Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Public Health (4751)
- Medical Specialties (4711)
- Nursing (2494)
- Life Sciences (2385)
- Medical Sciences (2277)
-
- Social and Behavioral Sciences (2107)
- Diseases (1767)
- Education (1474)
- Medical Education (1162)
- Rehabilitation and Therapy (1061)
- Mental and Social Health (1003)
- Physical Sciences and Mathematics (830)
- Pharmacy and Pharmaceutical Sciences (802)
- Pediatrics (742)
- Sports Sciences (671)
- Arts and Humanities (659)
- Public Health Education and Promotion (612)
- Dentistry (561)
- Veterinary Medicine (556)
- Psychology (547)
- Epidemiology (540)
- Higher Education (515)
- Psychiatry and Psychology (513)
- Oncology (512)
- Occupational Therapy (511)
- Health and Medical Administration (491)
- Community Health and Preventive Medicine (486)
- Business (443)
- Engineering (433)
- Institution
-
- Western Michigan University (1248)
- Thomas Jefferson University (975)
- Aga Khan University (808)
- The Texas Medical Center Library (767)
- University of Kentucky (666)
-
- TÜBİTAK (534)
- Chulalongkorn University (504)
- Walden University (482)
- Washington University School of Medicine (389)
- Edith Cowan University (387)
- University of South Carolina (343)
- Children's Mercy Kansas City (330)
- Universitas Indonesia (327)
- University of Nebraska Medical Center (301)
- Manipal Academy of Higher Education (293)
- Western Kentucky University (289)
- University of Texas Rio Grande Valley (286)
- University of Nebraska - Lincoln (282)
- University of Nevada, Las Vegas (282)
- Himmelfarb Health Sciences Library, The George Washington University (258)
- Georgia Southern University (244)
- Lehigh Valley Health Network (243)
- Nova Southeastern University (240)
- City University of New York (CUNY) (235)
- Western University (205)
- Wayne State University (204)
- Wright State University (200)
- University of Mississippi (196)
- University of Alabama at Birmingham (190)
- Chapman University (185)
- Keyword
-
- COVID-19 (2007)
- Michigan (1055)
- Humans (944)
- Female (398)
- Male (367)
-
- COVID-19 cases (330)
- SARS-CoV-2 (264)
- Animals (233)
- Mental health (233)
- Adult (213)
- Hospital data (198)
- Depression (192)
- Obesity (187)
- Symptoms (187)
- Aged (178)
- Middle Aged (177)
- Syndromic surveillance (177)
- Nursing (175)
- Epidemiology (172)
- Pandemic (171)
- Coronavirus (167)
- Public health (166)
- Map (155)
- Mice (154)
- Children (152)
- Education (151)
- Occupational therapy (146)
- Pregnancy (142)
- Child (136)
- Georgia Southern University (136)
- Publication
-
- Walden Dissertations and Doctoral Studies (465)
- Turkish Journal of Medical Sciences (416)
- 2020-Current year OA Pubs (383)
- Research outputs 2014 to 2021 (365)
- Theses and Dissertations (348)
-
- Chulalongkorn University Theses and Dissertations (Chula ETD) (327)
- Faculty, Staff and Students Publications (312)
- Faculty Publications (243)
- International Journal of Exercise Science: Conference Proceedings (226)
- Cumulative Michigan COVID-19 Data (224)
- Faculty, Staff and Student Publications (224)
- Daily Michigan COVID-19 Update (222)
- Michigan COVID-19 Hospital Data (199)
- Doctor of Nursing Practice Projects (185)
- Michigan COVID-19 Syndromic Surveillance System Data (177)
- Phase 1 (176)
- Electronic Theses and Dissertations (170)
- School of Medicine Publications (165)
- Faculty Research 2021 (155)
- Publications and Research (145)
- Conference Presentation Abstracts (140)
- Kasturba Medical College, Mangalore Theses and Dissertations (136)
- United States Department of Agriculture Wildlife Services: Staff Publications (136)
- All ETDs from UAB (121)
- Dissertations (121)
- Manuscripts, Articles, Book Chapters and Other Papers (118)
- Turkish Journal of Veterinary & Animal Sciences (118)
- Honors Theses (113)
- Posters (111)
- Michigan COVID-19 Outbreak Reports (103)
- Publication Type
Articles 601 - 630 of 21389
Full-Text Articles in Medicine and Health Sciences
Coaching In Context: Implications For Practice & Parent Perspectives, Rachel Y. Kim, Otd, Otr/L, N. Gerhardt, Ms, Otr/L, Cbis, Bernadette Alpajora, Otd, Otr/L, Mj Mulcahey, Phd, Otr/L, Fasia, Clcp
Coaching In Context: Implications For Practice & Parent Perspectives, Rachel Y. Kim, Otd, Otr/L, N. Gerhardt, Ms, Otr/L, Cbis, Bernadette Alpajora, Otd, Otr/L, Mj Mulcahey, Phd, Otr/L, Fasia, Clcp
Department of Occupational Therapy Posters and Presentations
Introduction
- Informal care partners experience high levels of guilt, stress, anxiety, depression, and overall decreased health and wellness1-3.
