Medicine and Health Sciences Commons^™

The Potential Therapeutic Effect For Melatonin And Mesenchymal Stem Cells On Hepatocellular Carcinoma, Yasser Mohamed, Mohamed A. Basyony, Nabila I. El-Desouki, Walied S. Abdo, Mohammed A. El-Magd

BioMedicine

Background/aim: Herein, we investigated the potential therapeutic effect of Melatonin (Mel) and/or mesenchymal stem cells (MSCs) on rat model of HCC.

Materials and Methods: Female mature rats were divided into 5 groups (n= 10/group): normal (Nor), HCC group intraperitoneally injected with 200 mg/kg DEN, and 3 treated groups; HCC + Mel (Mel) group given Mel intraperitoneally 20 mg/kg, twice a week, HCC + MSCs (MSCs) group intravenously injected by 1 × 10⁶ cells, and HCC + MSCs (Mel +MSCs) group.

Results: Rats in HCC group showed most deteriorated effect in form of increased mortality and relative liver weight, elevated …

Immunohistochemical Expression Of P53, Ki-67, And Cd34 In Psoriasis And Psoriasiform Dermatitis, Mazaher Ramezani, Atefeh Shamshiri, Elisa Zavattaro, Sedigheh Khazaei, Mansour Rezaei, Rozhano Mahmoodi, Masoud Sadeghi

BioMedicine

Background: Psoriasis is the prime example of psoriasiform tissue pattern and should be differentiated from other psoriasiform dermatoses both clinically and histopathologically.

Aim: To evaluate immunohistochemical expression of P53, Ki-67, and CD34 in psoriasis and psoriasiform dermatitis for diagnostic purposes.

Methods: An analytical cross-sectional study was performed on the paraffin blocks of 60 psoriasis and 31 psoriasiform dermatitis patients between 2014 and 2017. The selected formalin-fixed paraffin-embedded tissues from each biopsy specimen were cut into 4-micron sections. Initial sections were stained by hematoxylin and eosin staining. Primary antihuman antibodies against P53, Ki-67, and CD34 were applied. Positive control samples for …

The Judet Quadricepsplasty For Elderly Traumatic Knee Extension Contracture: A Case Report And Review Of The Literature, Benjamin Tze Keong Ding, Suheal Ali Khan

BioMedicine

Traumatic injuries to the knee are frequently complicated by extension contractures. The Judet Quadricepsplasty allows for controlled, sequential release of extrinsic and intrinsic knee contracture components while reducing the potential for iatrogenic quadriceps rupture. We document our institutions experience with this procedure and a systematic review of the current literature. We followed up on an elderly patient with posttraumatic flexion contracture that failed conservative management and underwent Judet Quadricepsplasty. Her knee range of motion improve dramatically from 20 degrees of flexion to 100 degrees of flexion. There was a residual extension lag of 5 degrees which did not impede on …

Cohort Study Of Microelement Status In “Healthy” Population Of Russian Megapolis, Andrew K. Martusevich, Konstantin A. Karuzin

BioMedicine

The aim of the study was at the cohort assessment of microelement status in large city residents classified as “apparently healthy people”. The population study included 2,025 randomly selected middle-aged (2045 years) persons without chronic diseases or acute infectious pathologies. The set of subjects was standardized by age and gender. A blood sample was taken once from each person to determine concentrations of microelements. The level of peripheral blood microelements were determined by atomic absorption spectrometry using «Shimadzu AA7000» device (Japan). The study of a large population of city residents demonstrated inhomogeneity in their microelement status. Deficit conditions were found …

Awareness On Breast Cancer Screening In Malaysia: A Cross Sectional Study, Mun-Seng Lee, Choiriyatul ‘Azmiyaty Amar Ma’ Ruf, Dayang Puteri Nadhirah Izhar, Sayyida Nafisah Ishak, Wan Syazana Wan Jamaluddin, Syafiqah Nadiah Mohd Ya’Acob, Muhammad Nazrullah Kamaluddin

BioMedicine

Introduction: The increasing rate of breast cancer (BC) incidence in Malaysia hints a lack of awareness among Malaysians. One (1) woman out of nineteen (19) is at risk with BC and almost up to fifty percent (50%) of women diagnosed with BC were reported to be under the age of fifty (50). Our main concern is to study the level of awareness among the women on risk factors, clinical manifestations, diagnosis, preventions and treatments.

