Medicine and Health Sciences Commons^™

The Effectiveness Of Using The Nordic Walking Wellness Exercise In Extracurricular Time Of Primary School Students, Mirzohid Mirzolim Ogli Azizov

Eurasian Journal of Sport Science

Purpose: to increase the level of comprehensive harmonious development and preparedness of primary school students in their free time from the lesson using the method of Nordic walking.

Methods: Analysis and generalization of scientific and methodological literature; pedagogical test; medical and biological methods; pedagogical experiment; methods of mathematical statistics.

Results: The results obtained as a result of the “Cooper test” showed that before the experiment in CG, the average value was 1115.3±118.2 meters, at the end of the experiment it was 1168.2±122.1 meters, or the rate of endurance growth was statistically unreliable and equal to 52.9 meters (t=2.6 and p …

Stop The Beat To See The Rhythm: Excitation-Contraction Uncoupling In Cardiac Research., Luther M Swift, Matthew W. Kay, Crystal M Ripplinger, Nikki Gillum Posnack

Pediatrics Faculty Publications

No abstract provided.

Forward Together Update [Delta Variant, Panther Health Survey, & Flu Clinics], December 7, 2021, University Of Northern Iowa

UNI Response to COVID-19

Reminds that the Delta variant of COVID-19 is the main variant circulating in the United States, the process for submitting a voluntary vaccine verification, and who should fill out the Panther Health Survey. Also announces the addition of two flu shot clinics on campus.

Links To Weekend Booster Clinics (12/11 And 12/12), The Coronavirus Planning Team

University Briefings & Virtual Events

These clinics will be expanded to 200 slots. The link will stop working when the clinic is full.

Ketone Body Metabolism In The Ischemic Heart, Stephen C. Kolwicz Jr.

Health Sciences Faculty Publications

Ketone bodies have been identified as an important, alternative fuel source in heart failure. In addition, the use of ketone bodies as a fuel source has been suggested to be a potential ergogenic aid for endurance exercise performance. These findings have certainly renewed interest in the use of ketogenic diets and exogenous supplementation in an effort to improve overall health and disease. However, given the prevalence of ischemic heart disease and myocardial infarctions, these strategies may not be ideal for individuals with coronary artery disease. Although research studies have clearly defined changes in fatty acid and glucose metabolism during ischemia …

Implementation Of Strategic Supports Into Coursework To Improve Notetaking Abilities And Overall Ota Student Success, Cheyenne M. Murphy

Department of Occupational Therapy Entry-Level Capstone Projects

Notetaking is a widespread practice utilized by students to capture valuable information mentioned throughout lectures, readings, and other supplementary instruction. Practices of notetaking can vary based on educational level and the student’s ability to take notes throughout their educational career. More specifically, the ability to take strategic notes is recognized as an important skill needed in a higher educational setting in relation to a students’ overall success (Salame & Thompson, 2020). When examining the effect of notetaking, earlier studies focused solely on the practice and utilization of notetaking (Rahmani & Sadeghi, 2011). The objective of this culminating project is research …

Using A Social Support Group To Educate And Empower Immigrant Latina Women, Diana N. Rendon

Department of Occupational Therapy Entry-Level Capstone Projects

The purpose of this capstone project was to promote mental health education and access to vulnerable South Florida Latina Women. The original intent was to establish a program providing families with mental health education, including information about common mental illnesses, signs and symptoms, community resources, and the impacts on occupations. This capstone experience was conducted with the Magnolias Women's Support Group at Caridad Center, located in Palm Beach County, Florida. The focus areas of this capstone were advocacy, policy and program development, and administration. Furthermore, this capstone project was intended to promote health literacy for underserved populations, especially immigrant women.

Nerve Impairment In Burn Injuries, Taylor A. Kowalske

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.

