Medicine and Health Sciences Commons^™

Working Happiness And Employee Engagement At Publishing Company., Ltd, Yosaporn Punjamawat, Paul Thisayakorn

Chulalongkorn Medical Journal

Background: The purposes of this research were to study work happiness, employee engagement, and related factors in employees at a medium Publishing Co.,Ltd. Objectives: To study work happiness, employee engagement and related factors that contribute to work happiness of permanent employees at a medium Publishing Co., Ltd. in Bangkok. Methods: Data were collected from 124 employees a medium Publishing Co., Ltd. The questionnaire included general information, work happiness questionnaire, Corporate Engagement Questionnaire and the Patient Health Questionnaire - 9 (PHQ-9). The data were analyzed by Descriptive Statistics, unpaired t - test, One-way ANOVA, Spearman’s correlation co-efficiency and multiple liner regression. …

Correlation Among Pain Catastrophizing, Depressive Symptom, And Activity Of Daily Living In Older Thai Buddhist Monks With Knee Osteoarthritis, Thanakrit Jeamjitvibool, Suparb Aree-Ue, Phichpraorn Youngcharoen, Viroj Kawinwonggowit

Chulalongkorn Medical Journal

Background: Older Thai Buddhist monks are usually accustomed to a unique lifestyle that potentially relates to knee osteoarthritis (OA) such as long-standing kneeling on the hard surface. Understanding the association among pain catastrophizing, depressive symptoms, and activity of daily living (ADL) in this population with knee OA may help reduce the psychosocial problems and promote their sacred activities. Objective: To determine the relationship between pain catastrophizing, depressive symptoms, and ADL in older Thai Buddhist monks with knee OA. Methods: In all, 105 older monks with knee OA were recruited in this study. Data were collected by using a set of …

Prevalence And Associated Factors Of Anxiety And Depression Among Advanced Maternal Age Pregnancy, Kotchakorn Jeeratunyasakul, Chutima Roomruangwong

Chulalongkorn Medical Journal

Background: Advanced maternal age is associated with increased rate of various obstetrics risks. Nowadays, there is increasing prevalence of advanced maternal age in Thailand. However, there is still lack of study in anxiety and depression among this group of pregnant women. Objectives: To examine the prevalence of anxiety and depression as well as associated factors among women with advanced maternal age pregnancy Methods: We recruited 124 pregnant women age  35 years old who were in their third trimester (gestational age  28 weeks) of pregnancy. The subjects were asked to rate: The State-Trait Anxiety Inventory (STAI Form Y) - …

Development Of Vaccines And Antivirals Against Zika Virus, Aryamav Pattnaik

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

The re-emergence of Zika virus (ZIKV), an arbovirus, poses a major global human health concern because of its ability to cause congenital abnormalities and neurological diseases. While many candidate vaccines and antiviral drugs are in the developmental pipeline, none have been approved for use against ZIKV infection. This dissertation describes the characterization of one vaccine and two antiviral drug candidates against ZIKV infection. A bacterial ferritin-based nanoparticle vaccine, termed zDIII-F, is designed to display multiple copies of ZIKV E protein domain III on its surface. These stable nanoparticles are shown to induce robust antibody-mediated protection against lethal ZIKV infection in …

Diabetes Education Empowerment Program (Deep): Evidence-Based Practice Measures For Self-Care Management, Nakeshia Rutledge

Doctor of Nursing Practice Projects

Background: Prediabetes and Type 2 diabetes (T2DM) are major health challenges among the patient population at a family medical clinic in northwest Alabama. Poorly managed T2DM can cause complications which could decrease individuals’ quality of life and lead to mortality.

Purpose: The purpose of this project was to assess the feasibility and efficacy of a self-management intervention aimed at empowering prediabetic and T2DM patients to achieve better diabetes management and glycemic control (hbA1c < 5.7 percent).