Method: A cross-sectional study was conducted exclusively among women in the public with total sample of three hundred and forty six (346), questionnaires were distributed using …

Evaluation Of The Serum Β2 Microglobulin Level In Patients With Systemic Lupus Erythematosus And Its Correlation With Disease Activity, Miramir Aghdashi, Simak Salami, Ahmad Nezhadisalami

BioMedicine

Background: Designation of disease activity is serious for the management of systemic lupus erythematosus (SLE). Serum level of β2 microglobulin (β2M) may be associated with illness activity in SLE disease. Since the role of β2M for assessing of illness activity in SLE is not completely clear, the current study aimed to discern evaluation of β2M in patients with SLE and its correlation with sickness activity.

Materials and Methods: In this case-control study, 50 patients with SLE disease and 25 healthy individuals were selected in Imam Khomeini Hospital in central of Urmia.

Blood samples were collected safely from patients, serum was …

The Effect Of NigellaSativaOil On The Prevention Of Phlebitis Induced By Chemotherapy: A Clinical Trial, Niaz Behnamfar, Zohreh Parsa Yekta, Faraz Mojab, Seyyed Mohammad Kazem Naeini

BioMedicine

Introduction: Phlebitis, that disrupts chemotherapy, is the inflammation of the vein and the most common complication of intravenous injection of chemotherapy drugs.

Aim: the aim was determine the effect of topical application of N.sativaoil on the prevention of phlebitis caused by chemotherapy.

Methods: This single-blind clinical trial was conducted on 60 cancer patients. In the intervention group, five drops of N.sativaoil was applied on the distal area of the catheter, two times per day and every 12 hours from the first day of chemotherapy to the third day; no intervention was conducted for the subjects in the control group.

Results: …

The Prevalence Of Post-Traumatic Stress Disorder Among Emergency Nurses: A Cross Sectional Study In Northern Iran, Seyed Mohammad Hosseininejad, Fatemeh Jahanian, Forouzan Elyasi, Hossein Mokhtari, Mohammad Eslami Koulaei, Seyedeh Masoumeh Pashaei

BioMedicine

Background and objective: Posttraumatic stress disorder (PTSD) is one of the anxiety disorders which occurs in response to facing events and accidents accompanied by fear, frustration, and terror. Nurses who worked in the emergency departments witness unpleasant accidents and are exposed to stress and violence more than others. The aim of this study was to investigate the prevalence of PTSD among Iranian nurses working in the emergency department.

Materials and Methods: In this cross-sectional study, all nurses working in the emergency department of educational hospitals affiliated with Mazandaran University of Medical Sciences were included through census method (n = 131). …

Development Of Broad Spectrum Mycosporine Loaded Sunscreen Formulation From Ulva Fasciata Delile, Saurabh Bhatia, Satish Sardana, Ajay Sharma, Celia Bertha Vargas De La Cruz, Bhupal Chaugule, Laleh Khodaie

BioMedicine

Ba.ckground: Sunscreen formulations primarily offer protection against UV induced damages however nowadays it also maintains skin natural physiological conditions. Current global market is flooded with numerous sunscreen products which offer protection to skin against several UV induced damages. However most of these sunscreen formulations offers narrow spectrum protection against UV and also suffer from stability as well as toxicity related issues.

Methods: Present work aims to isolate mycosporine amino acid (Mgy) from green alga namelyUlva fasciata (U. fasciata)and study its sunscreen potential against widely used domestic marketed formulation. Stability evaluations were also performed for almost 90 days.