The Role Of Pre-Participation Exams In Identifying Student Athletes At Risk For Sudden Cardiac Arrest, Elizabeth Frey

Honors Projects

Sudden cardiac arrest (SCA) is the leading cause of death in young student athletes (Drezner et al., 2007). With athletes being recognized as some of the healthiest members of society, a catastrophic event like this can stimulate debate over pre-participation screening and appropriate emergency actions. With 55-80% cases of sudden cardiac death (SCD) being asymptomatic before the event (Drezner et al., 2007), looking into how well pre-participation screenings identify at risk individuals becomes much more important. This project investigates to what extent pre-participation physicals (PPE) can be improved to better identify student athletes at risk for sudden cardiac death and …

Sox10 Requirement For Melanoma Tumor Growth Is Due, In Part, To Immune-Mediated Effects, Sheera Rosenbaum, Manoela Tiago, Signe Caksa, Claudia Capparelli, Timothy J. Purwin, Gaurav Kumar, Mckenna Glasheen, Danielle Pomante, Daniel Kotas, I Chervoneva, A E Aplin

Department of Cancer Biology Faculty Papers

Developmental factors may regulate the expression of immune modulatory proteins in cancer, linking embryonic development and cancer cell immune evasion. This is particularly relevant in melanoma because immune checkpoint inhibitors are commonly used in the clinic. SRY-box transcription factor 10 (SOX10) mediates neural crest development and is required for melanoma cell growth. In this study, we investigate immune-related targets of SOX10 and observe positive regulation of herpesvirus entry mediator (HVEM) and carcinoembryonic-antigen cell-adhesion molecule 1 (CEACAM1). Sox10 knockout reduces tumor growth in vivo, and this effect is exacerbated in immune-competent models. Modulation of CEACAM1 expression but not HVEM elicits modest …

2021-12-07_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …

Treatment Of Full-Thickness Acetabular Chondral Flaps During Hip Arthroscopy: Bone Marrow Aspirate Concentrate Versus Microfracture, Michael P. Kucharik, Paul F. Abraham, Mark R. Nazal, Nathan H. Varady, Christopher T. Eberlin, Wendy M. Meek, Sara A. Naessig, Scott D. Martin

Orthopaedic Surgery and Sports Medicine Resident Research

Background: The optimal treatment strategy for patients with full-thickness chondral flaps undergoing hip arthroscopy is controversial.

Purpose: To compare functional outcomes of patients who underwent bone marrow aspirate concentrate (BMAC) application with those of patients who underwent microfracture.

Study Design: Cohort study; Level of evidence, 3.

Methods: This was a retrospective case series of prospectively collected data on patients who underwent arthroscopic acetabular labral repair by 1 surgeon between June 2014 and April 2020. The inclusion criteria for this study were age ≥18 years, preoperative radiographs of the pelvis, arthroscopic acetabular labral repair, exposed subchondral bone with overlying chondral flap …

Covid-19 Newsletter (Vol. 98), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Potential Effects Of Animatronic Pet Ownership In College Students, Bayleigh Burling

Honors Theses

No abstract provided.

Baphia Macrocalyx Leaf Extract Attenuates Rotenone-Induced Toxicity In Drosophila Melanogaster Model Of Parkinson’S Disease, Flora Stephano

Journal of Humanities and Social Sciences

Parkinson’s disease (PD) is a motor disorder mostly affecting aged people, with not known standard therapy. The use of natural products is increasingly gaining attention for the treatment of different diseases. Baphia macrocalyx is a plant previously associated with antioxidant activities in in vitro studies. Thus, the aim of this study was to evaluate the ameliorative potential of methanolic leaf extract of Baphia macrocalyx (MEBM) on rotenone-triggered toxicity in Drosophila melanogaster. To this end, the study used a neurotoxin, rotenone, to induce PD in the fruit-fly to create a chemical PD in vivo model. Using biochemical, behavioural and molecular analyses, …

Adverse Childhood Experiences: Effects Of Covid-19, Evan Guo

Honors Projects

The evaluation of an adult's health status consists of several entities. These factors can include physical, mental, and emotional health in an individual's history contributing to their overall health. When studying such factors, some researchers emphasize the importance of recognizing events experienced during a person's childhood that affect their development, and therefore, their adult health status. Today, as people continue adapting to the COVID-19 pandemic and changes in regulation of standards for socialization, it is becoming apparent to healthcare researchers how these new modifications are highly impactful to the development of children and adolescents. When studying the various factors that …

Keratin 1 As A Cell-Surface Receptor In Cancer, Oluseye Ogunnigbagbe, Christopher G. Bunick, Kamaljit Kaur