Design Methods: A mixed-methods design was utilized with pre/post-questionnaires for analysis of data collected before and after the implementation of an educational intervention on diabetes self-management …

Investigating The Role Of Schizophrenia-Associated Gene Expression In The Developing Human Brain Using Machine Learning, Katie Kelly

Masters

Schizophrenia is a debilitating condition that affects 1% of the population, causes significant hardship and though there are treatments available they are characterised by several limitations. It is a complex mental disorder where some individuals show mild subclinical cognitive symptoms before psychosis onset in adolescence. The treatments available only target a portion of the symptoms and although extensive research has been conducted, a comprehensive understanding of the nature of schizophrenia remains elusive. Unlike other neurodevelopmental disorders, schizophrenia symptoms do not typically present themselves until adolescence. This study aimed to discover gene co-expression networks at multiple developmental stages to identify candidate …

Effects Of Cleaning Agents On The Properties Of Two Different Thermoplastic Retainer Materials, Jennifer Brehove

Master's Theses (2009 -)

Objective: There are several different thermoplastic retainer materials and cleaning methods available to fabricate and clean clear retainers. Some studies have investigated the changes in properties of clear retainers after being exposed to different staining agents, varying levels of mechanical strain, and different cleaning agents. However, there are few studies that compare different thermoplastic materials to each other when being subjected to these different types of stresses. The aim of this study is to evaluate the changes in properties of two commonly used thermoplastic retainer materials, polyethylene terephthalate (PETG) and ethylene/propylene (EP), after exposure to different retainer cleaning agents over …

Comparing Orthodontic Debonding Aerosol Production With Various High-Volume Evacuation Systems, Eric Moe

Master's Theses (2009 -)

Objective: The COVID-19 pandemic has placed a new emphasis on defining aerosol generating procedures and evaluating ways to reduce those aerosols. Both biocontaminants and particulate matter can potentially be transmitted with dental aerosols with negative health effects associated with each, especially aerosols with particulate matter of 2.5 micrometers or less (PM2.5). This study aims to evaluate the PM2.5 aerosol production from orthodontic debonding with a high-speed, air-driven handpiece without water coolant and assess the effectiveness of traditional four-handed high-volume evacuation (HVE) and two commercially available hands-free high-volume evacuation (HFHVE) systems. Methods: Orthodontic debonding was simulated using a dental manikin and …

Bending And Phase Transformation Properties Of A Force Gradient Nickel-Titanium Orthodontic Wire, Brinda Shah

Master's Theses (2009 -)

Objective: Conventional nickel-titanium (NiTi) archwires have widespread application in orthodontics due to their unique properties and ability to move teeth with light, continuous forces, but a shortcoming is that they apply near-uniform force along anterior and posterior teeth. Since the force needed to effectively move teeth is a function of the root surface area and bony support, these archwires cause single-rooted teeth to move more than the multi-rooted molars. With the advent of laser-engineered force gradient NiTi orthodontic archwires, individual forces may be applied to different segments or individual teeth of the arch to maximize tooth movement. The aim of …

Mechanism Of Mechanical Vibration In Enhancing Orthodontic Retention, Brent A. Ito

Master's Theses (2009 -)

Introduction: Low-magnitude, high-frequency (LMHF) mechanical vibration is proven to be anabolic and can increase alveolar bone mass. The objectives of this study were to generate an orthodontic retention cell culture model and investigate the effects of LMHF mechanical vibration on human periodontal ligament fibroblast (HPLF) cells after orthodontic loading (retention) in vitro. Materials and Methods: HPLF cells were seeded at a density of 4x105/well in 6-well Flexcell culture plates (Day 0). On day 3, the cells were mechanically stretched (15% surface extension) for 1 hour to mimic orthodontic loading/tension in vitro. On day 5, the cells were randomly assigned to …

In Vitro Study To Analyze Reverse Torque Values Of Prosthetic Screws With Multiple Loosening/Tightening Preload Cycles, Amira Alhameed

Master's Theses (2009 -)