- There is a gap in accessibility of services for informal care partners of individuals with chronic conditions4.
- Care partners of individuals with chronic conditions need long-term support and skill-building for the health & well-being of their care recipient and themselves5.
Coaching in Context
- Coaching in Context (CinC) (Figure 1) is a client-driven approach that leverages client’s strengths and addresses challenges through problem-solving skills.
- Coaches connect with clients to build a trusting relationship. The coach uses skillful questioning to enable the client to …
From Burnout To Occupational Depression: Recent Developments In Research On Job-Related Distress And Occupational Health, Irvin Sam Schonfeld, Renzo Bianchi
From Burnout To Occupational Depression: Recent Developments In Research On Job-Related Distress And Occupational Health, Irvin Sam Schonfeld, Renzo Bianchi
Publications and Research
Job-related distress has been a focal concern in occupational health science. Job-related distress has a well-documented health-damaging and life-threatening character, not to mention its economic cost. In this article, we review recent developments in research on job-related distress and examine ongoing changes in how job-related distress is conceptualized and assessed. By adopting an approach that is theoretically, empirically, and clinically informed, we demonstrate how the construct of burnout and its measures, long favored in research on job-related distress, have proved to be problematic. We underline a new recommendation for addressing job-related distress within the long-established framework of depression research. In …
Increasing Healthcare Providers' Intent To Utilize Alternative And Complementary Pain Management With Their Patients, Holli Boyles
Increasing Healthcare Providers' Intent To Utilize Alternative And Complementary Pain Management With Their Patients, Holli Boyles
Doctor of Nursing Practice Scholarly Project
The purpose of this scholarly project is to increase the willingness of healthcare providers to introduce alternative and complementary pain management to their patients. Two patient video tools were constructed and offered to healthcare providers to evaluate and potentially utilize the final products in their practice. One tool introduced music therapy, the other mindful meditation, along with resources for patients to investigate and learn from on their own. A total of seven healthcare providers responded to the project with a commitment to potentially utilize the final video and provided their feedback on the video tools. No changes were made to …
Program Development And Evaluation Of A Diabetes Self-Management Education And Support Toolkit On An E-Learning Platform For Young Adults Living With Type 2 Diabetes, Marlene Eicher
Doctor of Nursing Practice Scholarly Project
The purpose of this project was to develop and evaluate the effectiveness of a diabetes education toolkit on an e-learning platform for improving individual self-management and medication knowledge to promote healthy lifestyle behaviors for young adults living with type 2 diabetes mellitus (T2DM).
A descriptive, quasi-experimental design with one-group pretest-posttest was used. Participants were recruited from an independently owned medical clinic. The participants were English-speaking young adults, between ages 18 to 39 with a diagnosis of prediabetes or T2DM. The intervention was a DSMES toolkit with twelve e-learning modules that participants completed over a three-month period. Data collected was age …
Navigating The Impact Of Covid-19 On Small Commercial Businesses And Insurance Companies, And A Call To Action For Future Communicable Disease Outbreaks, Natalie Peña
Honors Program Theses and Research Projects
The short-term and long-term effects of Covid-19 have caused many small commercial businesses to face financial hardships, loss of employees, and even closures for entities that were already experiencing low profit margins. Distraught with their businesses suffering, owners turned to their primary insurance companies to receive compensation through their business interruption policies. However, most insureds were upset when they discovered that their insurance plans did not include communicable diseases and pandemics as a covered peril. This led to many small businesses battling these issues in the courts and fighting for insurance companies to provide financial assistance to them during this …
2021-12-10_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services
2021-12-10_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services
Cumulative Michigan COVID-19 Data
The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.
