Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Specialties (9450)
- Medical Sciences (6554)
- Life Sciences (4609)
- Public Health (4171)
- Oncology (2771)
-
- Diseases (2656)
- Biomedical Informatics (2632)
- Nursing (2501)
- Social and Behavioral Sciences (2476)
- Education (2328)
- Bioinformatics (2176)
- Medical Education (1741)
- Medical Genetics (1631)
- Mental and Social Health (1566)
- Rehabilitation and Therapy (1461)
- Genetic Phenomena (1273)
- Physical Sciences and Mathematics (1102)
- Pediatrics (1083)
- Dentistry (1045)
- Health and Physical Education (991)
- Occupational Therapy (882)
- Sports Sciences (822)
- Internal Medicine (793)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (766)
- Pharmacy and Pharmaceutical Sciences (726)
- Psychiatry and Psychology (725)
- Neurology (706)
- Health and Medical Administration (672)
- Surgery (617)
- Institution
-
- The Texas Medical Center Library (5872)
- Washington University School of Medicine (1688)
- Thomas Jefferson University (955)
- University of Texas Rio Grande Valley (763)
- University of Kentucky (660)
-
- HCA Healthcare (600)
- Chulalongkorn University (511)
- Edith Cowan University (493)
- LSU Health New Orleans (476)
- Western Kentucky University (453)
- American Dental Association (405)
- Universitas Indonesia (376)
- Wayne State University (372)
- University of Nebraska Medical Center (370)
- Rowan University (353)
- Aga Khan University (335)
- Children's Mercy Kansas City (300)
- University of South Carolina (296)
- University of Nebraska - Lincoln (291)
- Walden University (266)
- University of St Augustine for Health Sciences (264)
- Boise State University (256)
- Children's Health Medical Center Dallas (253)
- Nova Southeastern University (252)
- University of the Pacific (213)
- Old Dominion University (212)
- Corewell Health (200)
- Providence (191)
- Liberty University (182)
- Chapman University (180)
- Keyword
-
- Humans (5370)
- Female (2662)
- Male (2346)
- Animals (1540)
- Adult (1416)
-
- ICTS (Institute of Clinical and Translational Sciences) (1410)
- Middle Aged (1353)
- Aged (1145)
- Mice (1042)
- Child (680)
- Adolescent (571)
- COVID-19 (481)
- Retrospective Studies (475)
- United States (472)
- Young Adult (427)
- Neoplasms (389)
- Treatment Outcome (389)
- Risk Factors (330)
- Biomarkers (326)
- Mutation (320)
- Tumor (320)
- Infant (316)
- Aged, 80 and over (312)
- Mental health (308)
- Pregnancy (276)
- Mice, Inbred C57BL (272)
- Occupational therapy (270)
- Child, Preschool (269)
- Cell Line, Tumor (260)
- Brain (255)
- Publication
-
- Faculty, Staff and Student Publications (3548)
- Faculty, Staff and Students Publications (1889)
- 2020-Current year OA Pubs (1678)
- Research outputs 2022 to 2026 (472)
- International Journal of Exercise Science: Conference Proceedings (415)
-
- Chulalongkorn University Theses and Dissertations (Chula ETD) (309)
- School of Medicine Faculty Publications (295)
- Research Symposium (275)
- Patient Education Projects (255)
- Walden Dissertations and Doctoral Studies (246)
- International Journal of Physical Activity and Health (232)
- Rowan-Virtua Research Day (213)
- School of Medicine Publications (207)
- Aluminum in Beverages and Foods: A Compilation (186)
- Research Colloquium (178)
- Posters (167)
- Annual Research Symposium (165)
- Doctor of Nursing Practice Projects (163)
- Theses and Dissertations (159)
- Doctoral Dissertations and Projects (147)
- Electronic Theses and Dissertations (146)
- Virginia Dental Journal (139)
- Faculty Scholarship (130)
- Manuscripts, Articles, Book Chapters and Other Papers (129)
- South Atlantic Division GME Research Day 2024 (125)
- Markey Cancer Center Faculty Publications (120)
- Center for Medical Ethics and Health Policy Staff Publications (117)
- Research Day (116)
- The Journal of the Michigan Dental Association (112)
- Turkish Journal of Medical Sciences (112)
- Publication Type
Articles 2701 - 2730 of 27182
Full-Text Articles in Medicine and Health Sciences
Laboratory Literacy: Surveying Lab Result Interpretations Of A Local Patient Population, Jordan Franco, Mark K. Fung
Laboratory Literacy: Surveying Lab Result Interpretations Of A Local Patient Population, Jordan Franco, Mark K. Fung
Patient Experience Journal
A patient's independent interpretation of their medical laboratory data has become an unspoken prerequisite in the current age of medicine. In the outpatient setting, it is anecdotally commonplace for patients to receive their lab results before their physicians, resulting in patients often relying on self-interpretations of their results. This study analyzed the degree to which patients are comfortable interpreting lab results and sought to shed light on the question: How are patients interpreting their laboratory reports? A survey was constructed to include the items from a validated health literacy screening tool, followed by items inquiring about the respondent's experience and …
A Quality Improvement Initiative Using Discharge Education Videos To Improve Communication With Families In A Pediatric Urgent Care, Hannah G. Carron, Gisella Valderrama, Adam A. Vukovic
A Quality Improvement Initiative Using Discharge Education Videos To Improve Communication With Families In A Pediatric Urgent Care, Hannah G. Carron, Gisella Valderrama, Adam A. Vukovic
Patient Experience Journal
Introduction: Effective discharge communication, often given in verbal and written form, during pediatric acute healthcare visits positively impacts caregiver satisfaction and competency in providing at-home care. Institutions are beginning to incorporate evidence-based, and standardized multimedia education to try to further improve these outcomes.
