Medicine and Health Sciences Commons^™

General Psychology 2e, Will Stutterheim

All Open Educational Resources

General Psychology 2e offers an insightful exploration into the complexities of the field of psychology and all that it has to offer. This book provides a thorough introduction to the foundational principles of psychology, covering essential theories, research findings, and applications that illustrate the intricate workings of the mind.

The text begins with a historical overview of psychology, tracing its evolution from philosophical roots to its establishment as a scientific discipline. It then delves into essential topics regarding stress and mental health disorders and concludes with therapy and treatment approaches. It then covers research in psychology, biopsychology, consciousness, and perception. …

Unlocking Icu Barriers: Investigating The Challenges Of Early Progressive Mobility, Leslie S. Bigler

Doctoral Projects

Approximately 800,000 patients in the United States annually are admitted to the Intensive Care Unit (ICU) due to critical illnesses and prolonged immobility contributes to poor patient outcomes. While existing data demonstrates early and progressive mobility helps improve outcomes, adherence remains inconsistent for a variety of reasons such as safety concerns, staffing, and lack of knowledge and confidence of mobilization techniques. This quality improvement project, conducted in a 20-bed Medical Intensive Care Unit, asked staff to identify barriers to adherence to mobility protocols. Nurse managers and clinical educators play a crucial role in addressing these issues using strategies such as …

Association Between Time From Surgery To Radiation Therapy And Multimodality Treatment Outcomes In Hpv+ Head And Neck Cancer: A Multi-Institutional Cohort Experience, Muneeb Niazi, Ryan Miller, Ryann Kolb, Wenyan Ji, Alicia Lozano, Monica Ahrens, Alexandra Hanlon, Max Pickles, Andrew Song, Voichita Bar-Ad, Neil Hockstein, Sujung Park, Adam Raben, Gaurav Shukla

Department of Radiation Oncology Faculty Papers

Purpose: Oropharyngeal squamous cell cancers (OPSCCs) are traditionally managed with surgery and, if indicated, adjuvant radiation therapy (RT) with or without chemotherapy. NCCN recommends keeping the time from surgery to the start of RT (TSRT) within 6 weeks to avoid possibly compromising patient outcomes. HPV+ OPSCCs behave more favorably than HPV- OPSCCs. We hypothesized that TSRT beyond 6 weeks may not portend poorer outcomes for the former. Methods: We identified nonmetastatic, high-risk HPV+ OPSCCs treated with multimodal therapy at 2 institutions. Prolonged TSRT was defined as >6 weeks and was evaluated for association with recurrence-free survival (RFS). Radiation treatment time …

A Recreational Therapy-Based Bibliotherapy Program For Perceived Stress And Coping Among Siblings Of Individuals With Intellectual And Developmental Disabilities, Lindsey Kirschbaum

All Dissertations

Siblings of individuals with intellectual and developmental disabilities (IDD) face unique challenges and experiences different from their peers who do not have a sibling with IDD. These challenges can include increased sense of responsibility at home, decreased attention from parents, and feelings of social isolation; all of which can increase stress. While sibling support groups offer opportunities for siblings of individuals with IDD to connect with other siblings, these groups do not formally focus on improving participants’ stress-coping outcomes. Bibliotherapy has been shown to help youth express stress-related feelings and learn stress-coping strategies. However, no known research has assessed the …

Ultrashort Pulsed Laser Treatment Is Effective At Sterilizing Metal Surfaces For Planetary Protection, Kaleb Mcquillan

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

To prevent forward contamination from microbes aboard spacecraft intended for exploration of solar system bodies there is a need for effective sterilization methods. However, current techniques are both time-consuming and expensive. For example, dry heat sterilization requires removal from the assembly site and several days of treatment. Furthermore, some components such as optics and electronics are not compatible with current sterilization techniques. In this thesis, a novel femtosecond laser surface processing technique for the rapid sterilization of spacecraft hardware is reported. Femtosecond lasers produce extremely high photon fluxes (10²⁹ photons/s*cm², ~0.03 J/cm²) in extremely short …

Himmelfarb Library Liaison Letter - August 2024, The George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Library Liaison Letters

No abstract provided.