Purpose: To determine the number of loosening/tightening preload cycles prosthetic retaining screws can withstand before fracture, and to record the reverse torque values on each of the 10 applications of screw tightening and loosening. Materials and methods: The testing assemblies consisted of 30 temporary cylinder/multiunit abutment/internal connection implants, 10 each from Biohorizons, Zimmer Biomet Dental, and Dentsply Sirona Astra; the specimens were inserted into resin blocks. Temporary cylinders were connected to the abutments with new prosthetic screws and torqued to the appropriate preloads. The first tests of repeated tightening/loosening preload cycles were applied using a Digital ® torque gauge instrument …

Hypertrophic Gastric Folds With Hypomagnesemia, Linking The Dots, Mansoor Zafar, Tila Muhammad, Najam-Us-Saher Rizvi, Muhammad Toqeer

Section of Internal Medicine

A Caucasian man in early 80s was seen in Gastroenterology Clinic, following, referral from the Endocrinology Clinic for concerns for CT Abdomen requested for tiredness and weight loss of three kilograms. The patient also had microcytic picture with low MCV and Ferritin and hypomagnesemia. The CT suggested gross circumferential thickening of the wall of stomach with advice for invasive investigations to further characterise the CT findings. The Endoscopy suggested grossly enlarged rugae in the stomach, and enlarged gastric polyps. Patient was assured no new sinister abnormality. Treatment challenges to consider were to stop acid suppression by prescribing Proton Pump Inhibitors …

Correlation Of Serum Calcium With Severity Of Acute Ischaemic Stroke, Ainan Arshad, Saad Bin Zafar Mahmood, Ahmed Ayaz, Mehsa Hashim, Eisha Hanan

Section of Internal Medicine

Stroke results in the death of around 6.5 million people annually with a majority of these occurring in developing countries. Serum calcium has been hypothesised to play a significant role in causing ischaemic stroke. This retrospective observational study was conducted to determine the correlation, if any, between serum calcium and the severity of acute ischaemic stroke in our population. Two hundred and seventy-nine patients admitted with acute ischaemic stroke were enrolled in the study. Of the 279 patients 162 (58%) were male and mean age was 62.4 ± 3.8 years. Characteristics of stroke patients were compared with stroke severity. Mean …

Characterization Of Oral Cavity And Oropharyngeal Cancer In The Texas Rio Grande Valley, Jared A. Sperling, Rachel Giese

MEDI 9331 Scholarly Activities Clinical Years

Cancers of the oral cavity (OC) and oropharynx (OP) account for 3% of cancers diagnosed in the United States each year. A primary cause of death among the Hispanic population in the United States is cancer, accounting for 20% of annual mortality. The Rio Grande Valley (RGV) is a medically-underserved area of South Texas with a large Hispanic population facing health disparities. In this study, we examine the incidence and mortality of OC and OP cancer in the RGV. CDC population-level incidence and mortality rate per 100,000 of OC/OP cancer among patients in the RGV counties of Hidalgo and Cameron …

Investigating The Protective Role Of Irbp Against Oxidative Stress In Diabetic Retinopathy, Matthew N. Parvus, Federico Gonzalez-Fernandez, Reanna Rodriguez, Daniela Gonzalez, Andrew Tsin

MEDI 9331 Scholarly Activities Clinical Years

Introduction:

Diabetic retinopathy is an ocular condition caused by a multitude of factors as a result of elevated blood glucose. One of the primary mechanisms of damage is a result of oxidative stress. It has been found that levels of IRBP in the vitreous are decreased in the setting of diabetic retinopathy, which could be associated with damage from resulting oxidative stress.

Purpose:

This article will address the protective role of IRBP in diabetic retinopathy by discussing the overexpression and under expression of IRBP and its resulting effect on the retina. Increased levels of IRBP in rats with diabetic retinopathy …

Determination Of Freedom-From-Rabies For Small Indian Mongoose Populations In The United States Virgin Islands, 2019–2020, A. Springer Browne, Hannah M. Cranford, Clint N. Morgan, James A. Ellison, Are Berentsen, Nicholas Wiese, Alexandra Medley, John Rossow, Leanne Jankelunas, Alan S. Mckinley, Claudia D. Lombard, Nicole F. Angeli, Thomas Kelley, Jennifer Valiulus, Bethany Bradford, Valicia J. Burke-France, Cosme J. Harrison, Irene Guendel, Marissa Taylor, Gerard L. Blanchard, Jeffrey B. Doty, David J. Worthington, David Horner, Keith R. Garcia, Joseph Roth, Brett R. Ellis, Kristine M. Bisgard, Ryan Wallace, Esther M. Ellis