Methods: For this QI initiative, educational videos were created and shown to families prior to discharge from a pediatric urgent care. PDSA cycles focused on development of an electronic medical record (EMR) order to provide video education, a best practice alert regarding this order, and recurrent staff education. The primary outcome measure was the percentage …
Experiences Of Psychosocial Support In Group Rehabilitation Interventions From Adults With Chronic Conditions – A Qualitative Systematic Review, Jenny Mäkeläinen, Ulla Jämsä, Anne Oikarinen, Maria Kääriäinen, Heidi Siira
Experiences Of Psychosocial Support In Group Rehabilitation Interventions From Adults With Chronic Conditions – A Qualitative Systematic Review, Jenny Mäkeläinen, Ulla Jämsä, Anne Oikarinen, Maria Kääriäinen, Heidi Siira
Patient Experience Journal
Aims and objectives: Psychosocial support is essential in group rehabilitation interventions aiming at supporting adaptation to chronic illness and disability. Aim was to synthesize qualitative evidence on how adults with chronic conditions experience psychosocial support in group rehabilitation interventions. Materials and Methods: Four databases (CINAHL, Medic, Pubmed, Scopus) were searched for qualitative studies published between 2009-2022. Study selection and critical appraisal were independently performed by two authors using the JBI Critical Appraisal Checklist. Study selection and critical appraisal were independently performed by two authors. Data were synthesized through inductive content analysis. Results: The findings from nine studies were synthesized into …
Post-Pandemic Needs Of Unpaid Family And Friend Caregivers To Effectively Continue Caregiving Duties In One Northern Ontario Health Authority, Jodi Webber, Erin Mulroney, Mark Tatasciore, Brianna Smith, Patti-Jo Duggan, Louis Ferron, Hannah Albani, Bianca Feitelberg, Laura Tenhagen, Sophia Myles
Post-Pandemic Needs Of Unpaid Family And Friend Caregivers To Effectively Continue Caregiving Duties In One Northern Ontario Health Authority, Jodi Webber, Erin Mulroney, Mark Tatasciore, Brianna Smith, Patti-Jo Duggan, Louis Ferron, Hannah Albani, Bianca Feitelberg, Laura Tenhagen, Sophia Myles
Patient Experience Journal
The Covid-19 pandemic had a significant impact on the support networks for older adults and caregivers as health and social care systems were forced to dramatically change the ways patients and clients interacted with providers, services, and programs. In Northern Ontario, caregivers are older, caring in more intense situations, more likely to be caring for multiple care recipients simultaneously and less likely to be in contact with health professionals. This research sought to explore the post-pandemic needs of caregivers in a Northern Ontario health catchment to better understand the needed supports. Using a collaborative and co-design approach with caregiver advisors …
Patients' Perceptions: A Group Differences Study Twelve Months Before And Twelve Months During A Worldwide Pandemic, Nancy B. Valla
Patients' Perceptions: A Group Differences Study Twelve Months Before And Twelve Months During A Worldwide Pandemic, Nancy B. Valla
Patient Experience Journal
Objective: The COVID-19 pandemic subjected healthcare systems' to decreasing operational margins, enhanced regulatory scrutiny, and challenges related to patients' expectations. Until now, there was a lack of empirical evidence studying patients' perceptions prior to versus deep immersion into the pandemic. Methods: This quantitative non-experimental ex post facto causal-comparative study examined if and to what extent there were significant differences in patients' perceptions of the nurses' communications, doctors' communications, overall hospital rating, and willingness to recommend before versus during the COVID-19 pandemic for HCAHPS participating hospitals in California. The final sample size was 292 facilities grouped by two identically …
An Exploratory Qualitative Study Of Perinatal Experiences In An Acute Setting During Early Phases Of The Covid-19 Pandemic, Sharon Hoosein, Pamela Winchester, Stephanie Babinski, Naomi Smith, Payalben Bhavsar, Susan Law
An Exploratory Qualitative Study Of Perinatal Experiences In An Acute Setting During Early Phases Of The Covid-19 Pandemic, Sharon Hoosein, Pamela Winchester, Stephanie Babinski, Naomi Smith, Payalben Bhavsar, Susan Law
Patient Experience Journal
The COVID-19 pandemic was highly disruptive for people delivering babies in-hospital and for obstetrical healthcare professionals. The purpose of this study was to explore the experiences of people with or without COVID-19 giving birth in a community-based hospital to provide patient insight to obstetrical care providers regarding the services/policies used during the pandemic. Nine interviews were conducted with participants within six months of giving birth in-hospital – four who tested positive for COVID-19 and five who tested negative. Seven themes were identified in the analysis: conflicting emotions; experiences of COVID-related protocols; altered experiences of pregnancy and birth; other aspects of …
Driving Healthy Behaviors Through Social Support: The Role Of Co-Responsibility In Weight Loss And Maintenance, Melanie Knufinke-Meyfroyt, Carlo Lancia, Yentl Lodewijks, Simon Nienhuijs, Eva Deckers
Driving Healthy Behaviors Through Social Support: The Role Of Co-Responsibility In Weight Loss And Maintenance, Melanie Knufinke-Meyfroyt, Carlo Lancia, Yentl Lodewijks, Simon Nienhuijs, Eva Deckers
Patient Experience Journal
Objective: The effectiveness of out of hospital lifestyle interventions in healthcare is likely co-dependent on social support from involved one's. We sought to investigate the interrelationships between patient-partner Co-responsibility, Spousal Support, and Self-efficacy and the mechanisms through which they contribute to health behaviors and outcomes relevant to weight loss and maintenance. Methods: Co-responsibility, Spousal Support, self-efficacy, health outcomes and health behaviors like total weight loss, physical activity, OBESI-Q, and health satisfaction were assessed through a questionnaire among 868 individuals attempting to lose weight. Full and semi-partial correlations were used to understand the association between Co-responsibility, Spousal Support, Self-efficacy …