The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …
Spinal Cord Injury-Movement Index (Sci-Mi) Fine Motor Item Pool: Development And Preliminary Validation, Rachel Y. Kim, Otd, Nicole Gerhardt, Ms, Otr/L, Mj Mulcahey, Phd, Otr/L, Fasia
Spinal Cord Injury-Movement Index (Sci-Mi) Fine Motor Item Pool: Development And Preliminary Validation, Rachel Y. Kim, Otd, Nicole Gerhardt, Ms, Otr/L, Mj Mulcahey, Phd, Otr/L, Fasia
Department of Occupational Therapy Posters and Presentations
Purpose: Describe the conceptual framework and preliminary results from pretesting for content validation of the Fine Motor Item Pool of the SCI-MI.
Exploring A Piloted Occupational Therapy Toolkit For Military Children And Youth In Addressing Occupational Performance, Mirely Murcio, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert
Exploring A Piloted Occupational Therapy Toolkit For Military Children And Youth In Addressing Occupational Performance, Mirely Murcio, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert
Fall 2021 Virtual OTD Capstone Symposium
In the United States (U.S.) there are more family members than military personal in the Department of Defense force with 62.8% of the 2,619,788 family members are children. Research indicates that children of active-duty service members experience unique challenges compared to same age peers due to military life and culture that create occupational disruptions. Research has shown that evidenced based interventions and assessments are needed to support the resilience of military connected children and youth to support their overall health and mental health resulting from the effects of parental deployment and military stressors.
The problem is that despite growing literature …
A Literature Review Of Mild Traumatic Brain Injury Research, Brindlea Peterson
A Literature Review Of Mild Traumatic Brain Injury Research, Brindlea Peterson
Honors Theses
Mild traumatic brain injuries (mTBI) are a type of traumatic brain injury (TBI) usually sustained from an injury to the head and are hard to diagnose due to the lack of physical evidence seen in diagnostic radiology. The estimated worldwide rate of incidence each year is 42 million, making mTBIs rather common. In the US armed forces, that rate of incidence is even higher due to the dangerous nature of the work being done. Many complications can come from not properly addressing an mTBI after it happens which makes being able to determine an appropriate return-to-play or return-to-duty time very …
Healthcare Access Barriers And Proposed Solutions For Limited English-Proficient (Lep) Latinx Patients In Southwest Michigan, Carmen Vinkemulder
Healthcare Access Barriers And Proposed Solutions For Limited English-Proficient (Lep) Latinx Patients In Southwest Michigan, Carmen Vinkemulder
Honors Theses
This research study explores the circumstances and experiences of LatinX patients with limited English proficiency (LEP) when seeking treatment in the healthcare system of Southwest Michigan, in addition to proposing solutions to better facilitate this population’s access. The terminology used in this research, LatinX, is an American English neologism used as a genderinclusive term used interchangeably with Latino/a and/or Hispanic. This research provides an overview of the current socio-political legislature and climate of the American healthcare system as it pertains to the LatinX population to spread awareness and identify the barriers existing in our current healthcare model. This study will …
Pragmatic Deficits In Attention-Deficit/Hyperactivity Disorder: Systematic Review And Meta-Analysis, Paige Kessler
Pragmatic Deficits In Attention-Deficit/Hyperactivity Disorder: Systematic Review And Meta-Analysis, Paige Kessler
Honors Theses
Background: Most studies have found pragmatic language skills to be poorer in attention-deficit/hyperactivity disorder (ADHD) populations, but there is no conclusive evidence.
Aim: Our aim was to conduct a meta-analysis of pragmatic language abilities in ADHD populations to more definitively demonstrate the extent of pragmatic language deficits in these populations as compared to typically developing (TD) populations.