Investigating The Role Of Insulin-Like Signaling In Paclitaxel-Induced Nociceptive Hypersensitivity Using Drosophila Melanogaster, Sreepradha Sridharan

Dissertations and Theses (Open Access)

Paclitaxel (PTX), a chemotherapeutic that alters microtubule dynamics, is known to induce nociceptive hypersensitivity and sensory neuron damage in human patients and in Drosophila larvae. We used a modified feeding protocol to establish a genetically tractable Drosophila model of PTX-induced hypersensitivity. Larvae fed PTX exhibited hypersensitivity to thermal and mechanical stimuli. Thermal hypersensitivity was observed at low concentrations of PTX (even below 1 μM per ml of food), begins within 8 hours of PTX feeding, and did not completely resolve at the larval stage. Live imaging of peripheral thermal nociceptors showed that this hypersensitivity precedes observable neuronal damage. At low …

Determining Spatiotemporal Regulation Of Actin Dynamics In Choroid Fissure Closure, Cristal Gonzalez

Master's Theses

There are several stages of development necessary for proper vision. During vertebrate eye development, early eye morphology progresses in three stages: optic cup morphogenesis, basement membrane breakdown, and tissue fusion. Eye development is an intricate collaboration between many cells and requires tissues to migrate and bridge together. The following research investigates the Danio Rerio eye development to understand the molecular regulation of choroid fissure closure (CFC). It is hypothesized that CFC requires temporal and spatial regulation of actin dynamics. We investigate this question using chemical inhibitors, cytochalasin D, an actin treadmilling inhibitor, and NSC23766, a Rac-GEF inhibitor of the actin …

Functional Contribution Of Epithelial To Mesenchymal Transition Program On Krasg12d Targeting Efficacy In Pancreatic Cancer, Ana S. Maldonado

Dissertations and Theses (Open Access)

Functional contribution of epithelial to mesenchymal transition program on KRAS^G12D targeting efficacy in pancreatic cancer

Ana S. Maldonado, BS

Advisory Professor: Raghu Kalluri, M.D., Ph.D.

Pancreatic Ductal Adenocarcinoma (PDAC), a highly aggressive, metastatic, and therapeutically resistant form of pancreatic cancer has been projected to become the second-leading cause of cancer related mortality in the United States. This is driven by its detection difficulty, treatment efficacy, and asymptomatic nature, among other factors. PDAC is driven predominantly by KRAS^G12D mutations, which are responsible for the initial development of pancreatic intraepithelial neoplasia (Pan-IN) lesions, that are further maintained and progressed until …

Ot's Role In Community Accessibility At Public Parks And Playgrounds For Parents With Disabilities, Janae Paulo, Amy Lyons-Brown, Stacy Frauwith, Lena Gipson Showalter

Summer 2024 OTD Capstone Symposium

Public parks and playgrounds play a crucial role in fostering parent-child interaction, social inclusion, and community engagement. However, these essential recreational spaces often remain inaccessible to individuals with disabilities (Lynch et al., 2020). Research underscores the benefits of inclusive playgrounds, yet many are not designed to accommodate adults with disabilities, thus creating barriers for parents with disabilities who wish to engage with their children (Dalpra, 2022; Jacob et al., 2017). Although occupational therapy (OT) practitioners are instrumental in ensuring environmental accessibility within home settings, their involvement in the design of public spaces is limited. Young et al. (2019) advocate for …

Impacts Of Pelvic Floor Dysfunction On The Occupations Of Postpartum Women, Julia Hernandez, Amy Lyons-Brown

Summer 2024 OTD Capstone Symposium

This study investigates the impact of pelvic floor dysfunction (PFD) on the daily activities of postpartum women. Eleven women participated in an online survey, with four engaging in follow-up interviews via Microsoft Teams. The survey indicated that 91% of respondents experienced at least one symptom of PFD, including urine leakage, difficulty reaching the toilet in time, unexpected passing of wind, decreased vaginal sensation, a bulge at the vaginal opening, pelvic heaviness, and vulvar pain during sex. Despite these prevalent symptoms, 82% had not been offered pelvic floor therapy.

Participants rated their awareness of pelvic floor health topics predominantly as "Less …

Technical Considerations In Robotic Aberrant Right Subclavian Artery Resection For Dysphagia Lusoria, Luke Meredith, Emily Isch, Mohammed Ali, Michael Nooromid, Olugbenga Okusanya

Department of Surgery Faculty Papers

Dysphagia lusoria occurs due to compression of the esophagus as an aberrant right subclavian artery (ARSA) crosses the mediastinum. Surgical management includes open, hybrid, and endovascular techniques, with no consensus gold standard. There are few reports of robotic-assisted ARSA resection. We describe the innovative technique and outcomes for two patients who successfully underwent robotic-assisted transthoracic resection of an ARSA after right carotid–subclavian bypass for dysphagia lusoria. Both patients experienced improvement or resolution of their dysphagia and no major complications. In select patients with a noncalcified origin of the ARSA without aneurysmal degeneration, the robotic-assisted approach represents a viable option.