Co-Developing A Paediatric Patient Reported Experience Measure: The Perspectives Of Children And Young People, Karlen R. Barr, Jessica Nikolovski, Les White, Sarah Elliott, Lynn Mccartney, Claire Treadgold, Barb Vernon, James R. John, Valsamma Eapen
Co-Developing A Paediatric Patient Reported Experience Measure: The Perspectives Of Children And Young People, Karlen R. Barr, Jessica Nikolovski, Les White, Sarah Elliott, Lynn Mccartney, Claire Treadgold, Barb Vernon, James R. John, Valsamma Eapen
Patient Experience Journal
NOTE: A minor correction was made to this article. It was revised on August 6, 2025.
Paediatric Patient Reported Experience Measures (PREMs) are tools that capture what children and young people (CYP) value in their healthcare and promote their involvement in clinical decision-making. A standardised paediatric PREM could improve quality of care for CYP across hospital settings, but CYP are rarely included in the development of PREMs. This study aimed to explore CYP's perspectives regarding their experiences of hospitals as the initial stage of developing the first self-reported paediatric PREM for use in Australia, including the perspectives of vulnerable populations. …
“You May Not Appreciate This Now, But You May Later”: A Qualitative Analysis Of The Impact And Meaning Of Legacy Interventions As Defined By Bereaved Parents, Stephanie Barta, Cassandra Matz, Stephany Griswold, Foster Rosemund, Caroline Boyd, Sarah Scott, Eileen Auer Bennett, Jennifer Staab
“You May Not Appreciate This Now, But You May Later”: A Qualitative Analysis Of The Impact And Meaning Of Legacy Interventions As Defined By Bereaved Parents, Stephanie Barta, Cassandra Matz, Stephany Griswold, Foster Rosemund, Caroline Boyd, Sarah Scott, Eileen Auer Bennett, Jennifer Staab
Patient Experience Journal
The death of a child is a significant event that affects the family system. Families of dying children need comprehensive support to help them cope with their trauma and loss. However, there is little research that examines parental preferences and grieving support needs. This study explored bereaved parent mentors' perspectives on legacy interventions to identify preferences and guide best practices for legacy interventions provided by pediatric staff. Legacy interventions can be defined as a practice that encourages families to process, create, and reflect on their experiences, stories, and memories. Six parents whose child died ≥2 years ago and who volunteered …
Efficacy Of A Communication Toolkit To Optimize Palliative Care Communication In The Surgical Intensive Unit, Kathryn J. Cary, Aubrey Place, Marta Mccrum, Joanna Grudziak, Lauren Mcguire
Efficacy Of A Communication Toolkit To Optimize Palliative Care Communication In The Surgical Intensive Unit, Kathryn J. Cary, Aubrey Place, Marta Mccrum, Joanna Grudziak, Lauren Mcguire
Patient Experience Journal
Data demonstrates patients benefit from the experience of specialty palliative care providers for advance care planning and prioritizing quality of life, regardless of diagnosis or stage of illness. Despite these benefits, many intensive care units (ICUs) show low utilization of palliative care. The purpose of this study was to evaluate the ability of a bedside communication toolkit to improve communication between family members and caregivers of surgical ICU patients and the ICU team, particularly in the context of medical updates and decision-making. A pilot bedside communication tool was completed by fifty family members of trauma and emergency general surgery (EGS) …
Consumers', Family Members', And Health Practitioners' Perspectives On Increasing Activity Engagement Of Older Patients Admitted To Geriatric Hospital Units, Yvonne Y.K. Mak-Yuen, Farnaz Khoshmanesh, Tamara Tse
Consumers', Family Members', And Health Practitioners' Perspectives On Increasing Activity Engagement Of Older Patients Admitted To Geriatric Hospital Units, Yvonne Y.K. Mak-Yuen, Farnaz Khoshmanesh, Tamara Tse
Patient Experience Journal
The aim of this study was to explore the perspective of consumers, family members, and health practitioners on increasing patient activity engagement in a Geriatric Evaluation and Management (GEM) Unit. This study followed a qualitative phenomenology approach. Semi-structured interviews were conducted, audio-recorded and transcribed verbatim with consenting patients (n = 12), family members (n = 3), and health practitioners (n = 5) admitted to the GEM Unit of a tertiary metropolitan hospital in Melbourne, Victoria, Australia between August 2017 and March 2018. Data were analysed using spiral content analysis. From the 20 interviews, three themes emerged: 1. What can I …
Patient, Family, And Health Professional Perspectives Of How Families Are Involved In Adult Inpatient Traumatic Brain Injury Rehabilitation, Kaylee Eady, Katherine A. Moreau, Shawn Marshall, Mary Egan
Patient, Family, And Health Professional Perspectives Of How Families Are Involved In Adult Inpatient Traumatic Brain Injury Rehabilitation, Kaylee Eady, Katherine A. Moreau, Shawn Marshall, Mary Egan
Patient Experience Journal
Objective: We aimed to answer the following research question: From the perspectives of patients, family members, and health professionals, how are families involved in the rehabilitation of adult patients with Traumatic Brain Injury at an inpatient Acquired Brain Injury service within an adult rehabilitation centre? Methods: We used an interpretive qualitative approach, from a constructivist view. This approach allowed us to understand and describe family involvement from the perspectives of patients with Traumatic Brain Injury, family members, and health professionals. We conducted one-on-one interviews with patients, family members, and health professionals. We used a three-step analysis method: data …