Pharmacy Faculty Articles and Research

Keratins are fibrous proteins that take part in several important cellular functions, including the formation of intermediate filaments. In addition, keratins serve as epithelial cell markers, which has made their role in cancer progression, diagnosis, and treatment an important focus of research. Keratin 1 (K1) is a type II keratin whose structure is comprised of a coiled-coil central domain flanked by flexible, glycine-rich loops in the N- and C-termini. While the structure of cytoplasmic K1 is established, the structure of cell-surface K1 is not known. Several transformed cells, such as cancerous cells and cells that have undergone oxidative stress, display …

Efficacy Of Live Attenuated Dengue Vaccines: Cyd-Tdv, Tdv (Tak-003), And Tv003/Tv005, Yoseph Jeffry Hertanto, Bernadette Dian Novita

Folia Medica Indonesiana

Highlight: • Differences in the efficacy of CYD-TDV versus the other TAK-003 and TV003/TV005 were discussed. • One licensed dengue vaccine is CYD-TDV (Dengvaxia). Abstract: Dengue fever is the most common tropical disease, but there still remains no specific therapy that can overcome it. Special attention needs to be paid to this disease, because there were large increases in incidence in the last decade. As an effective preventive strategy, finding a new vaccine for dengue fever with higher potentiation and efficacy is highly necessary to stop dengue transmission especially in the endemic area. Vaccine triggers an immune response, so that …

Examination Of Covid-19 And The Spanish Flu Of 1918, Caden A. Striegle

Honors Projects

COVID-19, for many across the globe, has been a pandemic the likes of which has never been seen before. It has caused many aspects of life to change in order to adapt to the new limitations and cautions brought about by the global spread of a novel virus. However, almost exactly 100 years prior, a strain of the H1N1 influenza virus also known as the Spanish Flu of 1918, similarly uprooted life for millions of people around the globe. These two pandemics, while similarly leading to great disruption of global health, had many differences in the demographics impacted as well …

Experiences Of African American Women Living With Herpes Simplex Virus 2, Cherlisa Jackson, Yitza A. Arcelay-Rojas

Journal of Social, Behavioral, and Health Sciences

In the United States, the prevalence of herpes simplex virus 2 (HSV-2) continues to be the highest among African American women. Yet the perceived benefit of discussing sexual health, as well as recognizing a need to discuss HSV-2 with a health-care provider, is a gap in research. The purpose of this interpretive qualitative study was to understand the experiences of African American women who received an asymptomatic HSV-2 diagnosis. Semistructured interviews of seven participants were used to explore the experiences of African American women diagnosed with HSV-2, including barriers and challenges of discussing HSV-2 with health-care providers. Participants highlighted that …

Deep Brain Stimulation: A Treatment Option For Parkinson's, Michael D. Staudt

Conference Presentation Abstracts

No abstract provided.

Hypothalamic Steroid Receptor Coactivator-2 Regulates Adaptations To Fasting And Overnutrition, Yongjie Yang, Yanlin He, Hailan Liu, Wenjun Zhou, Chunmei Wang, Pingwen Xu, Xing Cai, Hesong Liu, Kaifan Yu, Zhou Pei, Ilirjana Hyseni, Makoto Fukuda, Qingchun Tong, Jianming Xu, Zheng Sun, Bert W O'Malley, Yong Xu

Faculty, Staff and Students Publications

The neuroendocrine system coordinates metabolic and behavioral adaptations to fasting, including reducing energy expenditure, promoting counterregulation, and suppressing satiation and anxiety to engage refeeding. Here, we show that steroid receptor coactivator-2 (SRC-2) in pro-opiomelanocortin (POMC) neurons is a key regulator of all these responses to fasting. POMC-specific deletion of SRC-2 enhances the basal excitability of POMC neurons; mutant mice fail to efficiently suppress energy expenditure during food deprivation. SRC-2 deficiency blunts electric responses of POMC neurons to glucose fluctuations, causing impaired counterregulation. When food becomes available, these mutant mice show insufficient refeeding associated with enhanced satiation and discoordination of anxiety …