Quality Improvement Project: Fall Prevention Among Older Adults In Snf Through Staff Education And Hourly Rounding, Reshmi Abraham

Doctor of Nursing Practice Projects

Falls among elderly individuals in Skilled Nursing Facilities (SNF) pose a widespread and significant healthcare challenge, often resulting in severe injuries, reduced quality of life, and increased healthcare expenses. Despite the current efforts to prevent falls, they still occur frequently, underscoring the importance of effective interventions for prevention. This Doctor of Nursing Practice (DNP) project focuses on quality improvement (QI) in healthcare. It aims to reduce fall rates among older adults in SNF by providing staff education and implementing scheduled hourly rounding. This approach aligns with existing research, emphasizing the importance of proactive patient monitoring and improved staff knowledge in …

Using Short-Form Videos To Get Clinical Trial Newcomers To Sign Up: Message-Testing Experiment, Sisi Hu, Ciera E. Kirkpatrick, Namyeon Lee, Yoorim Hong, Sungkyoung Lee, Amanda Hinnant

Journalism Faculty Publications and Presentations

Background: Recruiting participants for clinical trials poses challenges. Major barriers to participation include psychological factors (eg, fear and mistrust) and logistical constraints (eg, transportation, cost, and scheduling). The strategic design of clinical trial messaging can help overcome these barriers. While strategic communication can be done through various channels (eg, recruitment advertisements), health care providers on the internet have been found to be key sources for communicating clinical trial information to US adults in the social media era.

Objective: This study aims to examine how communication source (ie, medical doctors and peers) and message framing of TikTok videos (ie, psychological and …

Preschool Executive Control And Adolescent Dietary Outcomes: Highlighting The Role Of Context, Marla Lopez

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Research has identified executive control (EC) as an important predictor of dietary outcomes among youth. Executive control in preschool age has been shown to predict important outcomes across development for youth, indicating that good, foundational EC abilities are associated with successful development in later life. Dietary outcomes across adolescence, an important transitional period for establishing healthy eating behaviors, are understudied. Therefore, the current study sought to link two critical developmental periods, examining how preschool EC is associated with dietary trajectories across adolescence. Further, the study aimed to identify how contextual factors, specifically indices of socio-economic status and the home and …

Cerebrovascular Reactivity Mri As A Biomarker For Cerebral Small Vessel Disease–Related Cognitive Decline: Multi-Site Validation In The Markvcid Consortium, Peiying Liu, Zixuan Lin, Kaisha Hazel, George Pottanat, Cuimei Xu, Dengrong Jiang, Jay J. Pillai, Emma Lucke, Christopher E. Bauer, Brian T. Gold, Steven M. Greenburg, Karl G. Helmer, Kay Jann, Gregory Jicha, Joel Kramer, Pauline Maillard, Rachel M. Mulavelil, Pavel Rodriguez, Claudia L. Satizabal, Kristin Schwab, Sudha Seshadri, Herpreet Singh, Ángel G. Velarde Dediós, Danny J. J. Wang, Rita R. Kalyani, Abhay Moghekar, Paul B. Rosenberg, Sevil Yasar, Marilyn Albert, Hanzhang Lu

Neurology Faculty Publications

INTRODUCTION: Vascular contributions to cognitive impairment and dementia (VCID) represent a major factor in cognitive decline in older adults. The present study examined the relationship between cerebrovascular reactivity (CVR) measured by magnetic resonance imaging (MRI) and cognitive function in a multi-site study, using a predefined hypothesis.

METHODS: We conducted the study in a total of three analysis sites and 263 subjects. Each site performed an identical CVR MRI procedure using 5% carbon dioxide inhalation. A global cognitive measure of Montreal Cognitive Assessment (MoCA) and an executive function measure of item response theory (IRT) score were used as outcomes.

RESULTS: CVR …

Effect Of Male Partners' Involvement And Support On Reproductive, Maternal And Child Health And Well-Being In East Africa: A Scoping Review, Richard Fletcher, Faye Forbes, Abel Fekadu Dadi, Getachew Mullu Kassa, Casey Regan, Anna Galle, Addisu Beyene, Rebecca Liackman, Marleen Temmerman

Centre of Excellence in Women and Child Health

Background and Aims: East African countries have high rates of maternal and childmortality and morbidity. Studies have shown that the involvement of male partners inreproductive health can benefit maternal and child health (MCH). This scoping reviewaims to provide an overview of the evidence across East Africa that describes malepartner involvement and its effect on maternal, reproductive, and child well‐being.