Exploring Consumer And Clinician Attitudes Towards Patient Reported Outcome Measures (Proms) In An Australian Inpatient Musculoskeletal Rehabilitation Unit: A Qualitative Pilot Study, Rehana Di Rico, Louisa Ng, Jacquelin T. Capell
Exploring Consumer And Clinician Attitudes Towards Patient Reported Outcome Measures (Proms) In An Australian Inpatient Musculoskeletal Rehabilitation Unit: A Qualitative Pilot Study, Rehana Di Rico, Louisa Ng, Jacquelin T. Capell
Patient Experience Journal
Objective: This pilot qualitative study explores consumers' and clinicians' perspectives about the relevance and utility of patient reported outcome measures (PROMs) in an Australian inpatient rehabilitation unit. Methods: Two focus groups, were recruited via convenience sampling, comprising English speaking rehabilitation clinicians (n = 5) and consumers (n = 6) who had recent experience of inpatient musculoskeletal rehabilitation in a large, privately funded, rehabilitation hospital in Melbourne Australia, in 2020. The focus groups were conducted via videoconference, moderated by two experienced rehabilitation clinician-researchers, following semi-structured interview guides. Focus group recordings were professionally transcribed for coding and thematic analysis by …
The "Ableism'' Behind Mental Health Professionals' Perceptions Of Support, Hideki Muramatsu
The "Ableism'' Behind Mental Health Professionals' Perceptions Of Support, Hideki Muramatsu
Patient Experience Journal
This paper presents the personal narrative of the author, an individual who has experienced personal and clinical recovery from mental health difficulties. Diagnosed with a mental disorder (NEUROTIC; ICD-10) during my university years, I endured cognitive dysfunction, panic disorder, derangement of ego, suicidal ideation, and depression. Despite these challenges, I have actively engaged in social skills training, supervised virtual reality content, led self-help groups, and published papers on my experiences. I will discuss my own experiences as an expert-by-experience and describe the tendencies of professional ableism consciousness that I encountered during my journey of recovery. Through the lens of my …
Trust Remains The Foundation Of My Practice, Saria Gouher
Trust Remains The Foundation Of My Practice, Saria Gouher
Patient Experience Journal
Navigating healthcare while managing the complexities of disease, especially in elderly individuals, is challenging for both patients and their families. Physicians play a crucial role as pathfinders in this journey. However, physicians often experience burnout when dealing with patients and families facing complex illnesses. This narrative highlights the characteristics that enable physicians to effectively negotiate with such patients. It describes the experience of an elderly patient during the pandemic, suffering from severe disease complications, and illustrates the uncertainties and fears that families face, feeling as though they are lost in a maze. The physician's role in guiding the patient and …
Patient Experience (Px) Giants: Pioneers And The Path Forward, Geoffrey A. Silvera, Courtney Haun, Varun Natarajan
Patient Experience (Px) Giants: Pioneers And The Path Forward, Geoffrey A. Silvera, Courtney Haun, Varun Natarajan
Patient Experience Journal
This commentary pays tribute to the foundational figures in patient experience (PX) scholarship, acknowledging the "PX Giants" whose contributions have established and expanded the field's core principles. Building upon the analysis in Foundational PX, which identified highly cited works, this piece honors individual contributors who have contributed to the scholarly foundation of PX. It highlights the cumulative impact of both frequently cited and consistently productive scholars, underscoring their essential role in shaping patient-centered care. PX Giants have pioneered frameworks on diverse aspects of PX, such as patient-provider communication, care disparities, and the integration of patient perspectives into quality assessments. Through …
Why Human Experience Matters, Jason A. Wolf
Why Human Experience Matters, Jason A. Wolf
Patient Experience Journal
As we close the 11th volume of Patient Experience Journal and a pivotal year for experience efforts globally, it provides a moment of pause, of reflection, and an opportunity to return to purpose. As a publication accessed in over 220 countries and territories around the world, I am heartened by the fact that what is shared on these pages moves you. That what our amazing authors contribute here truly matters. This issue, with its 24 insightful articles, brings our total publication count to 570 articles. These pieces have informed us, pushed our thinking, and challenged our beliefs. This is …
Executive Summary: Staff Education Project Staff Education On Early Screening For Diabetes Among Young Black Adults, Frantz Jacob
Executive Summary: Staff Education Project Staff Education On Early Screening For Diabetes Among Young Black Adults, Frantz Jacob
Walden Dissertations and Doctoral Studies
There are healthcare disparities associated with Type 2 diabetes management in youths, and the condition disproportionately affects racial/ethnic minorities. The gap in practice at the practice site was inconsistent integration of diabetes screening and prevention strategies. The purpose of this project was to develop, implement, and evaluate a staff education program on early screening and prevention of Type 2 diabetes in the young Black community. The practice-focused question centered on whether healthcare staff demonstrated increased knowledge about early screening and prevention for Type 2 diabetes in the young black community. The project occurred at a large family practice clinic in …
Medical School Watercooler Newsletter - November 14, 2024, Lindsay Hughes
Medical School Watercooler Newsletter - November 14, 2024, Lindsay Hughes
Watercooler Newsletter
This is the Thursday, November 14, 2024 edition of the Frederick P. Whiddon College of Medicine's newsletter -- Watercolor.