Results: Results demonstrated …

Fascioliasis Mimicking Malignancy In An Old Patient, Mazaher Ramezani, Farhad Amirian, Masoud Sadeghi

BioMedicine

No abstract provided.

Protective Effect OfGlycyrrhiza GlabraRoots Extract On Bone Mineral Density Of Ovariectomized Rats, Dimitrios Galanis, Konstantinos Soultanis, Pavlos Lelovas, Alexandros Zervas, Panagiotis Papadopoulos, Antonis Galanos, Katerina Argyropoulou, Maria Makropoulou, Anastasia Patsaki, Christina Passali, Anastasia Tsingotjidou, Stavros Kourkoulis, Sofia Mitakou, Ismene Dontas

BioMedicine

Objective: The aim of this study was to evaluate the potential effect of the methanolic extract of plantGlycyrrhiza glabraroots on bone mineral density and femoral bone strength of ovariectomized rats.

Methods: Thirty 10-month-old Wistar rats were randomly separated into three groups of ten, Control, Ovariectomy and Ovariectomy-plus-Glycyrrhiza in their drinking water. Total and proximal tibial bone mineral density was measured in all groups before ovariectomy (baseline) and after 3 and 6 months post ovariectomy. Three-point-bending of the femurs and uterine weight and histology were examined at the end of the study.

Results: No significant difference was noted in bone density …

Ossification Of The Yellow Ligament In The Cervical Spine – An Unusual Location, Jacob Yoong-Leong Oh, Victor Tzong-Jing Wang, Timothy Wei Wen Teo, Arun-Kumar Kaliya-Perumal, Hwan Tak Hee

BioMedicine

Ossification of the yellow ligament (OYL) or ligamentum flavum, usually occurs in the thoracic spine. Focal OYL occurring in the cervical spine is considered rare and is sparsely reported in the literature. We came across a 30-year-old male patient with progressive left upper limb and bilateral lower limb weakness over a period of 3 months, associated with an unsteady gait. Clinical examination revealed bilateral generalized hyper-reflexia in both upper and lower limbs, inverted supinator jerk, Hoffman’s sign and clonus. Myelopathy due to cord compression was suspected and further investigations were done. MRI and CT scans revealed a bony mass in …

In Vivo Microdialysis And In Vitro Hplc Analysis Of The Impact Of Paeoniflorin On The Monoamine Levels And Their Metabolites In The Rodent Brain, Yuh-Tzy Lin, Wei-Shih Huang, Huei-Yann Tsai, Min-Min Lee, Yuh-Fung Chen

BioMedicine

Background: Paeoniflorin (PF) possesses several effects such as analgesic, the anti-spasmodic effect on smooth muscle. It protects the cardiovascular system and reveals the neuroprotective effect on cerebral ischemia. Monoamine system has been identified to have complex regulatory effects in pain signaling. There are no reports regarding the impact of PF on monoamine levels in the rodent brain by microdialysis. In this study, the effects of PF on monoamines and their metabolites in the rodent brain usingin vivomicrodialysis andin vitrohigh performance liquid chromatography (HPLC) analysis.

Methods: Male S.D. rats were anesthetized, fixed onto the stereotaxic instrument to identify the positions of …

Gynura BicolorAqueous Extract Attenuated H2O2Induced Injury In Pc12 Cells, Ya-Chen Yang, Wen-Tzu Wu, Mei-Chin Mong, Zhi-Hong Wang

BioMedicine

Background: Protective effects ofGynura bicoloraqueous extract (GAE) at three concentrations upon nerve growth factor (NGF) differentiated-PC12 cells against H₂O₂induced injury were examined.

Methods: NGF differentiated-PC12 cells were treated with GAE at 0.25%, 0.5% or 1%. 100 μM H₂O₂was used to treat cells with GAE pre-treatments. After incubating at 37 °C for 12 hr, experimental analyses were processed.