Methods and procedures: Journal articles were identified using the search terms ((attention deficit) OR (adhd)) AND (pragmatics). Identified studies were screened and reviewed for inclusion criteria, descriptive information, and outcome variables. A meta-analysis was conducted, and individual effect sizes and overall effect size …
The Efficacy Of The Low-Fodmap Diet To Alleviate Symptoms Of Irritable Bowel Syndrome In Adults: A Systematic Review, Jacqueline Nicole Rustom
The Efficacy Of The Low-Fodmap Diet To Alleviate Symptoms Of Irritable Bowel Syndrome In Adults: A Systematic Review, Jacqueline Nicole Rustom
Theses and Dissertations
Irritable bowel syndrome (IBS) is a functional bowel disorder with 6.5% worldwide prevalence that causes gas production, abdominal distension, and abdominal pain or discomfort. This systematic review describes efficacy of the Low-Fermentable Oligosaccharides, Disaccharides, Monosaccharides And Polyols (FODMAP) diet (Low-FODMAP diet or LFD) to alleviate IBS symptoms using the PRISMA guidelines. Nine randomized controlled trials (RCT) and one non-RCT consecutive controlled study published between 2015 to 2019 were identified using PubMed and CENTRAL. Included studies involved adult IBS participants with symptoms of abdominal pain, constipation, and/or diarrhea. A total of 530 participants completed the interventions from the 10 studies included …
Macronutrient Intake: A Multi-Sport Study Of Female Division I Collegiate Athletes, Ffion Price
Macronutrient Intake: A Multi-Sport Study Of Female Division I Collegiate Athletes, Ffion Price
Theses and Dissertations
Background: Macronutrients play a critical role within collegiate athletes’ performance and health, with carbohydrates providing most of the energy needs for most athletes. There is little research examining the macronutrient intake of healthy collegiate female athletes across sports. The aim of the present study was to compare macronutrient intakes of female collegiate athletes within different sports and compare their intakes to recommendations. Methods: An observational study was conducted to determine whether a sample of female collegiate athletes (n=26) consumed the IOC nutritional recommendations. Sports included within the study were soccer, basketball, volleyball, and cross-country. Athletes were asked to complete a …
New Orleans During A Pandemic: Engaging African American Community Stakeholders On Covid-19 Information, Prevention, Testing And Vaccination, Anthony Thompson
New Orleans During A Pandemic: Engaging African American Community Stakeholders On Covid-19 Information, Prevention, Testing And Vaccination, Anthony Thompson
XULAneXUS
This case study examines how the Louisiana Community Engagement Alliance Against COVID-19 Disparities (LA-CEAL) worked to engage African American residents in New Orleans during the COVID-19 pandemic. Drawing on research interviews with Black physicians, pharmacists, and community health providers, along with field notes collected during 12 months of project assistance, the study addresses four research questions concerning African American hesitancy toward COVID-19 treatment and vaccination, strategies for community engagement, clinical trial recruitment, and inclusive research practices during a pandemic. Findings indicate that vaccine hesitancy and research mistrust among Black New Orleanians are rooted in a long history of scientific racism …
Pharmacist Avoidance Or Reductions In Medical Costs In Critically Ill Adults: Pharm-Crit Study, Megan A. Rech, Payal K. Gurnani, William J. Peppard, Keaton S. Smetana, Megan A. Van Berkel, Drayton A. Hammond, Alexander H. Flannery
Pharmacist Avoidance Or Reductions In Medical Costs In Critically Ill Adults: Pharm-Crit Study, Megan A. Rech, Payal K. Gurnani, William J. Peppard, Keaton S. Smetana, Megan A. Van Berkel, Drayton A. Hammond, Alexander H. Flannery
Pharmacy Practice and Science Faculty Publications
OBJECTIVES: To comprehensively classify interventions performed by ICU clinical pharmacists and quantify cost avoidance generated through their accepted interventions.
DESIGN: A multicenter, prospective, observational study was performed between August 2018 and January 2019.
SETTING: Community hospitals and academic medical centers in the United States.
PARTICIPANTS: ICU clinical pharmacists.
INTERVENTIONS: Recommendations classified into one of 38 intervention categories (divided into six unique sections) associated with cost avoidance.