Contents include:
- Medical student presents poster at annual pathology conference
- Upcoming talk to focus on advancing reproductive advocacy in the South
- Staff recognized for excellence at annual breakfast with the dean
- Cranford to retire from Continuing Medical Education
- Alford joins USA Health OB-GYN and Whiddon COM faculty
Interactive Educational Program For Purposeful Leader Rounding, Gina Lupi
Interactive Educational Program For Purposeful Leader Rounding, Gina Lupi
Walden Dissertations and Doctoral Studies
This education project was to introduce nurse managers to the evidence-based practice of daily purposeful leader rounding on all staff in this acute care facility. The need for practice change was evidenced by low all employee survey and the Survey of Healthcare Experience of Patients (SHEP) results; low retention rates throughout the inpatients units; and an increase of patient safety events in fiscal year 2023. Leadership rounding is an evidence-based practice that increases staff retention by supporting and engaging staff. The purpose of the interactive education was to increase the knowledge and self-confidence of the participants to assist in hardwiring …
A Novel Machine Learning Model To Predict Revision Acl Reconstruction Failure In The Mars Cohort, Kinjal Vasavada, Vrinda Vasavada, Jay Moran, Sai Devana, Changhee Lee, Sharon L. Hame, Laith M. Jazrawi, Orrin H. Sherman, Laura J. Huston, Amanda K. Haas, Christina R. Allen, Daniel E. Cooper, Thomas M. Deberardino, Kurt P. Spindler, Michael J. Stuart, Annunziato Ned Amendola, Christopher C. Annunziata, Robert A. Arciero, Bernard R. Bach, Champ L. Baker, Arthur R. Bartolozzi, Keith M. Baumgarten, Jeffrey H. Berg, Geoffrey A. Bernas, Stephen F. Brockmeier, Robert H. Brophy, Charles A. Bush-Joseph, J. Brad Butler V, James L. Carey, James E. Carpenter, Brian J. Cole, Jonathan M. Cooper, Charles L. Cox, R. Alexander Creighton, Tal S. David, Warren R. Dunn, David C. Flanigan, Robert W. Frederick, Theodore J. Ganley, Charles J. Gatt, Steven R. Gecha, James Robert Giffin, Jo A. Hannafin, Norman Lindsay Harris, Keith S. Hechtman, Elliott B. Hershman, Rudolf G. Hoellrich, David C. Johnson, Timothy S. Johnson, Morgan H. Jones, Christopher C. Kaeding, Ganesh V. Kamath, Thomas E. Klootwyk, Bruce A. Levy, C. Benjamin Ma, G. Peter Maiers, Robert G. Marx, Matthew J. Matava, Gregory M. Mathien, David R. Mcallister, Eric C. Mccarty, Robert G. Mccormack, Bruce S. Miller, Carl W. Nissen, Daniel F. O'Neill, Brett D. Owens, Richard D. Parker, Mark L. Purnell, Arun J. Ramappa, Michael A. Rauh, Arthur C. Rettig, Jon K. Sekiya, Kevin G. Shea, James R. Slauterbeck, Matthew V. Smith, Jeffrey T. Spang, Steven J. Svoboda, Timothy N. Taft, Joachim J. Tenuta, Edwin M. Tingstad, Armando F. Vidal, Darius G. Viskontas, Richard A. White, James S. Williams, Michelle L. Wolcott, Brian R. Wolf, Rick W. Wright, James J. York
A Novel Machine Learning Model To Predict Revision Acl Reconstruction Failure In The Mars Cohort, Kinjal Vasavada, Vrinda Vasavada, Jay Moran, Sai Devana, Changhee Lee, Sharon L. Hame, Laith M. Jazrawi, Orrin H. Sherman, Laura J. Huston, Amanda K. Haas, Christina R. Allen, Daniel E. Cooper, Thomas M. Deberardino, Kurt P. Spindler, Michael J. Stuart, Annunziato Ned Amendola, Christopher C. Annunziata, Robert A. Arciero, Bernard R. Bach, Champ L. Baker, Arthur R. Bartolozzi, Keith M. Baumgarten, Jeffrey H. Berg, Geoffrey A. Bernas, Stephen F. Brockmeier, Robert H. Brophy, Charles A. Bush-Joseph, J. Brad Butler V, James L. Carey, James E. Carpenter, Brian J. Cole, Jonathan M. Cooper, Charles L. Cox, R. Alexander Creighton, Tal S. David, Warren R. Dunn, David C. Flanigan, Robert W. Frederick, Theodore J. Ganley, Charles J. Gatt, Steven R. Gecha, James Robert Giffin, Jo A. Hannafin, Norman Lindsay Harris, Keith S. Hechtman, Elliott B. Hershman, Rudolf G. Hoellrich, David C. Johnson, Timothy S. Johnson, Morgan H. Jones, Christopher C. Kaeding, Ganesh V. Kamath, Thomas E. Klootwyk, Bruce A. Levy, C. Benjamin Ma, G. Peter Maiers, Robert G. Marx, Matthew J. Matava, Gregory M. Mathien, David R. Mcallister, Eric C. Mccarty, Robert G. Mccormack, Bruce S. Miller, Carl W. Nissen, Daniel F. O'Neill, Brett D. Owens, Richard D. Parker, Mark L. Purnell, Arun J. Ramappa, Michael A. Rauh, Arthur C. Rettig, Jon K. Sekiya, Kevin G. Shea, James R. Slauterbeck, Matthew V. Smith, Jeffrey T. Spang, Steven J. Svoboda, Timothy N. Taft, Joachim J. Tenuta, Edwin M. Tingstad, Armando F. Vidal, Darius G. Viskontas, Richard A. White, James S. Williams, Michelle L. Wolcott, Brian R. Wolf, Rick W. Wright, James J. York