Results: H₂O₂exposure decreased cell viability, increased plasma membrane damage, suppressed Bcl-2 mRNA expression and enhanced Bax mRNA expression. GAE pre-treatments reversed these changes. H₂O₂exposure reduced mitochondrial membrane …

Applying Wcacg Modified Process Is Beneficial On Reduced Door-To-Balloon Time Of Acute Stemi Patients, Qiao-Wen Li, Xiao-Jian Liu, Jin-Hua Li, Guo-Qi Zhang, Su-Min Chen, Chao-Long Huang, Min Qiu, Yue-Liang Li, Peng Duan, Yi-Jiun Weng, Xiao-Yong Zhang, Chih-Yang Huang

BioMedicine

Background: Various systems have employed with the objective to reduce the time from emergency medical services contact to balloon inflammation for ST-elevation myocardial infraction (STEMI) patients. The WCACG message system was used to an alternative communication platform to improve confirmation of the diagnosis and movement to treatment, resulted in shorten the door-to-balloon (D-to-B) time for STEMI patients.

Methods: We collected 366 STEMI patients admitted at the Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People’s Hospital, Department of Cardiology, during the period from June 2013 to October 2015. The patients were divided into two groups one underwent the current GC …

Monomicrobial Non-Neutrocytic Bacterascites Caused By Aeromonas Hydrophila In A Patient With Liver Cirrhosis, Chen-Sheng Lin, Cheng-Wen Lin

BioMedicine

Aeromonas peritonitis is a rare, but serious infection, as associated with spontaneous bacterial peritonitis, peritonitis in chronic ambulatory peritoneal dialysis, and intestinal perforation. Here, we reported a case of monomicrobial non-neutrocytic bacterascites caused by Aeromonas hydrophila (A. hydrophila). The patient, a 57-year-old man who had a history of alcoholic liver disease and chronic hepatitis C-related Child- Pugh class C liver cirrhosis, was admitted to our hospital with fever, dyspnea and a localized wound pain over left ankle. Ascitic fluid analysis demonstrated that ascitic polymorphonuclear cell count was 30 cells/ mm³. Empirical antimicrobial treatment with a combination of ceftriaxone …

Comparative Study Of The Effect Of Thymus Daenensis Gel 5% And Diclofenac In Patients With Knee Osteoarthritis, Morteza Dehghan, Shirin Asgharian, Elena Khalesi, Ali Ahmadi, Zahra Lorigooini

BioMedicine

Background: Osteoarthritis is a syndrome characterized by joint pain and reduced performance and efficien- cy in patient.Thymus daenensishas been used since old times for the treatment of bone and joint deformities and pain in traditional medicine.

Purpose: This study was conducted to examine traditional usages and pharmacological features ofT. daen- ensiswith respect to the effect of the plant in patients with osteoarthritis.

Methods: 120 patients with osteoarthritis were divided into 3 groups. Patients in each group were treated by 5%Thymus daenensisgel, 1% diclofenac gel, or placebo for 6 weeks, along with oral celecoxib capsules. Patients were assessed in different intervals, …

The Relationship Between Body Mass Index (Bmi) And Quality Of Life In Iranian Primary School Students In Tehran, Iran, Mostafa Farajpour. Kh, Mohadeseh Pishgahroodsari, Hamid Salehiniya, Fahimeh Soheilipour

BioMedicine

No abstract provided.