Methods: Ten databases were searched to identify quantitative data on male'sinvolvement in East Africa. Studies reporting qualitative data, “intention to use” dataor only reporting on male partner's education or economic status were excluded.Studies were organized into five a priori categories: antenatal …

Psychological Pitfalls Of The Modern Percussionist: A Survey Of Coping Mechanisms For Downward Spirals In Mental Health, Andrew Naughton

UNLV Theses, Dissertations, Professional Papers, and Capstones

This document explores three key facets of mental health significantly impacting percussionists in both educational and professional settings: Imposter Syndrome, sleep deprivation, and stress management. The primary focus is to understand the impact of these psychological conditions on percussionists and discover effective approaches to prevent, alleviate, or manage these ailments. This document is divided into four sections. The initial section delineates the concept of “Imposter Syndrome” and discusses its various manifestations as encountered by percussionists in both educational and professional environments. The second section discusses the consequences of sleep deprivation on mental well-being when it is disregarded. The third section …

Vitamin-D Deficiency & Depression: Is There An Association? Average Data From Gulf Cooperation Council Countries, Shamil Wanigaratne, Amar Ahamd, Fatme Al Anouti, Mitha Al Balushi, Syed Javaid

All Works

Aims The evidence for the association between vitamin-D deficiency and depression, although equivocal, has been established in several populations in different countries and supported by meta-analytical studies 1 . Much of the evidence for this comes from Western countries 2 . Similarly, the evidence for the benefits of supplementation, although shown, also comes from similar populations and is equivocal 3 . Need for data from different populations and for randomized controlled trials to establish causality is stressed by most researchers. This study aims for presentation reviews of the association between vitamin-D and depression in the GCC, using the publicly available …

Differences In Bilinguals And Multilinguals Diagnosed With Alzheimer's Disease, Nathalie Rios Carreon

University Honors Theses

Alzheimer’s Disease does not have a cure but there are different things that can be done to manage the disease. Keeping your brain healthy is important to keep cognitive reserve (CR) strong and intact. One way to keep CR intact is to speak more than one language. Previous research done shows that monolinguals typically get diagnosed with Alzheimer's disease 4 to 5 years earlier than bilinguals and multilinguals. Using existing articles it was found that this new research was similar to research already done. Speaking more than one language keeps the brain healthy in many different ways. Research suggests that …

Cord Blood Troponin I Levels: Biomarker Evidence Of Fetal Cardiac Injury In Intrahepatic Cholestasis Of Pregnancy, Itamar Futterman, Hitangee Jain, Rodney Mclaren, Jonathan Mays

Department of Obstetrics and Gynecology Faculty Papers

BACKGROUND: Intrahepatic cholestasis of pregnancy has been linked to sudden stillbirth. The suddenness of the stillbirths in these cases have led clinicians to suspect that the pathogenesis of stillbirth in women with intrahepatic cholestasis of pregnancy is not related to asphyxia but rather to an undefined etiology. One leading hypothesis relates certain bile acid metabolites to myocardial injury. OBJECTIVE: The purpose of this study was to determine whether cord blood troponin I levels are increased in fetuses born to mothers with a diagnosis of intrahepatic cholestasis of pregnancy. STUDY DESIGN: A prospective, case-control study was performed at a single institution …

Effortless Mindfulness Toolkit: Easy Meditation Scripts To Begin Each Class., Brett Whysel

Open Educational Resources

The Effortless Mindfulness in the Classroom Toolkit is an open educational resource designed to create happier classrooms, boost student engagement, and foster a sense of community through brief, effective mindfulness exercises. This comprehensive toolkit provides educators with everything they need to seamlessly integrate mindfulness practices into their teaching routines, regardless of prior experience. The toolkit includes introductory slides, 15 ready-to-use meditation scripts, and accompanying audio recordings, covering a variety of mindfulness techniques such as focused breathing, body scans, and loving-kindness meditations. Each meditation is paired with a reflective prompt to deepen student engagement and reinforce the benefits of mindfulness. Additionally, …

Emergency Sheltering And Autism, Rrose Lamay

Capstone Experience: Master of Public Health

While research is abundant on the individual topics of caring for vulnerable populations in a disaster, Autism Spectrum Disorder. There is little guidance available that ties these together and deals directly with the emergency sheltering of minors on the autism spectrum. The information gap extends to preparedness for caregivers of children on the spectrum, shelter workers, and community members. This vulnerable population is known to have specific needs during disasters when mass sheltering is needed. These needs could be addressed by the development of a comprehensive literature review, a survey, and a coinciding guide. The literature review discusses preexisting academic …

Addendum: A Small Molecule Produced By Lactobacillus Species Blocks Candida Albicans Filamentation By Inhibiting A Dyrk1-Family Kinase, Jessie Macalpine, Martin Daniel-Ivad, Zhongle Liu, Junko Yano, Nicole M. Revie, Robert T. Todd, Peter J. Stogios, Hiram Sanchez, Teresa R. O'Meara, Thomas A. Tompkins, Alexei Savchenko, Anna Selmecki, Amanda O. Veri, David R. Andes, Paul L. Fidel, Nicole Robbins, Justin Nodwell, Luke Whitesell, Leah E. Cowen

School of Dentistry Faculty Publications

No abstract provided.