Rothman Institute Papers
BACKGROUND: As machine learning becomes increasingly utilized in orthopaedic clinical research, the application of machine learning methodology to cohort data from the Multicenter ACL Revision Study (MARS) presents a valuable opportunity to translate data into patient-specific insights.
PURPOSE: To apply novel machine learning methodology to MARS cohort data to determine a predictive model of revision anterior cruciate ligament reconstruction (rACLR) graft failure and features most predictive of failure.
STUDY DESIGN: Cohort study; Level of evidence, 3.
METHODS: The authors prospectively recruited patients undergoing rACLR from the MARS cohort and obtained preoperative radiographs, surgeon-reported intraoperative findings, and 2- and 6-year follow-up …
The Role Of Sox9 In Epicardial-Mediated Cardiovascular Development And Valve Homeostasis, Andrew Brantley Harvey
The Role Of Sox9 In Epicardial-Mediated Cardiovascular Development And Valve Homeostasis, Andrew Brantley Harvey
MUSC Theses and Dissertations
Congenital heart defects (CHDs) are the most common birth defects in humans, affecting as many as 1% of live births, thereby representing a major public health burden. These defects arise when signaling pathways and mechanical forces guiding heart development are disrupted, either by genetic mutations, aneuploidies, environmental influences, or any combination of these factors. The vast majority of CHDs have undetermined etiologies. Understanding the molecular and cellular mechanisms of normal heart development is critical for unraveling the origins of CHDs and for developing more effective diagnostics and interventional treatments for those affected by cardiovascular diseases of developmental origin.
The epicardium …
Addressing Statistical Challenges In The Analysis Of Proteomics Data With Extremely Small Sample Size: A Simulation Study, Kyung Hyun Lee, Shervin Assassi, Chandra Mohan, Claudia Pedroza
Addressing Statistical Challenges In The Analysis Of Proteomics Data With Extremely Small Sample Size: A Simulation Study, Kyung Hyun Lee, Shervin Assassi, Chandra Mohan, Claudia Pedroza
Faculty, Staff and Student Publications
Background: One of the most promising approaches for early and more precise disease prediction and diagnosis is through the inclusion of proteomics data augmented with clinical data. Clinical proteomics data is often characterized by its high dimensionality and extremely limited sample size, posing a significant challenge when employing machine learning techniques for extracting only the most relevant information. Although there is a wide array of statistical techniques and numerous analysis pipelines employed in proteomics data analysis, it is unclear which of these methods produce the most efficient, reproducible, and clinically meaningful results.
Results: In this study, we compared 9 unique …
Need For Structured Pain Management Curriculum And Competency-Based Evaluation In Gme: An Observational Study In One Internal Medicine Residency Program, Sudhagar Thangarasu, Gowri Renganathan, Barney Soskin, Lela Ruck, Vishakh Prakash, Sumedha Unnikrishnan, Jyothsna Goranti, Everardo Cobos
Need For Structured Pain Management Curriculum And Competency-Based Evaluation In Gme: An Observational Study In One Internal Medicine Residency Program, Sudhagar Thangarasu, Gowri Renganathan, Barney Soskin, Lela Ruck, Vishakh Prakash, Sumedha Unnikrishnan, Jyothsna Goranti, Everardo Cobos
School of Medicine Publications
OBJECTIVES
One of the major contributing factors to the opioid crisis, marked by a surge in opioid prescriptions, includes inadequate adherence to guideline-based pain management practices, highlighting the need for a comprehensive curriculum during residency training. In this study, we aim to assess opioid exposure prevalence among hospitalized patients and examine potential associations between disease conditions, patient demographics, and opioid prescriptions during their hospital stay.