MEASUREMENTS AND MAIN RESULTS: Two-hundred fifteen ICU pharmacists at 85 centers performed 55,926 interventions during 3,148 shifts that were accepted on 27,681 adult patient days and generated $23,404,089 of cost avoidance. The quantity of …
College Of Public Heath News, Georgia Southern University
College Of Public Heath News, Georgia Southern University
College of Public Health: News & Publications
- Georgia Southern Establishes New Institute to Better Address Challenges Related to Water and Human Interactions
Case Report: Neurologic Presentation Of West Nile Virus: Difficult Diagnosis, Eron G. Manusov, Amalia Mora Campuzano, Omar Ahmed, Samantha Macias, Carolina Gomez De Ziegler, Gerardo Munoz Monaco
Case Report: Neurologic Presentation Of West Nile Virus: Difficult Diagnosis, Eron G. Manusov, Amalia Mora Campuzano, Omar Ahmed, Samantha Macias, Carolina Gomez De Ziegler, Gerardo Munoz Monaco
School of Medicine Publications
West Nile virus infections have surged across the globe. South Texas, located on the path of bird migration, with Culex quinquefasciatus and other Culex species, and biotic primers that predispose the area to epidemics (floods, amplifying hosts, and lack of mosquito control and prevention) remains a highly endemic area for arbovirus spread. West Nile virus infection ranges from mild febrile illness to severe central nervous system involvement. The purpose of this report is to highlight complex presentations of WNV and how confounding presenting symptoms delay diagnosis. The secondary goal is to describe how pandemics, such as SARS-CoV-2, can overwhelm the …
Occupation Based Program For African American Crossover Youth Aging Out Of Foster Care, Sadé Barnswell, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert
Occupation Based Program For African American Crossover Youth Aging Out Of Foster Care, Sadé Barnswell, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert
Fall 2021 Virtual OTD Capstone Symposium
Unique challenges and differences surround the population of African American crossover youth and how they successfully transition into adulthood once aged out of foster care as compared to same-aged peers (Kim et al., 2019). The problem is that African American crossover youth aging out of the foster care system, are not receiving occupation-based transitional services focusing on IADLs required for adulthood independence resulting in increased prevalence of homelessness (Armstrong-Heimsoth et al., 2020; Flores et al., 2018; Kelly, 2020; Paul-Ward & Lambdin-Pattavina, 2016; Pérez et al., 2019). The purpose of this program development type project is to develop and implement an …
Exploration Of Occupational Therapy’S Role Within The Lgbtq+ Population, Crystal Garcia, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert
Exploration Of Occupational Therapy’S Role Within The Lgbtq+ Population, Crystal Garcia, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert
Fall 2021 Virtual OTD Capstone Symposium
There are an estimated 11 million individuals who identify as LGBTQ+ in the United States (Rosendale et al., 2019). With this number steadily increasing, it is important that occupational therapists continue to become culturally competent and educated on different strategies to transform the way individuals who identify as LGBTQ+ are given and receive treatment. The problem is that there is a gap in the literature supporting occupational therapist cultural competence to integrate occupational roles of the LGBTQ+ population into their evaluation and intervention. Without culturally competent educational opportunities, the health care system is inadequately prepared to provide responsive health care …
Descriptive Study Of A Healthy Weight Management Program For Overweight Or Obese Children And Youth, Chad Roberts, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert
Descriptive Study Of A Healthy Weight Management Program For Overweight Or Obese Children And Youth, Chad Roberts, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert
Fall 2021 Virtual OTD Capstone Symposium
The rise in obesity among children and youth in the last 20 years is a public health concern. The prevalence of childhood obesity has multiplied worldwide in the last four decades (“The Heavy Burden of Obesity and the Economics of Prevention,” 2019). Obesity is a complex chronic disease in which abnormal or excessive accumulation of body fat impairs health (Wharton et al., 2020). Childhood obesity can profoundly affect children's physical health, social and emotional well-being, and self-esteem (Rankin et al., 2016 & Purnell et al., 2018). The problem is a lack of an occupation-based evaluation tool utilized to link occupational …