United States Department of Agriculture Wildlife Services: Staff Publications

Mongooses, a nonnative species, are a known reservoir of rabies virus in the Caribbean region. A cross-sectional study of mongooses at 41 field sites on the US Virgin Islands of St. Croix, St. John, and St. Thomas captured 312 mongooses (32% capture rate). We determined the absence of rabies virus by antigen testing and rabies virus exposure by antibody testing in mongoose populations on all three islands. USVI is the first Caribbean state to determine freedom-from-rabies for its mongoose populations with a scientifically-led robust cross-sectional study. Ongoing surveillance activities will determine if other domestic and wildlife populations in USVI are …

Testing A Bite-Shortened Hook To Minimize Fish Handling In A Recreational Fishery, Holden E. Harris, Brian K. Whalen, Andrew G. Gude, Michael S. Allen

United States Department of Agriculture Wildlife Services: Staff Publications

Discard mortality can make fishing unsustainable, even in catch-and-release or highly regulated fisheries. However, fishing practices and gears that minimize hook injury, handling, and air exposure can considerably improve fitness and survival in released fish. This study tested whether modified hooks could allow anglers to successfully land and then release fish in the water and without handling. Standard, barbless, and bite-shortened hooks were used to catch Spotted Seatrout Cynoscion nebulosus (n > 75 per hook type), and logistic models were used to assess the differences in landing success and hook self-release success by hook type and categorical fish size. Average landing …

The Assessment Of Clinical Reasoning In Preceptors Across The Athletic Training Profession, Gary Wayne Cohen Jr.

Health Services Research Dissertations

Clinical reasoning (CR) is defined as a complex multi-factorial metacognitive process for diagnosis formulation. Clinical reasoning begins as a student and develops over a career. Students are typically taught an analytical approach defined as hypothetico-deductive reasoning (HDR). Expert clinicians use a non-analytical approach defined as the Knowledge Based Model (KBM) of CR. It is accepted that clinicians use the KBM with cases that they have more experience to streamline the evaluation process. Unfortunately, because of the nuance of CR there have been limited investigations within athletic training to evaluate CR outside of the student population.

The overarching purpose of this …

Examining The Use Of Immersive Clinical Experiences In Athletic Training Education, Bailey Christine Jones

Health Services Research Dissertations

Clinical experiences are an essential aspect of athletic training education that offer students opportunities to practice their skills and engage in a variety of settings. The Commission on Accreditation of Athletic Training Education (CAATE) sets accreditation standards for athletic training programs to meet, including clinical education standards. In fall 2020, new standards took effect that include a few additions to the standards surrounding clinical education; these additions require programs to afford students opportunities to engage in immersive clinical experiences (ICEs), implement behaviors associated with core competencies, and identify strategies that account for patients’ social determinants of health. Educators believe ICEs …

The Politics Of Medicine: Power, Actors, And Ideas In The Making Of Health, Claire Wulf Winiarek

Graduate Program in International Studies Theses & Dissertations

The practice of medicine has become the prescribing of medicine. Reflecting a construct of health defined by Rationalism, individualism, and biomedical science, medicines (pharmaceuticals) are politically constructed to be the first – and sometimes only prescribed – line of defense against illness and disease. Pharmaceuticals also represent a highly desirable, ‘recession-proof’ component of many Nation-states’ (states’) export strategies, helping advanced economies, in particular, to maintain favorable trade balances and economic growth amidst the headwinds of deindustrialization.