METHODS
In this retrospective cohort study at a southern California county teaching hospital, we analyzed the medical records of 2272 patients admitted to the IM resident inpatient teaching service for 1 year, from September 2017 …
In Vivo Evaluation Of Complex Polyps With Endoscopic Optical Coherence Tomography And Deep Learning During Routine Colonoscopy: A Feasibility Study, Haolin Nie, Hongbo Luo, Vladimir Lamm, Shuying Li, Sanskar Thakur, Chao Zhou, Thomas Hollander, Daniel Cho, Erika Sloan, Jingxia Liu, Pooja Navale, Ahmad N Bazarbashi, Juan Pablo Reyes Genere, Vladimir M Kushnir, Quing Zhu
In Vivo Evaluation Of Complex Polyps With Endoscopic Optical Coherence Tomography And Deep Learning During Routine Colonoscopy: A Feasibility Study, Haolin Nie, Hongbo Luo, Vladimir Lamm, Shuying Li, Sanskar Thakur, Chao Zhou, Thomas Hollander, Daniel Cho, Erika Sloan, Jingxia Liu, Pooja Navale, Ahmad N Bazarbashi, Juan Pablo Reyes Genere, Vladimir M Kushnir, Quing Zhu
2020-Current year OA Pubs
Standard-of-care (SoC) imaging for assessing colorectal polyps during colonoscopy, based on white-light colonoscopy (WLC) and narrow-band imaging (NBI), does not have sufficient accuracy to assess the invasion depth of complex polyps non-invasively during colonoscopy. We aimed to evaluate the feasibility of a custom endoscopic optical coherence tomography (OCT) probe for assessing colorectal polyps during routine colonoscopy. Patients referred for endoscopic treatment of large colorectal polyps were enrolled in this pilot clinical study, which used a side-viewing OCT catheter developed for use with an adult colonoscope. OCT images of polyps were captured during colonoscopy immediately before SoC treatment. A deep learning …
Investigation Of Trimethylenemethane Cyclopentyl-Annulations As A Strategy To Obtain A Functionalized Angular Triquinane Skeleton †, S. M. Webber, Wade A. Russu
Investigation Of Trimethylenemethane Cyclopentyl-Annulations As A Strategy To Obtain A Functionalized Angular Triquinane Skeleton †, S. M. Webber, Wade A. Russu
Pacific Faculty Work
The angular triquinane carbocyclic ring system is a component of many natural products found in numerous terrestrial and marine plants. A strategy for the synthesis of functionalized angular triquinanes utilizing two trimethylenemethane (TMM)-based [3+2] cycloaddition reactions is presented. This synthetic strategy employs the intermolecular dyil-trapping reaction to give eventual access to the bicyclo[3.3.0]oct-1-en-3-one system. A subsequent [3+2] cycloaddition with a TMM equivalent provides the angular triquinane carbocyclic framework.
Systematic Review Of Immune Checkpoint Inhibitor-Related Gastrointestinal, Hepatobiliary, And Pancreatic Adverse Events, Malek Shatila, Hao Chi Zhang, Anusha Shirwaikar Thomas, Antonio Pizuorno Machado, Sidra Naz, Nitish Mittal, Christine Catinis, Krishnavathana Varatharajalu, Carolina Colli Cruz, Eric Lu, Deanna Wu, Julie R Brahmer, Franck Carbonnel, Stephen B Hanauer, Bret Lashner, Bryan Schneider, John A Thompson, Michel Obeid, David P Farris, Yinghong Wang
Systematic Review Of Immune Checkpoint Inhibitor-Related Gastrointestinal, Hepatobiliary, And Pancreatic Adverse Events, Malek Shatila, Hao Chi Zhang, Anusha Shirwaikar Thomas, Antonio Pizuorno Machado, Sidra Naz, Nitish Mittal, Christine Catinis, Krishnavathana Varatharajalu, Carolina Colli Cruz, Eric Lu, Deanna Wu, Julie R Brahmer, Franck Carbonnel, Stephen B Hanauer, Bret Lashner, Bryan Schneider, John A Thompson, Michel Obeid, David P Farris, Yinghong Wang
Faculty, Staff and Student Publications
Gastrointestinal immune-related adverse events (GI irAEs) are common manifestations of immune checkpoint inhibitor (ICI) toxicity. We present a comprehensive systematic review of the incidence, management, and clinical course of irAEs across the entire GI system, including the luminal GI tract, liver, and pancreas. MEDLINE, Embase, Web of Science Core Collection, and Cochrane Library were used to conduct this review. All studies pertaining to GI irAEs were included. Both abstracts and full manuscripts were eligible if they included human subjects and were written in the English language. Articles not available in English, animal studies, or research not specific to GI toxicity …
The Relationship Between Spectral Signals And Retinal Sensitivity In Dendrobatid Frogs, Whitney G. Walkowski, Corinne L. Richards-Zawacki, William C. Gordon, Nicolas G. Bazan, Hamilton E. Farris
The Relationship Between Spectral Signals And Retinal Sensitivity In Dendrobatid Frogs, Whitney G. Walkowski, Corinne L. Richards-Zawacki, William C. Gordon, Nicolas G. Bazan, Hamilton E. Farris
School of Graduate Studies Faculty Publications