The Relationship Between Collective Nursing Knowledge And Nurse Turnover: An Application Of Nursing Intellectual Capital Theory, Pamela Russman-Chambers
The Relationship Between Collective Nursing Knowledge And Nurse Turnover: An Application Of Nursing Intellectual Capital Theory, Pamela Russman-Chambers
Doctorate of Nursing Science Dissertations
The value of a healthcare organization is vested in the expertise, intellect, and wisdom of employees. Nursing knowledge resides both within the individual nurse and the collective knowledge embedded in organizational structures and practice environments. Healthcare organizations rely on their ability to utilize this knowledge to deliver high-quality care to patients. Hospitals wanting to gain a competitive advantage and achieve financial stability must be adept at acquiring, cultivating, and using the nursing knowledge stocks of the organization. When this knowledge can be utilized to mitigate healthcare issues and improve patients' health, this collective knowledge or intellectual capital is often the …
Internalized Stigma, Depressive Symptoms, And The Modifying Role Of Antiretroviral Therapy: A Cohort Study In Rural Uganda, Lisa M. Bebell, Annet Kembabazi, Nicholas Musinguzi, Jeffrey N. Martin, Peter W. Hunt, Yap Boum Ii, Kelli N. O'Laughlin, Conrad Muzoora, Jessica E. Haberer, Mwebesa Bosco Bwana, David R. Bangsberg, Mark J. Siedner, Alexander C. Tsai
Internalized Stigma, Depressive Symptoms, And The Modifying Role Of Antiretroviral Therapy: A Cohort Study In Rural Uganda, Lisa M. Bebell, Annet Kembabazi, Nicholas Musinguzi, Jeffrey N. Martin, Peter W. Hunt, Yap Boum Ii, Kelli N. O'Laughlin, Conrad Muzoora, Jessica E. Haberer, Mwebesa Bosco Bwana, David R. Bangsberg, Mark J. Siedner, Alexander C. Tsai
OHSU-PSU School of Public Health Faculty Publications and Presentations
Depression affects over 40% of people with HIV (PHIV) in low- and middle-income countries, and over half of PHIV report HIV-related internalized stigma. However, few longitudinal studies of PHIV have examined the relationship between HIV-related stigma and depression. Data were analyzed from the 2007-15 Uganda AIDS Rural Treatment Outcomes (UARTO) Study, a cohort of 454 antiretroviral therapy (ART)-naïve PHIV (68% women) starting ART. Our primary outcome was depression symptom severity over the first two years of ART, measured using a locally adapted version of the Hopkins Symptom Checklist; our primary exposure was the 6-item Internalized AIDS-Related Stigma Scale. Both scores …
Identifying And Evaluating Pain Management In Hospitalized Older Adults With Hip Fractures: An Integrative Review, Monique Guinocor
Identifying And Evaluating Pain Management In Hospitalized Older Adults With Hip Fractures: An Integrative Review, Monique Guinocor
Master of Science in Nursing Final Projects
Hip fractures are known to have the highest health morbidity and mortality, especially in the aging population. Having a hip fracture comes with insurmountable pain. Older adults experiences pain differently from other populations due to physiological changes, but this population experiences an undertreatment and mistreatment for pain, resulting in negative outcomes. Current methods for pain control include pharmacologic and nonpharmacologic interventions. Exploring different interventions for pain management is necessary so providers can implement methods that are effective in pain relief without inducing complications. The aim of this integrative review is to identify current pain management interventions and determine their effectiveness …
Basis For Changes In The Disease Burden Estimates Related To Vitamin A And Zinc Deficiencies In The 2017 And 2019 Global Burden Of Disease Studies, Sonja Y. Hess, Alexander C. Mclain, Haley Lescinsky, Kenneth H. Brown, Ashkan Afshin, Reed Atkin, Saskia Jm Osendarp
Basis For Changes In The Disease Burden Estimates Related To Vitamin A And Zinc Deficiencies In The 2017 And 2019 Global Burden Of Disease Studies, Sonja Y. Hess, Alexander C. Mclain, Haley Lescinsky, Kenneth H. Brown, Ashkan Afshin, Reed Atkin, Saskia Jm Osendarp
Faculty Publications
Background:
The Global Burden of Disease (GBD) Study provides estimates of death and disability from eighty-seven risk factors, including some micronutrient deficiencies. Objectives:
To review methodological changes that led to large differences in the disease burden estimates for vitamin A and Zn deficiencies between the GBD 2017 and 2019 Studies. Methods:
GBD publications were reviewed; additional information was provided by GBD researchers. Results:
Vitamin A deficiency prevalence is based on plasma retinol concentration, whereas the estimate for Zn deficiency prevalence uses dietary adequacy as a proxy. The estimated global prevalence of vitamin A deficiency for children aged 1–4 years in …
Serving Our Students: Evidence-Based Sex Education Policies And Practices Needed In Ohio, Lily Mckenzie Rosenberg
Serving Our Students: Evidence-Based Sex Education Policies And Practices Needed In Ohio, Lily Mckenzie Rosenberg
Honors Projects
Ohio has very minimal state-wide sex education laws, requiring only venereal disease education that has many similarities with abstinence-only education. Abstinence-only education has been shown to be ineffective in delaying first sex and lowering teen STDs, pregnancy, and birth rates. When students receive ineffective (or no) sex education it can impact them in many ways, leaving them unprepared for sexual lives as adults. To analyze the state of sex education in Ohio, this paper will look at sex education throughout Ohio both in law and in practice. I will then explore the impact of these minimal sex education laws on …
Ionic Liquid-Solvated Chitosan Nanoparticles As A Novel Method Of Treating Atopic Dermatitis, Leslie Bell
Ionic Liquid-Solvated Chitosan Nanoparticles As A Novel Method Of Treating Atopic Dermatitis, Leslie Bell
Honors Theses
Atopic dermatitis, or eczema, is an inflammatory skin disease resulting in dry, red, and itchy skin that affects almost 20% of the population of the Western world. This disease creates a physical, emotional, as well as financial burden on those affected, as well as their families. Current treatment options are only somewhat effective, and do not have a long duration of release and therefore efficiency. Furthermore, treatment plans involving corticosteroids need to be closely regulated to monitor side effects such as skin thinning. Other options include topical tacrolimus, emollients, and oral antihistamines, each with varied side effects. This project is …
An Investigation Of Chronic Pain As A Much-Neglected Symptom Of Hypermobile Ehlers-Danlos Syndrome, Sydney Collins
An Investigation Of Chronic Pain As A Much-Neglected Symptom Of Hypermobile Ehlers-Danlos Syndrome, Sydney Collins
Honors Theses
Ehlers Danlos Syndrome is a group of heritable loose connective tissue disorders with 13 distinguished subtypes. The hypermobile type of Ehlers Danlos Syndrome (hEDS) is the most common subtype and is caused by a genetic mutation that leads to defective collagen fibrils. This leads to joint instability and hypermobility, skin elasticity, widespread pain, fatigue, and generalized tissue fragility. Chronic pain is reported to be a symptom in as high as 92% of the hEDS population (Voermans et al., 2010); despite this prevalence, there is a significant lack of research, awareness, and treatment standardization regarding pain in hEDS. This literature review …
Combined Clinical Audits And Low-Dose, High-Frequency, In-Service Training Of Health Care Providers And Community Health Workers To Improve Maternal And Newborn Health In Mali: Protocol For A Pragmatic Cluster Randomized Trial, David Zombre, Jean-Luc Kortenaar, Farhana Zareef, Moussa Doumbia, Sekou Doumbia, Fadima Haidara, Katie Mclaughlin, Samba Sow, Zulfiqar Ahmed Bhutta, Diego G. Bassani
Combined Clinical Audits And Low-Dose, High-Frequency, In-Service Training Of Health Care Providers And Community Health Workers To Improve Maternal And Newborn Health In Mali: Protocol For A Pragmatic Cluster Randomized Trial, David Zombre, Jean-Luc Kortenaar, Farhana Zareef, Moussa Doumbia, Sekou Doumbia, Fadima Haidara, Katie Mclaughlin, Samba Sow, Zulfiqar Ahmed Bhutta, Diego G. Bassani
Centre of Excellence in Women and Child Health
Background: Although most births in Mali occur in health facilities, a substantial number of newborns still die during delivery and within the first 7 days of life, mainly because of existing training deficiencies and the challenges of maintaining intrapartum and postpartum care skills.
Objective: This trial aims to assess the effectiveness and cost-effectiveness of an intervention combining clinical audits and low-dose, high-frequency (LDHF) in-service training of health care providers and community health workers to reduce perinatal mortality.