Automatic Uncovering Of Patient Primary Concerns In Portal Messages Using A Fusion Framework Of Pretrained Language Models, Yang Ren, Yuqi Wu, Jungwei W. Fan, Aditya Khurana, Sunyang Fu, Dezhi Wu, Hongfang Liu, Ming Huang

Publications

Objectives: The surge in patient portal messages (PPMs) with increasing needs and workloads for efficient PPM triage in healthcare settings has spurred the exploration of AI-driven solutions to streamline the healthcare workflow processes, ensuring timely responses to patients to satisfy their healthcare needs. However, there has been less focus on isolating and understanding patient primary concerns in PPMs-a practice which holds the potential to yield more nuanced insights and enhances the quality of healthcare delivery and patient-centered care. Materials and Methods: We propose a fusion framework to leverage pretrained language models (LMs) with different language advantages via a Convolution Neural …

Barriers And Facilitators To 24-Month Maintenance Of The Faith, Activity, And Nutrition Program In The U.S., Kelsey R. Day, John A. Bernhart Ph.D., Rd, Sara Wilcox Phd

Faculty Publications

Little is known about the barriers and facilitators to organizational maintenance of faith-based health promotion programs. This study used qualitative data (collected from 2016–2019) from pastors (n = 81) and program coordinators (n = 103) to identify barriers and facilitators to 24-month maintenance of a faith-based physical activity (PA) and healthy eating (HE) intervention in South Carolina. Barriers differed for PA versus HE: resistance to change impeded HE while church characteristics tended to impede PA. Similar themes emerged for PA and HE facilitators: healthy opportunities, church communication, and consistency. Future research should build upon this study to tailor faith-based health …

The Scoop, Vol. 11 Issue 5, August 2024, Health Sciences Library

Volume 11

Latest news and updates from the Health Sciences Library in our monthly newsletter for August 2024.

Comparative Analysis Of Transfer Learning Strategies For Polyp Detection In Colonoscopy Images Using Yolov8, Fabian Vazquez Jr.

Theses and Dissertations

The early detection of polyps during colonoscopy procedures is crucial for preventing colorectal cancer, a leading cause of cancer-related deaths globally. Traditional methods for polyp detection are often time-consuming and prone to human error. This thesis investigates the effectiveness of transfer learning, the process of taking a pre-trained model that was trained on a large dataset and adapting it to a new, but related task, requiring less data and time for training. This research compares whether the YOLOv8 model trained from scratch on a specific polyp dataset is outperformed by transfer learning methods such as utilizing a pretrained model on …

Moral Disengagement And The Tendency To Engage In Academic Dishonesty In Prelicensure Nursing Students, Sarah Guimaraes

Electronic Theses and Dissertations

Despite decades of research, academic dishonesty remains a significant concern in nursing education. The connection of academic dishonesty to dishonest clinical practice presents a moral imperative for nurse researchers to find new facets of understanding these phenomena. Literature regarding moral disengagement in health care is minimal and is even less prevalent in the context of nursing education. The purpose of this study was to determine the effects of moral disengagement on prelicensure nursing students’ tendencies to engage in academic dishonesty in their last or next to last semester of a nursing program. A correlational design via survey method was used. …

Soreness And Perceptual Responses From The Combined Use Of Accentuated Eccentric Loading And Cluster Sets During A Strength-Endurance Training Block, Ryan Lis

Electronic Theses and Dissertations

The first purpose of the current study was to analyze palpation and movement soreness via the visual analog scale (PVAS and MVAS, respectively) between accentuated eccentric loading (AEL) and traditional resistance training (TRAD) during a month of strength-endurance training. This was measured at the lower body (LB: gluteus maximus and vastus lateralis) and the upper body (UB: pectoralis major, anterior deltoid, and triceps brachii) every day of training (1-20 days) immediately before warming up and after finishing the training session. The MVAS was conducted at a self-selected fast speed. The second purpose was to measure perceptual responses between AEL and …