Research on visually driven behavior in anurans has often focused on Dendrobatoidea, a clade with extensive variation in skin reflectance, which is perceived to range from cryptic to conspicuous coloration. Because these skin patterns are important in intraspecific and interspecific communication, we hypothesized that the visual spectral sensitivity of dendrobatids should vary with conspecific skin spectrum. We predicted that the physiological response of frog retinas would be tuned to portions of the visible light spectrum that match their body reflectance. Using wavelength-specific electroretinograms (ERGs; from 350-650 nm), spectrometer measurements, and color-calibrated photography of the skin, we compared retinal sensitivity and …
Conference Report: Review Of Clinical Implementation Of Advanced Quantitative Imaging Techniques For Personalized Radiotherapy, Yevgeniy Vinogradskiy, Houda Bahig, Nicholas Bucknell, Jeffrey Buchsbaum, Hui-Kuo George Shu
Conference Report: Review Of Clinical Implementation Of Advanced Quantitative Imaging Techniques For Personalized Radiotherapy, Yevgeniy Vinogradskiy, Houda Bahig, Nicholas Bucknell, Jeffrey Buchsbaum, Hui-Kuo George Shu
Department of Radiation Oncology Faculty Papers
The topic of quantitative imaging in radiation therapy was presented as a "Masterclass" at the 2023 annual meeting of the American Society of Radiation Oncology (ASTRO). Dual-energy computed tomography (CT) and single-positron computed tomography were reviewed in detail as the first portion of the meeting session, with data showing utility in many aspects of radiation oncology including treatment planning and dose response. Positron emission tomography/CT scans evaluating the functional volume of lung tissue so as to provide optimal avoidance of healthy lungs were presented second. Advanced brain imaging was then discussed in the context of different forms of magnetic resonance …
Underutilization Of Influenza Antiviral Treatment Among Children And Adolescents At Higher Risk For Influenza-Associated Complications - United States, 2023-2024., Aaron M. Frutos, Haris M. Ahmad, Dawud Ujamaa, Alissa C. O'Halloran, Janet A. Englund, Eileen J. Klein, Danielle M. Zerr, Melanie Crossland, Holly Staten, Julie A. Boom, Leila C. Sahni, Natasha B. Halasa, Laura S. Stewart, Olla Hamdan, Tess Stopczynski, William Schaffner, H Keipp Talbot, Marian G. Michaels, John V. Williams, Melissa Sutton, M Andraya Hendrick, Mary A. Staat, Elizabeth P. Schlaudecker, Brenda L. Tesini, Christina B. Felsen, Geoffrey A. Weinberg, Peter G. Szilagyi, Bridget J. Anderson, Jemma V. Rowlands, Murtada Khalifa, Marc Martinez, Rangaraj Selvarangan, Jennifer E. Schuster, Ruth Lynfield, Melissa Mcmahon, Sue Kim, Val Tellez Nunez, Patricia A. Ryan, Maya L. Monroe, Yun F. Wang, Kyle P. Openo, James Meek, Kimberly Yousey-Hindes, Nisha B. Alden, Isaac Armistead, Suchitra Rao, Shua J. Chai, Pam Daily Kirley, Ariana P. Toepfer, Fatimah S. Dawood, Heidi L. Moline, Timothy M. Uyeki, Sascha Ellington, Shikha Garg, Catherine H. Bozio, Samantha M. Olson
Underutilization Of Influenza Antiviral Treatment Among Children And Adolescents At Higher Risk For Influenza-Associated Complications - United States, 2023-2024., Aaron M. Frutos, Haris M. Ahmad, Dawud Ujamaa, Alissa C. O'Halloran, Janet A. Englund, Eileen J. Klein, Danielle M. Zerr, Melanie Crossland, Holly Staten, Julie A. Boom, Leila C. Sahni, Natasha B. Halasa, Laura S. Stewart, Olla Hamdan, Tess Stopczynski, William Schaffner, H Keipp Talbot, Marian G. Michaels, John V. Williams, Melissa Sutton, M Andraya Hendrick, Mary A. Staat, Elizabeth P. Schlaudecker, Brenda L. Tesini, Christina B. Felsen, Geoffrey A. Weinberg, Peter G. Szilagyi, Bridget J. Anderson, Jemma V. Rowlands, Murtada Khalifa, Marc Martinez, Rangaraj Selvarangan, Jennifer E. Schuster, Ruth Lynfield, Melissa Mcmahon, Sue Kim, Val Tellez Nunez, Patricia A. Ryan, Maya L. Monroe, Yun F. Wang, Kyle P. Openo, James Meek, Kimberly Yousey-Hindes, Nisha B. Alden, Isaac Armistead, Suchitra Rao, Shua J. Chai, Pam Daily Kirley, Ariana P. Toepfer, Fatimah S. Dawood, Heidi L. Moline, Timothy M. Uyeki, Sascha Ellington, Shikha Garg, Catherine H. Bozio, Samantha M. Olson
Manuscripts, Articles, Book Chapters and Other Papers
Annually, tens of thousands of U.S. children and adolescents are hospitalized with seasonal influenza virus infection. Both influenza vaccination and early initiation of antiviral treatment can reduce complications of influenza. Using data from two U.S. influenza surveillance networks for children and adolescents agedattended, laboratory-confirmed influenza for whom antiviral treatment is recommended, the percentage who received treatment was calculated. Trends in antiviral treatment of children and adolescents hospitalized with influenza from the 2017-18 to the 2023-2024 influenza seasons were also examined. Since 2017-18, when 70%-86% of hospitalized children and adolescents with influenza received antiviral treatment, the proportion receiving treatment notably declined. …