Methods: The study is a three-arm cluster randomized controlled trial in the Koulikoro region in Mali. The units of randomization are each of …
Intra-Tumoral Nerve-Tracing In A Novel Syngeneic Model Of High-Grade Serous Ovarian Carcinoma, Jeffrey L Barr, Allison Kruse, Anthony C Restaino, Natalia Tulina, Sarah Stuckelberger, Samuel J Vermeer, Caitlin S Williamson, Daniel W Vermeer, Marianna Madeo, Jillian Stamp, Maria Bell, Mark Morgan, Ju-Yoon Yoon, Marilyn A Mitchell, Anna Budina, Dalia K Omran, Lauren E Schwartz, Ronny Drapkin, Paola D Vermeer
Intra-Tumoral Nerve-Tracing In A Novel Syngeneic Model Of High-Grade Serous Ovarian Carcinoma, Jeffrey L Barr, Allison Kruse, Anthony C Restaino, Natalia Tulina, Sarah Stuckelberger, Samuel J Vermeer, Caitlin S Williamson, Daniel W Vermeer, Marianna Madeo, Jillian Stamp, Maria Bell, Mark Morgan, Ju-Yoon Yoon, Marilyn A Mitchell, Anna Budina, Dalia K Omran, Lauren E Schwartz, Ronny Drapkin, Paola D Vermeer
Faculty, Staff and Student Publications
Dense tumor innervation is associated with enhanced cancer progression and poor prognosis. We observed innervation in breast, prostate, pancreatic, lung, liver, ovarian, and colon cancers. Defining innervation in high-grade serous ovarian carcinoma (HGSOC) was a focus since sensory innervation was observed whereas the normal tissue contains predominantly sympathetic input. The origin, specific nerve type, and the mechanisms promoting innervation and driving nerve-cancer cell communications in ovarian cancer remain largely unknown. The technique of neuro-tracing enhances the study of tumor innervation by offering a means for identification and mapping of nerve sources that may directly and indirectly affect the tumor microenvironment. …
Radioembolization With Chemotherapy For Colorectal Liver Metastases: A Randomized, Open-Label, International, Multicenter, Phase Iii Trial, Mary F Mulcahy, Armeen Mahvash, Marc Pracht, Amir H Montazeri, Steve Bandula, Robert C G Martin, Ken Herrmann, Ewan Brown, Darryl Zuckerman, Gregory Wilson, Tae-You Kim, Andrew Weaver, Paul Ross, William P Harris, Janet Graham, Jamie Mills, Alfonso Yubero Esteban, Matthew S Johnson, Constantinos T Sofocleous, Siddharth A Padia, Robert J Lewandowski, Etienne Garin, Philip Sinclair, Riad Salem
Radioembolization With Chemotherapy For Colorectal Liver Metastases: A Randomized, Open-Label, International, Multicenter, Phase Iii Trial, Mary F Mulcahy, Armeen Mahvash, Marc Pracht, Amir H Montazeri, Steve Bandula, Robert C G Martin, Ken Herrmann, Ewan Brown, Darryl Zuckerman, Gregory Wilson, Tae-You Kim, Andrew Weaver, Paul Ross, William P Harris, Janet Graham, Jamie Mills, Alfonso Yubero Esteban, Matthew S Johnson, Constantinos T Sofocleous, Siddharth A Padia, Robert J Lewandowski, Etienne Garin, Philip Sinclair, Riad Salem
Faculty, Staff and Student Publications
PURPOSE: To study the impact of transarterial Yttrium-90 radioembolization (TARE) in combination with second-line systemic chemotherapy for colorectal liver metastases (CLM).
METHODS: In this international, multicenter, open-label phase III trial, patients with CLM who progressed on oxaliplatin- or irinotecan-based first-line therapy were randomly assigned 1:1 to receive second-line chemotherapy with or without TARE. The two primary end points were progression-free survival (PFS) and hepatic PFS (hPFS), assessed by blinded independent central review. Random assignment was performed using a web- or voice-based system stratified by unilobar or bilobar disease, oxaliplatin- or irinotecan-based first-line chemotherapy, and
RESULTS: Four hundred twenty-eight patients from …