Alabama Agricultural Producers’ Experiences With Wild Pigs (Sus Scrofa) And Their Preferences Concerning Wild Pig Management, Hailey E. Ellis, Luren M. Jaebker, Alan D. Bright, Mark D. Smith, Keith M. Carlisle

United States Department of Agriculture Wildlife Services: Staff Publications

Government agencies and landowners use a variety of lethal methods to reduce invasive wild pig populations and resulting agricultural damages. To provide decision-makers with information regarding Alabama farmers’ experiences with wild pigs and their preferences for management actions, we surveyed Alabama Farmers Federation members in 2020. We found that wild pigs were commonly present on livestock, timber, and crop production acreage, but wild pig damages and costs were much more common among crop producers. Respondents' wildlife acceptance capacity for wild pigs was low and all lethal control methods were considered aceptable by most reposndents, particularly those performed by landowners. While …

Graphic Medicine, Leesha Coleman, Rachel F. Fenske, Quincy Roundtree

Creative Arts & Storytelling for Health and Wellness Summit

Attendees will get an overview of graphic medicine, hear about the history of graphic medicine at the Charles M. Baugh Biomedical Library, learn about the artistic process of creating comics, and hear about uses for graphic medicine in educational and clinical settings.

2024 Graduate Research Day Agenda (Pdf), Graduate Studies

Dr. Joseph M. Moerschbaecher, III Graduate Research Day

The 3rd Annual Dr. Joseph Moerschbaecher, III Graduate Research Day Agenda (PDF)

The Art Of Medicine: Healing The Heart, Body And Soul, T. J. Hundley, Peyton Mcelroy

Creative Arts & Storytelling for Health and Wellness Summit

In this session, we will explore the various ways in which literary, visual, and performing arts serve within medical communities to create meaning and understanding from the profound human experiences associated with illness, healing, and health. We will discuss the relationship between the creative arts, reflective practice, and professional identity. Furthermore, we will demonstrate how the creative arts can be effectively utilized to promote reflective practice.

The Effect Of Exercise Type On Working Memory, Ariana Gonzalez, William R. Kochen

Journal for Sports Neuroscience

Martial arts encompass a wide range of sports and techniques that have been practiced for self-defense and combat for thousands of years. It has expanded to include various styles such as Brazilian Jiu-Jitsu, Taekwondo, judo, and karate. It has also been practiced as a form of exercise and entertainment. Martial arts have been associated to discipline, integrity, improved stamina, and increased mental and problem-solving capabilities. Unlike other exercise methods, most martial arts require focus, skill, and technique, which have been hypothesized to improve memory. The purpose of the study was to determine if there was a significant improvement in the …

A Case Study On The Impact Of An Adapted Community Jury In Shaping The Nutrition Standards For Hospital Menus In New South Wales Australia, Tara L. Dimopoulos-Bick, Melanie Schier, Kim Crawley, Kim Sutherland

Patient Experience Journal

Community juries are a form of deliberative democracy and can engage community groups in decision-making about healthcare and service delivery issues and priorities. They can provide insights and value-based perspectives from community groups and are particularly important in resolving perennial and complex system challenges. One such challenge is nutrition in hospitals–where there is a need to balance nutrition support, variety, taste and cost. The New South Wales (NSW) public health system in Australia operates more than 200 public hospitals. When revising the Nutrition Standards in 2021, stakeholders debated the upper limits of sodium (salt) and saturated fat in food products …

Patient Engagement And Co-Creation In Healthcare Services: A Scoping Review, Thiruppavai Sundaramurthi, Smita Mathews, Ella Bermudez, Satish M. Mahajan

Patient Experience Journal

Objective: The objective of this review was to find literature related to the concepts of patient engagement and co-creation in healthcare services and identify models and/or frameworks that combined these concepts. Methods: We developed the eligibility criteria using the Population-Concept-Context framework applicable to studies with population of patients exploring the concepts of engagement and co-creation in the context of healthcare services. The search was conducted in PubMed, CINAHL, Cochrane, APA PsycINFO, and Ovid MEDLINE. We searched for articles in English with no search limitations on publication dates. Reviewers screened abstracts and full texts to identify articles for data …

Factors Influencing Patient Satisfaction With Zambia's National Health Insurance Scheme: A Systematic Literature Review Using Empirical Evidence From Nigeria And Ghana, Wesley Kapaya Mwambazi, Abubaker Qutieshat

Patient Experience Journal

Universal Health Coverage (UHC) has become important for African nations as they strive to provide equitable healthcare access to all citizens. Implementing a successful National Health Insurance Scheme (NHIS) is crucial to achieving this goal. In pursuit of achieving UHC, Zambia launched the NHIS in 2019 with the ambitious goal of reaching 100% coverage by 2021. Some of those enrolled had reported varying levels of satisfaction with the NHIS services. Understanding patient satisfaction with NHIS-provided services is therefore essential for improving its implementation and enhancing NHIS patient satisfaction. Following PRISMA guidelines, a systematic review of empirical studies from Nigeria and …

Patient Safety Culture Among Healthcare Settings In Low And Middle-Income Countries: A Systematic Review And Meta-Analysis, Natnael Atnafu Gebeyehu, Kirubel Dagnaw Tegegne, Biruk Adie Admass, Nathan Estifanos Shewangashaw, Yibeltal Assefa Atalay, Dagne Adisu Sewuyew, Awoke Elefachew Gebremariam, Kelemu Abebe Gelaw

Patient Experience Journal

Ensuring patient safety is a crucial element in providing high-quality healthcare services. Therefore, this study aimed to assess the current state of patient safety culture in healthcare settings within low- and middle-income countries. A thorough search was conducted across multiple databases, including Science Direct, Scopus, Google Scholar, EMBASE, and PubMed. Data extraction was carried out using Microsoft Excel, and statistical analysis was performed using STATA software (version 14). To evaluate publication bias, methods such as Egger's regression tests, rank tests, and forest plots were utilized. The I2 statistic was used to assess heterogeneity, followed by an overall estimated analysis. Additionally, …

Quality Of Outpatient Care In Lebanon: A Cross-Sectional Survey, Georges Choueiry, Anna Maria Henaine, Rayan Darwish, Pascale Salameh

Patient Experience Journal

Patient experience is an important driver of healthcare improvement. Yet, in Lebanon, there is a lack of studies focusing on the satisfaction of outpatients with healthcare quality. This study aims to assess the quality of outpatient care in Lebanon from the patient’s perspective and identify its determinants. A cross-sectional survey was administered, between December 2023 and January 2024, to 265 participants over 18 years old who consulted a healthcare provider, excluding dentists. We used linear regression to determine factors affecting consultation quality as perceived by the participants. Waiting time before consultations typically ranged from 5 to 15 minutes, the average …

Experiences Of Using Electronic Medical Records Among Patients From Ethnic Minority Backgrounds: A Rapid Review, Corey Adams, Reema Harrison, Alison Merchant, Narelle Arblaster, Tracey Bucknall, Kathleen Gray, Guncag Ozavci, Nilmini Wickramasinghe, Vicky Yuan, Elizabeth Manias

Patient Experience Journal

This study explores the experiences of individuals from ethnic minority backgrounds using electronic medical records (EMRs) and identifies strategies to improve the inclusivity and usability of EMRs, aiming to reduce the digital divide in their access and use. A rapid review of the literature was conducted using Medline, Embase, and CINAHL databases to identify relevant studies published between 2010 and November 2023, with the assistance of a medical librarian.

A total of 44 studies were included in the review, revealing significant disparities in EMR adoption and utilization among ethnic minority groups. Three key themes of inequality were identified: presentation of …

Laboratory Literacy: Surveying Lab Result Interpretations Of A Local Patient Population, Jordan Franco, Mark K. Fung

Patient Experience Journal

A patient's independent interpretation of their medical laboratory data has become an unspoken prerequisite in the current age of medicine. In the outpatient setting, it is anecdotally commonplace for patients to receive their lab results before their physicians, resulting in patients often relying on self-interpretations of their results. This study analyzed the degree to which patients are comfortable interpreting lab results and sought to shed light on the question: How are patients interpreting their laboratory reports? A survey was constructed to include the items from a validated health literacy screening tool, followed by items inquiring about the respondent's experience and …