Élaboration Du Contenu D’Un Site Web Portant Sur L’Incapacité Et Le Retour Au Travail, Christian Larivière, Iuliana Nastasia, Marc Corbière, Manon Truchon, Daniel Côté, Annie Mathieu, Clermont Dionne, Andrea Gragnano, Patrizia Villotti, Alessia Negrini, André Bussières, Marc-Antoine Busque, Martin Lebeau, Marie-France Coutu

Rapports de recherche scientifique

Le corpus de connaissances portant sur l’incapacité au travail est exhaustif et ne cesse de croître. Toutefois, l’appropriation des connaissances par les différents acteurs de la réadaptation et du retour au travail (RT) n’est pas optimale. Une étape essentielle pour faciliter le transfert de ces connaissances est l’accès rapide à de l’information probante et pertinente, centralisée par l’intermédiaire d’un site Web. À notre connaissance, aucune ressource électronique de ce type n’est accessible, sans frais, aux acteurs du Québec. Afin de pallier cette lacune, cette initiative vise à rassembler l’information scientifiquement valide (données probantes) sur l’incapacité au travail et le RT …

Ivermectin Induces Apoptosis Of Esophageal Squamous Cell Carcinoma Via Mitochondrial Pathway, Nana Xu, Mengmeng Lu, Jiaxin Wang, Yujia Li, Xiaotian Yang, Xiajie Wei, Jiaoyang Si, Jingru Han, Xiaojuan Yao, Juanmei Zhang, Junqi Liu, Yanming Li, Hushan Yang, Dengke Bao

Department of Medical Oncology Faculty Papers

Background: Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, the successful treatment remains a mainly clinical challenge, it is imperative to develop successful therapeutic agents.

Methods: The anti-proliferative effect of ivermectin on ESCC is investigated in cell model and in nude mice model. Cell apoptosis was assessed using flow cytometry, TUNEL assay and western blotting. Mitochondrial dysfunction was determined by reactive oxygen species accumulation, mitochondrial membrane potential and ATP levels.

Results: Our results determined that ivermectin significantly inhibited the proliferation of ESCC cells in vitro and in vivo. Furthermore, …

Developing Core-Shell Silver/Polymeric Nano-Composites As Drug Nano-Carriers For Breast Cancer Therapy, Nancy Mohamed El-Baz

Archived Theses and Dissertations

In an attempt to find an effective cancer therapy, nanotherapeutics comes onto the scene as a new therapeutic approach, which is emerging both nanotechnology and biotechnology. Nanotherapeutics offer tremendous advantages over conventional cancer therapy including prolonged drug systemic circulation half-life, targeted drug delivery and nanoparticles-based combination therapy, which result in improving drug pharmacokinetic profile and efficacy/toxicity balance. Recently, ongoing studies regarding cancer therapy are focusing on the anticancer action of various inorganic nanoparticles such as gold (AuNPs) and silver (AgNPs) nanoparticles. In fact, AgNPs have proven a potent anticancer action on different cancer types.

2021-12-06_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173---,00.html.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.

Primary Localized Amyloidosis Of The Ureter With Osseous Metaplasia Presenting As A Suspicious Ureteral Mass, Nada Shaker, Zofia Tynski, Madeline Hudlak, Roy R Brown, Shadi Qasem, Anil Parwani

Pathology and Laboratory Medicine Faculty Publications

Primary amyloidosis of the ureter is a rare disease that is difficult to distinguish from urothelial carcinoma. Only 50 cases of primary ureter amyloidosis have been reported since it was first described in 1937. Of these, only five cases of ureter amyloidosis with osseous metaplasia were reported. In this study, we report the clinical presentation of ureter primary amyloidosis that presented as a mass with osseous metaplasia. The aim of this study is to provide clinicians with knowledge about the clinical/radiologic manifestation that raise the suspicion of amyloidosis, bearing in mind the importance of differentiating it from other "malignant" processes.

2021-12-06_Michiganoverview_Covidschooloutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The School Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102480---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

K-12 School-Related Outbreak Reporting: In accordance with the Council of State and Territorial Epidemiologists' outbreak definition, a K-12 school-associated COVID-19 case (confirmed or probable) is defined as a student, teacher, or staff member physically present in the school setting or participated in a school sanctioned extracurricular activity within 14 days prior to illness onset (or a positive test result) OR …

2021-12-06_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …

2021-12-06_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …