OA Pubs
PURPOSE: Increasing concern that brainstem toxicity incidence after proton radiation therapy might be higher than with photons led to a 2014 University of Florida (UF) landmark paper identifying its risk factors and proposing more conservative dose constraints. We evaluated how practice patterns changed among the Pediatric Proton/Photon Consortium Registry (PPCR).
MATERIAL AND METHODS: This prospective multicenter cohort study gathered data from patients under the age of 22 years enrolled on the PPCR, treated between 2002 and 2019 for primary posterior fossa brain tumors. After standardizing brainstem contours, we garnered dosimetry data and correlated those meeting the 2014 proton-specific brainstem constraint …