Higher use and the overreliance on pharmaceuticals promote an outsized role for certain actors and ideas in the making of global health, referring to …

Intermittent Hypoxia And Effects On Early Learning/Memory: Exploring The Hippocampal Cellular Effects Of Pediatric Obstructive Sleep Apnea, Arvind Chandrakantan, Adam C Adler, Mehmet Tohsun, Farrah Kheradamand, Russell S Ray, Steven Roth

Faculty, Staff and Students Publications

This review provides an update on the neurocognitive phenotype of pediatric obstructive sleep apnea (OSA). Pediatric OSA is associated with neurocognitive deficits involving memory, learning, and executive functioning. Adenotonsillectomy (AT) is presently accepted as the first-line surgical treatment for pediatric OSA, but the executive function deficits do not resolve postsurgery, and the timeline for recovery remains unknown. This finding suggests that pediatric OSA potentially causes irreversible damage to multiple areas of the brain. The focus of this review is the hippocampus, 1 of the 2 major sites of postnatal neurogenesis, where new neurons are formed and integrated into existing circuitry …

The Why, Where, And How Clinical Reasoning Model For The Evaluation And Treatment Of Patients With Low Back Pain, Sean P. Riley, Brian T. Swanson, Joshua Cleland

Physical Therapy Faculty Publications

Objective

The objective of this theoretical clinical reasoning model is to provide a framework to help clinicians integrate linear and non-linear clinical reasoning approaches to minimize clinical reasoning errors related to logically fallacious thinking and cognitive biases.

Methods

This masterclass proposes a hypothesis-driven and probabilistic approach that uses clinical reasoning for managing LBP that seeks to eliminate the challenges related to using any single diagnostic paradigm.

Conclusions

This model integrates the why (mechanism of primary symptoms), where (location of the primary driver of symptoms), and how (impact of mechanical input and how it may or may not modulate the patient's …

Administering A Combination Of Online Dietary Assessment Tools, The Automated Self-Administered 24-Hour Dietary Assessment Tool, And Diet History Questionnaire Ii, In A Cohort Of Adults In Alberta's Tomorrow Project, Nathan M. Solbak, Paula J. Robson, Geraldine Lo Siou, Ala Al Rajabi, Seol Paek, Jennifer E. Vena, Sharon I. Kirkpatrick

All Works

Background: Evidence suggests that combining tools that gather short- and long-term dietary data may be the optimal approach for the assessment of diet–disease associations in epidemiologic studies. Online technology can reduce the associated burdens for researchers and participants, but feasibility must be demonstrated in real-world settings before wide-scale implementation. Objective: The objective of this study was to determine the feasibility and acceptability of combining web-based tools (the Automated Self-Administered 24-hour Dietary Assessment Tool [ASA24-2016] and the past-year Diet History Questionnaire II [DHQ-II]) in a subset of participants in Alberta's Tomorrow Project, a prospective cohort. Design: For this feasibility study, invitations …

Tracetogether And Safeentry Were Never Foolproof In Averting Recent Fishery Port And Ktv Clusters, Mark Findlay

Research Collection Yong Pung How School Of Law

Don’t blame the technology. COVID-19 control technology depends on the cooperation of people to be fully effective, says SMU Professor Mark Findlay. Singapore has one of the best subscribed COVID-19 tracing, tracking and safe entry apps worldwide. Then how is it that we are back to Phase 2 (Heightened Alert)? It would be tempting but wrong to blame the technology as being insufficiently intrusive or robust. A look at the recent outbreak suggests we should avoid an over-reliance on tech solutions when incompatible human behaviours are at work.

Efficiency Of Prolonged Prone Positioning For Mechanically Ventilated Patients Infected With Covid-19, Elizabeth M. Parker, Edward A. Bittner, Lorenzo Berra, Richard M. Pino

School of Medicine Faculty Publications

Hypoxemia of the acute respiratory distress syndrome can be reduced by turning patients prone. Prone positioning (PP) is labor intensive, risks unplanned tracheal extubation, and can result in facial tissue injury. We retrospectively examined prolonged, repeated, and early versus later PP for 20 patients with COVID-19 respiratory failure. Blood gases and ventilator settings were collected before PP, at 1, 7, 12, 24, 32, and 39 h after PP, and 7 h after completion of PP. Analysis of variance was used for comparisons with baseline values at supine positions before turning prone. PP for >39 h maintained PaO2/FiO2 (P/F) ratios when …

Urban And Rural Disparities In A Wechat-Based Smoking Cessation Intervention Among Chinese Smokers, Ting Luo, Mirandy Li, Donna Williams, Jackson Fritz, Stephen W. Phillippi, Qingzhao Yu, Stephen Kantrow, Liwei Chen, Yongchun Chen, Kaylin Beiter, Tung-Sung Tseng

School of Public Health Faculty Publications

Introduction: Tobacco use, which is directly responsible for 10% of total deaths per year globally, remains consistently high, with approximately 20% of the population reporting regular consumption globally. Moreover, health disparities regarding tobacco consumption and smoking cessation are growing between rural and urban populations worldwide. Social media interventions for tobacco cessation may effectively reach both groups. The objective of this study was to evaluate the efficacy of a WeChat-delivered smoking cessation intervention among rural and urban Chinese smokers, and to assess moderating variables that may contribute to differential intervention efficacy. Methods: WeChat was used to recruit smokers into this intervention …

Neuromuscular Function In Achilles Tendinopathy, Lauren K. Sara

Dissertations (1934 -)

Midportion Achilles tendinopathy (AT) is a chronic, painful condition of the long tendon that attaches the triceps surae muscle group (the soleus, medial and lateral gastrocnemius muscles), which are the primary plantar flexor muscles, to the calcaneus bone. There is incomplete understanding of the underlying pathophysiology, pain, and role of plantar flexor function (strength and fatigability) in functional impairment in AT. Deficits in plantar flexor muscle function are assumed, but evidence is sparce and inconclusive. There is no understanding of whether people with AT have deficits in neural drive to the plantar flexor muscles or altered contractile function, or the …

Taste Learning In Insular Cortex: Plasticity Is Influenced By Experience Type, Stephanie Marie Staszko

Theses and Dissertations (ETD)

The gustatory cortex (GC) has long been studied as the main cortical area encoding taste stimuli and likely integrates sensory, visceral, and emotional information to guide taste-related behaviors. However, our understanding of cortical taste coding on a single-cell level has only become clear in recent years. The anatomical location of GC on the lateral and ventral surface of the brain makes it difficult to target with traditional imaging methods. Thus, much of what we know about cortical taste coding and cortical taste plasticity has been derived either from multiunit electrode recordings or anesthetized imaging experiments, techniques which lack the ability …

A Retrospective Cross-Sectional Study Of The Effect Of Liposomal Bupivacaine On Postoperative Opioid Prescribing After Third Molar Extraction, Stuart E. Lieblich, Dale Misiek, John Olczak, Heidi Fleck, Fanta Waterman

School of Dentistry Faculty Publications

Purpose: Reducing opioid prescriptions after third molar extraction may decrease the risk of opioid dependence. This study compared prescribed morphine milligram equivalents (MMEs) in patients undergoing mandibular third molar removal with and without use of liposomal bupivacaine (LB). Methods: This retrospective cross-sectional study included deidentified data from electronic medical records of patients who underwent extraction of ≥1 partial bony—or full bony—impacted mandibular third molar at 2 oral surgery centers in the United States in 2012 or 2018. The primary predictor variable was use of LB 133 mg. The primary outcome variable was total prescribed opioids in MMEs. The secondary outcome …

When We Know Better, We Do Better: Maintaining And Retrieving Advance Directive Documents In The Electronic Health Record, Linda Caurdy-Bess, Sara Damiano, Amy Fresch, Marilyn Begle, Srikala Yedavally-Yellayi, Hany A. Eraqi, Ali H. Mahmood

Articles

LEARNING OBJECTIVES: 1. Define and understand the value of an advance care planning system approach at a large health system. 2. Learn how to evaluate the rate and quality of advance directive documents uploaded in the EHR. 3. Gain practical skills to leverage stakeholder engagement and resource development to enhance an advanced care planning system approach.